US3126375A
(en)
|
|
1964-03-24 |
|
Chioacyl |
US2789118A
(en)
|
1956-03-30 |
1957-04-16 |
American Cyanamid Co |
16-alpha oxy-belta1, 4-pregnadienes
|
US2990401A
(en)
|
1958-06-18 |
1961-06-27 |
American Cyanamid Co |
11-substituted 16alpha, 17alpha-substituted methylenedioxy steroids
|
US3048581A
(en)
|
1960-04-25 |
1962-08-07 |
Olin Mathieson |
Acetals and ketals of 16, 17-dihydroxy steroids
|
US3749712A
(en)
|
1970-09-25 |
1973-07-31 |
Sigma Tau Ind Farmaceuti |
Triamcinolone acetonide esters and process for their preparation
|
US3996359A
(en)
|
1972-05-19 |
1976-12-07 |
Ab Bofors |
Novel stereoisomeric component A of stereoisomeric mixtures of 2'-unsymmetrical 16,17-methylenedioxy steroid 21-acylates, compositions thereof, and method of treating therewith
|
SE378110B
(US06815460-20041109-C00097.png)
|
1972-05-19 |
1975-08-18 |
Bofors Ab |
|
SE378109B
(US06815460-20041109-C00097.png)
|
1972-05-19 |
1975-08-18 |
Bofors Ab |
|
US4294926A
(en)
|
1979-06-15 |
1981-10-13 |
Merck & Co., Inc. |
Hypocholesteremic fermentation products and process of preparation
|
US4319039A
(en)
|
1979-06-15 |
1982-03-09 |
Merck & Co., Inc. |
Preparation of ammonium salt of hypocholesteremic fermentation product
|
US4231938A
(en)
|
1979-06-15 |
1980-11-04 |
Merck & Co., Inc. |
Hypocholesteremic fermentation products and process of preparation
|
US4444784A
(en)
|
1980-08-05 |
1984-04-24 |
Merck & Co., Inc. |
Antihypercholesterolemic compounds
|
MX7065E
(es)
|
1980-06-06 |
1987-04-10 |
Sankyo Co |
Un procedimiento microbiologico para preparar derivados de ml-236b
|
JPS5889191A
(ja)
|
1981-11-20 |
1983-05-27 |
Sankyo Co Ltd |
3−ヒドロキシ−ml−236b誘導体の製造法
|
US5354772A
(en)
|
1982-11-22 |
1994-10-11 |
Sandoz Pharm. Corp. |
Indole analogs of mevalonolactone and derivatives thereof
|
US4911165A
(en)
|
1983-01-12 |
1990-03-27 |
Ethicon, Inc. |
Pliabilized polypropylene surgical filaments
|
US4681893A
(en)
|
1986-05-30 |
1987-07-21 |
Warner-Lambert Company |
Trans-6-[2-(3- or 4-carboxamido-substituted pyrrol-1-yl)alkyl]-4-hydroxypyran-2-one inhibitors of cholesterol synthesis
|
US4885314A
(en)
|
1987-06-29 |
1989-12-05 |
Merck & Co., Inc. |
Novel HMG-CoA reductase inhibitors
|
US4782084A
(en)
|
1987-06-29 |
1988-11-01 |
Merck & Co., Inc. |
HMG-COA reductase inhibitors
|
US4820850A
(en)
|
1987-07-10 |
1989-04-11 |
Merck & Co., Inc. |
Process for α-C-alkylation of the 8-acyl group on mevinolin and analogs thereof
|
US5030447A
(en)
|
1988-03-31 |
1991-07-09 |
E. R. Squibb & Sons, Inc. |
Pharmaceutical compositions having good stability
|
US5180589A
(en)
|
1988-03-31 |
1993-01-19 |
E. R. Squibb & Sons, Inc. |
Pravastatin pharmaceuatical compositions having good stability
|
US4916239A
(en)
|
1988-07-19 |
1990-04-10 |
Merck & Co., Inc. |
Process for the lactonization of mevinic acids and analogs thereof
|
EP0360390A1
(en)
|
1988-07-25 |
1990-03-28 |
Glaxo Group Limited |
Spirolactam derivatives
|
US5118853A
(en)
|
1988-10-13 |
1992-06-02 |
Sandoz Ltd. |
Processes for the synthesis of 3-disubstituted aminoacroleins
|
US5290946A
(en)
|
1988-10-13 |
1994-03-01 |
Sandoz Ltd. |
Processes for the synthesis of 3-(substituted indolyl-2-yl)propenaldehydes
|
MX18467A
(es)
|
1988-11-23 |
1993-07-01 |
Pfizer |
Agentes terapeuticos de quinuclidinas
|
US4929437A
(en)
|
1989-02-02 |
1990-05-29 |
Merck & Co., Inc. |
Coenzyme Q10 with HMG-CoA reductase inhibitors
|
US5164372A
(en)
|
1989-04-28 |
1992-11-17 |
Fujisawa Pharmaceutical Company, Ltd. |
Peptide compounds having substance p antagonism, processes for preparation thereof and pharmaceutical composition comprising the same
|
US5189164A
(en)
|
1989-05-22 |
1993-02-23 |
Sandoz Ltd. |
Processes for the synthesis of syn-(E)-3,5-dihydroxy-7-substituted hept-6-enoic and heptanoic acids and derivatives and intermediates thereof
|
FI94339C
(fi)
|
1989-07-21 |
1995-08-25 |
Warner Lambert Co |
Menetelmä farmaseuttisesti käyttökelpoisen /R-(R*,R*)/-2-(4-fluorifenyyli)- , -dihydroksi-5-(1-metyylietyyli)-3-fenyyli-4-/(fenyyliamino)karbonyyli/-1H-pyrroli-1-heptaanihapon ja sen farmaseuttisesti hyväksyttävien suolojen valmistamiseksi
|
PH27357A
(en)
|
1989-09-22 |
1993-06-21 |
Fujisawa Pharmaceutical Co |
Pyrazole derivatives and pharmaceutical compositions comprising the same
|
IE903957A1
(en)
|
1989-11-06 |
1991-05-08 |
Sanofi Sa |
Aromatic amine compounds, their method of preparation and¹pharmaceutical compositions in which they are present
|
FR2654725B1
(fr)
|
1989-11-23 |
1992-02-14 |
Rhone Poulenc Sante |
Nouveaux derives de l'isoindolone, leur preparation et les compositions pharmaceutiques qui les contiennent.
|
FR2654726B1
(fr)
|
1989-11-23 |
1992-02-14 |
Rhone Poulenc Sante |
Nouveaux derives de l'isoindolone et leur preparation.
