NZ334613A
(en)
|
1996-08-12 |
2002-02-01 |
Welfide Corp |
Pharmaceutical agents comprising Rho kinase inhibitor
|
WO1999054306A1
(fr)
*
|
1997-03-10 |
1999-10-28 |
Hiroyoshi Hidaka |
Derives isoquinolinesulfonamide et medicaments integrant ces derives comme principe actif
|
US20080233098A1
(en)
*
|
1997-10-31 |
2008-09-25 |
Mckerracher Lisa |
RHO Family Antagonists and Their Use to Block Inhibition of Neurite Outgrowth
|
DE69927936T2
(de)
*
|
1998-08-17 |
2006-06-29 |
Mitsubishi Pharma Corp. |
Präventiva/mittel zur glaukombehandlung
|
US7169783B2
(en)
|
1998-11-02 |
2007-01-30 |
Universite De Montreal |
(+)-Trans-4-(1-aminoethyl)-1-(4-pyridycarbamoyl)-cyclohexane and method for promoting neural growth in the central nervous system and in a patient at a site of neuronal lesion
|
WO2000057914A1
(fr)
*
|
1999-03-25 |
2000-10-05 |
Santen Pharmaceutical Co., Ltd. |
Agents permettant d'abaisser la tension oculaire
|
US6844354B1
(en)
|
1999-03-25 |
2005-01-18 |
Mitsubishi Pharma Corporation |
Agent for prophylaxis and treatment of interstitial pneumonia and pulmonary fibrosis
|
CA2369552A1
(en)
*
|
1999-04-22 |
2000-11-02 |
Hisashi Kai |
Agent for prophylaxis and treatment of angiostenosis
|
KR100812972B1
(ko)
*
|
1999-04-27 |
2008-03-13 |
미쯔비시 웰 파마 가부시키가이샤 |
간질환 예방/치료제
|
WO2000078351A1
(fr)
*
|
1999-06-18 |
2000-12-28 |
Mitsubishi Pharma Corporation |
Promoteurs de l'osteogenese
|
JP2001081031A
(ja)
*
|
1999-08-30 |
2001-03-27 |
Schering Ag |
溶解性および経口吸収性を改善したベンズアミド誘導体含有製剤
|
AU6865100A
(en)
*
|
1999-09-02 |
2001-04-10 |
Mitsubishi Pharma Corporation |
Osteogenesis promoting agents
|
WO2001022997A1
(fr)
*
|
1999-09-29 |
2001-04-05 |
Mitsubishi Pharma Corporation |
Analgesiques
|
US7217722B2
(en)
|
2000-02-01 |
2007-05-15 |
Kirin Beer Kabushiki Kaisha |
Nitrogen-containing compounds having kinase inhibitory activity and drugs containing the same
|
CA2403321C
(en)
*
|
2000-03-16 |
2009-07-14 |
Mitsubishi Pharma Corporation |
Amide compounds and use thereof
|
JP4776138B2
(ja)
*
|
2000-03-31 |
2011-09-21 |
田辺三菱製薬株式会社 |
腎臓疾患予防・治療剤
|
AU2001274598A1
(en)
|
2000-06-23 |
2002-01-02 |
Mitsubishi Pharma Corporation |
Antitumor effect potentiators
|
MXPA03002410A
(es)
*
|
2000-09-20 |
2003-06-19 |
Merck Patent Gmbh |
4-amino-quinazolinas.
