CN1020944C
(zh)
|
1990-01-30 |
1993-05-26 |
阿图尔-费希尔股份公司费希尔厂 |
紧固件
|
FR2686899B1
(fr)
|
1992-01-31 |
1995-09-01 |
Rhone Poulenc Rorer Sa |
Nouveaux polypeptides biologiquement actifs, leur preparation et compositions pharmaceutiques les contenant.
|
US6515117B2
(en)
*
|
1999-10-12 |
2003-02-04 |
Bristol-Myers Squibb Company |
C-aryl glucoside SGLT2 inhibitors and method
|
SK9292002A3
(en)
*
|
1999-12-28 |
2002-10-08 |
Ajinomoto Kk |
Oral preparations for diabetes
|
US6627611B2
(en)
*
|
2000-02-02 |
2003-09-30 |
Kotobuki Pharmaceutical Co Ltd |
C-glycosides and preparation of thereof as antidiabetic agents
|
EP2067488A1
(en)
|
2000-04-12 |
2009-06-10 |
Human Genome Sciences, Inc. |
Albumin fusion proteins
|
FR2809310B1
(fr)
*
|
2000-05-26 |
2004-02-13 |
Centre Nat Rech Scient |
Utilisation de derives de biguanide pour fabriquer un medicament ayant un effet cicatrisant
|
DK1333887T3
(da)
*
|
2000-10-30 |
2006-11-13 |
Ortho Mcneil Pharm Inc |
Kombinationsbehandling omfattende antidiabetiske og antikonvulsive midler
|
US20030224047A1
(en)
*
|
2001-02-15 |
2003-12-04 |
Franz G. Andrew |
Levothyroxine compositions and methods
|
US6555581B1
(en)
|
2001-02-15 |
2003-04-29 |
Jones Pharma, Inc. |
Levothyroxine compositions and methods
|
US20030032675A1
(en)
*
|
2001-02-15 |
2003-02-13 |
Franz G. Andrew |
Manufacture of thyroid hormone tablets having consistent active moiety amounts
|
US7067148B2
(en)
*
|
2001-02-15 |
2006-06-27 |
King Pharmaceutical Research & Development, Inc. |
Stabilized pharmaceutical and thyroid hormone compositions and method of preparation
|
US6936590B2
(en)
*
|
2001-03-13 |
2005-08-30 |
Bristol Myers Squibb Company |
C-aryl glucoside SGLT2 inhibitors and method
|
EP2065044A1
(en)
*
|
2001-04-04 |
2009-06-03 |
Ortho-McNeil-Janssen Pharmaceuticals, Inc. |
Combination therapy comprising glucose reabsorption inhibitors and PPAR modulators
|
ATE318272T1
(de)
*
|
2001-04-11 |
2006-03-15 |
Bristol Myers Squibb Co |
Aminosäurekomplexe von c-arylglycosiden zur behandlung von diabetes und verfahren
|
WO2003011880A1
(fr)
*
|
2001-07-31 |
2003-02-13 |
Kissei Pharmaceutical Co., Ltd. |
Derive de glucopyranosyloxybenzylbenzene, composition medicinale contenant ce derive, usage medicinal de cette composition et produit intermediaire pour produire cette composition
|
US20030190349A1
(en)
*
|
2001-08-10 |
2003-10-09 |
Franz G. Andrew |
Methods of stabilizing pharmaceutical compositions
|
US20030198667A1
(en)
*
|
2001-08-10 |
2003-10-23 |
Franz Andrew G. |
Methods of producing dispersible pharmaceutical compositions
|
US20030180353A1
(en)
*
|
2001-08-10 |
2003-09-25 |
Franz G. Andrew |
Stabilized pharmaceutical compositions
|
US20030195253A1
(en)
*
|
2001-08-14 |
2003-10-16 |
Franz G. Andrew |
Unadsorbed levothyroxine pharmaceutical compositions, methods of making and methods of administration
|
US20030199586A1
(en)
*
|
2001-08-14 |
2003-10-23 |
Franz G. Andrew |
Unique levothyroxine aqueous materials
|
US7101569B2
(en)
|
2001-08-14 |
2006-09-05 |
Franz G Andrew |
Methods of administering levothyroxine pharmaceutical compositions
|
US20030199587A1
(en)
*
|
2001-08-14 |
2003-10-23 |
Franz G. Andrew |
Levothyroxine compositions having unique Cmax properties
|
US20030203967A1
(en)
*
|
2001-08-14 |
2003-10-30 |
Franz G. Andrew |
Levothyroxine compositions having unique Tmax properties
|
US20030198672A1
(en)
*
|
2001-08-14 |
2003-10-23 |
Franz G. Andrew |
Levothyroxine compositions having unique triidothyronine plasma AUC properties
|
US20030190359A1
(en)
*
|
2001-10-29 |
2003-10-09 |
Franz G. Andrew |
Levothyroxine compositions having unique triiodothyronine Tmax properties
|
US6806381B2
(en)
*
|
2001-11-02 |
2004-10-19 |
Bristol-Myers Squibb Company |
Process for the preparation of aniline-derived thyroid receptor ligands
|
EP1443919A4
(en)
*
|
2001-11-16 |
2006-03-22 |
Bristol Myers Squibb Co |
DOUBLE INHIBITORS OF THE FATTY ACID BINDING PROTEIN OF THE ADIPOCYTES AND THE FATTY ACID BINDING PROTEIN OF KERATINOCYTES
|
WO2005003296A2
(en)
|
2003-01-22 |
2005-01-13 |
Human Genome Sciences, Inc. |
Albumin fusion proteins
|
WO2003060071A2
(en)
|
2001-12-21 |
2003-07-24 |
Human Genome Sciences, Inc. |
Albumin fusion proteins
|
EP1461069A2
(en)
*
|
2001-12-29 |
2004-09-29 |
Novo Nordisk A/S |
Combined use of a glp-1 compound and another drug for treating dyslipidemia
|
WO2003075911A1
(en)
*
|
2002-03-11 |
2003-09-18 |
Peter Zahradka |
Use of ppar alpha agonists for the treatment of vascular and renal diseases
|
US20050215489A1
(en)
*
|
2002-03-14 |
2005-09-29 |
Bayer Pharmaceuticals Corporation |
Methods of treating diabetes using pde 11a inhibitors
|
US7956041B2
(en)
|
2002-04-26 |
2011-06-07 |
Ajinomoto Co., Inc. |
Prophylactic and therapeutic agent of diabetes mellitus
|
AU2003231517A1
(en)
*
|
2002-04-26 |
2003-11-10 |
Ajinomoto Co., Inc. |
Preventive/remedy for diabetes
|
US7057046B2
(en)
|
2002-05-20 |
2006-06-06 |
Bristol-Myers Squibb Company |
Lactam glycogen phosphorylase inhibitors and method of use
|
TWI254635B
(en)
*
|
2002-08-05 |
2006-05-11 |
Yamanouchi Pharma Co Ltd |
Azulene derivative and salt thereof
|
JP4530855B2
(ja)
|
2002-10-04 |
2010-08-25 |
キッセイ薬品工業株式会社 |
ピラゾール誘導体、それを含有する医薬組成物、その医薬用途及びその製造中間体
|
US7098235B2
(en)
|
2002-11-14 |
2006-08-29 |
Bristol-Myers Squibb Co. |
Triglyceride and triglyceride-like prodrugs of glycogen phosphorylase inhibiting compounds
|
DE10258008B4
(de)
*
|
2002-12-12 |
2006-02-02 |
Sanofi-Aventis Deutschland Gmbh |
Heterocyclische Fluorglycosidderivate, diese Verbindungen enthaltende Arzneimittel und Verfahren zur Herstellung dieser Arzneimittel
|
DE10258007B4
(de)
*
|
2002-12-12 |
2006-02-09 |
Sanofi-Aventis Deutschland Gmbh |
Aromatische Fluorglycosidderivate, diese Verbindungen enthaltende Arzneimittel und Verfahren zur Herstellung dieser Arzneimittel
|
US7790681B2
(en)
|
2002-12-17 |
2010-09-07 |
Amylin Pharmaceuticals, Inc. |
