EP2451816A4 - Crystalline form of prasugrel hydrobromide, preparation and application thereof - Google Patents

Crystalline form of prasugrel hydrobromide, preparation and application thereof

Info

Publication number
EP2451816A4
EP2451816A4 EP10796816A EP10796816A EP2451816A4 EP 2451816 A4 EP2451816 A4 EP 2451816A4 EP 10796816 A EP10796816 A EP 10796816A EP 10796816 A EP10796816 A EP 10796816A EP 2451816 A4 EP2451816 A4 EP 2451816A4
Authority
EP
European Patent Office
Prior art keywords
preparation
application
crystalline form
prasugrel hydrobromide
prasugrel
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP10796816A
Other languages
German (de)
French (fr)
Other versions
EP2451816A1 (en
Inventor
Srinivas Sanikommu Reddy
Shankar Sanganabhatla
Antyakula Pydi Bhaskar Rao
Mubeen Ahmed Khan
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Glenmark Generics Ltd
Original Assignee
Glenmark Generics Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glenmark Generics Ltd filed Critical Glenmark Generics Ltd
Publication of EP2451816A1 publication Critical patent/EP2451816A1/en
Publication of EP2451816A4 publication Critical patent/EP2451816A4/en
Withdrawn legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/4365—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system having sulfur as a ring hetero atom, e.g. ticlopidine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04—Ortho-condensed systems
EP10796816A 2009-07-06 2010-06-25 Crystalline form of prasugrel hydrobromide, preparation and application thereof Withdrawn EP2451816A4 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IN1596MU2009 2009-07-06
PCT/IN2010/000435 WO2011004392A1 (en) 2009-07-06 2010-06-25 Crystalline form of prasugrel hydrobromide, preparation and application thereof

Publications (2)

Publication Number Publication Date
EP2451816A1 EP2451816A1 (en) 2012-05-16
EP2451816A4 true EP2451816A4 (en) 2013-02-27

Family

ID=43428854

Family Applications (1)

Application Number Title Priority Date Filing Date
EP10796816A Withdrawn EP2451816A4 (en) 2009-07-06 2010-06-25 Crystalline form of prasugrel hydrobromide, preparation and application thereof

Country Status (2)

Country Link
EP (1) EP2451816A4 (en)
WO (1) WO2011004392A1 (en)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PL2398468T3 (en) 2009-02-17 2017-06-30 Krka, D.D., Novo Mesto Pharmaceutical compositions comprising prasugrel base or its pharmaceutically acceptable acid addition salts and processes for their preparation
JP5501438B2 (en) * 2009-03-31 2014-05-21 上海医薬工業研究院 Prasugrel hydrobromide crystals
EP2360159A1 (en) * 2010-02-11 2011-08-24 Ratiopharm GmbH Prasugrel in micronized, crystalline form and pharmaceutical compound of same
KR20120052381A (en) * 2010-04-08 2012-05-23 테바 파마슈티컬 인더스트리즈 리미티드 Crystalline forms of prasugrel salts
CZ305314B6 (en) * 2010-12-30 2015-07-29 Zentiva, K.S. Novel hydrobromide of the C 5-[2-cyclopropyl-1-(2-fluorophenyl)-2-oxoethyl]-4,5,6,7-tetrahydrothieno[3,2-c]pyridin-2-yl acetate form known under unprotected name prasugrel and process for preparing thereof
CN102746318A (en) * 2011-04-20 2012-10-24 上海信谊药厂有限公司 Method for preparation of Prasugrel hydrochloride
CN103102356B (en) * 2011-11-11 2016-01-27 山东新时代药业有限公司 A kind of preparation method of prasugrel hydrobromide
CZ2011872A3 (en) * 2011-12-22 2013-07-03 Zentiva, K.S. Pharmaceutical formulation of prasugrel hydrobromide
US8603537B2 (en) 2012-04-02 2013-12-10 Egis Pharmaceuticals Plc Prasugrel containing quickly released stable oral pharmaceutical compositions
CN103012427B (en) * 2012-11-26 2015-07-08 天津大学 Prasugrel hydrochloride ethanol solvate and preparation method thereof
CN103232446B (en) * 2013-05-17 2015-09-23 天津药物研究院 Yi Zhong oxazolidinone derivative crystal form II and its production and use
EP3106151A1 (en) 2015-06-19 2016-12-21 Sanovel Ilac Sanayi ve Ticaret A.S. Pharmaceutical compositions of prasugrel hydrobromide

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2011057593A2 (en) * 2009-11-16 2011-05-19 Zentiva, K.S. New salts of prasugrel and a method of their production

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PL208386B1 (en) * 2000-07-06 2011-04-29 Daiichi Sankyo Company Hydropyridine derivative acid addition salts
TWI392681B (en) * 2006-04-06 2013-04-11 Daiichi Sankyo Co Ltd Prasugrel with high purity and a method for preparing its acid addition salt
CN101255169B (en) * 2008-03-26 2010-11-10 山东大学 Prasugrel salt and preparation method thereof

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2011057593A2 (en) * 2009-11-16 2011-05-19 Zentiva, K.S. New salts of prasugrel and a method of their production

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
See also references of WO2011004392A1 *

Also Published As

Publication number Publication date
WO2011004392A1 (en) 2011-01-13
EP2451816A1 (en) 2012-05-16

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