|
CA2422560A1
(en)
*
|
2000-09-20 |
2002-03-28 |
Merck Patent Gesellschaft Mit Beschraenkter Haftung |
4-amino-quinazolines
|
JP4582561B2
(ja)
*
|
2000-10-23 |
2010-11-17 |
旭化成ファーマ株式会社 |
移植による血管病変の発生抑制剤
|
JP2002139493A
(ja)
*
|
2000-11-01 |
2002-05-17 |
Sumitomo Pharmaceut Co Ltd |
新規なハイスループット・スクリーニング方法
|
CA2325842C
(en)
*
|
2000-11-02 |
2007-08-07 |
Lisa Mckerracher |
Methods for making and delivering rho-antagonist tissue adhesive formulations to the injured mammalian central and peripheral nervous systems and uses thereof
|
US20020177207A1
(en)
*
|
2001-03-14 |
2002-11-28 |
Myriad Genetics, Incorporated |
Tsg101-interacting proteins and use thereof
|
WO2002053143A2
(en)
*
|
2001-01-05 |
2002-07-11 |
The Medical College Of Georgia Research Institute, Inc. |
Treatment of erectile dysfunction with rho-kinase inhibitors
|
JP2002226375A
(ja)
*
|
2001-01-31 |
2002-08-14 |
Asahi Kasei Corp |
線維化予防、治療剤
|
US20030068320A1
(en)
*
|
2001-03-02 |
2003-04-10 |
Christine Dingivan |
Methods of administering/dosing CD2 antagonists for the prevention and treatment of autoimmune disorders or inflammatory disorders
|
DE60211317T2
(de)
*
|
2001-03-23 |
2007-04-12 |
Bayer Corp. |
Rho-kinase inhibitoren
|
DK1370552T3
(da)
*
|
2001-03-23 |
2007-05-07 |
Bayer Pharmaceuticals Corp |
Rho-kinase-inhibitorer
|
CN101310771B
(zh)
*
|
2001-04-11 |
2012-08-08 |
千寿制药株式会社 |
视觉功能障碍改善剂
|
US7442686B2
(en)
|
2001-04-12 |
2008-10-28 |
Bioaxone Therapeutique Inc. |
Treatment of macular degeneration with ADP-ribosyl transferase fusion protein therapeutic compositions
|
WO2002100833A1
(fr)
*
|
2001-06-12 |
2002-12-19 |
Sumitomo Pharmaceuticals Company, Limited |
Inhibiteurs de rho kinase
|
JP5042419B2
(ja)
*
|
2001-08-15 |
2012-10-03 |
旭化成ファーマ株式会社 |
骨形成促進剤および骨形成促進組成物
|
US7829566B2
(en)
*
|
2001-09-17 |
2010-11-09 |
Werner Mederski |
4-amino-quinazolines
|
DE10153605A1
(de)
*
|
2001-11-02 |
2003-05-28 |
Morphochem Ag Komb Chemie |
Verwendung von Inhibitoren der Rho-Kinasen zur Stimulation des Nervenwachstums, zur Inhibition der Narbengewebsbildung und/oder Reduktion eines Sekundärschadens
|
WO2003047591A1
(en)
*
|
2001-11-30 |
2003-06-12 |
Asahi Kasei Pharma Corporation |
Remedies for primary pulmonary hypertension
|
FR2833840B1
(fr)
*
|
2001-12-21 |
2010-06-18 |
Rytek |
Methodes et compositions pour le traitement de pathologies respiratoires
|
DE60320933D1
(de)
*
|
2002-01-10 |
2008-06-26 |
Bayer Healthcare Ag |
Rho-kinase inhibitoren
|
WO2003062227A1
(en)
*
|
2002-01-23 |
2003-07-31 |
Bayer Pharmaceuticals Corporation |
Rho-kinase inhibitors
|
MXPA04007191A
(es)
*
|
2002-01-23 |
2005-03-31 |
Bayer Pharmaceuticals Corp |
Derivados de pirimidina como inhibidores de rho-quinasa.
|
US7645878B2
(en)
*
|
2002-03-22 |
2010-01-12 |
Bayer Healthcare Llc |
Process for preparing quinazoline Rho-kinase inhibitors and intermediates thereof
|
GB0206860D0
(en)
*
|
2002-03-22 |
2002-05-01 |
Glaxo Group Ltd |
Compounds
|
WO2003082808A1
(fr)
*
|
2002-04-03 |
2003-10-09 |
Sumitomo Pharmaceuticals Company, Limited. |
Derives de benzamide
|
US7425618B2
(en)
|
2002-06-14 |
2008-09-16 |
Medimmune, Inc. |
Stabilized anti-respiratory syncytial virus (RSV) antibody formulations
|
US20040028716A1
(en)
*
|
2002-06-14 |
2004-02-12 |
Marks Andrew R. |
Use of Y-27632 as an agent to prevent restenosis after coronary artery angioplasty/stent implantation
|
US7132100B2
(en)
|
2002-06-14 |
2006-11-07 |
Medimmune, Inc. |
Stabilized liquid anti-RSV antibody formulations
|
CN1681525A
(zh)
*
|
2002-07-12 |
2005-10-12 |
曹义海 |
一种抑制血管渗漏和组织水肿的方法
|
JPWO2004009555A1
(ja)
*
|
2002-07-22 |
2005-11-17 |
旭化成ファーマ株式会社 |
5−置換イソキノリン誘導体
|
US7094789B2
(en)
|
2002-07-22 |
2006-08-22 |
Asahi Kasei Pharma Corporation |
5-substituted isoquinoline derivatives
|
DE10233737A1
(de)
*
|
2002-07-24 |
2004-02-05 |
Morphochem Aktiengesellschaft für kombinatorische Chemie |