Treatment of cardiac arrhythmias with GLP-1 receptor ligands
|
JP2006516257A
(ja)
|
2003-01-03 |
2006-06-29 |
ブリストル−マイヤーズ スクイブ カンパニー |
C−アリールグルコシドsglt2阻害剤の製造法
|
EP1457206A1
(en)
*
|
2003-03-13 |
2004-09-15 |
Fournier Laboratories Ireland Limited |
Combined use of a fibrate and orlistat for the treatment of obesity
|
PL1980560T3
(pl)
|
2003-03-14 |
2011-11-30 |
Astellas Pharma Inc |
Pochodne C-glikozydowe do leczenia cukrzycy
|
JP2004300102A
(ja)
|
2003-03-31 |
2004-10-28 |
Kissei Pharmaceut Co Ltd |
縮合複素環誘導体、それを含有する医薬組成物およびその医薬用途
|
CA2524134C
(en)
*
|
2003-04-28 |
2017-07-04 |
Sankyo Company Limited |
Adiponectin production enhancer
|
CA2524175C
(en)
*
|
2003-04-28 |
2016-06-14 |
Sankyo Company Limited |
Sugar intake-ability enhancer
|
US7459474B2
(en)
|
2003-06-11 |
2008-12-02 |
Bristol-Myers Squibb Company |
Modulators of the glucocorticoid receptor and method
|
RS20060320A
(en)
|
2003-08-01 |
2008-08-07 |
Janssen Pharmaceutica N.V., |
Substituted indazole-o-glucosides
|
US8785403B2
(en)
|
2003-08-01 |
2014-07-22 |
Mitsubishi Tanabe Pharma Corporation |
Glucopyranoside compound
|
EA011515B1
(ru)
|
2003-08-01 |
2009-04-28 |
Янссен Фармацевтика Н.В. |
Замещенные бензимидазол-, бензтриазол- и бензимидазолон-о-глюкозиды
|
CA2549015A1
(en)
|
2003-08-01 |
2005-02-10 |
Janssen Pharmaceutica N.V. |
Substituted fused heterocyclic c-glycosides
|
UA86042C2
(en)
|
2003-08-01 |
2009-03-25 |
Янссен Фармацевтика Н.В. |
Substituted indazole-o-glucosides
|
AU2004261664A1
(en)
*
|
2003-08-01 |
2005-02-10 |
Janssen Pharmaceutica N.V. |
Substituted indole-O-glucosides
|
SI1651658T2
(sl)
|
2003-08-01 |
2020-12-31 |
Mitsubishi Tanabe Pharma Corporation |
Nove spojine, ki imajo inhibitorno aktivnost proti transporterju, ki je odvisen od natrija
|
US7375090B2
(en)
|
2003-08-26 |
2008-05-20 |
Boehringer Ingelheim International Gmbh |
Glucopyranosyloxy-pyrazoles, pharmaceutical compositions containing these compounds, the use thereof and processed for the preparation thereof
|
US20050054731A1
(en)
*
|
2003-09-08 |
2005-03-10 |
Franco Folli |
Multi-system therapy for diabetes, the metabolic syndrome and obesity
|
US7371759B2
(en)
*
|
2003-09-25 |
2008-05-13 |
Bristol-Myers Squibb Company |
HMG-CoA reductase inhibitors and method
|
GB0322552D0
(en)
|
2003-09-26 |
2003-10-29 |
Astrazeneca Uk Ltd |
Therapeutic treatment
|
EP1687410A4
(en)
*
|
2003-10-07 |
2008-04-09 |
Isis Pharmaceuticals Inc |
ANTISENSE OLIGONUCLEOTIDE OPTIMIZED FOR KIDNEY TARGETING
|
US20050191653A1
(en)
*
|
2003-11-03 |
2005-09-01 |
Freier Susan M. |
Modulation of SGLT2 expression
|
AU2004288831B2
(en)
|
2003-11-12 |
2010-08-26 |
Phenomix Corporation |
Heterocyclic boronic acid compounds
|
US7420059B2
(en)
*
|
2003-11-20 |
2008-09-02 |
Bristol-Myers Squibb Company |
HMG-CoA reductase inhibitors and method
|
EP1581246B1
(en)
*
|
2003-12-17 |
2013-01-16 |
Amylin Pharmaceuticals, LLC |
Compositions for the treatment and prevention of nephropathy
|
JP2006514649A
(ja)
*
|
2003-12-17 |
2006-05-11 |
アミリン・ファーマシューティカルズ,インコーポレイテッド |
腎症の治療および予防のための組成物
|
US7371732B2
(en)
*
|
2003-12-22 |
2008-05-13 |
Boehringer Ingelheim International Gmbh |
Glucopyranosyloxy-substituted aromatic compounds, medicaments containing such compounds, their use and process for their manufacture
|
WO2005085265A1
(ja)
*
|
2004-03-04 |
2005-09-15 |
Kissei Pharmaceutical Co., Ltd. |
縮合ヘテロ環誘導体、それを含有する医薬組成物およびその医薬用途
|
CN1934103B
(zh)
*
|
2004-03-04 |
2011-06-01 |
橘生药品工业株式会社 |
稠杂环衍生物,包含稠杂环衍生物的药物组合物及其医药用途
|
BRPI0508830B8
(pt)
|
2004-03-16 |
2021-05-25 |
Boehringer Ingelheim Int |
derivados de benzeno substituídos por glucopiranosila, medicamentos contendo esses compostos, seu uso e processo para sua fabricação
|
JPWO2005095372A1
(ja)
*
|
2004-03-31 |
2008-02-21 |
キッセイ薬品工業株式会社 |
ナフタレン誘導体、それを含有する医薬組成物及びその医薬用途
|
WO2005095429A1
(ja)
*
|
2004-03-31 |
2005-10-13 |
Kissei Pharmaceutical Co., Ltd. |
フェノール誘導体、それを含有する医薬組成物及びその医薬用途
|
TW200602335A
(en)
*
|
2004-03-31 |
2006-01-16 |
Kissei Pharmaceutical |
Naphthalene derivative, medicinal composition containing the same, and medicinal use thereof
|
DE602005025755D1
(de)
|
2004-06-04 |
2011-02-17 |
Teva Pharma |
Irbesartan enthaltende pharmazeutische zusammensetzung
|
DE102004028241B4
(de)
*
|
2004-06-11 |
2007-09-13 |
Sanofi-Aventis Deutschland Gmbh |
Neue Fluorglykosidderivate von Pyrazolen, diese Verbindungen enthaltende Arzneimittel und Herstellung dieser Arzneimittel
|
US7393836B2
(en)
|
2004-07-06 |
2008-07-01 |
Boehringer Ingelheim International Gmbh |
D-xylopyranosyl-substituted phenyl derivatives, medicaments containing such compounds, their use and process for their manufacture
|
KR20070048188A
(ko)
*
|
2004-07-08 |
2007-05-08 |
아스텔라스세이야쿠 가부시키가이샤 |
아줄렌 유도체의 제조방법 및 이의 합성 중간체
|
US7572805B2
(en)
|
2004-07-14 |
2009-08-11 |
Bristol-Myers Squibb Company |
Pyrrolo(oxo)isoquinolines as 5HT ligands
|
WO2006009149A1
(ja)
*
|
2004-07-21 |
2006-01-26 |
Kissei Pharmaceutical Co., Ltd. |
肝臓脂肪の異常蓄積に起因する疾患の進展抑制剤
|
TW200606129A
(en)
|
2004-07-26 |
2006-02-16 |
Chugai Pharmaceutical Co Ltd |
Novel cyclohexane derivative, its prodrug, its salt and diabetic therapeutic agent containing the same
|
JP2008508213A
(ja)
|
2004-07-27 |
2008-03-21 |
ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング |
D−グルコピラノシル−フェニル置換環状体、そのような化合物を含有する医薬品、それらの使用及びその製造方法
|
WO2006018150A1
(de)
*
|
2004-08-11 |
2006-02-23 |
Boehringer Ingelheim International Gmbh |
D-xylopyranosyl-phenyl-substituierte cyclen, diese verbindungen enthaltende arzneimittel, deren verwendung und verfahren zu ihrer herstellung
|
AR051446A1
(es)
*
|
2004-09-23 |
2007-01-17 |
Bristol Myers Squibb Co |
Glucosidos de c-arilo como inhibidores selectivos de transportadores de glucosa (sglt2)
|
MX2007003785A
(es)
*
|
2004-09-29 |
2007-07-12 |
Kissei Pharmaceutical |
Compuesto heterociclico nitrogenoso 1-(b-d-glicopiranosil)-3, composicion medicinal que contiene el mismo, y uso medicinal del mismo.
