IN2012DN01521A - - Google Patents
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- Publication number
- IN2012DN01521A IN2012DN01521A IN1521DEN2012A IN2012DN01521A IN 2012DN01521 A IN2012DN01521 A IN 2012DN01521A IN 1521DEN2012 A IN1521DEN2012 A IN 1521DEN2012A IN 2012DN01521 A IN2012DN01521 A IN 2012DN01521A
- Authority
- IN
- India
- Prior art keywords
- host
- schizosaccharomyces pombe
- transformant
- inactivated
- deleted
- Prior art date
Links
- 241000235347 Schizosaccharomyces pombe Species 0.000 abstract 2
- 108700023483 L-lactate dehydrogenases Proteins 0.000 abstract 1
- 108010011939 Pyruvate Decarboxylase Proteins 0.000 abstract 1
- 108091008053 gene clusters Proteins 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
- C12N1/14—Fungi; Culture media therefor
- C12N1/16—Yeasts; Culture media therefor
- C12N1/18—Baker's yeast; Brewer's yeast
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/52—Genes encoding for enzymes or proenzymes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/80—Vectors or expression systems specially adapted for eukaryotic hosts for fungi
- C12N15/81—Vectors or expression systems specially adapted for eukaryotic hosts for fungi for yeasts
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/0004—Oxidoreductases (1.)
- C12N9/0006—Oxidoreductases (1.) acting on CH-OH groups as donors (1.1)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P7/00—Preparation of oxygen-containing organic compounds
- C12P7/40—Preparation of oxygen-containing organic compounds containing a carboxyl group including Peroxycarboxylic acids
- C12P7/56—Lactic acid
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Mycology (AREA)
- Plant Pathology (AREA)
- Biophysics (AREA)
- Physics & Mathematics (AREA)
- Medicinal Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Virology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Botany (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Enzymes And Modification Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2009192271 | 2009-08-21 | ||
| PCT/JP2010/063888 WO2011021629A1 (ja) | 2009-08-21 | 2010-08-17 | 形質転換体およびその製造方法、ならびに乳酸の製造方法 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| IN2012DN01521A true IN2012DN01521A (enExample) | 2015-06-05 |
Family
ID=43607080
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IN1521DEN2012 IN2012DN01521A (enExample) | 2009-08-21 | 2010-08-17 |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US9284561B2 (enExample) |
| EP (1) | EP2468860B1 (enExample) |
| JP (1) | JP5772594B2 (enExample) |
| KR (1) | KR20120051705A (enExample) |
| CN (1) | CN102498209A (enExample) |
| IN (1) | IN2012DN01521A (enExample) |
| WO (1) | WO2011021629A1 (enExample) |
Families Citing this family (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103392004A (zh) * | 2011-02-21 | 2013-11-13 | 旭硝子株式会社 | 乳酸的制造方法 |
| CN104583396A (zh) * | 2012-08-24 | 2015-04-29 | 旭硝子株式会社 | 转化体及其制造方法、以及乳酸的制造方法 |
| CN105189762A (zh) * | 2013-03-28 | 2015-12-23 | 旭硝子株式会社 | 化工产品的制造方法及制造装置 |
| RU2539092C1 (ru) * | 2013-09-27 | 2015-01-10 | Федеральное государственное унитарное предприятие "Государственный научно-исследовательский институт генетики и селекции промышленных микроорганизмов" (ФГУП "ГосНИИгенетика") | РЕКОМБИНАНТНЫЙ ШТАММ ДРОЖЖЕЙ Schizosaccharomyces pombe - ПРОДУЦЕНТ МОЛОЧНОЙ КИСЛОТЫ |
