PE20030828A1 - Composicion oftalmica que comprende ascomicina - Google Patents

Composicion oftalmica que comprende ascomicina

Info

Publication number
PE20030828A1
PE20030828A1 PE2003000198A PE2003000198A PE20030828A1 PE 20030828 A1 PE20030828 A1 PE 20030828A1 PE 2003000198 A PE2003000198 A PE 2003000198A PE 2003000198 A PE2003000198 A PE 2003000198A PE 20030828 A1 PE20030828 A1 PE 20030828A1
Authority
PE
Peru
Prior art keywords
ascomycin
acid
composition including
ophthalmic composition
chloride
Prior art date
Application number
PE2003000198A
Other languages
English (en)
Inventor
Shau-Fong Yen
Maggy Babiole Saunier
Michelle Pik-Han Wong
Jean-Claude Bizec
Original Assignee
Novartis Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=27791682&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=PE20030828(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Novartis Ag filed Critical Novartis Ag
Publication of PE20030828A1 publication Critical patent/PE20030828A1/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0048—Eye, e.g. artificial tears
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/436—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a six-membered ring having oxygen as a ring hetero atom, e.g. rapamycin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/14—Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/14—Decongestants or antiallergics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Ophthalmology & Optometry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pain & Pain Management (AREA)
  • Communicable Diseases (AREA)
  • Rheumatology (AREA)
  • Oncology (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)

Abstract

QUE TIENE APLICACION EN EL TRATAMIENTO DE ENFERMEDADES INFLAMATORIAS, TALES COMO BLEFARITIS, QUE COMPRENDE: A)UNA ASCOMICINA QUE ES 33-EPI-CLORO-33-DESOXI-ASCOMICINA; B)UN VEHICULO, QUE COMPRENDE: i)UN TRIGLICERIDO DE CADENA MEDIANA; Y/O ii)MIRISTATO DE ISOPROPILO; iii)UNA BASE DE UNGUENTO; Y, iv)AGUA Y UN EMULSIONANTE TAL COMO ACIDO ALQUILCARBOXILICO DE 16 A 18 ATOMOS DE CARBONO ETOXILADO O ESTEARATO DE PEGOXOL (TEFOSE 63); Y, C)UN CONSERVADOR, SELECCIONADO DE: a)UN AMONIO CUATERNARIO TAL COMO CLORURO DE BENZALCONIO, CLORURO DE BEZOXONIO, BROMURO DE DOMIFENO (BRADOSOL) Y SIMILARES; b)SALES ALQUILMERCURICAS DEL ACIDO TIOSALICILICO, TALES COMO: TIOMERSAL, NITRATO FENILMERCURICO O BORATO FENILMERCURICO; c)PARABENOS; d)DERIVADOS DE BIGUANIDA; e)COMPLEJOS DE OXICLORO ESTABILIZADOS, BAJO EL NOMBRE COMERCIAL PURITE; ENTRE OTROS Y UNA MEZCLA DE LOS MISMOS
PE2003000198A 2002-03-04 2003-02-28 Composicion oftalmica que comprende ascomicina PE20030828A1 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US36151502P 2002-03-04 2002-03-04
US40927502P 2002-09-09 2002-09-09

Publications (1)

Publication Number Publication Date
PE20030828A1 true PE20030828A1 (es) 2003-11-04

Family

ID=27791682

Family Applications (1)

Application Number Title Priority Date Filing Date
PE2003000198A PE20030828A1 (es) 2002-03-04 2003-02-28 Composicion oftalmica que comprende ascomicina

Country Status (28)