|
GB8929070D0
(en)
|
1989-12-22 |
1990-02-28 |
Fujisawa Pharmaceutical Co |
Peptide compounds,processes for preparation thereof and pharmaceutical composition comprising the same
|
US5232929A
(en)
|
1990-11-28 |
1993-08-03 |
Pfizer Inc. |
3-aminopiperidine derivatives and related nitrogen containing heterocycles and pharmaceutical compositions and use
|
UA41251C2
(uk)
|
1990-01-04 |
2001-09-17 |
Пфайзер, Інк. |
Гідровані азотвмісні гетероциклічні сполуки, похідні піперидину, фармацевтична композиція та спосіб пригнічення активності речовини р в організмі
|
US5321032A
(en)
|
1990-02-15 |
1994-06-14 |
Fujisawa Pharmaceutical Co., Ltd. |
Peptide compounds and pharmaceutical compositions thereof
|
US5420245A
(en)
|
1990-04-18 |
1995-05-30 |
Board Of Regents, The University Of Texas |
Tetrapeptide-based inhibitors of farnesyl transferase
|
AU648317B2
(en)
|
1990-06-01 |
1994-04-21 |
Pfizer Inc. |
3-amino-2-aryl quinuclidines, process for their preparation and pharmaceutical compositions containing them
|
HUT62584A
(en)
|
1990-07-23 |
1993-05-28 |
Pfizer |
Process for producing quinuclidine derivatives
|
JPH0772175B2
(ja)
|
1990-09-28 |
1995-08-02 |
フアイザー・インコーポレイテツド |
窒素含有非芳香族複素環の縮合環類似体
|
GB9023116D0
(en)
|
1990-10-24 |
1990-12-05 |
Fujisawa Pharmaceutical Co |
Peptide compounds,processes for preparation thereof and pharmaceutical composition comprising the same
|
EP0498069B1
(en)
|
1990-12-21 |
1995-10-25 |
Fujisawa Pharmaceutical Co., Ltd. |
New use of peptide derivative
|
CA2100163A1
(en)
|
1991-01-10 |
1992-07-11 |
John A. Lowe, Iii |
N-alkyl quinuclidinium salts
|
US5242930A
(en)
|
1991-02-11 |
1993-09-07 |
Merck Sharp & Dohme Ltd. |
Azabicyclic compounds, pharmaceutical compositions containing them and their use in therapy
|
JPH082901B2
(ja)
|
1991-03-01 |
1996-01-17 |
ファイザー・インコーポレーテッド |
1−アザビシクロ[3.2.2ノナン−3−アミン誘導体類
|
US5747469A
(en)
|
1991-03-06 |
1998-05-05 |
Board Of Regents, The University Of Texas System |
Methods and compositions comprising DNA damaging agents and p53
|
JPH0794440B2
(ja)
|
1991-03-26 |
1995-10-11 |
フアイザー・インコーポレイテツド |
置換ピペリジンの立体選択的製造
|
FR2677361A1
(fr)
|
1991-06-04 |
1992-12-11 |
Adir |
Nouveaux peptides et pseudopeptides, derives de tachykinines, leur procede de preparation et les compositions pharmaceutiques qui les contiennent.
|
FR2676055B1
(fr)
|
1991-05-03 |
1993-09-03 |
Sanofi Elf |
Composes polycycliques amines et leurs enantiomeres, procede pour leur preparation et compositions pharmaceutiques les contenant.
|
FR2676053B1
(fr)
|
1991-05-03 |
1993-08-27 |
Sanofi Elf |
Nouveaux composes dialkylenepiperidino et leurs enantiomeres, procede pour leur preparation et compositions pharmaceutiques les contenant.
|
FR2676443B1
(fr)
|
1991-05-17 |
1993-08-06 |
Rhone Poulenc Rorer Sa |
Nouveaux derives de perhydroisoindole et leur preparation.
|
FR2676447B1
(fr)
|
1991-05-17 |
1993-08-06 |
Rhone Poulenc Rorer Sa |
Nouveaux derives du thiopyranopyrrole et leur preparation.
|
FR2676442B1
(fr)
|
1991-05-17 |
1993-08-06 |
Rhone Poulenc Rorer Sa |
Nouveau derives de perhydroisoindole, leur preparation et les compositions pharmaceutiques qui les contiennent.
|
FR2676446B1
(fr)
|
1991-05-17 |
1993-08-06 |
Rhone Poulenc Rorer Sa |
Nouveaux derives du thiopyranopyrrole, leur preparation et les compositions pharmaceutiques qui les contiennent.
|
PL170525B1
(en)
|
1991-05-22 |
1996-12-31 |
Pfizer |
Method of obtaining novel derivatives of 3-amino quinuclidine
|
WO1992020661A1
(en)
|
1991-05-22 |
1992-11-26 |
Merck & Co., Inc. |
N, n-diacylpiperazines
|
HU217548B
(hu)
|
1991-05-31 |
2000-02-28 |
Pfizer Inc. |
Kinuklidinszármazékok és ilyen származékokat tartalmazó gyógyászati készítmények
|
GB9113219D0
(en)
|
1991-06-19 |
1991-08-07 |
Fujisawa Pharmaceutical Co |
Peptide compound,processes for preparation thereof and pharmaceutical composition comprising the same
|
DE9290083U1
(de)
|
1991-06-20 |
1994-02-17 |
Pfizer Inc., New York, N.Y. |
Fluoralkoxybenzylamino-Derivate von stickstoffhaltigen Heterocyclen
|
TW202432B
(US06815460-20041109-C00097.png)
|
1991-06-21 |
1993-03-21 |
Pfizer |
|
US5288730A
(en)
|
1991-06-24 |
1994-02-22 |
Merck Sharp & Dohme Limited |
Azabicyclic compounds, pharmaceutical compositions containing them and their use in therapy
|
EP0593557B1
(en)
|
1991-07-05 |
1996-01-31 |
MERCK SHARP & DOHME LTD. |
Aromatic compounds, pharmaceutical compositions containing them and their use in therapy
|
CA2110514A1
(en)
|
1991-07-05 |
1993-01-21 |
Raymond Baker |
Aromatic compounds, pharmaceutical compositions containing them and their use in therapy
|
EP0536817A1
(en)
|
1991-07-05 |
1993-04-14 |
MERCK SHARP & DOHME LTD. |
Azabicyclic compounds as tachykinin antagonists
|
US5495047A
(en)
|
1991-07-10 |
1996-02-27 |
Merck, Sharp & Dohme (Ltd.) |
Fused tricyclic compounds, pharmaceutical compositions containing them and their use in therapy
|
JPH06509090A
(ja)
|
1991-07-10 |
1994-10-13 |
メルク シヤープ エンド ドーム リミテツド |
芳香族化合物、それらを含む組成物、及び治療におけるそれらの使用
|
MY110227A
(en)
|
1991-08-12 |
1998-03-31 |
Ciba Geigy Ag |
1-acylpiperindine compounds.