Verwendung von Modulatoren des Signaltransduktionswegs über die Proteinkinase Fyn zur Behandlung von Tumorerkrankungen
|
US20040105860A1
(en)
*
|
2002-08-01 |
2004-06-03 |
Losordo Douglas W. |
Cell modulation using a cytoskeletal protein
|
CN100425241C
(zh)
|
2002-08-29 |
2008-10-15 |
参天制药株式会社 |
由Rho激酶抑制剂和前列腺素类物质构成的青光眼治疗剂
|
CA2400996A1
(en)
*
|
2002-09-03 |
2004-03-03 |
Lisa Mckerracher |
1,4-substituted cyclohexane derivatives
|
AU2003264427A1
(en)
|
2002-09-12 |
2004-04-30 |
Kirin Beer Kabushiki Kaisha |
Isoquinoline derivatives having kinasae inhibitory activity and drugs containing the same
|
US20050215601A1
(en)
*
|
2002-09-25 |
2005-09-29 |
Santen Pharmaceutical Co., Ltd. |
Therapeutic agent for rheumatic disease comprising benzamide derivative as active ingredient
|
US7563810B2
(en)
*
|
2002-11-06 |
2009-07-21 |
Celgene Corporation |
Methods of using 3-(4-amino-1-oxo-1,3-dihydroisoindol-2-yl)-piperidine-2,6-dione for the treatment and management of myeloproliferative diseases
|
US8034831B2
(en)
*
|
2002-11-06 |
2011-10-11 |
Celgene Corporation |
Methods for the treatment and management of myeloproliferative diseases using 4-(amino)-2-(2,6-Dioxo(3-piperidyl)-isoindoline-1,3-dione in combination with other therapies
|
AU2003280812A1
(en)
*
|
2002-11-18 |
2004-06-15 |
Santen Pharmaceutical Co., Ltd. |
REMEDY FOR GLAUCOMA COMPRISING Rho KINASE INHIBITOR AND Beta-BLOCKER
|
AU2003901270A0
(en)
*
|
2003-03-18 |
2003-04-03 |
Medvet Science Pty. Ltd. |
A method of modulating muscle cell functioning
|
AU2004221792C1
(en)
*
|
2003-03-18 |
2009-09-24 |
Medvet Science Pty. Ltd. |
A method of modulating smooth muscle cell functioning by modulating sphingosine kinase mediated signalling
|
GB2400316A
(en)
*
|
2003-04-10 |
2004-10-13 |
Richard Markoll |
Electromagnetic stimulation in patients with osteoporosis
|
EP1613273B1
(en)
|
2003-04-11 |
2012-06-13 |
MedImmune, LLC |
Recombinant il-9 antibodies and uses thereof
|
PL1616577T3
(pl)
|
2003-04-18 |
2012-02-29 |
Senju Pharma Co |
2-chloro-6,7-dimetoksy-N-5 [5-(1)H-indazolilo]chinazolino-4-amina, dichlorowodorek N-(1-benzylo-4-piperydynylo)- 1H-indazolo-5-aminy, kwas 4-[2-(2,3,4,5,6-pentafluorofenylo)akryloilo] cynamonowy i chlorowodorek fasudilu do zastosowania w naprawianiu percepcji rogówki
|
WO2004105757A2
(en)
*
|
2003-05-29 |
2004-12-09 |
Schering Aktiengesellschaft |
Use of rho-kinase inhibitors in the treatment of aneurysm and cardiac hypertrophy
|
US20110098232A1
(en)
*
|
2003-05-30 |
2011-04-28 |
Zeilig Charles E |
Methods For The Selective Treatment Of Tumors By Calcium-Mediated Induction Of Apoptosis
|
WO2004108142A2
(en)
*
|
2003-06-06 |
2004-12-16 |
The University Of Manchester |
Inhibitors of tip-1 for treatment tissue damage
|
US7160894B2
(en)
|
2003-06-06 |
2007-01-09 |
Asahi Kasei Pharma Corporation |
Tricyclic compound
|
US7417026B2
(en)
*
|
2003-08-13 |
2008-08-26 |
Children's Hospital Medical Center |
Mobilization of hematopoietic cells
|
JP2007535479A
(ja)
*
|
2003-08-13 |
2007-12-06 |
チルドレンズ ホスピタル メディカル センター |
GTPaseを調節するためのキメラペプチド
|
AU2004286198C1
(en)
|
2003-08-18 |
2011-02-24 |
Medimmune, Llc |
Humanization of antibodies
|
US20060228350A1
(en)
*
|
2003-08-18 |
2006-10-12 |
Medimmune, Inc. |
Framework-shuffling of antibodies
|
US7371850B1
(en)
|
2003-08-20 |
2008-05-13 |
Myriad Genetics, Inc. |
Method and composition for reducing expression of ROCK-II
|
KR101163800B1
(ko)
|
2003-10-15 |
2012-07-09 |
산텐 세이야꾸 가부시키가이샤 |
신규 인다졸 유도체
|
US20050238666A1
(en)
*
|
2003-12-05 |
2005-10-27 |
Williams David A |
Methods of enhancing stem cell engraftment
|
DK1696920T3
(en)
|
2003-12-19 |
2015-01-19 |
Plexxikon Inc |
RELATIONS AND PROCEDURES FOR THE DEVELOPMENT OF LAW MODULATORS
|
PT1696958E
(pt)
*
|
2003-12-22 |
2007-06-04 |
Alcon Inc |
Agentes para o tratamento de retinopatia glaucomatosa e neuropatia óptica .
