IL147972A0 - Pd-1, a receptor for b7-4 and uses therefor - Google Patents

Pd-1, a receptor for b7-4 and uses therefor

Info

Publication number
IL147972A0
IL147972A0 IL14797200A IL14797200A IL147972A0 IL 147972 A0 IL147972 A0 IL 147972A0 IL 14797200 A IL14797200 A IL 14797200A IL 14797200 A IL14797200 A IL 14797200A IL 147972 A0 IL147972 A0 IL 147972A0
Authority
IL
Israel
Prior art keywords
receptor
uses therefor
therefor
Prior art date
Application number
IL14797200A
Other languages
English (en)
Original Assignee
Dana Farber Cancer Inst Inc Ge
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=26847600&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=IL147972(A0) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Dana Farber Cancer Inst Inc Ge filed Critical Dana Farber Cancer Inst Inc Ge
Publication of IL147972A0 publication Critical patent/IL147972A0/xx

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70503—Immunoglobulin superfamily
    • C07K14/70532—B7 molecules, e.g. CD80, CD86
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70503—Immunoglobulin superfamily
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2803—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2803—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
    • C07K16/2827—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against B7 molecules, e.g. CD80, CD86
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    • A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/21—Immunoglobulins specific features characterized by taxonomic origin from primates, e.g. man
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/60—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments
    • C07K2317/62—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments comprising only variable region components
    • C07K2317/622—Single chain antibody (scFv)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/73—Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/74—Inducing cell proliferation
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/30—Non-immunoglobulin-derived peptide or protein having an immunoglobulin constant or Fc region, or a fragment thereof, attached thereto
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00—Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/705—Assays involving receptors, cell surface antigens or cell surface determinants
    • G01N2333/70503—Immunoglobulin superfamily, e.g. VCAMs, PECAM, LFA-3
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2500/00—Screening for compounds of potential therapeutic value
    • G01N2500/04—Screening involving studying the effect of compounds C directly on molecule A (e.g. C are potential ligands for a receptor A, or potential substrates for an enzyme A)

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Virology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Cell Biology (AREA)
  • Epidemiology (AREA)
  • Zoology (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Pulmonology (AREA)
  • Diabetes (AREA)
  • Neurosurgery (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Rheumatology (AREA)
IL14797200A 1999-08-23 2000-08-23 Pd-1, a receptor for b7-4 and uses therefor IL147972A0 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US15039099P 1999-08-23 1999-08-23
US16489799P 1999-11-10 1999-11-10
PCT/US2000/023347 WO2001014557A1 (fr) 1999-08-23 2000-08-23 Pd-1, recepteur de b7-4, et son utilisation

Publications (1)

Publication Number Publication Date
IL147972A0 true IL147972A0 (en) 2002-09-12

Family

ID=26847600

Family Applications (2)

Application Number Title Priority Date Filing Date
IL14797200A IL147972A0 (en) 1999-08-23 2000-08-23 Pd-1, a receptor for b7-4 and uses therefor
IL147972A IL147972A (en) 1999-08-23 2002-02-03 Multi-value antibodies to PD-1

Family Applications After (1)

Application Number Title Priority Date Filing Date
IL147972A IL147972A (en) 1999-08-23 2002-02-03 Multi-value antibodies to PD-1

Country Status (19)

Country Link
US (3) US6808710B1 (fr)
EP (2) EP1210428B1 (fr)
JP (6) JP4896327B2 (fr)
AU (2) AU7072700A (fr)
BR (1) BR0013581A (fr)
CA (2) CA2925551A1 (fr)
CY (3) CY2017036I1 (fr)
DK (1) DK1210428T3 (fr)
ES (1) ES2539411T3 (fr)
FR (2) FR17C1055I1 (fr)
HU (4) HU228477B1 (fr)
IL (2) IL147972A0 (fr)
LU (2) LUC00049I2 (fr)
MX (1) MXPA02001877A (fr)
NO (1) NO20020859L (fr)
NZ (1) NZ517955A (fr)
PL (1) PL354286A1 (fr)
PT (1) PT1210428E (fr)
WO (1) WO2001014557A1 (fr)

Families Citing this family (393)