|
DE102004048388A1
(de)
|
2004-10-01 |
2006-04-06 |
Boehringer Ingelheim Pharma Gmbh & Co. Kg |
D-Pyranosyl-substituierte Phenyle, diese Verbindungen enthaltende Arzneimittel, deren Verwendung und Verfahren zu ihrer Herstellung
|
WO2006064033A2
(en)
|
2004-12-16 |
2006-06-22 |
Boehringer Ingelheim International Gmbh |
Glucopyranosyl-substituted benzene derivatives, medicaments containing such compounds, their use and process for their manufacture
|
TW200637839A
(en)
*
|
2005-01-07 |
2006-11-01 |
Taisho Pharmaceutical Co Ltd |
1-thio-d-glucitol derivatives
|
ZA200706022B
(en)
*
|
2005-01-28 |
2008-11-26 |
Chugai Pharmaceutical Co Ltd |
Spiroketal derivatives and use thereof as diabetic medicine
|
TW200637869A
(en)
|
2005-01-28 |
2006-11-01 |
Chugai Pharmaceutical Co Ltd |
The spiroketal derivatives and the use as therapeutical agent for diabetes of the same
|
JP4496174B2
(ja)
*
|
2005-01-31 |
2010-07-07 |
田辺三菱製薬株式会社 |
医薬組成物
|
AR053329A1
(es)
*
|
2005-01-31 |
2007-05-02 |
Tanabe Seiyaku Co |
Derivados de indol utiles como inhibidores de los transportadores de glucosa dependientes del sodio (sglt)
|
MY147375A
(en)
|
2005-01-31 |
2012-11-30 |
Mitsubishi Tanabe Pharma Corp |
Indole derivatives
|
ATE421518T1
(de)
*
|
2005-02-10 |
2009-02-15 |
Bristol Myers Squibb Co |
Dihydrochinazolinone als 5ht-modulatoren
|
JP5264183B2
(ja)
*
|
2005-02-23 |
2013-08-14 |
ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング |
グルコピラノシル置換((ヘテロ)アリールエチニル−ベンジル)−ベンゼン誘導体及びナトリウム依存性グルコース共輸送体2(sglt2)インヒビターとしてのそれらの使用
|
WO2006099245A1
(en)
*
|
2005-03-11 |
2006-09-21 |
Elixir Pharmaceuticals, Inc. |
Sirt inhibitors that bind to nad
|
WO2006113261A2
(en)
|
2005-04-14 |
2006-10-26 |
Bristol-Myers Squibb Company |
Inhibitors of 11-beta hydroxysteroid dehydrogenase type i
|
CA2605245A1
(en)
*
|
2005-04-15 |
2006-10-19 |
Boehringer Ingelheim International Gmbh |
Glucopyranosyl-substituted (heteroaryloxy-benzyl)-benzene derivatives as sglt inhibitors
|
UA91546C2
(uk)
|
2005-05-03 |
2010-08-10 |
Бьорінгер Інгельхайм Інтернаціональ Гмбх |
КРИСТАЛІЧНА ФОРМА 1-ХЛОР-4-(β-D-ГЛЮКОПІРАНОЗ-1-ИЛ)-2-[4-((S)-ТЕТРАГІДРОФУРАН-3-ІЛОКСИ)-БЕНЗИЛ]-БЕНЗОЛУ, СПОСІБ ЇЇ ОДЕРЖАННЯ ТА ЇЇ ЗАСТОСУВАННЯ ПРИ ПРИГОТУВАННІ ЛІКАРСЬКИХ ЗАСОБІВ
|
US7723309B2
(en)
*
|
2005-05-03 |
2010-05-25 |
Boehringer Ingelheim International Gmbh |
Crystalline forms of 1-chloro-4-(β-D-glucopyranos-1-yl)-2-[4-((R)-tetrahydrofuran-3-yloxy)-benzyl]-benzene, a method for its preparation and the use thereof for preparing medicaments
|
TW200726746A
(en)
*
|
2005-05-06 |
2007-07-16 |
Microbia Inc |
Processes for production of 4-biphenylylazetidin-2-ones
|
US7772191B2
(en)
|
2005-05-10 |
2010-08-10 |
Boehringer Ingelheim International Gmbh |
Processes for preparing of glucopyranosyl-substituted benzyl-benzene derivatives and intermediates therein
|
WO2007000445A1
(en)
*
|
2005-06-29 |
2007-01-04 |
Boehringer Ingelheim International Gmbh |
Glucopyranosyl-substituted benzyl-benzene derivatives, medicaments containing such compounds, their use and process for their manufacture
|
TW200726755A
(en)
*
|
2005-07-07 |
2007-07-16 |
Astellas Pharma Inc |
A crystalline choline salt of an azulene derivative
|
WO2007011524A1
(en)
*
|
2005-07-14 |
2007-01-25 |
Franco Folli |
Daily dosage regimen for treating diabetes, obsity, metabolic syndrome and polycystic ovary syndrome
|
JP5128474B2
(ja)
*
|
2005-07-27 |
2013-01-23 |
ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング |
グルコピラノシル−置換((ヘテロ)シクロアルキルエチニル−ベンジル)−ベンゼン誘導体、該化合物を含有する薬剤、それらの使用及びそれらの製造方法
|
MX2008000811A
(es)
*
|
2005-07-28 |
2008-03-18 |
Squibb Bristol Myers Co |
Tetrahidro-1h-pitido[4,3-b]indoles substituidos como agonistas y antagonistas del receptor de serotonina.
|
US7795436B2
(en)
*
|
2005-08-24 |
2010-09-14 |
Bristol-Myers Squibb Company |
Substituted tricyclic heterocycles as serotonin receptor agonists and antagonists
|
JP5175191B2
(ja)
*
|
2005-08-30 |
2013-04-03 |
ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング |
グリコピラノシル置換ベンジルベンゼン誘導体、該化合物を含有する医薬品及びその使用と製造方法
|
KR20080053369A
(ko)
|
2005-09-08 |
2008-06-12 |
베링거 인겔하임 인터내셔날 게엠베하 |
1-클로로-4-(β-D-글루코피라노스-1-일)-2-(4-에티닐-벤질)-벤젠의 결정형, 이의 제조 방법 및 약제 제조를 위한이의 용도
|
AR056195A1
(es)
|
2005-09-15 |
2007-09-26 |
Boehringer Ingelheim Int |
Procedimientos para preparar derivados de (etinil-bencil)-benceno sustituidos de glucopiranosilo y compuestos intermedios de los mismos
|
JP2009531291A
(ja)
|
2006-02-15 |
2009-09-03 |
ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング |
グルコピラノシル置換ベンゾニトリル誘導体、それらの化合物を含有する医薬組成物、それらの使用及び製造方法
|
TWI370818B
(en)
*
|
2006-04-05 |
2012-08-21 |
Astellas Pharma Inc |
Cocrystal of c-glycoside derivative and l-proline
|
US20070238770A1
(en)
*
|
2006-04-05 |
2007-10-11 |
Bristol-Myers Squibb Company |
Process for preparing novel crystalline forms of peliglitazar, novel stable forms produced therein and formulations
|
PE20080697A1
(es)
|
2006-05-03 |
2008-08-05 |
Boehringer Ingelheim Int |
Derivados de benzonitrilo sustituidos con glucopiranosilo, composiciones farmaceuticas que contienen compuestos de este tipo, su uso y procedimiento para su fabricacion
|
PE20080251A1
(es)
|
2006-05-04 |
2008-04-25 |
Boehringer Ingelheim Int |
Usos de inhibidores de dpp iv
|
US7973012B2
(en)
*
|
2006-05-19 |
2011-07-05 |
Taisho Pharmaceutical Co., Ltd |
C-phenyl glycitol compound
|
JP5230613B2
(ja)
*
|
2006-05-23 |
2013-07-10 |
テラコス・インコーポレイテッド |
グルコース輸送体阻害剤およびその使用方法
|
DE102006028862A1
(de)
|
2006-06-23 |
2007-12-27 |
Merck Patent Gmbh |
3-Amino-imidazo[1,2-a]pyridinderivate
|
US7919598B2
(en)
|
2006-06-28 |
2011-04-05 |
Bristol-Myers Squibb Company |
Crystal structures of SGLT2 inhibitors and processes for preparing same
|
JP5152519B2
(ja)
|
2006-06-29 |
2013-02-27 |
大正製薬株式会社 |
C−フェニル1−チオグルシト−ル化合物
|
US8318941B2
(en)
|
2006-07-06 |
2012-11-27 |
Bristol-Myers Squibb Company |
Pyridone/hydroxypyridine 11-beta hydroxysteroid dehydrogenase type I inhibitors
|
US7910747B2
(en)
|
2006-07-06 |
2011-03-22 |
Bristol-Myers Squibb Company |