|
CA2112397A1
(en)
|
1991-08-20 |
1993-03-04 |
Raymond Baker |
Azacyclic compounds, processes for their preparation and pharmaceutical compositions containing them
|
PT533280E
(pt)
|
1991-09-20 |
2001-01-31 |
Glaxo Group Ltd |
Novas utilizacoes medicas para antagonistas de taquiquinina
|
EP0607164B1
(en)
|
1991-09-26 |
2002-05-02 |
Pfizer Inc. |
Fused tricyclic nitrogen containing heterocycles as substance p receptor antagonists
|
WO1993009116A1
(en)
|
1991-11-07 |
1993-05-13 |
Yoshitomi Pharmaceutical Industries, Ltd. |
Quinuclidine compound and medicinal use thereof
|
WO1993010073A1
(en)
|
1991-11-12 |
1993-05-27 |
Pfizer Inc. |
Acyclic ethylenediamine derivatives as substance p receptor antagonists
|
EP0545478A1
(en)
|
1991-12-03 |
1993-06-09 |
MERCK SHARP & DOHME LTD. |
Heterocyclic compounds as tachykinin antagonists
|
HU217629B
(hu)
|
1991-12-12 |
2000-03-28 |
Novartis Ag. |
Eljárás fluvasztatint tartalmazó stabilizált gyógyszerkészítmények előállítására
|
GB9200535D0
(en)
|
1992-01-10 |
1992-02-26 |
Fujisawa Pharmaceutical Co |
New compound
|
GB9201179D0
(en)
|
1992-01-21 |
1992-03-11 |
Glaxo Group Ltd |
Chemical compounds
|
US5328927A
(en)
|
1992-03-03 |
1994-07-12 |
Merck Sharpe & Dohme, Ltd. |
Hetercyclic compounds, processes for their preparation and pharmaceutical compositions containing them
|
JP2656702B2
(ja)
|
1992-03-23 |
1997-09-24 |
ファイザー製薬株式会社 |
ペプチド性キヌクリジン
|
FR2689888B1
(fr)
|
1992-04-10 |
1994-06-10 |
Rhone Poulenc Rorer Sa |
Nouveaux derives de perhydroisoindole, leur preparation et les compositions pharmaceutiques qui les contiennent.
|
AU675786B2
(en)
|
1992-04-15 |
1997-02-20 |
Merck Sharp & Dohme Limited |
Azacyclic compounds
|
GB2266529A
(en)
|
1992-05-01 |
1993-11-03 |
Merck Sharp & Dohme |
Tetrahydroisoquinoline derivatives
|
ES2164657T3
(es)
|
1992-05-18 |
2002-03-01 |
Pfizer |
Derivados aza-biciclicos puenteados como antagonistas de la sustancia p.
|
GB9211193D0
(en)
|
1992-05-27 |
1992-07-08 |
Merck Sharp & Dohme |
Therapeutic agents
|
US5637699A
(en)
|
1992-06-29 |
1997-06-10 |
Merck & Co., Inc. |
Process for preparing morpholine tachykinin receptor antagonists
|
IL106142A
(en)
|
1992-06-29 |
1997-03-18 |
Merck & Co Inc |
Morpholine and thiomorpholine tachykinin receptor antagonists, their preparation and pharmaceutical compositions containing them
|
US5719147A
(en)
|
1992-06-29 |
1998-02-17 |
Merck & Co., Inc. |
Morpholine and thiomorpholine tachykinin receptor antagonists
|
WO1994001402A1
(en)
|
1992-07-13 |
1994-01-20 |
Merck Sharp & Dohme Limited |
Heterocyclic amide derivatives as tachykinin derivatives
|
JPH07509133A
(ja)
|
1992-07-17 |
1995-10-12 |
リボザイム・ファーマシューティカルズ・インコーポレイテッド |
動物疾患の処置のための方法および剤
|
GB2268931A
(en)
|
1992-07-22 |
1994-01-26 |
Merck Sharp & Dohme |
Azabicyclic tachykinin-receptor antagonists
|
US5561130A
(en)
|
1992-07-28 |
1996-10-01 |
Merck Sharp & Dohme Limited |
Azacyclic compounds
|
GB2269170A
(en)
|
1992-07-29 |
1994-02-02 |
Merck Sharp & Dohme |
Azatricyclic tachykinin antagonists
|
WO1994003429A1
(en)
|
1992-07-31 |
1994-02-17 |
Merck Sharp & Dohme Limited |
Substituted amines as tachykinin receptor antagonists
|
US5688804A
(en)
|
1992-08-04 |
1997-11-18 |
Pfizer Inc. |
3-Benzylamino-2-phenyl-piperidine derivatives as substance P receptor antagonists
|
GB9216911D0
(en)
|
1992-08-10 |
1992-09-23 |
Merck Sharp & Dohme |
Therapeutic agents
|
ES2153841T3
(es)
|
1992-08-13 |
2001-03-16 |
Warner Lambert Co |
Antagonistas de la taciquinina.
|
DE69331103T2
(de)
|
1992-08-19 |
2002-03-14 |
Pfizer Inc., New York |
Substituierte benzylamin-stickstoff enthaltende nichtaromatische heterocyclen
|
US5387595A
(en)
|
1992-08-26 |
1995-02-07 |
Merck & Co., Inc. |
Alicyclic compounds as tachykinin receptor antagonists
|
NO179904C
(no)
|
1992-09-04 |
1997-01-08 |
Takeda Chemical Industries Ltd |
Kondenserte heterocykliske forbindelser og deres anvendelse
|
AU4973693A
(en)
|
1992-09-10 |
1994-03-29 |
Merck Sharp & Dohme Limited |
Alcohols and ethers with aromatic substituents as tachykinin-antagonists
|
GB9220286D0
(en)
|
1992-09-25 |
1992-11-11 |
Merck Sharp & Dohme |
Therapeutic agents
|
JP2656699B2
(ja)
|
1992-10-21 |
1997-09-24 |
ファイザー製薬株式会社 |
置換ベンジルアミノキヌクリジン
|
GB9222262D0
(en)
|
1992-10-23 |
1992-12-09 |
Merck Sharp & Dohme |
Therapeutic agents
|
GB9222486D0
(en)
|
1992-10-26 |
1992-12-09 |
Merck Sharp & Dohme |
Therapeutic agents
|
ATE188472T1
(de)
|
1992-10-28 |
2000-01-15 |
Merck Sharp & Dohme |
4-arylmethyloxymethyl piperidine als tachykinin antagonisten
|
JP2656700B2
(ja)
|
1992-10-28 |
1997-09-24 |
ファイザー製薬株式会社 |
置換キヌクリジン誘導体
|
US5554627A
(en)
|
1992-10-30 |
1996-09-10 |
Merck, Sharp & Dohme Ltd. |
Tachykinin antagonists
|
AU676489B2
(en)
|
1992-11-12 |
1997-03-13 |
Pfizer Inc. |
Quinuclidine derivative as substance P antagonist
|
US5261188A
(en)
|
1992-11-23 |
1993-11-16 |
The Standard Products Company |
Belt weatherstrip with bulb
|
ES2147759T3
(es)
|
1992-12-10 |
2000-10-01 |
Pfizer |
Heterociclos no aromaticos sustituidos con aminometileno y uso como antagonistas de la sustancia p.