| JP6488666B2 (ja) * | 2013-11-22 | 2019-03-27 | Ａｇｃ株式会社 | クローニングベクター、発現ベクターおよび形質転換体の製造方法 |
| JP6499587B2 (ja) * | 2013-11-22 | 2019-04-10 | Ｊｍｔｃエンザイム株式会社 | 形質転換体およびその製造方法、ならびに乳酸の製造方法 |
| EP2977471A1 (en) * | 2014-07-23 | 2016-01-27 | PURAC Biochem BV | Genetic modification of (S)-lactic acid producing thermophilic bacteria |
| JP2017205019A (ja) * | 2014-09-19 | 2017-11-24 | 旭硝子株式会社 | 有機酸の製造方法 |
| US10214754B2 (en) * | 2014-10-10 | 2019-02-26 | Jmtc Enzyme Corporation | Transformant and its production process, and method for producing lactic acid |
| CA3004176A1 (en) | 2015-11-24 | 2017-06-01 | Cargill, Incorporated | Genetically modified yeasts and fermentation processes using genetically modified yeasts |
| EP3178313A1 (en) | 2015-12-09 | 2017-06-14 | Leibniz-Institut für Pflanzenbiochemie | Gene and protein for the synthesis of oxidized zingiberene derivatives |
| RU2614233C1 (ru) * | 2015-12-22 | 2017-03-23 | Федеральное государственное бюджетное учреждение "Государственный научно-исследовательский институт генетики и селекции промышленных микроорганизмов" (ФГБУ "ГосНИИгенетика") | Трансформант дрожжей Schizosaccharomyces pombe, продуцирующий молочную кислоту (варианты), способ его получения (варианты), способ микробиологического синтеза молочной кислоты с использованием такого трансформанта |
| RU2652877C9 (ru) * | 2016-12-21 | 2018-06-26 | Федеральное государственное бюджетное учреждение "Государственный научно-исследовательский институт генетики и селекции промышленных микроорганизмов Национального исследовательского центра "Курчатовский институт" (НИЦ "Курчатовский институт" - ГосНИИгенетика) | Способ модификации дрожжей Schizosaccharomyces pombe с помощью Cre-lox системы бактериофага Р1, трансформант, полученный таким способом |
| RU2650669C1 (ru) * | 2016-12-21 | 2018-04-16 | Федеральное государственное бюджетное учреждение "Государственный научно-исследовательский институт генетики и селекции промышленных микроорганизмов Национального исследовательского центра "Курчатовский институт" (НИЦ "Курчатовский институт" - ГосНИИгенетика) | Штамм Schizosaccharomyces pombe - продуцент молочной кислоты |
| KR102140596B1 (ko) | 2018-04-17 | 2020-08-04 | 에스케이이노베이션 주식회사 | 유기산 내성 효모 유래 신규 프로모터 및 이를 이용한 목적유전자의 발현방법 |
| EA202190469A1 (ru) * | 2018-08-09 | 2021-06-28 | Джуно Терапьютикс, Инк. | Способы оценки интегрированных нуклеиновых кислот |
| CN109280652A (zh) * | 2018-09-13 | 2019-01-29 | 四川自豪时代药业有限公司 | 一种外源高表达乳酸脱氢酶突变体的高密度发酵方法 |
| KR102736070B1 (ko) | 2018-10-08 | 2024-12-02 | 에스케이이노베이션 주식회사 | 알코올 생성이 억제된 재조합 내산성 효모 및 이를 이용한 젖산의 제조방법 |
| EP4025700A1 (en) | 2019-09-05 | 2022-07-13 | Leibniz-Institut für Pflanzenbiochemie (IPB) | Nucleic acids, proteins and processes for producing piperine and other amides |
| KR20210041903A (ko) | 2019-10-08 | 2021-04-16 | 에스케이이노베이션 주식회사 | 락테이트 대사 및 알코올 생성이 억제된 재조합 내산성 효모 및 이를 이용한 젖산의 제조방법 |
| KR20210128742A (ko) | 2020-04-17 | 2021-10-27 | 에스케이이노베이션 주식회사 | 글리세롤 생성이 억제된 재조합 내산성 효모 및 이를 이용한 젖산의 제조방법 |
| KR20210158676A (ko) | 2020-06-24 | 2021-12-31 | 에스케이이노베이션 주식회사 | 젖산 생산능이 증가된 재조합 내산성 효모 |
| WO2023004336A1 (en) * | 2021-07-22 | 2023-01-26 | Archer Daniels Midland Company | A genetically engineered yeast producing lactic acid |
Family Cites Families (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2776085B2 (ja) | 1990-09-14 | 1998-07-16 | 旭硝子株式会社 | ベクター |