* Cited by examiner, † Cited by third party
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US20080213778A1 (en) 1998-12-30 2008-09-04 Millennium Pharmaceuticals, Inc. Novel genes encoding proteins having prognostic, diagnostic, preventive, therapeutic, and other uses
US7041474B2 (en) 1998-12-30 2006-05-09 Millennium Pharmaceuticals, Inc. Nucleic acid encoding human tango 509
US6936704B1 (en) 1999-08-23 2005-08-30 Dana-Farber Cancer Institute, Inc. Nucleic acids encoding costimulatory molecule B7-4
AU7072700A (en) 1999-08-23 2001-03-19 Dana-Farber Cancer Institute, Inc. Pd-1, a receptor for b7-4, and uses therefor
WO2001039722A2 (fr) 1999-11-30 2001-06-07 Mayo Foundation For Medical Education And Research Nouvelle molecule immunoregulatrice b7-h1,
US7030219B2 (en) 2000-04-28 2006-04-18 Johns Hopkins University B7-DC, Dendritic cell co-stimulatory molecules
EP1292619B1 (fr) 2000-06-06 2008-02-06 Bristol-Myers Squibb Company Acides nucleiques et polypeptides apparentes a b7 utiles pour effectuer une immunomodulation
CA2413857C (fr) * 2000-06-28 2010-04-27 Genetics Institute, Llc. Molecules pd-l2: nouveaux ligands pour pd-1 et leurs utilisations
US6962814B2 (en) 2000-08-16 2005-11-08 Duke University Decellularized tissue engineered constructs and tissues
WO2002077208A1 (fr) * 2001-03-27 2002-10-03 Genethor Gmbh Diminution de reactions immunitaires specifiques dependante de certains antigenes par un effet de co-stimulation
CA2442066C (fr) 2001-04-02 2005-11-01 Wyeth Le pd-1, recepteur du b7-4, et ses utilisations
AR036993A1 (es) 2001-04-02 2004-10-20 Wyeth Corp Uso de agentes que modulan la interaccion entre pd-1 y sus ligandos en la submodulacion de respuestas inmunologicas
WO2002086083A2 (fr) * 2001-04-20 2002-10-31 Mayo Foundation For Medical Education And Research Procedes d'amelioration de la capacite de reaction de cellules t
WO2002092792A2 (fr) * 2001-05-16 2002-11-21 Genethor Gmbh Procede de reduction de reactions immunitaires specifiques, liee aux antigenes, consistant a agir sur la co-stimulation
US6905827B2 (en) 2001-06-08 2005-06-14 Expression Diagnostics, Inc. Methods and compositions for diagnosing or monitoring auto immune and chronic inflammatory diseases
US7235358B2 (en) * 2001-06-08 2007-06-26 Expression Diagnostics, Inc. Methods and compositions for diagnosing and monitoring transplant rejection
ATE524495T1 (de) * 2001-07-31 2011-09-15 Ono Pharmaceutical Co Pd-1-spezifische substanz
US20050089957A1 (en) * 2001-10-19 2005-04-28 Audrey Goddard Compositions and methods for the diagnosis and treatment of inflammatory bowel disorders
EP1456652A4 (fr) * 2001-11-13 2005-11-02 Dana Farber Cancer Inst Inc Agents modulant l'activite de cellules immunes et procedes d'utilisation associes
PT1565489E (pt) 2002-06-19 2011-02-23 Raven Biotechnologies Inc Anticorpos internalizantes específicos para o alvo de superfície celular raag10
FI2206517T3 (fi) 2002-07-03 2023-10-19 Ono Pharmaceutical Co Immuunopotentioivia koostumuksia käsittäen anti-PD-L1 -vasta-aineita
US7052694B2 (en) * 2002-07-16 2006-05-30 Mayo Foundation For Medical Education And Research Dendritic cell potentiation
ATE514713T1 (de) * 2002-12-23 2011-07-15 Wyeth Llc Antikörper gegen pd-1 und ihre verwendung
EP1591527B1 (fr) 2003-01-23 2015-08-26 Ono Pharmaceutical Co., Ltd. Substance specifique a pd-1 humain
GB0400440D0 (en) * 2004-01-09 2004-02-11 Isis Innovation Receptor modulators
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CY2017036I2 (el) 2018-04-04
US6808710B1 (en) 2004-10-26
CY2019016I1 (el) 2019-11-27
NO20020859D0 (no) 2002-02-22
AU2005234733A1 (en) 2005-12-15
HUS1700045I1 (hu) 2017-12-28
NO20020859L (no) 2002-04-22
JP2016166173A (ja) 2016-09-15
BR0013581A (pt) 2002-07-02
HUP0202449A2 (en) 2002-10-28
CA2925551A1 (fr) 2001-03-01
FR19C1019I1 (fr) 2019-05-03
EP1210428B1 (fr) 2015-03-18
IL147972A (en) 2013-04-30
HU228477B1 (en) 2013-03-28
CA2383456C (fr) 2016-06-07
CY2019016I2 (el) 2019-11-27
JP2014040419A (ja) 2014-03-06
AU7072700A (en) 2001-03-19
LUC00052I1 (fr) 2017-11-30
DK1210428T3 (en) 2015-06-15
PT1210428E (pt) 2015-07-21
US7638492B2 (en) 2009-12-29
LUC00049I1 (fr) 2017-11-17
JP2011105751A (ja) 2011-06-02
FR17C1055I1 (fr) 2018-01-12
CA2383456A1 (fr) 2001-03-01
AU2005234733B2 (en) 2008-07-03
HUP0202449A3 (en) 2010-01-28
EP2360254A1 (fr) 2011-08-24
CY2017036I1 (el) 2018-04-04
LUC00052I2 (fr) 2018-02-26
JP4896327B2 (ja) 2012-03-14
WO2001014557A1 (fr) 2001-03-01
US7101550B2 (en) 2006-09-05
JP2003507491A (ja) 2003-02-25
HUS1900010I1 (hu) 2019-04-29
JP2018100291A (ja) 2018-06-28
US20020160000A1 (en) 2002-10-31
CY2017037I2 (el) 2018-04-04
JP2020028302A (ja) 2020-02-27
US20070202100A1 (en) 2007-08-30
EP1210428A1 (fr) 2002-06-05
LUC00049I2 (fr) 2018-01-23
PL354286A1 (en) 2003-12-29
HUS1700046I1 (hu) 2018-11-28
CY2017037I1 (el) 2018-04-04

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