|
US5604260A
(en)
|
1992-12-11 |
1997-02-18 |
Merck Frosst Canada Inc. |
5-methanesulfonamido-1-indanones as an inhibitor of cyclooxygenase-2
|
JPH08504435A
(ja)
|
1992-12-14 |
1996-05-14 |
メルク シヤープ エンド ドーム リミテツド |
タキキニン受容体拮抗剤としての4−アミノメチル/チオメチル/スルホニルメチル−4−フェニルピペリジン
|
GB9226581D0
(en)
|
1992-12-21 |
1993-02-17 |
Merck Sharp & Dohme |
Therapeutic agents
|
CA2111902A1
(en)
|
1992-12-21 |
1994-06-22 |
Jack Beuford Campbell |
Antitumor compositions and methods of treatment
|
GB9300051D0
(en)
|
1993-01-04 |
1993-03-03 |
Merck Sharp & Dohme |
Therapeutic agents
|
WO1994015932A1
(en)
|
1993-01-15 |
1994-07-21 |
G.D. Searle & Co. |
Novel 3,4-diaryl thiophenes and analogs thereof having use as antiinflammatory agents
|
US5466689A
(en)
|
1993-02-08 |
1995-11-14 |
Takeda Chemical Industries, Ltd. |
Morpholine derivatives and their use
|
DE69410784T2
(de)
|
1993-02-18 |
1999-01-14 |
Merck Sharp & Dohme Ltd., Hoddesdon, Hertfordshire |
Azacyclische verbindungen, sie enthaltende zusammensetzungen und ihre verwendung als tachykinin antagoniste
|
WO1994019320A1
(en)
|
1993-02-22 |
1994-09-01 |
Merck Sharp & Dohme Limited |
Aromatic compounds, compositions containing them and their use in therapy
|
WO1994019357A1
(en)
|
1993-02-23 |
1994-09-01 |
Merrell Dow Pharmaceuticals Inc. |
Farnesyl:protein transferase inhibitors as anticancer agents
|
US5298627A
(en)
|
1993-03-03 |
1994-03-29 |
Warner-Lambert Company |
Process for trans-6-[2-(substituted-pyrrol-1-yl)alkyl]pyran-2-one inhibitors of cholesterol synthesis
|
ATE166650T1
(de)
|
1993-03-04 |
1998-06-15 |
Pfizer |
Spiroazacyclischderivate als substanz p antagonisten
|
US5409944A
(en)
|
1993-03-12 |
1995-04-25 |
Merck Frosst Canada, Inc. |
Alkanesulfonamido-1-indanone derivatives as inhibitors of cyclooxygenase
|
CA2118985A1
(en)
|
1993-04-02 |
1994-10-03 |
Dinesh V. Patel |
Heterocyclic inhibitors of farnesyl protein transferase
|
US5496833A
(en)
|
1993-04-13 |
1996-03-05 |
Merck Sharp & Dohme Limited |
Piperidine tachykinin receptor antagonists
|
ATE158580T1
(de)
|
1993-05-06 |
1997-10-15 |
Merrell Pharma Inc |
Substituierte pyrrolidin-3-alkyl-piperidine verwendbar als tachykinin-antagonisten
|
JPH09500615A
(ja)
|
1993-05-14 |
1997-01-21 |
ジェネンテク,インコーポレイテッド |
Ras−ファルネシル転移酵素阻害剤
|
US5602098A
(en)
|
1993-05-18 |
1997-02-11 |
University Of Pittsburgh |
Inhibition of farnesyltransferase
|
IL109646A0
(en)
|
1993-05-19 |
1994-08-26 |
Pfizer |
Heteroatom substituted alkyl benzylamino-quinuclidines
|
US5380738A
(en)
|
1993-05-21 |
1995-01-10 |
Monsanto Company |
2-substituted oxazoles further substituted by 4-fluorophenyl and 4-methylsulfonylphenyl as antiinflammatory agents
|
CA2163995A1
(en)
|
1993-06-07 |
1994-12-22 |
Malcolm Maccoss |
Spiro-substituted azacycles as neurokinin antagonists
|
US5474995A
(en)
|
1993-06-24 |
1995-12-12 |
Merck Frosst Canada, Inc. |
Phenyl heterocycles as cox-2 inhibitors
|
US5436265A
(en)
|
1993-11-12 |
1995-07-25 |
Merck Frosst Canada, Inc. |
1-aroyl-3-indolyl alkanoic acids and derivatives thereof useful as anti-inflammatory agents
|
GB9602877D0
(en)
|
1996-02-13 |
1996-04-10 |
Merck Frosst Canada Inc |
3,4-Diaryl-2-hydroxy-2,5- dihydrofurans as prodrugs to cox-2 inhibitors
|
EP0634402A1
(en)
|
1993-07-14 |
1995-01-18 |
Takeda Chemical Industries, Ltd. |
Isochinolinone derivatives, their production and use
|
CA2167198C
(en)
|
1993-07-15 |
1999-03-16 |
Kunio Satake |
Benzylaminoquinuclidines
|
TW365603B
(en)
|
1993-07-30 |
1999-08-01 |
Rhone Poulenc Rorer Sa |
Novel perhydroisoindole derivatives, their preparation and pharmaceutical compositions which contain them
|
GB9315808D0
(en)
|
1993-07-30 |
1993-09-15 |
Merck Sharp & Dohme |
Therapeutic agents
|
GB9317987D0
(en)
|
1993-08-26 |
1993-10-13 |
Glaxo Group Ltd |
Chemical compounds
|
ES2217269T3
(es)
|
1993-09-17 |
2004-11-01 |
Pfizer Inc. |
Piperidinas 3-amino-5-carboxi sustituidas y pirrolidinas 3-amino-4-carboxi sustituidas como antagonistas de taquininas.
|
WO1995007908A1
(en)
|
1993-09-17 |
1995-03-23 |
Pfizer Inc. |
Heteroarylamino and heteroarylsulfonamido substituted 3-benzylaminomethyl piperidines and related compounds
|
IS4208A
(is)
|
1993-09-22 |
1995-03-23 |
Glaxo Group Limited |
3-(tetrazólýl-benzyl)amínó-piperadidín afleiður
|
US5728830A
(en)
|
1993-09-22 |
1998-03-17 |
Kyowa Hakko Kogyo Co., Ltd. |
Farnesyltransferase inhibitor
|
US5719148A
(en)
|
1993-10-15 |
1998-02-17 |
Schering Corporation |
Tricyclic amide and urea compounds useful for inhibition of g-protein function and for treatment of proliferative diseases
|
CA2174105C
(en)
|
1993-10-15 |
2002-02-12 |
W. Robert Bishop |
Tricyclic carbamate compounds useful for inhibition of g-protein function and for treatment of proliferative diseases
|
US5721236A
(en)
|
1993-10-15 |
1998-02-24 |
Schering Corporation |
Tricyclic carbamate compounds useful for inhibition of G-protein function and for treatment of proliferative diseases
|
ES2164717T3
(es)
|
1993-10-15 |
2002-03-01 |
Schering Corp |
Compuestos triciclicos de sulfonamida utiles para inhibir la funcion de la proteina-g y para el tratamiento de enfermedades proliferativas.