|
TW200526224A
(en)
*
|
2003-12-22 |
2005-08-16 |
Alcon Inc |
Short form c-Maf transcription factor antagonists for treatment of glaucoma
|
JP2007515422A
(ja)
*
|
2003-12-22 |
2007-06-14 |
アルコン,インコーポレイテッド |
糖尿病性網膜症および黄斑変性における結晶腔形成の処置のための薬剤
|
CN1980929A
(zh)
*
|
2004-02-24 |
2007-06-13 |
比奥阿克松医疗技术股份有限公司 |
4-取代哌啶衍生物
|
WO2005094824A1
(en)
*
|
2004-03-25 |
2005-10-13 |
East Carolina University |
Methods of enhancing cancer therapy by protecting nerve cells
|
US20080096238A1
(en)
*
|
2004-03-30 |
2008-04-24 |
Alcon, Inc. |
High throughput assay for human rho kinase activity with enhanced signal-to-noise ratio
|
US20060115870A1
(en)
*
|
2004-03-30 |
2006-06-01 |
Alcon, Inc. |
High throughput assay for human Rho kinase activity
|
WO2005102345A1
(en)
*
|
2004-03-30 |
2005-11-03 |
Alcon, Inc. |
Use of rho kinase inhibitors in the treatment of hearing loss, tinnitus and improving body balance
|
AU2005229015C1
(en)
|
2004-04-02 |
2013-01-17 |
The Regents Of The University Of California |
Methods and compositions for treating and preventing disease associated with alphaVbeta5 integrin
|
CN1795196B
(zh)
*
|
2004-06-03 |
2013-07-24 |
千寿制药株式会社 |
酰胺化合物在制备用于修复角膜敏感性的药剂中的应用
|
EP1809326A4
(en)
|
2004-10-27 |
2009-11-04 |
Medimmune Inc |
MODULATION OF ANTIBODY SPECIFICITY BY MEASURING ADAPTATION OF ITS AFFINITY TO AN APPARENT ANTIGEN
|
FR2879100B1
(fr)
|
2004-12-09 |
2007-07-06 |
Lionel Bueno |
Compositions pour le traitement des pathologies oculaires de surface et de la retine
|
AR054416A1
(es)
*
|
2004-12-22 |
2007-06-27 |
Incyte Corp |
Pirrolo [2,3-b]piridin-4-il-aminas y pirrolo [2,3-b]pirimidin-4-il-aminas como inhibidores de las quinasas janus. composiciones farmaceuticas.
|
ZA200704959B
(en)
*
|
2004-12-27 |
2009-04-29 |
Alcon Inc |
Aminopyrazine analogs for treating glaucoma and other rho kinase-mediated diseases
|
US20090029970A1
(en)
*
|
2005-02-16 |
2009-01-29 |
Astellas Pharma Inc. |
Pain remedy containing rock inhibitor
|
EP1869192B1
(en)
|
2005-03-18 |
2016-01-20 |
MedImmune, LLC |
Framework-shuffling of antibodies
|
CR9465A
(es)
|
2005-03-25 |
2008-06-19 |
Surface Logix Inc |
Compuestos mejorados farmacocineticamente
|
WO2007002543A2
(en)
|
2005-06-23 |
2007-01-04 |
Medimmune, Inc. |
Antibody formulations having optimized aggregation and fragmentation profiles
|
CA2611295C
(en)
|
2005-06-28 |
2014-04-22 |
Sanofi-Aventis |
Isoquinoline derivatives as inhibitors of rho-kinase
|
EP1912949B1
(en)
|
2005-07-26 |
2011-08-24 |
Sanofi |
Cyclohexylamin isoquinolone derivatives as rho-kinase inhibitors
|
CA2615577C
(en)
|
2005-07-26 |
2014-09-09 |
Sanofi-Aventis |
Piperidinyl-substituted isoquinolone derivatives as rho-kinase inhibitors
|
EP1928437A2
(en)
|
2005-08-26 |
2008-06-11 |
Braincells, Inc. |
Neurogenesis by muscarinic receptor modulation
|
EP2258359A3
(en)
|
2005-08-26 |
2011-04-06 |
Braincells, Inc. |
Neurogenesis by muscarinic receptor modulation with sabcomelin
|
BRPI0614974A2
(pt)
|
2005-08-30 |
2010-12-14 |
Asahi Kasei Pharma Corp |
composto, medicamento, inibidor da fosforilaÇço da cadeia leve regulatària da miosina, inibidor da via rho/rho quinase, e, mÉtodo para tratamento terapÊutico e/ou profilÁtico de glaucoma
