ES2113106T3 - Esteres de 14alfa,15alfa-metilen-estradiol con efecto estrogeno administrables por via oral. - Google Patents
Esteres de 14alfa,15alfa-metilen-estradiol con efecto estrogeno administrables por via oral.Info
- Publication number
- ES2113106T3 ES2113106T3 ES94917548T ES94917548T ES2113106T3 ES 2113106 T3 ES2113106 T3 ES 2113106T3 ES 94917548 T ES94917548 T ES 94917548T ES 94917548 T ES94917548 T ES 94917548T ES 2113106 T3 ES2113106 T3 ES 2113106T3
- Authority
- ES
- Spain
- Prior art keywords
- methylene
- effects
- 15alfa
- 14alfa
- estres
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J53/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton has been modified by condensation with a carbocyclic rings or by formation of an additional ring by means of a direct link between two ring carbon atoms, including carboxyclic rings fused to the cyclopenta(a)hydrophenanthrene skeleton are included in this class
- C07J53/002—Carbocyclic rings fused
- C07J53/004—3 membered carbocyclic rings
Abstract
LA PRESENTE INVENCION SE REFIERE A ESTERES 14 AL , 15 AL METILENO - ESTRADIOL, DONDE LOS GRUPOS 17 - HIDROXI Y/O LOS GRUPOS 3 - HIDROXI SE ESTERIFICAN. ESTOS ESTERES SON ADECUADOS PARA SU UTILIZACION, CONJUNTAMENTE CON PRODUCTOS AUXILIARES FARMACEUTICOS, COMO MEDICAMENTO, EN PARTICULAR COMO AGENTES CONTRACEPTIVOS O ANTICLIMATERICOS. EXHIBEN UNA ACCION ESTROGENICA QUE ES COMPARADA DE FORMA PRECISA DEFINIDA CON LA DEL ESTRADIOL ETINILO O ESTROGENOS NATURALES, Y SE ADMINISTRAN CON PREFERENCIA DE FORMA ORAL. NO SOLAMENTE SON REDUCIDOS LOS EFECTOS ASOCIADOS DEL AGENTE CONTRACEPTIVO HABITUAL, SINO TAMBIEN SE MEJORA DE MANERA SIGNIFICANTE LA TERAPIA DE SUSTITUCION DE ESTROGENO.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE4322186A DE4322186A1 (de) | 1993-07-03 | 1993-07-03 | Oral estrogen wirksame Ester des 14alpha, 15alpha-Methylen-estradiols |
Publications (1)
Publication Number | Publication Date |
---|---|
ES2113106T3 true ES2113106T3 (es) | 1998-04-16 |
Family
ID=6491888
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES94917548T Expired - Lifetime ES2113106T3 (es) | 1993-07-03 | 1994-06-15 | Esteres de 14alfa,15alfa-metilen-estradiol con efecto estrogeno administrables por via oral. |
Country Status (8)
Country | Link |
---|---|
EP (1) | EP0707593B1 (es) |
CN (1) | CN1102830A (es) |
AT (1) | ATE161542T1 (es) |
AU (1) | AU6923494A (es) |
DE (3) | DE4322186A1 (es) |
ES (1) | ES2113106T3 (es) |
GR (1) | GR3026094T3 (es) |
WO (1) | WO1995001988A1 (es) |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE19906159A1 (de) * | 1999-02-09 | 2000-08-10 | Schering Ag | 16-Hydroxyestratriene als selektiv wirksame Estrogene |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA745995A (en) * | 1962-08-17 | 1966-11-08 | Paturet Michel | 3 ou 17-hexahydrobenzyloxycarbonates de composes steroides et procede |
DD145919B1 (de) * | 1978-06-28 | 1982-06-30 | Kurt Ponsold | Verfahren zur herstellung von 14,1 -methylenderivaten der oestranreihe |
FR2531089B1 (fr) * | 1982-07-27 | 1986-03-21 | Pharmascience Lab | Nouveaux derives oestraniques destines a des applications pharmacologiques par voie topique, et leur procede de preparation |
DE4239946C2 (de) * | 1992-11-27 | 2001-09-13 | Jenapharm Gmbh | Estranderivate mit einer 14alpha,15alpha-Methylengruppe und Verfahren zu ihrer Herstellung |
-
1993
- 1993-07-03 DE DE4322186A patent/DE4322186A1/de not_active Withdrawn
-
1994
- 1994-06-15 AU AU69234/94A patent/AU6923494A/en not_active Abandoned
- 1994-06-15 AT AT94917548T patent/ATE161542T1/de not_active IP Right Cessation
- 1994-06-15 DE DE4494826T patent/DE4494826D2/de not_active Expired - Lifetime
- 1994-06-15 ES ES94917548T patent/ES2113106T3/es not_active Expired - Lifetime
- 1994-06-15 WO PCT/DE1994/000662 patent/WO1995001988A1/de active IP Right Grant
- 1994-06-15 DE DE59404903T patent/DE59404903D1/de not_active Expired - Lifetime
- 1994-06-15 EP EP94917548A patent/EP0707593B1/de not_active Expired - Lifetime
- 1994-07-02 CN CN94108120A patent/CN1102830A/zh active Pending
-
1998
- 1998-02-11 GR GR980400262T patent/GR3026094T3/el unknown
Also Published As
Publication number | Publication date |
---|---|
GR3026094T3 (en) | 1998-05-29 |
ATE161542T1 (de) | 1998-01-15 |
DE4322186A1 (de) | 1995-01-12 |
DE4494826D2 (de) | 1997-07-24 |
CN1102830A (zh) | 1995-05-24 |
EP0707593A1 (de) | 1996-04-24 |
EP0707593B1 (de) | 1997-12-29 |
DE59404903D1 (de) | 1998-02-05 |
WO1995001988A1 (de) | 1995-01-19 |
AU6923494A (en) | 1995-02-06 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FG2A | Definitive protection |
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