SI2448945T1 - Kristalinične oblike prasugrelovih soli - Google Patents
Kristalinične oblike prasugrelovih soliInfo
- Publication number
- SI2448945T1 SI2448945T1 SI201130445T SI201130445T SI2448945T1 SI 2448945 T1 SI2448945 T1 SI 2448945T1 SI 201130445 T SI201130445 T SI 201130445T SI 201130445 T SI201130445 T SI 201130445T SI 2448945 T1 SI2448945 T1 SI 2448945T1
- Authority
- SI
- Slovenia
- Prior art keywords
- crystalline forms
- prasugrel
- salts
- prasugrel salts
- crystalline
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D495/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
- A61K31/4365—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system having sulfur as a ring hetero atom, e.g. ticlopidine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Applications Claiming Priority (6)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US32216510P | 2010-04-08 | 2010-04-08 | |
US32688210P | 2010-04-22 | 2010-04-22 | |
US34891410P | 2010-05-27 | 2010-05-27 | |
US35530410P | 2010-06-16 | 2010-06-16 | |
PCT/US2011/031602 WO2011127300A1 (en) | 2010-04-08 | 2011-04-07 | Crystalline forms of prasugrel salts |
EP11715144.9A EP2448945B1 (en) | 2010-04-08 | 2011-04-07 | Crystalline forms of prasugrel salts |
Publications (1)
Publication Number | Publication Date |
---|---|
SI2448945T1 true SI2448945T1 (sl) | 2015-05-29 |
Family
ID=44065677
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SI201130445T SI2448945T1 (sl) | 2010-04-08 | 2011-04-07 | Kristalinične oblike prasugrelovih soli |
Country Status (11)
Country | Link |
---|---|
US (2) | US8802854B2 (sl) |
EP (2) | EP2883877A1 (sl) |
JP (2) | JP5730986B2 (sl) |
KR (3) | KR20120052381A (sl) |
CN (1) | CN102656175B (sl) |
ES (1) | ES2533681T3 (sl) |
HR (1) | HRP20150356T1 (sl) |
PL (1) | PL2448945T3 (sl) |
PT (1) | PT2448945E (sl) |
SI (1) | SI2448945T1 (sl) |
WO (1) | WO2011127300A1 (sl) |
Families Citing this family (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
KR20120052381A (ko) | 2010-04-08 | 2012-05-23 | 테바 파마슈티컬 인더스트리즈 리미티드 | 프라수그렐 염의 결정형 |
CZ305314B6 (cs) * | 2010-12-30 | 2015-07-29 | Zentiva, K.S. | Nový hydrobromid formy C 5-[2-cyklopropyl-1-(2-fluorofenyl)-2-oxoethyl]-4,5,6,7-tetrahydrothieno[3,2-c]pyridin-2-yl acetátu známého pod nechráněným názvem prasugrel a způsob jeho výroby |
CN103173432B (zh) | 2011-12-22 | 2020-08-04 | 通用电气公司 | 分离核酸的方法及装置 |
CN103012427B (zh) * | 2012-11-26 | 2015-07-08 | 天津大学 | 一种普拉格雷盐酸盐乙醇溶剂化物及其制备方法 |
WO2016203018A1 (en) | 2015-06-19 | 2016-12-22 | Sanovel Ilac Sanayi Ve Ticaret A.S. | Pharmaceutical compositions of prasugrel hydrobromide |
EP3158993A1 (en) | 2015-10-22 | 2017-04-26 | Zaklady Farmaceutyczne Polpharma SA | Process for preparing a tablet comprising prasugrel or pharmaceutically acceptable salt thereof |
CN107814810A (zh) * | 2016-09-14 | 2018-03-20 | 天津科技大学 | 一种普拉格雷硫酸氢盐新晶型及其制备方法 |
CN107915743A (zh) * | 2016-10-10 | 2018-04-17 | 天津科技大学 | 一种普拉格雷硫酸氢盐晶型iv及其制备方法 |
Family Cites Families (21)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FI101150B (fi) | 1991-09-09 | 1998-04-30 | Sankyo Co | Menetelmä lääkeaineina käyttökelpoisten tetrahydrotienopyridiinin johd annaisten valmistamiseksi |
KR20090033917A (ko) | 2000-07-06 | 2009-04-06 | 다이이찌 산쿄 가부시키가이샤 | 히드로피리딘 유도체 산부가염 |
TWI392681B (zh) | 2006-04-06 | 2013-04-11 | Daiichi Sankyo Co Ltd | 高純度普拉格雷及其酸加成鹽之製法 |
US20100204470A1 (en) | 2006-06-27 | 2010-08-12 | Sandoz Ag | method for salt preparation |
US20100261908A1 (en) | 2007-11-09 | 2010-10-14 | Dr. Reddy's Laboratories Ltd. | Processes for the preparation of prasugrel , and its salts and polymorphs |
WO2009066326A2 (en) | 2007-11-19 | 2009-05-28 | Msn Laboratories Limited | Improved process for the preparation of prasugrel and its pharmaceutically acceptable salts |
WO2009098142A1 (en) | 2008-02-06 | 2009-08-13 | Helm Ag | Prasugrel salts with improved properties |
CN101255169B (zh) | 2008-03-26 | 2010-11-10 | 山东大学 | 普拉格雷盐及其制备方法 |