Phosphonate and phosphinate pyrazolylamide glucokinase activators
|
US7795291B2
(en)
|
2006-07-07 |
2010-09-14 |
Bristol-Myers Squibb Company |
Substituted acid derivatives useful as anti-atherosclerotic, anti-dyslipidemic, anti-diabetic and anti-obesity agents and method
|
TWI403516B
(zh)
|
2006-07-27 |
2013-08-01 |
Chugai Pharmaceutical Co Ltd |
To replace spirocyclic alcohol derivatives, and its use as a therapeutic agent for diabetes
|
TWI432446B
(zh)
|
2006-07-27 |
2014-04-01 |
Chugai Pharmaceutical Co Ltd |
稠環螺酮縮醇衍生物、及其做為糖尿病治療藥之使用
|
TWI418556B
(zh)
|
2006-07-27 |
2013-12-11 |
Mitsubishi Tanabe Pharma Corp |
吲哚衍生物
|
CA2656847A1
(en)
*
|
2006-08-15 |
2008-02-21 |
Boehringer Ingelheim International Gmbh |
Glucopyranosyl-substituted cyclopropylbenzene derivatives, pharmaceutical compositions containing such compounds, their use as sglt inhibitors and process for their manufacture
|
US7727978B2
(en)
|
2006-08-24 |
2010-06-01 |
Bristol-Myers Squibb Company |
Cyclic 11-beta hydroxysteroid dehydrogenase type I inhibitors
|
WO2008034859A1
(en)
*
|
2006-09-21 |
2008-03-27 |
Boehringer Ingelheim International Gmbh |
Glucopyranosyl-substituted difluorobenzyl-benzene derivatives, medicaments containing such compounds, their use and process for their manufacture
|
TWI499414B
(zh)
|
2006-09-29 |
2015-09-11 |
Lexicon Pharmaceuticals Inc |
鈉與葡萄糖第2型共同運輸體(co-transporter 2)的抑制物與其應用方法
|
US20100093744A1
(en)
|
2006-10-13 |
2010-04-15 |
Chugai Seiyaku Kabushiki Kaisha |
Thioglucose spiroketal derivative and use thereof as therapeutic agent for diabetes
|
EP2086991A1
(en)
|
2006-10-27 |
2009-08-12 |
Boehringer Ingelheim International GmbH |
CRYSTALLINE FORM OF 4-(ß-D-GLUCOPYRANOS-1-YL)-1-METHYL-2-[4-((S)-TETRAHYDROFURAN-3-YLOXY)-BENZYL]-BENZENE, A METHOD FOR ITS PREPARATION AND THE USE THEREOF FOR PREPARING MEDICAMENTS
|
ES2397664T3
(es)
|
2006-12-04 |
2013-03-08 |
Janssen Pharmaceutica, N.V. |
Derivados de glucopiranósilo que contienen tienilo como antidiabéticos
|
UY30730A1
(es)
|
2006-12-04 |
2008-07-03 |
Mitsubishi Tanabe Pharma Corp |
Forma cristalina del hemihidrato de 1-(b (beta)-d-glucopiranosil) -4-metil-3-[5-(4-fluorofenil) -2-tienilmetil]benceno
|
ATE528300T1
(de)
|
2006-12-06 |
2011-10-15 |
Glaxosmithkline Llc |
Bizyklische verbindungen und ihre verwendung als antidiabetika
|
KR101100072B1
(ko)
|
2006-12-21 |
2011-12-29 |
고토부키 세이야쿠 가부시키가이샤 |
C-글리코시드 유도체의 제조방법 및 이의 합성 중간체
|
US7795228B2
(en)
*
|
2006-12-28 |
2010-09-14 |
Theracos, Inc. |
Spiroheterocyclic glycosides and methods of use
|
DE102007008420A1
(de)
|
2007-02-21 |
2008-08-28 |
Merck Patent Gmbh |
Benzimidazolderivate
|
EP2125768A1
(en)
*
|
2007-02-21 |
2009-12-02 |
Boehringer Ingelheim International GmbH |
Tetrasubstituted glucopyranosylated benzene derivatives, medicaments containing such compounds, their use and process for their manufacture
|
WO2008109591A1
(en)
*
|
2007-03-08 |
2008-09-12 |
Lexicon Pharmaceuticals, Inc. |
Phlorizin analogs as inhibitors of sodium glucose co-transporter 2
|
TW200904405A
(en)
|
2007-03-22 |
2009-02-01 |
Bristol Myers Squibb Co |
Pharmaceutical formulations containing an SGLT2 inhibitor
|
TW200904454A
(en)
|
2007-03-22 |
2009-02-01 |
Bristol Myers Squibb Co |
Methods for treating obesity employing an SGLT2 inhibitor and compositions thereof
|
RU2492175C2
(ru)
*
|
2007-04-02 |
2013-09-10 |
Теракос, Инк. |
Бензиловые производные гликозидов и способы их применения
|
CN101687873A
(zh)
|
2007-04-17 |
2010-03-31 |
百时美施贵宝公司 |
具有稠合杂环的11β-羟基类固醇Ⅰ型脱氢酶抑制剂
|
PE20090696A1
(es)
*
|
2007-04-20 |
2009-06-20 |
Bristol Myers Squibb Co |
Formas cristalinas de saxagliptina y procesos para preparar las mismas
|
WO2008144346A2
(en)
*
|
2007-05-18 |
2008-11-27 |
Bristol-Myers Squibb Company |
Crystal structures of sglt2 inhibitors and processes for their preparation
|
US8969514B2
(en)
|
2007-06-04 |
2015-03-03 |
Synergy Pharmaceuticals, Inc. |
Agonists of guanylate cyclase useful for the treatment of hypercholesterolemia, atherosclerosis, coronary heart disease, gallstone, obesity and other cardiovascular diseases
|
AU2008261102B2
(en)
|
2007-06-04 |
2013-11-28 |
Bausch Health Ireland Limited |
Agonists of guanylate cyclase useful for the treatment of gastrointestinal disorders, inflammation, cancer and other disorders
|
US8383609B2
(en)
|
2007-07-05 |
2013-02-26 |
Centre National De La Recherche Scientifique |
Phosphorus containing heterocyclic compounds, sugar analogues, and compositions having anti-cancer activity containing the same
|
CN103254119B
(zh)
*
|
2007-07-10 |
2016-07-06 |
莱西肯医药有限公司 |
钠-葡萄糖协同转运蛋白2的抑制剂及其用法
|
PL2183263T3
(pl)
|
2007-07-26 |
2012-03-30 |
Lexicon Pharmaceuticals Inc |
Sposoby i związki przydatne do otrzymywania inhibitorów kotransportera 2 sodowo-glukozowego
|
JP2010534722A
(ja)
*
|
2007-07-27 |
2010-11-11 |
ブリストル−マイヤーズ スクイブ カンパニー |
新規グルコキナーゼ活性化薬およびその使用方法
|
CL2008002427A1
(es)
|
2007-08-16 |
2009-09-11 |
Boehringer Ingelheim Int |
Composicion farmaceutica que comprende 1-cloro-4-(b-d-glucopiranos-1-il)-2-[4-((s)-tetrahidrofurano-3-iloxi)bencil]-benceno combinado con 1-[(4-metilquinazolin-2-il)metil]-3-metil-7-(2-butin-1-il)-8-(3-(r)-aminopiperidin-1-il)xantina; y su uso para tratar diabetes mellitus tipo 2.
|
AR068016A1
(es)
*
|
2007-08-23 |
2009-10-28 |
Theracos Inc |
Derivados de bencilbenceno, una composicion farmaceutica que los comprende y su uso en el tratamiento de enfermedades mediadas por sglt
|
ME03072B
(me)
|
2007-09-10 |
2019-01-20 |
Janssen Pharmaceutica Nv |
Postupak za dobijanje jedinjenja која su korisna као inhibiтori sgl т
|
DE102007048716A1
(de)
|
2007-10-11 |
2009-04-23 |
Merck Patent Gmbh |
Imidazo[1,2-a]pyrimidinderivate
|
UA101004C2
(en)
|
2007-12-13 |
2013-02-25 |
Теракос, Инк. |
Derivatives of benzylphenylcyclohexane and use thereof
|
CL2008003653A1
(es)
|
2008-01-17 |
2010-03-05 |
Mitsubishi Tanabe Pharma Corp |
Uso de un inhibidor de sglt derivado de glucopiranosilo y un inhibidor de dppiv seleccionado para tratar la diabetes; y composicion farmaceutica.