|
KR20080040027A
(ko)
|
2005-09-02 |
2008-05-07 |
아스테라스 세이야쿠 가부시키가이샤 |
Rock 억제제로서 아미드 유도체
|
CA2625153A1
(en)
|
2005-10-21 |
2007-04-26 |
Braincells, Inc. |
Modulation of neurogenesis by pde inhibition
|
JP4832051B2
(ja)
*
|
2005-10-21 |
2011-12-07 |
学校法人順天堂 |
半月体形成性腎病変治療剤
|
WO2007050783A2
(en)
|
2005-10-26 |
2007-05-03 |
Asahi Kasei Pharma Corporation |
Fasudil in combination therapies for the treatment of pulmonary arterial hypertension
|
AU2006308889A1
(en)
|
2005-10-31 |
2007-05-10 |
Braincells, Inc. |
GABA receptor mediated modulation of neurogenesis
|
US7867999B1
(en)
|
2005-12-22 |
2011-01-11 |
Alcon Research, Ltd. |
Hydroxyamino- and amino-substituted pyridine analogs for treating rho kinase-mediated diseases and conditions
|
CN101340912A
(zh)
*
|
2005-12-22 |
2009-01-07 |
爱尔康研究有限公司 |
用于治疗rho激酶介导的疾病和病状的(吲唑-5-基)-吡嗪和(1,3-二氢-吲哚-2-酮)-吡嗪
|
US20100216734A1
(en)
|
2006-03-08 |
2010-08-26 |
Braincells, Inc. |
Modulation of neurogenesis by nootropic agents
|
WO2007134077A2
(en)
|
2006-05-09 |
2007-11-22 |
Braincells, Inc. |
5 ht receptor mediated neurogenesis
|
EP2382975A3
(en)
|
2006-05-09 |
2012-02-29 |
Braincells, Inc. |
Neurogenesis by modulating angiotensin
|
JPWO2007142323A1
(ja)
|
2006-06-08 |
2009-10-29 |
宇部興産株式会社 |
側鎖にスピロ環構造を有する新規インダゾール誘導体
|
JPWO2008016016A1
(ja)
*
|
2006-07-31 |
2009-12-24 |
千寿製薬株式会社 |
アミド化合物を含有する水性液剤
|
WO2008022182A1
(en)
*
|
2006-08-16 |
2008-02-21 |
The Uab Research Foundation |
Methods for promoting coupling between bone formation and resorption
|
TW201343676A
(zh)
|
2006-08-28 |
2013-11-01 |
Kyowa Hakko Kirin Co Ltd |
具拮抗性之人類light專一性人類單株抗體
|
GB0617222D0
(en)
*
|
2006-08-31 |
2006-10-11 |
Vereniging Het Nl Kanker I |
Antibiotics
|
MX2009002496A
(es)
|
2006-09-08 |
2009-07-10 |
Braincells Inc |
Combinaciones que contienen un derivado de 4-acilaminopiridina.
|
US20100184806A1
(en)
|
2006-09-19 |
2010-07-22 |
Braincells, Inc. |
Modulation of neurogenesis by ppar agents
|
WO2008049000A2
(en)
*
|
2006-10-18 |
2008-04-24 |
United Therapeutics Corporation |
Combination therapy for pulmonary arterial hypertension
|
WO2008063888A2
(en)
|
2006-11-22 |
2008-05-29 |
Plexxikon, Inc. |
Compounds modulating c-fms and/or c-kit activity and uses therefor
|
WO2008079945A2
(en)
*
|
2006-12-20 |
2008-07-03 |
University Of South Florida |
Rock inhibitors and uses thereof
|
AR064420A1
(es)
*
|
2006-12-21 |
2009-04-01 |
Alcon Mfg Ltd |
Composiciones farmaceuticas oftalmicas que comprenden una cantidad efectiva de analogos de 6-aminoimidazo[1,2b]piridazinas, utiles para el tratamiento del glaucoma y/o controlar la presion intraocular normal o elevada(iop).
|
AU2007338406B2
(en)
|
2006-12-27 |
2012-08-09 |
Sanofi-Aventis |
Substituted isoquinoline and isoquinolinone derivatives as inhibitors of Rho-kinase
|
WO2008077551A1
(en)
|
2006-12-27 |
2008-07-03 |
Sanofi-Aventis |
Cycloalkylamine substituted isoquinolone derivatives
|
ES2363105T3
(es)
|
2006-12-27 |
2011-07-20 |
Sanofi-Aventis |
Isoquinolinas sustituidas y su uso como inhibidores de rho-quinasa.
|
MX2009006517A
(es)
|
2006-12-27 |
2009-06-26 |
Sanofi Aventis |
Nuevos derivados de isoquinolina e isoquinolinona sustituidos.