|
IL111235A
(en)
|
1993-10-15 |
2001-03-19 |
Schering Plough Corp |
Medicinal preparations for inhibiting protein G activity and for the treatment of malignant diseases, containing tricyclic compounds, some such new compounds and a process for the preparation of some of them
|
US5661152A
(en)
|
1993-10-15 |
1997-08-26 |
Schering Corporation |
Tricyclic sulfonamide compounds useful for inhibition of G-protein function and for treatment of proliferative diseases
|
ATE200677T1
(de)
|
1993-10-25 |
2001-05-15 |
Parke Davis & Co |
Substituierte tetra- und pentapeptid hemmstoffe der farnesyl protein transferase
|
WO1995011880A1
(en)
|
1993-10-27 |
1995-05-04 |
Merck Sharp & Dohme Limited |
Substituted amides as tachykinin antagonists
|
US5344991A
(en)
|
1993-10-29 |
1994-09-06 |
G.D. Searle & Co. |
1,2 diarylcyclopentenyl compounds for the treatment of inflammation
|
JPH08505646A
(ja)
|
1993-11-04 |
1996-06-18 |
アボツト・ラボラトリーズ |
スクアレンシンテターゼ及びプロテインファルネシルトランスフェラーゼのインヒビターとしてのシクロブタン誘導体
|
US5783593A
(en)
|
1993-11-04 |
1998-07-21 |
Abbott Laboratories |
Inhibitors of squalene synthetase and protein farnesyltransferase
|
HUT75308A
(en)
|
1993-11-05 |
1997-05-28 |
Warner Lambert Co |
Substituted di- and tripeptide inhibitors of protein:farnesyl transferase
|
US6403577B1
(en)
|
1993-11-17 |
2002-06-11 |
Eli Lilly And Company |
Hexamethyleneiminyl tachykinin receptor antagonists
|
US5466823A
(en)
|
1993-11-30 |
1995-11-14 |
G.D. Searle & Co. |
Substituted pyrazolyl benzenesulfonamides
|
IT1271462B
(it)
|
1993-12-03 |
1997-05-28 |
Menarini Farma Ind |
Antagonisti delle tachichinine,procedimento per la loro preparazione e loro impiego in formulazioni farmaceutiche.
|
US5484799A
(en)
|
1993-12-09 |
1996-01-16 |
Abbott Laboratories |
Antifungal dorrigocin derivatives
|
IL111960A
(en)
|
1993-12-17 |
1999-12-22 |
Merck & Co Inc |
Morpholines and thiomorpholines their preparation and pharmaceutical compositions containing them
|
WO1995017382A1
(en)
|
1993-12-21 |
1995-06-29 |
Eli Lilly And Company |
Non-peptide tachykinin receptor antagonists
|
SK283070B6
(sk)
|
1993-12-29 |
2003-02-04 |
Merck Sharp & Dohme Limited |
Substituované morfolínové deriváty, spôsob ich výroby, farmaceutický prostriedok s ich obsahom a ich použitie
|
US5854239A
(en)
|
1993-12-29 |
1998-12-29 |
Pfizer Inc. |
Diazabicyclic neuokinin antagonists
|
WO1995019344A1
(en)
|
1994-01-13 |
1995-07-20 |
Merck Sharp & Dohme Limited |
Gem-disubstituted azacyclic tachykinin antagonists
|
CA2181376A1
(en)
|
1994-01-28 |
1995-08-03 |
Malcolm Maccoss |
Aralkylamino substituted azacyclic therapeutic agents
|
US5393790A
(en)
|
1994-02-10 |
1995-02-28 |
G.D. Searle & Co. |
Substituted spiro compounds for the treatment of inflammation
|
GB9402688D0
(en)
|
1994-02-11 |
1994-04-06 |
Merck Sharp & Dohme |
Therapeutic agents
|
US5610165A
(en)
|
1994-02-17 |
1997-03-11 |
Merck & Co., Inc. |
N-acylpiperidine tachykinin antagonists
|
TW385308B
(en)
|
1994-03-04 |
2000-03-21 |
Merck & Co Inc |
Prodrugs of morpholine tachykinin receptor antagonists
|
WO1995024612A1
(de)
|
1994-03-07 |
1995-09-14 |
International Business Machines Corporation |
Verfahren und vorrichtung zur schnellen interpolation von zwischenwerten aus periodischen phasenverschobenen signalen und zur erkennung von defekten in einem drehkörper
|
JP3969737B2
(ja)
|
1994-03-15 |
2007-09-05 |
エーザイ株式会社 |
イソプレニルトランスフェラーゼ阻害剤
|
FR2718136B1
(fr)
|
1994-03-29 |
1996-06-21 |
Sanofi Sa |
Composés aromatiques aminés, procédé pour leur obtention et compositions pharmaceutiques les contenant.
|
HUT72440A
(en)
|
1994-03-31 |
1996-04-29 |
Bristol Myers Squibb Co |
Imidazole-containing inhibitors of farnesyl protein transferase and pharmaceutical compositions containing them
|
US5523430A
(en)
|
1994-04-14 |
1996-06-04 |
Bristol-Myers Squibb Company |
Protein farnesyl transferase inhibitors
|
US5610145A
(en)
|
1994-04-15 |
1997-03-11 |
Warner-Lambert Company |
Tachykinin antagonists
|
US5362718A
(en)
|
1994-04-18 |
1994-11-08 |
American Home Products Corporation |
Rapamycin hydroxyesters
|
CZ104795A3
(en)
|
1994-04-29 |
1996-02-14 |
Lilly Co Eli |
Benzimidazole derivative, process of its preparation, its use for preparing a pharmaceutical preparation and the pharmaceutical composition containing thereof
|
EP0758329A1
(en)
|
1994-05-05 |
1997-02-19 |
MERCK SHARP & DOHME LTD. |
Morpholine derivatives and their use as antagonists of tachikinins
|
CA2189764A1
(en)
|
1994-05-07 |
1995-11-16 |
Gerd Schnorrenberg |
Neurokinine (tachykinine) antagonists
|
US5510510A
(en)
|
1994-05-10 |
1996-04-23 |
Bristol-Meyers Squibb Company |
Inhibitors of farnesyl protein transferase
|
US5563255A
(en)
|
1994-05-31 |
1996-10-08 |
Isis Pharmaceuticals, Inc. |
Antisense oligonucleotide modulation of raf gene expression
|
DE69523154T2
(de)
|
1994-06-06 |
2002-06-06 |
Warner-Lambert Co., Morris Plains |
Tachykinin (nk1) rezeptor antagonisten
|
EP0764149B1
(fr)
|
1994-06-10 |
1999-01-20 |
Aventis Pharma S.A. |
Nouveaux inhibiteurs de farnesyl transferase, leur preparation et les compositions pharmaceutiques qui les contiennent
|
CA2150992A1
(en)
|
1994-06-10 |
