AU2013255751B2 - GIP-GLP-1 dual agonist compounds and methods - Google Patents
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- AU2013255751B2 AU2013255751B2 AU2013255751A AU2013255751A AU2013255751B2 AU 2013255751 B2 AU2013255751 B2 AU 2013255751B2 AU 2013255751 A AU2013255751 A AU 2013255751A AU 2013255751 A AU2013255751 A AU 2013255751A AU 2013255751 B2 AU2013255751 B2 AU 2013255751B2
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- C07K14/575—Hormones
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- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
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Landscapes
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| US201361765561P | 2013-02-15 | 2013-02-15 | |
| US61/765,561 | 2013-02-15 | ||
| PCT/EP2013/059319 WO2013164483A1 (en) | 2012-05-03 | 2013-05-03 | Gip-glp-1 dual agonist compounds and methods |
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| AU2013255751A1 AU2013255751A1 (en) | 2014-12-18 |
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| CA2767792A1 (en) | 2009-07-13 | 2011-01-20 | Zealand Pharma A/S | Acylated glucagon analogues |
| IN2014MN02304A (enExample) | 2012-05-03 | 2015-08-07 | Zealand Pharma As | |
| DK2875043T3 (en) | 2012-07-23 | 2017-03-27 | Zealand Pharma As | glucagon |
| TWI608013B (zh) | 2012-09-17 | 2017-12-11 | 西蘭製藥公司 | 升糖素類似物 |
| UA116217C2 (uk) | 2012-10-09 | 2018-02-26 | Санофі | Пептидна сполука як подвійний агоніст рецепторів glp1-1 та глюкагону |
| WO2014096179A1 (en) * | 2012-12-19 | 2014-06-26 | Novo Nordisk A/S | Novel glp-1 receptor agonists with cholesterol efflux activity |
| WO2014096149A1 (en) * | 2012-12-21 | 2014-06-26 | Sanofi | Exendin-4 Derivatives |
| AP2015008781A0 (en) | 2013-05-28 | 2015-10-31 | Takeda Pharmaceutical | Peptide compound |
| US9988429B2 (en) | 2013-10-17 | 2018-06-05 | Zealand Pharma A/S | Glucagon analogues |
| HRP20181505T1 (hr) | 2013-10-17 | 2018-11-02 | Zealand Pharma A/S | Acilirani analozi glukagona |
| EP3066117B1 (en) | 2013-11-06 | 2019-01-02 | Zealand Pharma A/S | Glucagon-glp-1-gip triple agonist compounds |
| EA035466B9 (ru) * | 2013-11-06 | 2020-08-17 | Зилэнд Фарма А/С | Соединения и способы на основе двойного агониста гип и гпп-1 |
| CA2932477C (en) | 2013-12-06 | 2023-10-10 | Baikang (Suzhou) Co., Ltd | Bioreversable promoieties for nitrogen-containing and hydroxyl-containing drugs |
| CA2965732A1 (en) * | 2014-10-29 | 2016-05-06 | Zealand Pharma A/S | Gip agonist compounds and methods |
| JOP20200119A1 (ar) * | 2015-01-09 | 2017-06-16 | Lilly Co Eli | مركبات مساعد مشترك من gip وglp-1 |
| RU2735762C2 (ru) | 2015-04-16 | 2020-11-06 | Зилэнд Фарма А/С | Ацилированный аналог глюкагона, его применение и способы получения |
| US10905744B2 (en) | 2015-10-07 | 2021-02-02 | Cyprumed Gmbh | Pharmaceutical formulations for the oral delivery of peptide drugs |
| TWI622596B (zh) | 2015-10-26 | 2018-05-01 | 美國禮來大藥廠 | 升糖素受體促效劑 |
| WO2017204219A1 (ja) * | 2016-05-24 | 2017-11-30 | 武田薬品工業株式会社 | ペプチド化合物 |
| WO2018065634A1 (en) | 2016-10-07 | 2018-04-12 | Cyprumed Gmbh | Pharmaceutical compositions for the nasal delivery of peptide or protein drugs |
| GB201620611D0 (en) | 2016-12-05 | 2017-01-18 | Univ Of Lancaster | Treatment of neurological diseases |
| EP3551202B1 (en) | 2016-12-06 | 2024-01-24 | INSERM (Institut National de la Santé et de la Recherche Médicale) | Methods of enhancing the potency of incretin-based drugs in subjects in need thereof |
| JOP20180028A1 (ar) | 2017-03-31 | 2019-01-30 | Takeda Pharmaceuticals Co | مركب ببتيد |
| WO2019140030A1 (en) | 2018-01-12 | 2019-07-18 | Eli Lilly And Company | Combination therapy |
| US10577905B2 (en) | 2018-02-12 | 2020-03-03 | Eagle Technology, Llc | Hydrocarbon resource recovery system and RF antenna assembly with latching inner conductor and related methods |
| US20210087250A1 (en) | 2018-04-06 | 2021-03-25 | Cyprumed Gmbh | Pharmaceutical compositions for the transmucosal delivery of therapeutic peptides and proteins |