|
WO2008077554A1
(en)
|
2006-12-27 |
2008-07-03 |
Sanofi-Aventis |
Cycloalkylamine substituted isoquinoline derivatives
|
CN101578266B
(zh)
|
2006-12-27 |
2013-10-30 |
塞诺菲-安万特股份有限公司 |
环烷基胺取代的异喹啉和异喹啉酮衍生物
|
US7892830B2
(en)
*
|
2007-01-17 |
2011-02-22 |
Wisconsin Alumni Research Foundation |
Clonal culture of human pluripotent stem cells
|
US8415372B2
(en)
|
2007-02-27 |
2013-04-09 |
Asahi Kasei Pharma Corporation |
Sulfonamide compound
|
CN101622243B
(zh)
|
2007-02-28 |
2013-12-04 |
旭化成制药株式会社 |
磺酰胺衍生物
|
KR101566171B1
(ko)
|
2007-03-09 |
2015-11-06 |
삼성전자 주식회사 |
디지털 저작권 관리 방법 및 장치
|
EP2703007A1
(en)
|
2007-03-30 |
2014-03-05 |
MedImmune, LLC |
Antibodies with decreased deamidation profiles
|
US20100099640A1
(en)
*
|
2007-05-04 |
2010-04-22 |
Joannes Geuns |
Tissue degeneration protection
|
KR101246392B1
(ko)
|
2007-07-02 |
2013-03-21 |
아사히 가세이 파마 가부시키가이샤 |
술폰아미드 화합물 및 그 결정
|
MX2010000617A
(es)
|
2007-07-17 |
2010-05-17 |
Plexxikon Inc |
Compuestos y metodos para modulacion de cinasa, e indicaciones de estos.
|
KR20210070407A
(ko)
*
|
2007-08-29 |
2021-06-14 |
센주 세이야꾸 가부시키가이샤 |
각막 내피 세포 접착 촉진제
|
WO2009140200A1
(en)
*
|
2008-05-12 |
2009-11-19 |
Amnestix, Inc. |
Compounds for improving learning and memory
|
SI2303845T1
(sl)
|
2008-06-24 |
2013-12-31 |
Sanofi |
Bi- in policiklični substituirani izokinolin in izokinolinski derivati kot inhibitorji rho-kinaze
|
NZ590070A
(en)
|
2008-06-24 |
2012-02-24 |
Sanofi Aventis |
Substituted isoquinolines and isoquinolinones as rho kinase inhibitors
|
BRPI0914735A2
(pt)
|
2008-06-24 |
2019-09-24 |
Sanofi Aventis |
isoquinolinas e isoquinolinonas 6-substituídas
|
WO2010010702A1
(ja)
|
2008-07-24 |
2010-01-28 |
国立大学法人大阪大学 |
軸性近視の予防または治療剤
|
EP2331507A2
(en)
*
|
2008-09-18 |
2011-06-15 |
Astellas Pharma Inc. |
Heterocyclic carboxamide compounds
|
EP2177218A1
(en)
|
2008-10-15 |
2010-04-21 |
Medizinische Universität Wien |
Regenerative therapy
|
EP2177510A1
(en)
|
2008-10-17 |
2010-04-21 |
Universität des Saarlandes |
Allosteric protein kinase modulators
|
US20100216805A1
(en)
|
2009-02-25 |
2010-08-26 |
Braincells, Inc. |
Modulation of neurogenesis using d-cycloserine combinations
|
NZ594398A
(en)
|
2009-04-03 |
2014-03-28 |
Plexxikon Inc |
Propane-1-sulfonic acid (3-[5-(4-chloro-phenyl)-1h-pyrrol [2, 3-b] pyridine-3-carbonyl]-2,4-difluoro-phenyl} -amide compositions and uses thereof
|
US8329724B2
(en)
|
2009-08-03 |
2012-12-11 |
Hoffmann-La Roche Inc. |
Process for the manufacture of pharmaceutically active compounds
|
WO2011021221A2
(en)
|
2009-08-17 |
2011-02-24 |
Reliance Life Sciences Pvt. Ltd. |
Compositions for spinal cord injury
|
ES2638464T3
(es)
|
2009-10-16 |
2017-10-20 |
The Scripps Research Institute |
Inducción de células pluripotentes
|
KR20120102669A
(ko)
|
2009-11-06 |
2012-09-18 |
플렉시콘, 인코퍼레이티드 |
키나제 조정을 위한 화합물 및 방법, 및 이를 위한 적응증
|
CN102188697B
(zh)
*
|
2010-03-03 |
2014-11-05 |
中国医学科学院药物研究所 |
重组人Rho激酶在制备药物中的应用
|
US9782454B2
(en)
|
2010-04-22 |
2017-10-10 |
Longevity Biotech, Inc. |
Highly active polypeptides and methods of making and using the same
|
KR102482184B1
(ko)
|
2010-12-22 |
2022-12-28 |
페이트 세러퓨틱스, 인코포레이티드 |
단세포 분류 및 iPSC의 증강된 재프로그래밍을 위한 세포 배양 플랫폼
|