1995-12-11 |
Philip Arthur Hipskind |
Cyclohexyl tachykinin receptor antagonists
|
US5571792A
(en)
|
1994-06-30 |
1996-11-05 |
Warner-Lambert Company |
Histidine and homohistidine derivatives as inhibitors of protein farnesyltransferase
|
BR9508375A
(pt)
|
1994-07-12 |
1997-10-28 |
Lilly Co Eli |
Antagonista de receptor de taquicinina heterociclica
|
CA2154116A1
(en)
|
1994-07-22 |
1996-01-23 |
Philip Arthur Hipskind |
1-aryl-2-acetamidopentanone derivatives for use as tachykinin receptor antagonists
|
GB9415996D0
(en)
|
1994-08-08 |
1994-09-28 |
Merck Sharp & Dohme |
Therapeutic agents
|
GB9415997D0
(en)
|
1994-08-08 |
1994-09-28 |
Merck Sharp & Dohme |
Therapeutic agents
|
WO1996005529A1
(en)
|
1994-08-09 |
1996-02-22 |
Micron Optics, Inc. |
Temperature compensated fiber fabry-perot filters
|
TW432061B
(en)
|
1994-08-09 |
2001-05-01 |
Pfizer Res & Dev |
Lactams
|
CA2155448A1
(en)
|
1994-08-11 |
1996-02-12 |
Katerina Leftheris |
Inhibitors of farnesyl protein transferase
|
DE69514367T2
(de)
|
1994-08-11 |
2000-07-27 |
Banyu Pharmaceutical Co., Ltd. |
Substituierte amidderivate
|
EP0805154A1
(en)
|
1994-08-12 |
1997-11-05 |
Banyu Pharmaceutical Co., Ltd. |
N,n-disubstituted amic acid derivative
|
PT777659E
(pt)
|
1994-08-15 |
2001-09-28 |
Merck Sharp & Dohme |
Derivados de morfolina e sua utilizacao como agentes terapeuticos
|
DE4429506B4
(de)
|
1994-08-19 |
2007-09-13 |
Degussa Gmbh |
Verfahren zur Extraktion natürlicher Carotinoid-Farbstoffe
|
DE4429653C2
(de)
|
1994-08-20 |
1997-04-03 |
Anton Dr More |
Konverter und Verfahren zum Frischen von Metallschmelzen insbesondere von Roheisen zu Stahl
|
WO1996006094A1
(en)
|
1994-08-25 |
1996-02-29 |
Merrell Pharmaceuticals Inc. |
Novel substituted piperidines useful for the treatment of allergic diseases
|
DE69405864T2
(de)
|
1994-08-29 |
1998-03-26 |
Akzo Nobel Nv |
Verfahren zur Herstellung von quaternären Diestern
|
GB9417956D0
(en)
|
1994-09-02 |
1994-10-26 |
Merck Sharp & Dohme |
Therapeutic agents
|
GB9418545D0
(en)
|
1994-09-15 |
1994-11-02 |
Merck Sharp & Dohme |
Therapeutic agents
|
US5457107A
(en)
|
1994-09-16 |
1995-10-10 |
Merck & Co., Inc. |
Polymorphic form of a tachykinin receptor antagonist
|
ATE212981T1
(de)
|
1994-09-30 |
2002-02-15 |
Novartis Erfind Verwalt Gmbh |
1-acyl-4-aliphatische aminopiperidin verbindungen
|
TW397825B
(en)
|
1994-10-14 |
2000-07-11 |
Novartis Ag |
Aroyl-piperidine derivatives
|
FR2725986B1
(fr)
|
1994-10-21 |
1996-11-29 |
Adir |
Nouveaux derives de piperidine, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
|
EP0709375B1
(en)
|
1994-10-25 |
2005-05-18 |
AstraZeneca AB |
Therapeutic heterocycles
|
GB9421709D0
(en)
|
1994-10-27 |
1994-12-14 |
Zeneca Ltd |
Therapeutic compounds
|
KR100389754B1
(ko)
|
1994-11-22 |
2003-10-17 |
코닌클리즈케 필립스 일렉트로닉스 엔.브이. |
반도체장치
|
EP0714891A1
(en)
|
1994-11-22 |
1996-06-05 |
Eli Lilly And Company |
Heterocyclic tachykinin receptor antagonists
|
FR2727411B1
(fr)
|
1994-11-30 |
1997-01-03 |
Rhone Poulenc Rorer Sa |
Nouveaux derives de perhydroisoindole, leur preparation et les compositions pharmaceutiques qui les contiennent
|
AU3971295A
(en)
|
1994-12-09 |
1996-06-26 |
Warner-Lambert Company |
Substituted tetra- and pentapeptide inhibitors of protein:farnesyl transferase
|
IL116323A0
(en)
|
1994-12-13 |
1996-03-31 |
Sandoz Ag |
Tachykinin antagonists their preparation and pharmaceutical compositions containing them
|
GB9426103D0
(en)
|
1994-12-23 |
1995-02-22 |
Merck Sharp & Dohme |
Therapeutic agents
|
EA000164B1
(ru)
|
1995-01-09 |
1998-10-29 |
Магла Интернэшнл Лтд. |
Состав для печати изображения на поверхности изделия из каучукового латекса, способ печати изображения и изделия из каучукового латекса
|
AU4915796A
(en)
|
1995-01-12 |
1996-07-31 |
University Of Pittsburgh |
Inhibitors of prenyl transferases
|
ES2229259T3
(es)
|
1995-01-12 |
2005-04-16 |
Glaxo Group Limited |
Derivados de piperidina con actividad antagonista de taquiquinina.
|
FR2729390A1
(fr)
|
1995-01-18 |
1996-07-19 |
Rhone Poulenc Rorer Sa |
Nouveaux inhibiteurs de farnesyl transferase, leur preparation et les compositions pharmaceutiques qui les contiennent
|
FR2729951B1
(fr)
|
1995-01-30 |
1997-04-18 |
Sanofi Sa |
Nouveaux composes heterocycliques, procede pour leur preparation et compositions pharmaceutiques en contenant
|
FR2730492B1
(fr)
|
1995-02-09 |
1997-03-14 |
Rhone Poulenc Rorer Sa |
Nouveaux inhibiteurs de farnesyl transferase, leur preparation et les compositions pharmaceutiques qui les contiennent
|
FR2730491B1
(fr)
|
1995-02-09 |
1997-03-14 |
Rhone Poulenc Rorer Sa |
Nouveaux inhibiteurs de farnesyl transferase, leur preparation et les compositions pharmaceutiques qui les contiennent
|
US5633272A
(en)
|
1995-02-13 |
1997-05-27 |
Talley; John J. |
Substituted isoxazoles for the treatment of inflammation
|
GB9505492D0
(en)
|
1995-03-18 |
1995-05-03 |
Merck Sharp & Dohme |
Therapeutic agents
|
GB9505491D0
(en)
|
1995-03-18 |
1995-05-03 |
Merck Sharp & Dohme |
Therapeutic agents
|
US5554641A
(en)
|
1995-03-20 |
1996-09-10 |
Horwell; David C. |
Nonpeptides as tachykinin antagonists
|
GB9505692D0
(en)
|
