HUP0104413A2 - Ascomycineket tartalmazó helyi készítmények - Google Patents
Ascomycineket tartalmazó helyi készítményekInfo
- Publication number
- HUP0104413A2 HUP0104413A2 HU0104413A HUP0104413A HUP0104413A2 HU P0104413 A2 HUP0104413 A2 HU P0104413A2 HU 0104413 A HU0104413 A HU 0104413A HU P0104413 A HUP0104413 A HU P0104413A HU P0104413 A2 HUP0104413 A2 HU P0104413A2
- Authority
- HU
- Hungary
- Prior art keywords
- ascomycins
- topical compositions
- carrier material
- ascomycin
- epidermis
- Prior art date
Links
- 239000000203 mixture Substances 0.000 title 1
- 230000000699 topical effect Effects 0.000 title 1
- 239000012876 carrier material Substances 0.000 abstract 2
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 2
- ZDQSOHOQTUFQEM-PKUCKEGBSA-N ascomycin Chemical compound C/C([C@H]1OC(=O)[C@@H]2CCCCN2C(=O)C(=O)[C@]2(O)O[C@@H]([C@H](C[C@H]2C)OC)[C@@H](OC)C[C@@H](C)C\C(C)=C/[C@H](C(C[C@H](O)[C@H]1C)=O)CC)=C\[C@@H]1CC[C@@H](O)[C@H](OC)C1 ZDQSOHOQTUFQEM-PKUCKEGBSA-N 0.000 abstract 1
- ZDQSOHOQTUFQEM-XCXYXIJFSA-N ascomycin Natural products CC[C@H]1C=C(C)C[C@@H](C)C[C@@H](OC)[C@H]2O[C@@](O)([C@@H](C)C[C@H]2OC)C(=O)C(=O)N3CCCC[C@@H]3C(=O)O[C@H]([C@H](C)[C@@H](O)CC1=O)C(=C[C@@H]4CC[C@@H](O)[C@H](C4)OC)C ZDQSOHOQTUFQEM-XCXYXIJFSA-N 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 210000002615 epidermis Anatomy 0.000 abstract 1
- 238000001704 evaporation Methods 0.000 abstract 1
- 239000000463 material Substances 0.000 abstract 1
- 238000002360 preparation method Methods 0.000 abstract 1
- 210000003491 skin Anatomy 0.000 abstract 1
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0014—Skin, i.e. galenical aspects of topical compositions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/44—Oils, fats or waxes according to two or more groups of A61K47/02-A61K47/42; Natural or modified natural oils, fats or waxes, e.g. castor oil, polyethoxylated castor oil, montan wax, lignite, shellac, rosin, beeswax or lanolin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
- A61K31/436—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a six-membered ring having oxygen as a ring hetero atom, e.g. rapamycin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/02—Inorganic compounds
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/12—Carboxylic acids; Salts or anhydrides thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/14—Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Epidemiology (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Dermatology (AREA)
- Immunology (AREA)
- Communicable Diseases (AREA)
- Rheumatology (AREA)
- Oncology (AREA)
- Pain & Pain Management (AREA)
- Transplantation (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
A találmány tárgya ascomycin helyi beadására szolgáló készítmény,amely egy hordozóanyagot tartalmaz, amely hordozóanyag a víznek abelső bőrrétegben való megtartására szolgáló anyagból és a víznek abőrből való elpárolgását megakadályozó szerből áll. Ó
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GBGB9826656.2A GB9826656D0 (en) | 1998-12-03 | 1998-12-03 | Organic compounds |
PCT/EP1999/009351 WO2000032234A1 (en) | 1998-12-03 | 1999-12-01 | Topical compositions comprising ascomycins |
Publications (3)
Publication Number | Publication Date |
---|---|
HUP0104413A2 true HUP0104413A2 (hu) | 2002-03-28 |
HUP0104413A3 HUP0104413A3 (en) | 2003-12-29 |
HU228742B1 HU228742B1 (en) | 2013-05-28 |
Family
ID=10843626
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
HU0104413A HU228742B1 (en) | 1998-12-03 | 1999-12-01 | Topical compositions comprising ascomycins |
Country Status (28)
Country | Link |
---|---|