WO2009129983A1 (en) | 2008-04-21 | 2009-10-29 | Ratiopharm Gmbh | Acid addition salts of prasugrel and pharmaceutical compositions comprising the same |
ES2353853T3 (es) | 2008-04-25 | 2011-03-07 | Sandoz Ag | SAL HIDROGENOSULFATO DE 2-ACETOXI-5-("ALFA"-CICLOPROPILCARBONIL-2-FLUORBENCIL)-4,5,6,7-TETRAHIDROTIENO[3,2-c]PIRIDINA Y SU PREPARACIÓN. |
EP2325187A4 (en) | 2008-08-02 | 2011-09-28 | Lunan Pharm Group Corp | PRASUGREL HYDROGENOSULFATE, ITS MEDICINAL COMPOUND AND USE THEREOF |
WO2010070677A2 (en) | 2008-12-15 | 2010-06-24 | Glenmark Generics Limited | A process for the preparation of prasugrel and its pharmaceutically acceptable salts thereof |
EP2398468B1 (en) | 2009-02-17 | 2016-11-30 | KRKA, D.D., Novo Mesto | Pharmaceutical compositions comprising prasugrel base or its pharmaceutically acceptable acid addition salts and processes for their preparation |
RU2484094C1 (ru) * | 2009-03-31 | 2013-06-10 | Шанхай Инститьют Оф Фармасьютикал Индастри | Кристаллы гидробромата прасугреля |
GB2469883A (en) | 2009-04-30 | 2010-11-03 | Sandoz Ag | Novel crystalline form of Prasugrel hydrogensulphate |
EP2451816A4 (en) | 2009-07-06 | 2013-02-27 | Glenmark Generics Ltd | CRYSTALLINE FORM OF PRASUGREL HYDROBROMIDE AND PROCESS FOR PREPARING THE SAME |
CZ2009762A3 (cs) * | 2009-11-16 | 2011-05-25 | Zentiva, K. S. | Nové soli 5-[2-cyklopropyl-1-(2-fluorfenyl)-2-oxoethyl]-4,5,6,7-tetrahydrothieno[3,2-c]pyridin-2-yl acetátu známého pod nechráneným názvem prasugrel a zpusob jejich výroby |
CZ2009763A3 (cs) * | 2009-11-16 | 2011-05-25 | Zentiva, K. S. | Zpusob výroby vysoce cistého 5-[2-cyklopropyl-1-(2-fluorfenyl)-2-oxoethyl]-4,5,6,7-tetrahydrothieno[3,2-c]pyridin-2-yl acetátu známého pod nechráneným názvem prasugrel a jeho nových farmaceuticky prijatelných solí. |
KR20120052381A (ko) | 2010-04-08 | 2012-05-23 | 테바 파마슈티컬 인더스트리즈 리미티드 | 프라수그렐 염의 결정형 |
CN101899056A (zh) | 2010-08-02 | 2010-12-01 | 江苏万全特创医药生物技术有限公司 | 普拉格雷氢溴酸盐多晶型物及其制备方法 |
CN101919823A (zh) * | 2010-08-02 | 2010-12-22 | 北京德众万全医药科技有限公司 | 一种治疗血栓的药用组合物 |
-
2011
- 2011-04-07 KR KR1020127005672A patent/KR20120052381A/ko active Application Filing
- 2011-04-07 US US13/639,453 patent/US8802854B2/en active Active
- 2011-04-07 SI SI201130445T patent/SI2448945T1/sl unknown
- 2011-04-07 WO PCT/US2011/031602 patent/WO2011127300A1/en active Application Filing
- 2011-04-07 ES ES11715144.9T patent/ES2533681T3/es active Active
- 2011-04-07 JP JP2013503957A patent/JP5730986B2/ja not_active Expired - Fee Related
- 2011-04-07 KR KR1020157034317A patent/KR101785186B1/ko active IP Right Grant
- 2011-04-07 EP EP15150045.1A patent/EP2883877A1/en not_active Withdrawn
- 2011-04-07 PT PT117151449T patent/PT2448945E/pt unknown
- 2011-04-07 CN CN201180004008.XA patent/CN102656175B/zh active Active
- 2011-04-07 PL PL11715144T patent/PL2448945T3/pl unknown
- 2011-04-07 EP EP11715144.9A patent/EP2448945B1/en active Active
- 2011-04-07 KR KR1020147023295A patent/KR20140110096A/ko active Application Filing
-
2014
- 2014-07-22 US US14/337,846 patent/US9012641B2/en active Active
-
2015
- 2015-02-04 JP JP2015020103A patent/JP2015096553A/ja active Pending
- 2015-03-30 HR HRP20150356TT patent/HRP20150356T1/hr unknown
Also Published As
Publication number | Publication date |
---|---|
CN102656175B (zh) | 2015-08-26 |
KR20150140871A (ko) | 2015-12-16 |
ES2533681T3 (es) | 2015-04-14 |
EP2448945B1 (en) | 2015-01-07 |
US9012641B2 (en) | 2015-04-21 |
JP2013523837A (ja) | 2013-06-17 |
PL2448945T3 (pl) | 2015-06-30 |
CN102656175A (zh) | 2012-09-05 |
US20140336217A1 (en) | 2014-11-13 |
EP2448945A1 (en) | 2012-05-09 |
WO2011127300A1 (en) | 2011-10-13 |
KR20120052381A (ko) | 2012-05-23 |
JP5730986B2 (ja) | 2015-06-10 |
US20130085154A1 (en) | 2013-04-04 |
KR20140110096A (ko) | 2014-09-16 |
EP2883877A1 (en) | 2015-06-17 |
KR101785186B1 (ko) | 2017-10-12 |
HRP20150356T1 (hr) | 2015-05-08 |
PT2448945E (pt) | 2015-04-09 |
JP2015096553A (ja) | 2015-05-21 |
US8802854B2 (en) | 2014-08-12 |
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