|
CN101503399B
(zh)
*
|
2008-02-04 |
2012-06-27 |
白鹭医药技术(上海)有限公司 |
C-芳基葡萄糖苷sglt2抑制剂
|
WO2009117367A1
(en)
*
|
2008-03-18 |
2009-09-24 |
Bristol-Myers Squibb Company |
Method for treating cancers having high glucose requirements employing an sglt2 inhibitor and compositions thereof
|
FR2929615B1
(fr)
|
2008-04-02 |
2010-12-17 |
Tfchem |
Composes c-aryl glycosides pour le traitement du diabete et de l'obesite.
|
DE102008017590A1
(de)
|
2008-04-07 |
2009-10-08 |
Merck Patent Gmbh |
Glucopyranosidderivate
|
US8791077B2
(en)
|
2008-05-22 |
2014-07-29 |
Astrazeneca Ab |
Method for treating hyperuricemia employing an SGLT2 inhibitor and composition containing same
|
JP2011522828A
(ja)
|
2008-06-04 |
2011-08-04 |
シナジー ファーマシューティカルズ インコーポレイテッド |
胃腸障害、炎症、癌、およびその他の障害の治療のために有用なグアニル酸シクラーゼのアゴニスト
|
RU2509773C2
(ru)
*
|
2008-07-15 |
2014-03-20 |
Теракос, Инк. |
Дейтерированные бензилбензольные производные и способы применения
|
WO2010009319A2
(en)
|
2008-07-16 |
2010-01-21 |
Synergy Pharmaceuticals Inc. |
Agonists of guanylate cyclase useful for the treatment of gastrointestinal, inflammation, cancer and other disorders
|
NZ604897A
(en)
|
2008-08-22 |
2014-03-28 |
Theracos Sub Llc |
Processes for the preparation of sglt2 inhibitors
|
CA2733795C
(en)
*
|
2008-08-28 |
2013-12-31 |
Pfizer Inc. |
Dioxa-bicyclo[3.2.1.]octane-2,3,4-triol derivatives
|
US9056850B2
(en)
|
2008-10-17 |
2015-06-16 |
Janssen Pharmaceutica N.V. |
Process for the preparation of compounds useful as inhibitors of SGLT
|
RU2411936C2
(ru)
*
|
2009-01-11 |
2011-02-20 |
Институт физиологии Коми научного центра Уральского отделения Российской академии наук. Государственное учреждение |
Применение 2-морфолино-5-фенил-6н-1,3,4-тиадизин, гидробромида в качестве средства, обладающего гиполипидемическим и гипергликемическим эффектом
|
HUE066463T2
(hu)
*
|
2009-02-13 |
2024-08-28 |
Boehringer Ingelheim Int |
Gyógyszerkészítmény, gyógyszeradagolási forma, eljárás ezek elõállítására, kezelési módszerek és alkalmazásuk
|
KR20110118668A
(ko)
|
2009-02-13 |
2011-10-31 |
베링거 인겔하임 인터내셔날 게엠베하 |
1형 당뇨병, 2형 당뇨병, 내당능 장애 또는 고혈당증을 치료하기 위한 sglt2 억제제
|
UY32427A
(es)
|
2009-02-13 |
2010-09-30 |
Boheringer Ingelheim Internat Gmbh |
Composicion farmaceutica, forma farmaceutica, procedimiento para su preparacion, metodos de tratamiento y usos de la misma
|
ES2797503T3
(es)
|
2009-02-13 |
2020-12-02 |
Boehringer Ingelheim Int |
Composición farmacéutica que comprende un inhibidor de SGLT2, un inhibidor de DPP-IV y opcionalmente un agente antidiabético adicional y sus usos
|
US8563583B2
(en)
|
2009-03-09 |
2013-10-22 |
Bristol-Myers Squibb Company |
Pyridone analogs useful as melanin concentrating hormone receptor-1 antagonists
|
US8278316B2
(en)
|
2009-03-09 |
2012-10-02 |
Bristol-Myers Squibb Company |
Aza pyridone analogs useful as melanin concentrating hormone receptor-1 antagonists
|
US8685934B2
(en)
*
|
2009-05-27 |
2014-04-01 |
Bristol-Myers Squibb Company |
Methods for treating extreme insulin resistance in patients resistant to previous treatment with other anti-diabetic drugs employing an SGLT2 inhibitor and compositions thereof
|
US20110009347A1
(en)
*
|
2009-07-08 |
2011-01-13 |
Yin Liang |
Combination therapy for the treatment of diabetes
|
EP2451797B1
(en)
|
2009-07-10 |
2013-04-03 |
Janssen Pharmaceutica, N.V. |
CRYSTALLISATION PROCESS FOR 1-(ß-D-GLUCOPYRANOSYL)-4-METHYL-3-[5-(4-FLUOROPHENYL)-2-THIENYLMETHYL]BENZENE
|
AU2010303124B2
(en)
|
2009-09-30 |
2014-01-23 |
Boehringer Ingelheim International Gmbh |
Processes for preparing of glucopyranosyl-substituted benzyl-benzene derivatives
|
MX2012002942A
(es)
|
2009-09-30 |
2012-04-11 |
Boehringer Ingelheim Int |
Metodo para la preparacion de una forma cristalina de 1-cloro-4-(beta-d-glucopiranos-1-il)-2-(4-((s)-teteahidrofuran-3- iloxi)bencil)-benceno.
|
US10610489B2
(en)
|
2009-10-02 |
2020-04-07 |
Boehringer Ingelheim International Gmbh |
Pharmaceutical composition, pharmaceutical dosage form, process for their preparation, methods for treating and uses thereof
|
LT2488515T
(lt)
|
2009-10-14 |
2017-03-10 |
Janssen Pharmaceutica Nv |
Junginių, naudotinų kaip sglt2 inhibitorių, paruošimo būdas
|
US8163704B2
(en)
*
|
2009-10-20 |
2012-04-24 |
Novartis Ag |
Glycoside derivatives and uses thereof
|
EP2491050A2
(en)
|
2009-10-20 |
2012-08-29 |
Novartis AG |
Glycoside derivative and uses thereof
|
DK2496583T3
(en)
|
2009-11-02 |
2015-02-02 |
Pfizer |
Dioxa-bicyclo [3.2.1] octane-2,3,4-triol DERIVATIVES
|
PT2498759T
(pt)
|
2009-11-13 |
2018-11-15 |
Astrazeneca Uk Ltd |
Formulações de comprimidos de libertação imediata
|
AR079438A1
(es)
*
|
2009-12-09 |
2012-01-25 |
Panacea Biotec Ltd |
Derivados de azucar, composiciones farmaceuticas y sus usos
|
TWI562775B
(en)
|
2010-03-02 |
2016-12-21 |
Lexicon Pharmaceuticals Inc |
Methods of using inhibitors of sodium-glucose cotransporters 1 and 2
|
WO2011107494A1
(de)
|
2010-03-03 |
2011-09-09 |
Sanofi |
Neue aromatische glykosidderivate, diese verbindungen enthaltende arzneimittel und deren verwendung
|
JP2013523681A
(ja)
|
2010-03-30 |
2013-06-17 |
ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング |
Sglt2インヒビター及びppar−ガンマアゴニストを含む医薬組成物並びにその使用
|
US8592396B2
(en)
|
2010-04-14 |
2013-11-26 |
Bristol-Myers Squibb Company |
Glucokinase activators and methods of using same
|
ME02531B
(me)
|
2010-05-11 |
2017-02-20 |
Janssen Pharmaceutica Nv |
FARMACEUTSKE FORMULACilE KOJE OBUHVATAJU DERIVATIVE 1 - (BE TA- D- GLUKOPIRANOZ IL)-2- TIENILMETILBENZENA KAO SGLT INHIBITORE
|
WO2011153712A1