US (3) | US20010051650A1 (hu) |
EP (1) | EP1135163B1 (hu) |
JP (1) | JP3993745B2 (hu) |
KR (1) | KR100514027B1 (hu) |
CN (1) | CN1213767C (hu) |
AT (1) | ATE278422T1 (hu) |
AU (1) | AU767156B2 (hu) |
BR (1) | BR9915861A (hu) |
CA (1) | CA2350884C (hu) |
CZ (1) | CZ301295B6 (hu) |
DE (1) | DE69920949T2 (hu) |
DK (1) | DK1135163T3 (hu) |
ES (1) | ES2230905T3 (hu) |
GB (1) | GB9826656D0 (hu) |
HK (1) | HK1040362A1 (hu) |
HU (1) | HU228742B1 (hu) |
IL (2) | IL143093A0 (hu) |
NO (1) | NO330576B1 (hu) |
NZ (1) | NZ511687A (hu) |
PL (1) | PL196628B1 (hu) |
PT (1) | PT1135163E (hu) |
RU (1) | RU2234319C2 (hu) |
SI (1) | SI1135163T1 (hu) |
SK (1) | SK285811B6 (hu) |
TR (1) | TR200101547T2 (hu) |
TW (1) | TWI245640B (hu) |
WO (1) | WO2000032234A1 (hu) |
ZA (1) | ZA200104529B (hu) |
Families Citing this family (16)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20070032853A1 (en) | 2002-03-27 | 2007-02-08 | Hossainy Syed F | 40-O-(2-hydroxy)ethyl-rapamycin coated stent |
US20030050692A1 (en) * | 2000-12-22 | 2003-03-13 | Avantec Vascular Corporation | Delivery of therapeutic capable agents |
AUPR529701A0 (en) * | 2001-05-28 | 2001-06-21 | Fujisawa Pharmaceutical Co., Ltd. | Pharmaceutical composition |
GB0123400D0 (en) | 2001-09-28 | 2001-11-21 | Novartis Ag | Organic compounds |
US7442391B2 (en) * | 2002-01-25 | 2008-10-28 | Integrated Botanical Technologies, Llc | Bioactive botanical cosmetic compositions and processes for their production |
PE20030828A1 (es) * | 2002-03-04 | 2003-11-04 | Novartis Ag | Composicion oftalmica que comprende ascomicina |
GB0218996D0 (en) * | 2002-08-14 | 2002-09-25 | Novartis Ag | Organic compounds |
EP1594484A2 (en) * | 2003-02-17 | 2005-11-16 | Cipla Ltd. | Pharmaceutical patch |
GB0307866D0 (en) * | 2003-04-04 | 2003-05-14 | Novartis Ag | Pharmaceutical composition |
US20050118344A1 (en) | 2003-12-01 | 2005-06-02 | Pacetti Stephen D. | Temperature controlled crimping |
GB0408070D0 (en) * | 2004-04-08 | 2004-05-12 | Novartis Ag | Pharmaceutical formulations |
ES2389443T3 (es) * | 2004-04-08 | 2012-10-26 | Meda Pharma S.À.R.L. | Composición de espuma de pimecrolimus que contiene hexilenglicol, opcionalmente alcohol de oleílo, dimetilisosorbida y/o triglicéridos de cadena media |
US7758901B2 (en) * | 2007-02-16 | 2010-07-20 | Betty Bellman | Compositions and methods for alleviating skin disorders |
DE102008006791B4 (de) * | 2008-01-30 | 2011-11-24 | Lts Lohmann Therapie-Systeme Ag | Transdermales Therapeutisches System mit Harnstoff-Komponente und Verfahren zu dessen Herstellung |
KR101201956B1 (ko) | 2009-03-18 | 2012-11-19 | 신동헌 | 파카스트리사민을 유효성분으로 함유하는 과증식성 피부질환과 악성흑색종의 예방 또는 치료용 약학적 조성물 |
JP7090549B2 (ja) * | 2016-03-02 | 2022-06-24 | ノヴァン,インコーポレイテッド | 炎症のための治療用組成物およびその治療方法 |
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JPH08143458A (ja) | 1994-11-17 | 1996-06-04 | Sekisui Chem Co Ltd | 経皮吸収貼付剤 |
JPH08231369A (ja) | 1995-02-20 | 1996-09-10 | Shiseido Co Ltd | 化粧料 |
AR004480A1 (es) * | 1995-04-06 | 1998-12-16 | Amico Derin C D | Compuestos de ascomicina que poseen actividad antiinflamatoria, pro cedimiento para prepararlos, uso de dichos compuestos para preparar agentesfarmaceuticos y composiciones farmaceuticas que los incluyen |
HUP9801745A3 (en) | 1995-05-31 | 2000-04-28 | Schering Ag | Sorbic-acid-containing hydrogels |
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DE19549243A1 (de) | 1995-12-21 | 1997-06-26 | Schering Ag | Pharmazeutische Präparate enthaltend Clathrate von Cyclodextrinen und nichtnatürliche Vitamin D-Analoga |
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JPH09315954A (ja) | 1996-05-30 | 1997-12-09 | Kita:Kk | 眼科手術後の眼組織混濁防止剤。 |
