PT2571355T - Sal de cloridrato cristalino de darunavir - Google Patents
Sal de cloridrato cristalino de darunavirInfo
- Publication number
- PT2571355T PT2571355T PT108516964T PT10851696T PT2571355T PT 2571355 T PT2571355 T PT 2571355T PT 108516964 T PT108516964 T PT 108516964T PT 10851696 T PT10851696 T PT 10851696T PT 2571355 T PT2571355 T PT 2571355T
- Authority
- PT
- Portugal
- Prior art keywords
- darunavir
- hydrochloride salt
- crystalline hydrochloride
- crystalline
- salt
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
- C07D493/02—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
- C07D493/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D307/93—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems condensed with a ring other than six-membered
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Virology (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Oncology (AREA)
- Molecular Biology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Tropical Medicine & Parasitology (AREA)
- Medicinal Chemistry (AREA)
- Communicable Diseases (AREA)
- AIDS & HIV (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PCT/IN2010/000339 WO2011145099A1 (en) | 2010-05-20 | 2010-05-20 | Crystalline hydrochloride salt of darunavir |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| PT2571355T true PT2571355T (pt) | 2016-10-17 |
Family
ID=44991256
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PT108516964T PT2571355T (pt) | 2010-05-20 | 2010-05-20 | Sal de cloridrato cristalino de darunavir |
Country Status (6)
| Country | Link |
|---|---|
| US (2) | US8853430B2 (pt) |
| EP (1) | EP2571355B1 (pt) |
| CA (1) | CA2799762C (pt) |
| ES (1) | ES2595235T3 (pt) |
| PT (1) | PT2571355T (pt) |
| WO (1) | WO2011145099A1 (pt) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| PT2513116E (pt) | 2009-12-16 | 2015-10-14 | Hetero Research Foundation | Polimorfos de darunavir |
| ES2595235T3 (es) | 2010-05-20 | 2016-12-28 | Hetero Research Foundation | Sal clorhidrato cristalina de darunavir |
| CN103509031B (zh) * | 2012-06-20 | 2016-04-27 | 上海迪赛诺药业有限公司 | 制备达芦那韦无定形物的方法 |
| WO2013189049A1 (zh) * | 2012-06-20 | 2013-12-27 | 上海迪赛诺药业有限公司 | 制备达芦那韦无定形物的方法 |
| ES2848216T3 (es) | 2012-07-24 | 2021-08-05 | Laurus Labs Ltd | Un proceso para la preparación de Darunavir |
| CN106854212A (zh) * | 2015-12-08 | 2017-06-16 | 浙江九洲药业股份有限公司 | 一种达芦那韦无定型的制备方法 |
| EP3532478B1 (en) | 2016-10-27 | 2021-05-26 | Gilead Sciences, Inc. | Crystalline form of darunavir free base |
Family Cites Families (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NL7310889A (pt) * | 1972-08-12 | 1974-02-14 | ||
| US4670578A (en) | 1983-08-29 | 1987-06-02 | Merck & Co., Inc. | Process for crystalline salts of L or (S)-3-(3,4-dihydroxyphenyl)-2-methylalanine esters |
| US4692438A (en) | 1984-08-24 | 1987-09-08 | Hoffmann-La Roche Inc. | Pyridazo-diazepines, diazocines, and -triazepines having anti-hypertensive activity |
| US5968942A (en) * | 1992-08-25 | 1999-10-19 | G. D. Searle & Co. | α- and β-amino acid hydroxyethylamino sulfonamides useful as retroviral protease inhibitors |
| US5315016A (en) | 1992-10-13 | 1994-05-24 | Nycomed Dak A/S | Process for preparing pure podophyllotoxin |
| EP0715618B1 (en) | 1993-08-24 | 1998-12-16 | G.D. Searle & Co. | Hydroxyethylamino sulphonamides useful as retroviral protease inhibitors |
| JP4776775B2 (ja) | 1998-06-23 | 2011-09-21 | アメリカ合衆国 | Ｈｉｖ感染哺乳動物を治療するための医薬組成物 |
| US20030125336A1 (en) * | 2001-05-30 | 2003-07-03 | Fleitz Fred J. | Hydrohalide salts of an HIV protease inhibitor |
| ES2638412T3 (es) | 2002-05-16 | 2017-10-20 | Janssen Sciences Ireland Uc | Formas pseudopolimórficas de un inhibidor de la proteasa del HIV |
| WO2004002472A1 (en) | 2002-06-27 | 2004-01-08 | Sb Pharmco Puerto Rico Inc. | Carvedilol hydrobromide |
| RU2448099C2 (ru) | 2004-12-02 | 2012-04-20 | Дайити Санкё Компани, Лимитед | 7-членные циклические соединения, способы их получения и их фармацевтическое применение |
| WO2006067795A2 (en) | 2004-12-23 | 2006-06-29 | Jubilant Organosys Limited | Novel polymorphic forms of atorvastatin lactone and process for preparing the same |
| WO2007054969A2 (en) | 2005-09-21 | 2007-05-18 | Torrent Pharmaceuticals Limited | Process for the preparation of lercanidipine and amorphous form of lercanidipine hydrochloride |
| AR057182A1 (es) * | 2005-11-28 | 2007-11-21 | Tibotec Pharm Ltd | Compuestos de aminofenilsulfonamida sustituida como inhibidores de proteasa del vih |
| CA2669014C (en) * | 2006-11-09 | 2016-01-26 | Tibotec Pharmaceuticals Ltd. | Methods for the preparation of hexahydrofuro[2,3-b]furan-3-ol |
| US8921415B2 (en) * | 2009-01-29 | 2014-12-30 | Mapi Pharma Ltd. | Polymorphs of darunavir |
| EP2381786B1 (en) | 2009-01-29 | 2014-12-24 | Mapi Pharma Limited | Dimethylsulfoxide solvate of darunavir |
| KR20120006047A (ko) | 2009-04-09 | 2012-01-17 | 산도즈 아게 | 삭사글립틴의 결정 형태 |
| PT2513116E (pt) | 2009-12-16 | 2015-10-14 | Hetero Research Foundation | Polimorfos de darunavir |
| ES2595235T3 (es) | 2010-05-20 | 2016-12-28 | Hetero Research Foundation | Sal clorhidrato cristalina de darunavir |
-
2010
- 2010-05-20 ES ES10851696.4T patent/ES2595235T3/es active Active
- 2010-05-20 WO PCT/IN2010/000339 patent/WO2011145099A1/en active Application Filing
- 2010-05-20 EP EP10851696.4A patent/EP2571355B1/en active Active
- 2010-05-20 PT PT108516964T patent/PT2571355T/pt unknown
- 2010-05-20 US US13/699,096 patent/US8853430B2/en active Active
- 2010-05-20 CA CA2799762A patent/CA2799762C/en active Active
-
2014
- 2014-07-08 US US14/325,869 patent/US9175005B2/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| EP2571355A4 (en) | 2014-07-30 |
| EP2571355A1 (en) | 2013-03-27 |
| US20150080589A1 (en) | 2015-03-19 |
| US9175005B2 (en) | 2015-11-03 |
| WO2011145099A1 (en) | 2011-11-24 |
| EP2571355B1 (en) | 2016-09-07 |
| US8853430B2 (en) | 2014-10-07 |
| US20130072552A1 (en) | 2013-03-21 |
| CA2799762C (en) | 2018-03-06 |
| CA2799762A1 (en) | 2011-11-24 |
| ES2595235T3 (es) | 2016-12-28 |
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