(en)
*
|
2010-06-12 |
2011-12-15 |
Theracos, Inc. |
Crystalline form of benzylbenzene sglt2 inhibitor
|
WO2012025857A1
(en)
|
2010-08-23 |
2012-03-01 |
Hetero Research Foundation |
Cycloalkyl methoxybenzyl phenyl pyran derivatives as sodium dependent glucose co transporter (sglt2) inhibitors
|
KR20130137624A
(ko)
|
2010-09-03 |
2013-12-17 |
브리스톨-마이어스 스큅 컴퍼니 |
수용성 항산화제를 사용한 약물 제제
|
US9616097B2
(en)
|
2010-09-15 |
2017-04-11 |
Synergy Pharmaceuticals, Inc. |
Formulations of guanylate cyclase C agonists and methods of use
|
WO2012041898A1
(en)
|
2010-09-29 |
2012-04-05 |
Celon Pharma Sp. Z O.O. |
Combination of sglt2 inhibitor and a sugar compound for the treatment of diabetes
|
CN102453026A
(zh)
|
2010-10-27 |
2012-05-16 |
上海艾力斯医药科技有限公司 |
C-芳基葡糖苷衍生物、制备方法及其应用
|
US20120283169A1
(en)
|
2010-11-08 |
2012-11-08 |
Boehringer Ingelheim International Gmbh |
Pharmaceutical composition, methods for treating and uses thereof
|
TWI631963B
(zh)
|
2011-01-05 |
2018-08-11 |
雷西肯製藥股份有限公司 |
包含鈉-葡萄糖共同輸送體1與2之抑制劑的組合物與應用方法
|
RU2607480C2
(ru)
|
2011-02-01 |
2017-01-10 |
Бристол-Майерс Сквибб Компани |
Фармацевтические композиции, содержащие аминосоединение
|
US20130035281A1
(en)
|
2011-02-09 |
2013-02-07 |
Boehringer Ingelheim International Gmbh |
Pharmaceutical composition, methods for treating and uses thereof
|
CN102643256B
(zh)
|
2011-02-18 |
2014-12-24 |
上海璎黎科技有限公司 |
一种芳基糖苷类化合物及其制备方法和应用
|
AR085689A1
(es)
|
2011-03-07 |
2013-10-23 |
Boehringer Ingelheim Int |
Composiciones farmaceuticas de metformina, linagliptina y un inhibidor de sglt-2
|
CN102675378A
(zh)
*
|
2011-03-09 |
2012-09-19 |
天津药物研究院 |
一类含环丙烷结构的c-葡萄糖苷衍生物、其制备方法和用途
|
US9346852B2
(en)
|
2011-03-14 |
2016-05-24 |
Bristol-Myers Scuibb Company |
Substituted adipic acid amides and uses thereof
|
CA2832938C
(en)
|
2011-04-13 |
2019-09-03 |
Janssen Pharmaceutica Nv |
Process for the preparation of compounds useful as inhibitors of sglt2
|
EA201391524A1
(ru)
|
2011-04-14 |
2014-04-30 |
Новартис Аг |
Производные гликозида и их применение
|
US8614195B2
(en)
|
2011-04-14 |
2013-12-24 |
Novartis Ag |
Glycoside derivatives and uses thereof
|
TWI542596B
(zh)
|
2011-05-09 |
2016-07-21 |
健生藥品公司 |
(2s,3r,4r,5s,6r)-2-(3-((5-(4-氟苯基)噻吩-2-基)甲基)-4-甲基苯基)-6-(羥甲基)四氫-2h-哌喃-3,4,5-三醇之l-脯胺酸及檸檬酸共晶體
|
TR201903445T4
(tr)
*
|
2011-06-01 |
2019-03-21 |
Green Cross Corp |
Sglt2 i̇nhi̇bi̇törleri̇ olarak yeni̇ di̇feni̇lmetan türevleri̇
|
BR112013031032A2
(pt)
|
2011-06-03 |
2016-11-29 |
Boehringer Ingelheim Int |
inibidores de sglt-2 para o tratamento de distúrbios metabólicos em pacientes tratados com agentes neurolépticos
|
AR086922A1
(es)
*
|
2011-06-13 |
2014-01-29 |
Panacea Biotec Ltd |
Derivados de 3,4,5-trihidroxi-6-(hidroximetil)tetrahidro-2h-pirano utiles para el tratamiento de diabetes y dislipidemias, composiciones farmaceuticas que los contienen y metodo para prepararlos
|
CN102827122B
(zh)
*
|
2011-06-17 |
2015-01-14 |
山东轩竹医药科技有限公司 |
糖苷衍生物
|
EP2725031B1
(en)
|
2011-06-25 |
2016-08-03 |
Xuanzhu Pharma Co., Ltd. |
C-glycoside derivatives
|
US20130035298A1
(en)
|
2011-07-08 |
2013-02-07 |
Boehringer Ingelheim International Gmbh |
Pharmaceutical composition, methods for treating and uses thereof
|
US8710049B2
(en)
|
2011-07-18 |
2014-04-29 |
Bristol-Myers Squibb Company |
Diaminocyclohexane compounds and uses thereof
|
US8815909B2
(en)
|
2011-07-18 |
2014-08-26 |
Bristol-Myers Squibb Company |
Diaminocyclohexane compounds and uses thereof
|
WO2013038429A2
(en)
|
2011-09-13 |
2013-03-21 |
Panacea Biotec Ltd. |
Novel sglt inhibitors
|
US9555001B2
(en)
|
2012-03-07 |
2017-01-31 |
Boehringer Ingelheim International Gmbh |
Pharmaceutical composition and uses thereof
|
US9192617B2
(en)
|
2012-03-20 |
2015-11-24 |
Boehringer Ingelheim International Gmbh |
Pharmaceutical composition, methods for treating and uses thereof
|
US9193751B2
(en)
|
2012-04-10 |
2015-11-24 |
Theracos, Inc. |
Process for the preparation of benzylbenzene SGLT2 inhibitors
|
WO2013178064A1
(zh)
*
|
2012-05-29 |
2013-12-05 |
广东东阳光药业有限公司 |
吡喃葡萄糖基衍生物、其制备方法及其在医药上的应用
|
CA2883118A1
(en)
*
|
2012-08-30 |
2014-03-06 |
Taisho Pharmaceutical Co., Ltd. |
Combinations of sglt 2 inhibitors and antihypertensive drugs
|
WO2014039412A1
(en)
|
2012-09-05 |
2014-03-13 |
Bristol-Myers Squibb Company |
Pyrrolone or pyrrolidinone melanin concentrating hormone receptor-1 antagonists
|
WO2014039411A1
(en)
|
2012-09-05 |
2014-03-13 |
Bristol-Myers Squibb Company |
Pyrrolone or pyrrolidinone melanin concentrating hormore receptor-1 antagonists
|
CN103910769B
(zh)
|
2012-12-31 |
2018-10-02 |
上海璎黎药业有限公司 |
葡萄糖衍生物和脯氨酸的复合物、晶体、制备方法及应用
|
EP2774619B1
(de)
|
2013-03-04 |
2016-05-18 |
BioActive Food GmbH |
Zusammensetzung zur Behandlung von hyperglykämischen Erkrankungen
|
US8652527B1
(en)
|
2013-03-13 |
2014-02-18 |
Upsher-Smith Laboratories, Inc |
Extended-release topiramate capsules
|
US9573959B2
(en)
|
2013-03-14 |
2017-02-21 |
Msd International Gmbh |
Methods for preparing SGLT2 inhibitors
|
US9101545B2
(en)
|
2013-03-15 |
2015-08-11 |
Upsher-Smith Laboratories, Inc. |
Extended-release topiramate capsules
|
EP2970384A1
(en)
|
2013-03-15 |
2016-01-20 |
Synergy Pharmaceuticals Inc. |
Agonists of guanylate cyclase and their uses
|
HK1220611A1
(zh)
|
2013-03-15 |
2017-05-12 |
Bausch Health Ireland Limited |
用於治療胃腸道病症的組成物
|
CN104059042B
(zh)
*
|
2013-03-22 |
2017-02-08 |
正大天晴药业集团股份有限公司 |
C-三芳基葡萄糖苷类sglt-2抑制剂
|
WO2014161836A1
(en)
|
2013-04-04 |
2014-10-09 |
Boehringer Ingelheim Vetmedica Gmbh |
Treatment of metabolic disorders in equine animals
|
HRP20190101T1