EP0929227A1 (en) * | 1996-09-05 | 1999-07-21 | The Pillsbury Company | Savory cheese fillings and food products including these fillings |
JPH10231248A (ja) | 1997-02-19 | 1998-09-02 | T T S Gijutsu Kenkyusho:Kk | ジヒドロエトルフィン含有経皮吸収型製剤 |
JPH10251137A (ja) | 1997-03-14 | 1998-09-22 | Advanced Sukin Res Kenkyusho:Kk | 光線過敏症抑制剤 |
GB9713730D0 (en) | 1997-06-30 | 1997-09-03 | Ciba Geigy Ag | Organic compounds |
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GB9723669D0 (en) | 1997-11-07 | 1998-01-07 | Univ Aberdeen | Skin penetration enhancing components |
US6113892A (en) * | 1997-12-23 | 2000-09-05 | Helene Curtis, Inc. | Compositions for cleansing, conditioning and moisturizing hair and skin |
US5981464A (en) * | 1998-01-26 | 1999-11-09 | Lever Brothers Company, Division Of Conopco, Inc. | Adjuvant composition |
EP0937453A3 (en) * | 1998-01-26 | 2000-04-19 | Sam Schwartz | Cosmetic and tissue cleansing and moisturizing composition |
ATE363275T1 (de) | 1998-04-27 | 2007-06-15 | Astellas Pharma Inc | Pharmazeutische gelformulierung enthaltend eine trizyklische substanz (fk-506/tacrolimus) |
GB9814640D0 (en) | 1998-07-06 | 1998-09-02 | Fujisawa Pharmaceutical Co | New use |
US6124362A (en) * | 1998-07-17 | 2000-09-26 | The Procter & Gamble Company | Method for regulating hair growth |
-
1998
- 1998-12-03 GB GBGB9826656.2A patent/GB9826656D0/en not_active Ceased
-
1999
- 1999-12-01 EP EP99959372A patent/EP1135163B1/en not_active Expired - Lifetime
- 1999-12-01 NZ NZ511687A patent/NZ511687A/en not_active IP Right Cessation
- 1999-12-01 HU HU0104413A patent/HU228742B1/hu unknown
- 1999-12-01 CZ CZ20011908A patent/CZ301295B6/cs not_active IP Right Cessation
- 1999-12-01 WO PCT/EP1999/009351 patent/WO2000032234A1/en active IP Right Grant
- 1999-12-01 AT AT99959372T patent/ATE278422T1/de active
- 1999-12-01 SK SK762-2001A patent/SK285811B6/sk not_active IP Right Cessation
- 1999-12-01 DE DE69920949T patent/DE69920949T2/de not_active Expired - Lifetime
- 1999-12-01 BR BR9915861-2A patent/BR9915861A/pt not_active Application Discontinuation
- 1999-12-01 IL IL14309399A patent/IL143093A0/xx active IP Right Grant
- 1999-12-01 DK DK99959372T patent/DK1135163T3/da active
- 1999-12-01 PT PT99959372T patent/PT1135163E/pt unknown
- 1999-12-01 TR TR2001/01547T patent/TR200101547T2/xx unknown
- 1999-12-01 RU RU2001118049/15A patent/RU2234319C2/ru active
- 1999-12-01 CN CNB998140139A patent/CN1213767C/zh not_active Expired - Lifetime
- 1999-12-01 PL PL348750A patent/PL196628B1/pl unknown
- 1999-12-01 CA CA002350884A patent/CA2350884C/en not_active Expired - Lifetime
- 1999-12-01 AU AU16569/00A patent/AU767156B2/en not_active Expired
- 1999-12-01 ES ES99959372T patent/ES2230905T3/es not_active Expired - Lifetime
- 1999-12-01 JP JP2000584923A patent/JP3993745B2/ja not_active Expired - Lifetime
- 1999-12-01 SI SI9930704T patent/SI1135163T1/xx unknown
- 1999-12-01 KR KR10-2001-7006906A patent/KR100514027B1/ko active IP Right Grant
-
2000
- 2000-05-15 TW TW089109254A patent/TWI245640B/zh not_active IP Right Cessation
-
2001
- 2001-05-10 IL IL143093A patent/IL143093A/en not_active IP Right Cessation
- 2001-05-29 NO NO20012624A patent/NO330576B1/no not_active IP Right Cessation
- 2001-05-31 US US09/871,367 patent/US20010051650A1/en not_active Abandoned
- 2001-06-01 ZA ZA200104529A patent/ZA200104529B/xx unknown
- 2001-12-31 HK HK01109240A patent/HK1040362A1/xx unknown
-
2005
- 2005-11-03 US US11/266,639 patent/US20060058279A1/en not_active Abandoned
-
2011
- 2011-08-05 US US13/204,489 patent/US9402802B2/en not_active Expired - Fee Related
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