AR085091A1
(es)
|
2011-01-26 |
2013-09-11 |
Kolltan Pharmaceuticals Inc |
Anticuerpos anti-kit y sus usos
|
US9624213B2
(en)
|
2011-02-07 |
2017-04-18 |
Plexxikon Inc. |
Compounds and methods for kinase modulation, and indications therefor
|
TWI558702B
(zh)
|
2011-02-21 |
2016-11-21 |
普雷辛肯公司 |
醫藥活性物質的固態形式
|
EP2628482A1
(en)
|
2012-02-17 |
2013-08-21 |
Academisch Medisch Centrum |
Rho kinase inhiitors for use in the treatment of neuroblastoma
|
WO2013167475A1
(en)
*
|
2012-05-08 |
2013-11-14 |
Syddansk Universitet |
Anabolic compounds for treating and preventing bone loss diseases
|
US9150570B2
(en)
|
2012-05-31 |
2015-10-06 |
Plexxikon Inc. |
Synthesis of heterocyclic compounds
|
DK3381943T3
(da)
|
2012-07-25 |
2022-05-16 |
Celldex Therapeutics Inc |
Anti-kit-antistoffer og anvendelser deraf
|
CA2887129A1
(en)
|
2012-10-09 |
2014-04-17 |
Igenica, Inc. |
Anti-c16orf54 antibodies and methods of use thereof
|
EP2968469A4
(en)
|
2013-03-15 |
2016-08-31 |
Longevity Biotech Inc |
PEPTIDES COMPRISING NON-ENDOGENIC AMINO ACIDS AND METHODS OF MAKING AND USING SAME
|
EP2990040B1
(en)
|
2013-04-24 |
2019-12-04 |
Kyushu University, National University Corporation |
Therapeutic agent for eyeground disease
|
WO2014177699A1
(en)
*
|
2013-05-03 |
2014-11-06 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Rhoa (rock) inhibitors for the treatment of enflammatory bowel disease
|
WO2014197849A2
(en)
|
2013-06-06 |
2014-12-11 |
Igenica Biotherapeutics, Inc. |
Anti-c10orf54 antibodies and uses thereof
|
EP3906945A3
(en)
|
2013-08-26 |
2022-03-16 |
BioNTech Research and Development, Inc. |
Nucleic acids encoding human antibodies to sialyl-lewis a
|
KR102460549B1
(ko)
|
2014-03-04 |
2022-10-28 |
페이트 세러퓨틱스, 인코포레이티드 |
개선된 재프로그래밍 방법 및 세포 배양 플랫폼
|
GB201403775D0
(en)
|
2014-03-04 |
2014-04-16 |
Kymab Ltd |
Antibodies, uses & methods
|
KR102614642B1
(ko)
|
2014-06-04 |
2023-12-19 |
바이오엔테크 리서치 앤드 디벨롭먼트 인코포레이티드 |
강글리오사이드 gd2에 대한 사람 단클론 항체
|
US20170233698A1
(en)
|
2014-06-27 |
2017-08-17 |
The Regents Of The University Of California |
Cultured mammalian limbal stem cells, methods for generating the same, and uses thereof
|
EP3229838B1
(en)
|
2014-12-11 |
2020-09-09 |
Pierre Fabre Medicament |
Anti-c10orf54 antibodies and uses thereof
|
US10149856B2
(en)
|
2015-01-26 |
2018-12-11 |
BioAxone BioSciences, Inc. |
Treatment of cerebral cavernous malformations and cerebral aneurysms with rho kinase inhibitors
|
US10857157B2
(en)
|
2015-01-26 |
2020-12-08 |
BioAxone BioSciences, Inc. |
Treatment of cerebral cavernous malformations and cerebral aneurysms with rho kinase inhibitors
|
US10106525B2
(en)
|
2015-01-26 |
2018-10-23 |
BioAxone BioSciences, Inc. |
Rho kinase inhibitor BA-1049 (R) and active metabolites thereof
|
CN107847584B
(zh)
|
2015-02-09 |
2022-01-25 |
纪念斯隆凯特琳癌症中心 |
具有人a33抗原和dota金属复合物亲和力的多特异性抗体及其用途
|
CN114504651A
(zh)
|
2015-03-03 |
2022-05-17 |
科马布有限公司 |
抗体、用途和方法
|
PT3313449T
(pt)
|
2015-06-24 |
2020-10-30 |
Nitto Denko Corp |
Compostos ionizáveis e composições e suas utilizações
|
WO2017064119A1
(en)
|
2015-10-13 |
2017-04-20 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods and pharmaceutical compositions for the treatment of retinal capillary non-perfusion