(hr)
|
2013-04-05 |
2019-03-08 |
Boehringer Ingelheim International Gmbh |
Terapeutske uporabe empagliflozina
|
US11813275B2
(en)
|
2013-04-05 |
2023-11-14 |
Boehringer Ingelheim International Gmbh |
Pharmaceutical composition, methods for treating and uses thereof
|
US20140303097A1
(en)
|
2013-04-05 |
2014-10-09 |
Boehringer Ingelheim International Gmbh |
Pharmaceutical composition, methods for treating and uses thereof
|
HRP20220365T1
(hr)
|
2013-04-18 |
2022-05-13 |
Boehringer Ingelheim International Gmbh |
Farmaceutski pripravak, postupci za liječenje i njegove uporabe
|
WO2014178040A1
(en)
|
2013-04-29 |
2014-11-06 |
Mapi Pharma Ltd. |
Co-crystals of dapagliflozin
|
CN113388007A
(zh)
|
2013-06-05 |
2021-09-14 |
博士医疗爱尔兰有限公司 |
鸟苷酸环化酶c的超纯激动剂、制备和使用所述激动剂的方法
|
WO2015032272A1
(zh)
*
|
2013-09-09 |
2015-03-12 |
江苏豪森药业股份有限公司 |
C-芳基葡糖苷衍生物、其制备方法及其在医药上的应用
|
JP6450769B2
(ja)
|
2013-09-27 |
2019-01-09 |
サンシャイン・レイク・ファーマ・カンパニー・リミテッドSunshine Lake Pharma Co.,Ltd. |
グルコピラノシル誘導体及びその医薬品における使用
|
CN105611920B
(zh)
*
|
2013-10-12 |
2021-07-16 |
泰拉科斯萨普有限责任公司 |
羟基-二苯甲烷衍生物的制备
|
SI3862003T1
(sl)
|
2013-12-17 |
2024-02-29 |
Boehringer Ingelheim Vetmedica Gmbh |
Inhibitor SGLT-2 za uporabo pri zdravljenju metabolične motnje pri mačjih živalih
|
US9902751B2
(en)
|
2013-12-30 |
2018-02-27 |
Mylan Laboratories Limited |
Process for the preparation of empagliflozin
|
EP2891654B1
(en)
|
2014-01-03 |
2016-06-22 |
Xuanzhu Pharma Co., Ltd. |
Optically pure benzyl-4-chlorophenyl-C-glucoside derivatives as SGLT inhibitors (diabetes mellitus)
|
US9315438B2
(en)
|
2014-01-03 |
2016-04-19 |
Xuanzhu Pharma Co., Ltd |
Optically pure benzyl-4-chlorophenyl-C-glucoside derivative
|
DK3485890T3
(da)
*
|
2014-01-23 |
2023-08-21 |
Boehringer Ingelheim Vetmedica Gmbh |
Sglt2-hæmmere til behandling af stofskifteforstyrrelser hos hundedyr
|
WO2015132803A2
(en)
*
|
2014-03-06 |
2015-09-11 |
Msn Laboratories Private Limited |
Process for the preparation of (1s)-1,5-anhydro-1-c-[4-chloro-3-[(4-ethoxyphenyl)methyl]phenyl]-d-glucitol and its solvate thereof
|
EP4454653A3
(en)
|
2014-04-01 |
2025-01-22 |
Boehringer Ingelheim Vetmedica GmbH |
Treatment of pituitary pars intermedia dysfunction in equine animals
|
CN105001213B
(zh)
*
|
2014-04-14 |
2020-08-28 |
上海迪诺医药科技有限公司 |
C-芳基糖苷衍生物、其药物组合物、制备方法及应用
|
TW201623321A
(zh)
|
2014-05-13 |
2016-07-01 |
韓美藥品股份有限公司 |
雙環衍生物及包含其之藥學組成物
|
EP2944311A1
(de)
|
2014-05-16 |
2015-11-18 |
BioActive Food GmbH |
Kombination von biologisch aktiven Substanzen zur Behandlung von hyperglykämischen Erkrankungen
|
CN105085494B
(zh)
*
|
2014-05-22 |
2019-07-02 |
中国医学科学院药物研究所 |
钠糖共转运体2抑制剂、其制法和其药物组合物与用途
|
CA2961148A1
(en)
|
2014-09-25 |
2016-03-31 |
Astrazeneca Ab |
Use of a combination of an omega-3 fatty acid and an sglt-2 inhibitor for the treatment of non-alcoholic liver disease
|
HUE068152T2
(hu)
|
2014-09-25 |
2024-12-28 |
Boehringer Ingelheim Vetmedica Gmbh |
SGLT2-gátlók és dopamin agonisták kombinációs kezelése anyagcserezavarok megelõzésére lófélékben
|
CN104327027B
(zh)
*
|
2014-10-14 |
2017-04-05 |
中国药科大学 |
一类新型c‑芳基葡萄糖苷sglt2抑制剂
|
EP3256482B1
(en)
*
|
2015-02-09 |
2019-11-27 |
Indoco Remedies Limited |
Process for the preparation of sglt inhibitor compounds
|
JP2018507914A
(ja)
|
2015-03-09 |
2018-03-22 |
インテクリン・セラピューティクス・インコーポレイテッド |
非アルコール性脂肪肝疾患および/またはリポジストロフィーの処置のための方法
|
WO2016161995A1
(en)
|
2015-04-08 |
2016-10-13 |
Zentiva, K.S. |
Solid forms of amorphous dapagliflozin
|
CN106317068A
(zh)
*
|
2015-06-23 |
2017-01-11 |
中国科学院上海药物研究所 |
一种c,o-螺环芳基糖苷类化合物及其制备和应用
|
FI3341024T3
(fi)
|
2015-08-27 |
2024-12-18 |
Boehringer Ingelheim Vetmedica Gmbh |
Sglt-2-estäjiä käsittäviä nestemäisiä farmaseuttisia koostumuksia
|
US20170071970A1
(en)
|
2015-09-15 |
2017-03-16 |
Janssen Pharmaceutica Nv |
Co-therapy comprising canagliflozin and phentermine for the treatment of obesity and obesity related disorders
|
US20170106009A1
(en)
|
2015-10-15 |
2017-04-20 |
Boehringer Ingelheim International Gmbh |
Methods of treating diseases
|
KR102004488B1
(ko)
|
2015-12-11 |
2019-07-26 |
동아에스티 주식회사 |
다파글리플로진의 신규 용매화물 및 이의 제조방법
|
CN106892929B
(zh)
*
|
2015-12-17 |
2020-01-14 |
上海艾力斯医药科技有限公司 |
螺缩酮衍生物及其制备方法和应用
|
CN105693669A
(zh)
*
|
2015-12-28 |
2016-06-22 |
南昌大学 |
一种抗糖尿病化合物及其制备方法和用途
|
NZ743987A
(en)
|
2016-01-04 |
2019-10-25 |
Je Il Pharmaceutical Co Ltd |
C-glucoside derivative containing fused phenyl ring or pharmaceutically acceptable salt thereof, process for preparing same, and pharmaceutical composition comprising same
|
WO2017141202A1
(en)
|
2016-02-17 |
2017-08-24 |
Lupin Limited |
Complex of sglt2 inhibitor and process for preparation thereof
|
US9834533B2
(en)
*
|
2016-02-19 |
2017-12-05 |
Scinopharm Taiwan, Ltd. |
Process for preparing SGLT2 inhibitors and intermediates thereof
|
WO2017221211A1
(en)
*
|
2016-06-24 |
2017-12-28 |
Biocon Limited |
Process for the preparation of dapagliflozin and its solvate thereof
|
WO2018002673A1
(en)
|
2016-07-01 |
2018-01-04 |
N4 Pharma Uk Limited |
Novel formulations of angiotensin ii receptor antagonists
|
WO2018073154A1
(en)
|
2016-10-19 |
2018-04-26 |
Boehringer Ingelheim International Gmbh |
Combinations comprising an ssao/vap-1 inhibitor and a sglt2 inhibitor, uses thereof
|
WO2018087132A1
(en)
|
2016-11-10 |
2018-05-17 |
Boehringer Ingelheim International Gmbh |
Pharmaceutical composition, methods for treating and uses thereof
|
US11020412B2
(en)
|
2017-03-16 |
2021-06-01 |
Inventia Healthcare Limited |
Pharmaceutical composition comprising dapagliflozin
|
CN110996951A
(zh)
|
2017-04-03 |