| JP3689920B2 (ja) | 1993-10-05 | 2005-08-31 | 旭硝子株式会社 | マルチクローニングベクター、発現ベクター、および異種蛋白質の生産 |
| DE69435058T2 (de) | 1993-10-05 | 2008-04-30 | Asahi Glass Co., Ltd. | Multicloning-vektor, expressionsvektor und herstellung von fremdproteinen unter verwendung des expressionsvektors |
| EP0773296B1 (en) | 1995-02-03 | 2006-09-13 | Asahi Glass Company Ltd. | Secretory signal gene and expression vector having the same |
| JPH10234375A (ja) | 1997-02-28 | 1998-09-08 | Asahi Glass Co Ltd | マルチクローニングベクター |
| IT1294728B1 (it) | 1997-09-12 | 1999-04-12 | Biopolo S C A R L | Ceppi di lievito per la riproduzione di acido lattico |
| US6130070A (en) | 1997-10-31 | 2000-10-10 | Asahi Glass Company Ltd. | Induction promoter gene and secretory signal gene usable in Schizosaccharomyces pombe, expression vectors having the same, and use thereof |
| US20070031950A1 (en) | 1998-09-11 | 2007-02-08 | Winkler Aaron A | Production of D-lactic acid with yeast |
| JP4305998B2 (ja) | 1999-03-18 | 2009-07-29 | 旭硝子株式会社 | シゾサッカロミセス・ポンベの形質転換方法 |
| JP2001204464A (ja) | 2000-01-27 | 2001-07-31 | Toyota Motor Corp | 乳酸の製造方法 |
| US7141410B2 (en) * | 2000-11-22 | 2006-11-28 | Natureworks Llc | Methods and materials for the production of organic products in cells of Candida species |
| JP4211603B2 (ja) * | 2001-05-29 | 2009-01-21 | 旭硝子株式会社 | シゾサッカロマイセス・ポンベ（Ｓｃｈｉｚｏｓａｃｃｈａｒｏｍｙｃｅｓｐｏｍｂｅ）宿主の構築方法および異種タンパク質の製造方法 |
| US7405068B2 (en) * | 2003-05-02 | 2008-07-29 | Tate & Lyle Ingredients Americas, Inc. | Pyruvate producing yeast strain |
| US20050112737A1 (en) | 2003-11-20 | 2005-05-26 | A. E. Staley Manufacturing Co. | Lactic acid producing yeast |
| JP5248735B2 (ja) | 2004-01-19 | 2013-07-31 | 旭硝子株式会社 | 酵母の形質転換方法 |
| JP2006006271A (ja) * | 2004-06-29 | 2006-01-12 | Toyota Central Res & Dev Lab Inc | 乳酸生産酵母および乳酸生産方法 |
| EP2182060B1 (en) | 2005-08-03 | 2012-10-24 | Asahi Glass Company, Limited | Transformed yeast host cells and method of producing foreign protein |
| EP1930423A4 (en) | 2005-08-29 | 2009-12-09 | Asahi Glass Co Ltd | EXPRESSION VECTOR, TRANSFORMANT WITH THE EXPRESSION VECTOR INTRODUCED THEREIN AND METHOD FOR THE PRODUCTION OF HETEROLOGICAL PROTEIN |
| JP5200542B2 (ja) * | 2005-11-29 | 2013-06-05 | 旭硝子株式会社 | 染色体改変方法 |
| JP5329055B2 (ja) | 2006-07-24 | 2013-10-30 | 東レ株式会社 | 変異型ピルビン酸脱炭酸酵素５遺伝子を有する酵母及び乳酸の製造方法 |
| JP2011507532A (ja) * | 2007-12-23 | 2011-03-10 | ジーヴォ，インコーポレイテッド | 高収率でイソブタノールを産生する酵母生物 |
-
2010
- 2010-08-17 CN CN2010800371957A patent/CN102498209A/zh active Pending
- 2010-08-17 KR KR1020127004318A patent/KR20120051705A/ko not_active Withdrawn
- 2010-08-17 JP JP2011527683A patent/JP5772594B2/ja active Active
- 2010-08-17 WO PCT/JP2010/063888 patent/WO2011021629A1/ja not_active Ceased
- 2010-08-17 IN IN1521DEN2012 patent/IN2012DN01521A/en unknown
- 2010-08-17 EP EP10809970.6A patent/EP2468860B1/en active Active
-
2012
- 2012-02-21 US US13/401,197 patent/US9284561B2/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| JPWO2011021629A1 (ja) | 2013-01-24 |
| EP2468860A1 (en) | 2012-06-27 |
| EP2468860A4 (en) | 2013-04-03 |
| US9284561B2 (en) | 2016-03-15 |
| CN102498209A (zh) | 2012-06-13 |
| EP2468860B1 (en) | 2015-11-25 |
| JP5772594B2 (ja) | 2015-09-02 |
| EP2468860A9 (en) | 2012-12-26 |
| KR20120051705A (ko) | 2012-05-22 |
| US20120214214A1 (en) | 2012-08-23 |
| WO2011021629A1 (ja) | 2011-02-24 |
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