| MX2020011427A (es) | 2018-05-04 | 2020-12-07 | Novo Nordisk As | Derivados del polipeptido insulinotropico dependiente de la glucosa (gip) y usos de estos. |
| TWI705820B (zh) | 2018-06-22 | 2020-10-01 | 美商美國禮來大藥廠 | Gip/glp1促效劑組合物 |
| PT3826662T (pt) | 2018-07-23 | 2024-10-30 | Lilly Co Eli | Método de utilização de um coagonista gip/glp1 para diabetes |
| UA128697C2 (uk) | 2018-07-23 | 2024-10-02 | Елі Ліллі Енд Компані | Способи застосування коагоніста gip/glp-1 для терапії |
| AU2019311000B2 (en) | 2018-07-23 | 2023-02-02 | Eli Lilly And Company | GIP/GLP1 co-agonist compounds |
| EP3856768A2 (en) * | 2018-09-24 | 2021-08-04 | Takeda Pharmaceutical Company Limited | Gip receptor agonist peptide compounds and uses thereof |
| CN113614102B (zh) * | 2019-01-07 | 2024-08-13 | 鸿绪生物医药科技（北京）有限公司 | 新型多肽及其治疗用途 |
| CN112351994B (zh) * | 2019-04-11 | 2024-06-07 | 江苏豪森药业集团有限公司 | 一种多受体激动剂及其医药用途 |
| AR119471A1 (es) | 2019-08-01 | 2021-12-22 | Lilly Co Eli | Compuestos agonistas de gipr |
| KR102812908B1 (ko) | 2019-08-19 | 2025-05-28 | 일라이 릴리 앤드 캄파니 | 인크레틴 유사체의 제조 방법 |
| US20230000950A1 (en) | 2019-10-04 | 2023-01-05 | Hanmi Pharm. Co., Ltd. | Composition comprising glucagon and glp-1 and gip receptor dual agonist and therapeutic use of same |
| CN110684082B (zh) | 2019-10-08 | 2021-12-10 | 江苏诺泰澳赛诺生物制药股份有限公司 | Gip和glp-1双激动多肽化合物及药学上可接受的盐与用途 |
| CN114641303A (zh) | 2019-11-11 | 2022-06-17 | 勃林格殷格翰国际有限公司 | Npy2受体激动剂 |
| CN113383014B (zh) * | 2019-11-15 | 2024-06-18 | 江苏豪森药业集团有限公司 | 双受体重激动剂化合物及其药物组合物 |
| WO2021143810A1 (zh) * | 2020-01-17 | 2021-07-22 | 珠海联邦制药股份有限公司 | 多肽化合物及其应用 |
| TWI770781B (zh) * | 2020-01-23 | 2022-07-11 | 美商美國禮來大藥廠 | Gip/glp1共促效劑化合物 |
| AR121650A1 (es) * | 2020-03-25 | 2022-06-22 | Takeda Pharmaceuticals Co | Dosificación qd de compuestos peptídicos agonistas del receptor de gip y sus usos |
| TW202216746A (zh) * | 2020-06-22 | 2022-05-01 | 印度商太陽製藥工業有限公司 | 長效型ｇｌｐ－１／ｇｉｐ雙重促效劑 |
| IL299707A (en) | 2020-07-22 | 2023-03-01 | Novo Nordisk As | Co-agonists for GLP-1 and GIP receptors |
| KR102446310B1 (ko) | 2020-07-22 | 2022-09-23 | 노보 노르디스크 에이/에스 | 경구 전달에 적합한 glp-1 및 gip 수용체에서의 공-작용제 |
| IL300239A (en) | 2020-08-07 | 2023-03-01 | Boehringer Ingelheim Int | Soluble NPY2 receptor agonists |
| US20240041983A1 (en) | 2020-09-07 | 2024-02-08 | Cyprumed Gmbh | Improved pharmaceutical formulations of glp-1 receptor agonists |
| AU2021361263A1 (en) * | 2020-10-17 | 2023-02-16 | Sun Pharmaceutical Industries Limited | GLP-1/GIP dual agonists |
| CA3200881C (en) * | 2020-12-02 | 2025-05-20 | Dongbao Purple Star (Hangzhou) Biopharmaceutical Co., Ltd | LACTAM MODIFIED POLYPEPTIDE COMPOUNDS |
| CN114617956B (zh) * | 2020-12-10 | 2023-10-03 | 江苏中新医药有限公司 | 一种高效降糖的蛋白质药物 |
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| IL311411A (en) | 2021-09-15 | 2024-05-01 | Viking Therapeutics Inc | Preparations and methods for the treatment of metabolic and liver disorders |
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| CN116947978A (zh) * | 2022-04-19 | 2023-10-27 | 北京惠之衡生物科技有限公司 | 一种glp-1和gip受体共激动多肽衍生物及其盐和制剂 |
| KR20250037523A (ko) | 2022-07-13 | 2025-03-17 | 항저우 종메이화동 파마슈티칼 컴퍼니 리미티드 | Glp-1/gip 이중 효능제, 이의 제조 방법 및 이의 용도 |
| CA3261877A1 (en) * | 2022-07-15 | 2024-01-18 | Pep2Tango Therapeutics Inc. | COMPOSITIONS COMPRISING MULTI-AGONIST PEPTIDES, MANUFACTURING PROCESSES AND METHODS OF USE |
| WO2024020388A1 (en) * | 2022-07-20 | 2024-01-25 | Viking Therapeutics, Inc. | Pharmaceutical formulations and methods for the treatment of metabolic and liver disorders |
| KR20250057847A (ko) | 2022-08-29 | 2025-04-29 | 일라이 릴리 앤드 캄파니 | 경구 전달용 조성물 |
| EP4587462A1 (en) | 2022-09-15 | 2025-07-23 | Eli Lilly and Company | Gip and glp-1 dual agonist compounds |
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| CN121001710A (zh) | 2022-12-30 | 2025-11-21 | 阿尔吉法玛公司 | 提高口服多肽治疗剂的全身生物利用度的组合物和方法 |
| CN120981479A (zh) | 2023-01-31 | 2025-11-18 | 伊莱利利公司 | Gip/glp1/gcg三受体激动剂及其用途 |
| WO2024165571A2 (en) | 2023-02-06 | 2024-08-15 | E-Therapeutics Plc | Inhibitors of expression and/or function |
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