2020-04-10 |
科赫罗斯生物科学股份有限公司 |
治疗进行性核上性麻痹的PPARγ激动剂
|
KR101943382B1
(ko)
*
|
2017-09-19 |
2019-01-29 |
오토텔릭바이오 주식회사 |
Sglt-2 저해제 및 안지오텐신 수용체 차단제를 포함하는 의약 조성물
|
EP3781166A1
(en)
|
2018-04-17 |
2021-02-24 |
Boehringer Ingelheim International GmbH |
Pharmaceutical composition, methods for treating and uses thereof
|
KR102204439B1
(ko)
|
2018-05-14 |
2021-01-18 |
에이치케이이노엔 주식회사 |
Sglt-2 억제제 및 dpp-iv 억제제를 포함하는 약제학적 조성물
|
KR20200022257A
(ko)
*
|
2018-08-22 |
2020-03-03 |
동아에스티 주식회사 |
Sglt-2 억제제인 다파글리플로진 전구체의 제조방법
|
WO2020039394A1
(en)
|
2018-08-24 |
2020-02-27 |
Novartis Ag |
New drug combinations
|
US12213970B2
(en)
|
2018-10-29 |
2025-02-04 |
Boehringer Ingelheim International Gmbh |
Pyridinyl sulfonamide derivatives, pharmaceutical compositions and uses thereof
|
HUE064995T2
(hu)
|
2018-10-29 |
2024-04-28 |
Boehringer Ingelheim Int |
Piridinil-szulfonamid-származékok, gyógyszerkészítmények és azok felhasználása
|
CN111471032B
(zh)
*
|
2019-01-24 |
2023-08-01 |
北京盈科瑞创新药物研究有限公司 |
一种糖苷类衍生物的合成方法及其中间体和应用
|
CN111471040B
(zh)
*
|
2019-01-24 |
2023-06-02 |
北京盈科瑞创新药物研究有限公司 |
一种糖苷类衍生物的合成方法及其中间体和应用
|
WO2020151621A1
(zh)
*
|
2019-01-24 |
2020-07-30 |
北京盈科瑞创新药物研究有限公司 |
化合物、其制备方法及医药用途
|
CN111471031B
(zh)
*
|
2019-01-24 |
2023-05-16 |
北京盈科瑞创新药物研究有限公司 |
一种糖苷类衍生物及其制备方法和应用
|
CN111840271B
(zh)
*
|
2019-04-25 |
2024-05-14 |
北京盈科瑞创新药物研究有限公司 |
一种糖苷类衍生物新用途
|
CA3079175A1
(en)
|
2019-08-30 |
2021-02-28 |
Astrazeneca Ab |
Methods of treating heart failure with reduced ejection fraction with dapagliflozin
|
MX2022006490A
(es)
|
2019-11-28 |
2022-07-04 |
Boehringer Ingelheim Vetmedica Gmbh |
Uso de inhibidores de sglt-2 en el secado de mamiferos no humanos.
|
RS65877B1
(sr)
|
2020-02-07 |
2024-09-30 |
Gasherbrum Bio Inc |
Heterociklični agonisti glp-1
|
CA3167531A1
(en)
|
2020-02-17 |
2021-08-26 |
Boehringer Ingelheim Vetmedica Gmbh |
Use of sglt-2 inhibitors for the prevention and/or treatment of cardiac diseases in felines
|
EP4114365A1
(en)
|
2020-03-05 |
2023-01-11 |
KRKA, d.d., Novo mesto |
Pharmaceutical composition comprising sglt2 inhibitor
|
BR112022017189A2
(pt)
|
2020-03-06 |
2022-10-18 |
Vertex Pharma |
Métodos de tratamento de glomeruloesclerose segmentar focal dependente de apol-1
|
US20230201174A1
(en)
|
2020-04-22 |
2023-06-29 |
Bayer Aktiengesellschaft |
Combination of finerenone and a sglt2 inhibitor for the treatment and/or prevention of cardiovascular and/or renal diseases
|
US20230165856A1
(en)
|
2020-04-29 |
2023-06-01 |
Astrazeneca Ab |
Dapagliflozin and ambrisentan for the prevention and treatment of covid-19
|
EP4161912A1
(en)
|
2020-06-05 |
2023-04-12 |
KRKA, d.d., Novo mesto |
Preparation of highly pure amorphous dapagliflozin
|
TW202220672A
(zh)
|
2020-07-27 |
2022-06-01 |
瑞典商阿斯特捷利康公司 |
用達格列淨治療慢性腎臟病之方法
|
PE20231181A1
(es)
|
2020-08-06 |
2023-08-11 |
Gasherbrum Bio Inc |
Agonistas del glp-1 heterociclicos
|
WO2022051316A1
(en)
|
2020-09-03 |
2022-03-10 |
Coherus Biosciences, Inc. |
Fixed dose combinations of chs-131 and a sglt-2 inhibitor
|
CN114539231B
(zh)
*
|
2020-11-19 |
2023-11-21 |
北京盈科瑞创新药物研究有限公司 |
一种糖苷类衍生物及其制备方法和应用
|
KR20220091233A
(ko)
|
2020-12-23 |
2022-06-30 |
(주)국전약품 |
다파글리플로진 전구약물, 이의 제조방법 및 이를 포함하는 약제학적 조성물
|
AU2022251165A1
(en)
|
2021-04-01 |
2023-11-09 |
Astrazeneca Uk Limited |
Systems and methods for managing prediabetes with a gliflozin sodium-glucose cotransport 2 inhibitor pharmaceutical composition
|
EP4376819A1
(en)
|
2021-07-28 |
2024-06-05 |
Boehringer Ingelheim Vetmedica GmbH |
Use of sglt-2 inhibitors for the prevention and/or treatment of hypertension in non-human mammals
|
EP4376829A1
(en)
|
2021-07-28 |
2024-06-05 |
Boehringer Ingelheim Vetmedica GmbH |
Use of sglt-2 inhibitors for the prevention and/or treatment of cardiac diseases in non-human mammals excluding felines, in particular canines
|
JP2024525981A
(ja)
|
2021-07-28 |
2024-07-12 |
ベーリンガー インゲルハイム フェトメディカ ゲーエムベーハー |
ヒト以外の哺乳動物における腎疾患の予防及び/又は治療のためのsglt-2阻害剤の使用
|
JP2025503136A
(ja)
|
2022-01-26 |
2025-01-30 |
アストラゼネカ・アクチエボラーグ |
前糖尿病の治療又は2型糖尿病の発症リスクを低減する際に使用するためのダパグリフロジン
|
CN119137124A
(zh)
|
2022-03-09 |
2024-12-13 |
加舒布鲁姆生物公司 |
杂环glp-1激动剂
|
US20250206757A1
(en)
|
2022-03-21 |
2025-06-26 |
Gasherbrum Bio, Inc. |
5,8-dihydro-1,7-naphthyridine derivatives as glp-1 agonists for the treatment of diabetes
|
JP2025513071A
(ja)
|
2022-04-14 |
2025-04-22 |
ガシャーブラム・バイオ・インコーポレイテッド |
ヘテロ環式glp-1アゴニスト
|
EP4531810A1
(en)
|
2022-05-25 |
2025-04-09 |
Boehringer Ingelheim Vetmedica GmbH |
Aqueous pharmaceutical compositions comprising sglt-2 inhibitors
|
WO2024033288A1
(en)
*
|
2022-08-12 |
2024-02-15 |
Société des Produits Nestlé S.A. |
Salicin derivatives as inhibitors of sglt2
|
US20240307628A1
(en)
|
2023-03-06 |
2024-09-19 |
Boehringer Ingelheim Vetmedica Gmbh |
Systems and methods for delivery of liquid pharmaceutical compositions in particular comprising one or more sglt-2 inhibitor(s)
|
US20240390332A1
(en)
|
2023-05-24 |
2024-11-28 |
Boehringer Ingelheim Vetmedica Gmbh |
Combination treatment and/or prevention of renal diseases and/or hypertension in non-human mammals comprising one or more SGLT-2 inhibitors and telmisartan
|
WO2024240632A1
(en)
|
2023-05-24 |
2024-11-28 |
Boehringer Ingelheim Vetmedica Gmbh |
Combination treatment and/or prevention of cardiac diseases in non-human mammals comprising one or more sglt-2 inhibitors and pimobendan and/or telmisartan
|
WO2025125513A1
(en)
|
2023-12-15 |
2025-06-19 |
AstraZeneca Ireland Limited |
Sglt2 inhibitors and baxdrostat for treating chronic kidney disease and hypertension
|