|
EP4088719A1
(en)
|
2015-10-13 |
2022-11-16 |
Institut National de la Santé et de la Recherche Médicale (INSERM) |
Methods and pharmaceutical compositions for the treatment of retinal capillary non-perfusion
|
SG10202111851YA
(en)
|
2015-10-16 |
2021-12-30 |
Fate Therapeutics Inc |
Platform for the Induction & Maintenance of Ground State Pluripotency
|
US10875920B2
(en)
|
2015-12-02 |
2020-12-29 |
Stcube & Co., Inc. |
Antibodies and molecules that immunospecifically bind to BTN1A1 and the therapeutic uses thereof
|
WO2017096017A1
(en)
|
2015-12-02 |
2017-06-08 |
Stsciences, Inc. |
Antibodies specific to glycosylated btla (b- and t- lymphocyte attenuator)
|
WO2018083248A1
(en)
|
2016-11-03 |
2018-05-11 |
Kymab Limited |
Antibodies, combinations comprising antibodies, biomarkers, uses & methods
|
US11198680B2
(en)
|
2016-12-21 |
2021-12-14 |
BioAxone BioSciences, Inc. |
Rho kinase inhibitor BA-1049 (R) and active metabolites thereof
|
CA3065300A1
(en)
|
2017-05-31 |
2018-12-06 |
Stcube & Co., Inc. |
Methods of treating cancer using antibodies and molecules that immunospecifically bind to btn1a1
|
KR20200015602A
(ko)
|
2017-05-31 |
2020-02-12 |
주식회사 에스티큐브앤컴퍼니 |
Btn1a1에 면역특이적으로 결합하는 항체 및 분자 및 이의 치료적 용도
|
CN110997724A
(zh)
|
2017-06-06 |
2020-04-10 |
斯特库伯株式会社 |
使用结合btn1a1或btn1a1-配体的抗体和分子治疗癌症的方法
|
US10537567B2
(en)
|
2017-07-11 |
2020-01-21 |
BioAxone BioSciences, Inc. |
Kinase inhibitors for treatment of disease
|
US11707522B2
(en)
|
2017-10-13 |
2023-07-25 |
Boehringer Ingelheim International Gmbh |
Human antibodies to Tn antigen
|
CN111479568A
(zh)
|
2017-12-21 |
2020-07-31 |
参天制药株式会社 |
司培前列素与Rho激酶抑制剂的组合药物
|
MA53160A
(fr)
|
2018-07-20 |
2021-05-26 |
Pf Medicament |
Récepteur pour vista
|
CA3110661A1
(en)
|
2018-08-29 |
2020-03-05 |
University Of Massachusetts |
Inhibition of protein kinases to treat friedreich ataxia
|
UY38427A
(es)
|
2018-10-26 |
2020-05-29 |
Novartis Ag |
Métodos y composiciones para terapia con células oculares
|
CN111116555B
(zh)
*
|
2018-10-30 |
2023-06-02 |
北京盈科瑞创新药物研究有限公司 |
一种Rho激酶抑制剂及其制备方法和应用
|
WO2020193802A1
(en)
|
2019-03-28 |
2020-10-01 |
Fundación De La Comunidad Valenciana Centro De Investigación Príncipe Felipe |
Polymeric conjugates and uses thereof
|
JP2023522784A
(ja)
|
2020-04-27 |
2023-05-31 |
ノバルティス アーゲー |
眼細胞療法のための方法及び組成物
|
CN111707831A
(zh)
*
|
2020-07-16 |
2020-09-25 |
首都医科大学附属北京朝阳医院 |
Rock激酶活性在辅助诊断sle以及评价sle病情中的应用
|
EP4274578A1
(en)
|
2021-01-11 |
2023-11-15 |
Incyte Corporation |
Combination therapy comprising jak pathway inhibitor and rock inhibitor
|
CN113262226B
(zh)
*
|
2021-04-19 |
2023-05-16 |
杭州市第一人民医院 |
利舒地尔在制备细菌感染治疗药物中的应用
|
CA3235384A1
(en)
|
2021-10-18 |
2023-04-27 |
Takahiro Ochiya |
Compositions and methods of use thereof for treating liver fibrosis
|
CA3235862A1
(en)
|
2021-10-22 |
2023-04-27 |
Takahiro Ochiya |
Methods for making extracellular vesicles, and compositions and methods of use thereof
|
WO2023122213A1
(en)
|
2021-12-22 |
2023-06-29 |
Byomass Inc. |
Targeting gdf15-gfral pathway cross-reference to related applications
|
WO2023147107A1
(en)
|
2022-01-31 |
2023-08-03 |
Byomass Inc. |
Myeloproliferative conditions
|