1995-03-21 |
1995-05-10 |
Glaxo Group Ltd |
Chemical compounds
|
US5700806A
(en)
|
1995-03-24 |
1997-12-23 |
Schering Corporation |
Tricyclic amide and urea compounds useful for inhibition of G-protein function and for treatment of proliferative diseases
|
US5684013A
(en)
|
1995-03-24 |
1997-11-04 |
Schering Corporation |
Tricyclic compounds useful for inhibition of g-protein function and for treatment of proliferative diseases
|
DE69628484T2
(de)
|
1995-03-24 |
2004-05-19 |
Takeda Chemical Industries, Ltd. |
Zyklische Verbindungen, ihre Herstellung und ihre Verwendung als Tachykininrezeptorantagonisten
|
IL117580A0
(en)
|
1995-03-29 |
1996-07-23 |
Merck & Co Inc |
Inhibitors of farnesyl-protein transferase and pharmaceutical compositions containing them
|
US5565568A
(en)
|
1995-04-06 |
1996-10-15 |
Eli Lilly And Company |
2-acylaminopropanamides as tachykinin receptor antagonists
|
IL117798A
(en)
|
1995-04-07 |
2001-11-25 |
Schering Plough Corp |
Tricyclic compounds useful for inhibiting the function of protein - G and for the treatment of malignant diseases, and pharmaceutical preparations containing them
|
WO1996031501A1
(en)
|
1995-04-07 |
1996-10-10 |
Schering Corporation |
Carbonyl-piperazinyl and piperidinil compounds which inhibit farnesyl protein transferase
|
US5891872A
(en)
|
1995-04-07 |
1999-04-06 |
Schering Corporation |
Tricyclic compounds
|
US5712280A
(en)
|
1995-04-07 |
1998-01-27 |
Schering Corporation |
Tricyclic compounds useful for inhibition of G-protein function and for treatment of proliferative diseases
|
ATE277021T1
(de)
|
1995-04-13 |
2004-10-15 |
Aventis Pharma Inc |
Neue substituierte piperazinderivate mit tachykininrezeptor-antagonistischer wirkung
|
US5831115A
(en)
|
1995-04-21 |
1998-11-03 |
Abbott Laboratories |
Inhibitors of squalene synthase and protein farnesyltransferase
|
IL118101A0
(en)
|
1995-05-03 |
1996-09-12 |
Abbott Lab |
Inhibitors of farnesyltransferase
|
JP3071829B2
(ja)
|
1995-05-25 |
2000-07-31 |
藤沢薬品工業株式会社 |
ニューロキニン受容体拮抗剤としての1−ベンゾイル−2−(インドリル−3−アルキル)−ピペラジン誘導体
|
AU6034296A
(en)
|
1995-06-16 |
1997-01-15 |
Warner-Lambert Company |
Tricyclic inhibitors of protein farnesyltransferase
|
GB9513117D0
(en)
|
1995-06-28 |
1995-08-30 |
Merck Sharp & Dohme |
Therapeutic agents
|
GB9513121D0
(en)
|
1995-06-28 |
1995-08-30 |
Merck Sharp & Dohme |
Therapeutic agents
|
GB9513118D0
(en)
|
1995-06-28 |
1995-08-30 |
Merck Sharp & Dohme |
Therapeutic agents
|
ES2155601T3
(es)
|
1995-07-07 |
2001-05-16 |
Pfizer |
Compuestos de benzolactama sustituidos como antagonistas de la sustancia p.
|
FR2736641B1
(fr)
|
1995-07-10 |
1997-08-22 |
Rhone Poulenc Rorer Sa |
Nouveaux inhibiteurs de farnesyl transferase, leur preparation et les compositions pharmaceutiques qui les contiennent
|
AT402617B
(de)
|
1995-07-11 |
1997-07-25 |
Datacon Schweitzer & Zeindl Gm |
Anlage zum automatisierten, hermetischen anlage zum automatisierten, hermetischen verschliessen von gehäusen verschliessen von gehäusen
|
FR2736638B1
(fr)
|
1995-07-12 |
1997-08-22 |
Rhone Poulenc Rorer Sa |
Nouveaux inhibiteurs de farnesyl transferase, leur preparation et les compositions pharmaceutiques qui les contiennent
|
CH690163A5
(fr)
|
1995-07-28 |
2000-05-31 |
Symphar Sa |
Dérivés gem-diphosphonates substitués utiles en tant qu'agents anti-cancers.
|
TW340842B
(en)
|
1995-08-24 |
1998-09-21 |
Pfizer |
Substituted benzylaminopiperidine compounds
|
US6020343A
(en)
|
1995-10-13 |
2000-02-01 |
Merck Frosst Canada, Inc. |
(Methylsulfonyl)phenyl-2-(5H)-furanones as COX-2 inhibitors
|
JP2002534955A
(ja)
|
1995-10-18 |
2002-10-15 |
メルク エンド カンパニー インコーポレーテッド |
シクロペンチルタキキニン受容体アンタゴニスト
|
WO1997017070A1
(en)
|
1995-11-06 |
1997-05-15 |
University Of Pittsburgh |
Inhibitors of protein isoprenyl transferases
|
DE19541283A1
(de)
|
1995-11-06 |
1997-05-07 |
Boehringer Ingelheim Kg |
Neue Aminosäurederivate, Verfahren zu ihrer Herstellung und diese Verbindungen enthaltende pharmazeutische Zusammensetzungen
|
GB9523244D0
(en)
|
1995-11-14 |
1996-01-17 |
Merck Sharp & Dohme |
Therapeutic agents
|
DE59610712D1
(de)
|
1995-11-17 |
2003-10-16 |
Biotechnolog Forschung Gmbh |
Epothilonderivate, herstellung und verwendung
|
EP0862435A4
(en)
|
1995-11-22 |
1999-02-03 |
Merck & Co Inc |
INHIBITORS OF FARNESYL PROTEIN TRANSFERASE
|
US6060469A
(en)
|
1995-11-23 |
2000-05-09 |
Merck Sharp & Dohme Ltd. |
Spiro-piperidine derivatives and their use as tachykinin antagonists
|
GB9524157D0
(en)
|
1995-11-25 |
1996-01-24 |
Pfizer Ltd |
Therapeutic agents
|
RU2135494C1
(ru)
|
1995-12-01 |
1999-08-27 |
Санкио Компани Лимитед |
Гетероциклические соединения и композиция на их основе, проявляющая антагонистическое действие в отношении рецепторов тахикинина
|
EP1162201B1
(en)
|
1995-12-08 |
2006-03-29 |
Janssen Pharmaceutica N.V. |
Farnesyl protein transferase inhibiting (imidazol-5-yl)methyl-2-quinolinone derivatives
|
GB9525296D0
(en)
|
1995-12-11 |
1996-02-07 |
Merck Sharp & Dohme |
Therapeutic agents
|
NZ326035A
(en)
|
1995-12-22 |
2000-01-28 |
Schering Corp |
Tricyclic amides useful for inhibition of g-protein function and for treatment of proliferative diseases
|
WO1997026246A1
(en)
|
1996-01-16 |
1997-07-24 |
Warner-Lambert Company |
Substituted histidine inhibitors of protein farnesyltransferase
|
US6673927B2
(en)
|
1996-02-16 |
2004-01-06 |
Societe De Conseils De Recherches Et D'applications Scientifiques, S.A.S. |
Farnesyl transferase inhibitors
|
JP2001519766A
(ja)
|
1996-04-03 |
2001-10-23 |
メルク エンド カンパニー インコーポレーテッド |
ファルネシルタンパク質トランスフェラーゼの阻害剤
|
EE03685B1
(et)
|
1996-04-12 |
2002-04-15 |
G.D. Searle & Co. |
Asendatud benseensulfoonamiidi derivaadid kui COX-2 inhibiitorite eelravimid
|
NZ332712A
(en)
|
1996-05-22 |
2000-07-28 |
Warner Lambert Co |
Polypeptide inhibitors of protein farnesyl transferase
|
AU709409B2
(en)
|
1996-07-15 |
1999-08-26 |
Bristol-Myers Squibb Company |
Thiadioxobenzodiazepine inhibitors of farnesyl protein transferase
|
US5861419A
(en)
|
1996-07-18 |
1999-01-19 |
Merck Frosst Canad, Inc. |
Substituted pyridines as selective cyclooxygenase-2 inhibitors
|
EP1386922B1
(en)
|
1996-12-03 |
2012-04-11 |
Sloan-Kettering Institute For Cancer Research |
Synthesis of epothilones, intermediates thereof, analogues and uses thereof
|
EP0951285A1
(en)
|
1996-12-30 |
1999-10-27 |
Merck & Co., Inc. |
Inhibitors of farnesyl-protein transferase
|
JP2002511054A
(ja)
|
1996-12-30 |
2002-04-09 |
メルク エンド カンパニー インコーポレーテッド |
ファルネシル蛋白トランスフェラーゼ阻害薬
|
JP2002536968A
(ja)
|
1999-01-29 |
2002-11-05 |
イムクローン システムズ インコーポレイティド |
Kdrに特異的な抗体およびその使用
|
GB9904387D0
(en)
|
1999-02-25 |
1999-04-21 |
Pharmacia & Upjohn Spa |
Antitumour synergistic composition
|
WO2000061186A1
(en)
|
1999-04-08 |
2000-10-19 |
Arch Development Corporation |
Use of anti-vegf antibody to enhance radiation in cancer therapy
|
US6545004B1
(en)
|
1999-10-27 |
2003-04-08 |
Cytokinetics, Inc. |
Methods and compositions utilizing quinazolinones
|
JP2003512461A
(ja)
|
1999-10-27 |
2003-04-02 |
サイトキネティクス・インコーポレーテッド |
キナゾリノンを用いた方法並びに組成
|
AU2002252614B2
(en)
|
2001-04-10 |
2006-09-14 |
Merck Sharp & Dohme Corp. |
Inhibitors of Akt activity
|
WO2002083140A1
(en)
|
2001-04-10 |
2002-10-24 |
Merck & Co., Inc. |
Inhibitors of akt activity
|
WO2002083675A2
(en)
|
2001-04-10 |
2002-10-24 |
Merck Sharp & Dohme Limited |
Inhibitors of akt activity
|
WO2002083139A1
(en)
|
2001-04-10 |
2002-10-24 |
Merck & Co., Inc. |
Inhibitors of akt activity
|
WO2003013526A1
(en)
|
2001-08-08 |
2003-02-20 |
Merck & Co. Inc. |
Anticoagulant compounds
|
WO2003039460A2
(en)
|
2001-11-07 |
2003-05-15 |
Merck & Co., Inc. |
Mitotic kinesin inhibitors
|
AU2002364128B2
(en)
|
2001-12-06 |
2008-03-06 |
Merck Sharp & Dohme Corp. |
Mitotic kinesin inhibitors
|
US7262186B2
(en)
|
2001-12-06 |
2007-08-28 |
Merck & Co., Inc. |
Substituted pyrazolo[3,4-d] pyrimidinones as a mitotic kinesin inhibitor
|
EP1481077B1
(en)
|
2001-12-06 |
2009-11-04 |
Merck & Co., Inc. |
Mitotic kinesin inhibitors
|
EP1463733B1
(en)
|
2001-12-06 |
2007-09-05 |
Merck & Co., Inc. |
Mitotic kinesin inhibitors
|
WO2003049678A2
(en)
|
2001-12-06 |
2003-06-19 |
Merck & Co., Inc. |
Mitotic kinesin inhibitors
|
MXPA04007402A
(es)
|
2002-02-01 |
2005-06-17 |
Ariad Gene Therapeutics Inc |
Compuestos que contienen fosforo y usos de los mismos.
|
DE60329990D1
(de)
|
2002-03-08 |
2009-12-24 |
Merck & Co Inc |
Mitotische kinesin-hemmer
|
WO2003086403A1
(en)
|
2002-04-08 |
2003-10-23 |
Merck & Co., Inc. |
Inhibitors of akt activity
|
US7273869B2
(en)
|
2002-04-08 |
2007-09-25 |
Merck & Co., Inc. |
Inhibitors of Akt activity
|
WO2003086394A1
(en)
|
2002-04-08 |
2003-10-23 |
Merck & Co., Inc. |
Inhibitors of akt activity
|
AU2003226250B2
(en)
|
2002-04-08 |
2007-08-16 |
Merck Sharp & Dohme Corp. |
Inhibitors of Akt activity
|
AU2003299517A1
(en)
|
2002-05-23 |
2004-05-25 |
Merck & Co., Inc. |
Mitotic kinesin inhibitors
|
AU2003231799A1
(en)
|
2002-05-23 |
2003-12-12 |
Merck & Co., Inc. |
Mitotic kinesin inhibitors
|
CA2486215A1
(en)
|
2002-06-14 |
2003-12-24 |
Merck & Co., Inc. |
Mitotic kinesin inhibitors
|
AU2003245453B2
(en)
|
2002-06-14 |
2008-08-14 |
Merck Sharp & Dohme Corp. |
Mitotic kinesin inhibitors
|
CA2494962C
(en)
*
|
2002-08-09 |
2011-06-14 |
Merck & Co., Inc. |
Tyrosine kinase inhibitors
|
TW200526684A
(en)
|
2003-11-21 |
2005-08-16 |
Schering Corp |
Anti-IGFR1 antibody therapeutic combinations
|
US20060247320A1
(en)
|
2005-03-09 |
2006-11-02 |
Schering Corporation |
Compounds for inhibiting KSP kinesin activity
|
AR053158A1
(es)
|
2005-03-09 |
2007-04-25 |
Schering Corp |
Compuestos para inhibir la actividad de quinesina de ksp
|
KR20080042897A
(ko)
*
|
2005-09-09 |
2008-05-15 |
아날리테콘에스.에이. |
Igf-1r 억제제로서 이소퀴놀린
|
KR20080065591A
(ko)
*
|
2005-09-09 |
2008-07-14 |
아날리테콘에스.에이. |
Igf-1r 억제제로서 이소퀴놀린 유도체
|
MY149430A
(en)
|
2005-12-13 |
2013-08-30 |
Merck Sharp & Dohme |
Polycyclic indazole derivatives that are erk inhibitors
|
JP2009528280A
(ja)
|
2006-02-16 |
2009-08-06 |
シェーリング コーポレイション |
Erkインヒビターとしてのピロリジン誘導体
|
EP2170893A1
(en)
|
2007-06-18 |
2010-04-07 |
Schering Corporation |
Heterocyclic compounds and use thereof as erk inhibitors
|
WO2012145471A1
(en)
*
|
2011-04-21 |
2012-10-26 |
Merck Sharp & Dohme Corp. |
Insulin-like growth factor-1 receptor inhibitors
|