Country Link
US (4) US20050220823A1 (es)
EP (1) EP1482936B1 (es)
JP (1) JP4740542B2 (es)
KR (1) KR100992948B1 (es)
CN (1) CN1297270C (es)
AR (1) AR038628A1 (es)
AT (1) ATE341326T1 (es)
AU (1) AU2003218679B2 (es)
BR (1) BR0308184A (es)
CA (1) CA2477769C (es)
CO (1) CO5611133A2 (es)
DE (1) DE60308836T2 (es)
DK (1) DK1482936T3 (es)
EC (1) ECSP045277A (es)
EG (1) EG24403A (es)
ES (1) ES2274214T3 (es)
HK (1) HK1071301A1 (es)
IL (2) IL163657A0 (es)
MX (1) MXPA04008571A (es)
MY (1) MY137563A (es)
NO (1) NO20044092L (es)
NZ (1) NZ534690A (es)
PE (1) PE20030828A1 (es)
PL (1) PL210870B1 (es)
PT (1) PT1482936E (es)
RU (1) RU2322982C2 (es)
TW (1) TW200305437A (es)
WO (1) WO2003074054A1 (es)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP4463681B2 (ja) 2002-07-15 2010-05-19 アルコン，インコーポレイテッド 眼内使用のための非ポリマー親油性薬学的インプラント組成物
WO2004009056A1 (en) * 2002-07-23 2004-01-29 Novartis Ag Ophtalmic ointment composition comprising a drug, an ointment base and a solubiling/dispersing agent
GB0307866D0 (en) * 2003-04-04 2003-05-14 Novartis Ag Pharmaceutical composition
BRPI0705564B8 (pt) * 2007-10-10 2021-05-25 Embrapa Pesquisa Agropecuaria sistema do tipo cristal líquido contínuo contendo co-solvente portador de substâncias fracamente solúveis em água, seu processo de obtenção e seus usos
EP2238878A1 (en) 2009-04-09 2010-10-13 Nestec S.A. Beverage preparation device having a closing mechanism with force demultiplying means
US8728516B2 (en) * 2009-04-30 2014-05-20 Abbvie Inc. Stabilized lipid formulation of apoptosis promoter
CN102458382B (zh) * 2009-05-12 2015-03-18 咖勒尼卡公司 莫米松和丙二醇的水包油乳状液
CA2780177A1 (en) * 2009-12-22 2011-06-30 Abbott Laboratories Abt-263 capsule
JP2013523828A (ja) * 2010-04-07 2013-06-17 アラーガン インコーポレイテッド 眼科用組成物のための保存剤の組み合わせ
RU2531937C2 (ru) * 2012-05-14 2014-10-27 Открытое Акционерное Общество "Татхимфармпрепараты" Состав и способ получения глазной мази
EP2664329A1 (de) * 2012-05-15 2013-11-20 F. Holzer GmbH Ophthalmologisches Vehikelsystem
US20160074321A1 (en) * 2013-03-27 2016-03-17 Comprehensive Drug Enterprises, Ltd. Ophthalmic composition, method for preparing the same, and use of the same
US11103464B2 (en) * 2013-11-29 2021-08-31 Rohto Pharmaceutical Co., Ltd. Aqueous composition for ophthalmological use or otolaryngological use
US20200237859A1 (en) 2019-01-25 2020-07-30 Newport Research, Inc. Aqueous suspensions of cyclosporin
US11324800B2 (en) 2015-01-15 2022-05-10 Wellspring Ophthalmics, Inc. Aqueous suspensions of cyclosporin
US10606760B2 (en) * 2017-08-23 2020-03-31 Samsung Electronics Co., Ltd. Nonvolatile memory devices and methods of controlling the same
EP3741367A1 (en) 2019-05-21 2020-11-25 Premark Pharma GmbH Treatment of ocular disease

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK0406791T3 (da) * 1989-07-05 1995-03-27 Fujisawa Pharmaceutical Co Vandigt flydende præparat til ekstern anvendelse
ATE150304T1 (de) * 1990-09-04 1997-04-15 Fujisawa Pharmaceutical Co Tricyclische verbindungen enthaltende salben
PH31204A (en) * 1990-11-02 1998-05-05 Fujisawa Pharmaceutical Co Pharmaceutical composition.
CA2054983A1 (en) * 1990-11-08 1992-05-09 Sotoo Asakura Suspendible composition and process for preparing the same
EP0656779B1 (en) * 1992-08-28 2000-04-12 Pharmos Corporation Submicron emulsions as ocular drug delivery vehicles
JPH06345646A (ja) * 1993-06-08 1994-12-20 Fujisawa Pharmaceut Co Ltd ローション剤
EP0664705B1 (en) * 1993-08-18 2000-10-04 Alcon Laboratories, Inc. Compositions of ergoline derivatives for the treatment of glaucoma
EP0785780A1 (en) * 1994-10-10 1997-07-30 Novartis AG Ophthalmic and aural compositions containing diclofenac potassium
EP0786986B1 (en) * 1994-10-26 2002-03-20 Novartis AG Use of an unsaturated fatty alcohol
FR2732598B1 (fr) * 1995-04-10 1997-05-09 Oreal Utilisation de sel de metaux alcalino-terreux pour le traitement des prurits et des dysesthesies oculaires ou palpebraux
FR2755852B1 (fr) * 1996-11-15 1998-12-24 Oreal Utilisation d'un alkylether de glycerol dans une composition cosmetique et/ou dermatologique comme actif pour le traitement de la seborrhee et de l'acne
KR100406823B1 (ko) * 1998-04-27 2003-11-21 후지사와 야꾸힝 고교 가부시키가이샤 의약 조성물
GB9826656D0 (en) * 1998-12-03 1999-01-27 Novartis Ag Organic compounds
CZ20013769A3 (cs) * 1999-04-30 2002-03-13 Sucampo Ag Činidlo pro léčbu suchého oka

Also Published As

Publication number Publication date
RU2322982C2 (ru) 2008-04-27
ATE341326T1 (de) 2006-10-15
PL370917A1 (en) 2005-06-13
EG24403A (en) 2009-04-29
BR0308184A (pt) 2005-01-11
CN1638769A (zh) 2005-07-13
AU2003218679B2 (en) 2007-04-05
RU2004129593A (ru) 2005-09-10
AR038628A1 (es) 2005-01-19
JP4740542B2 (ja) 2011-08-03
US20120015971A1 (en) 2012-01-19
KR20040094718A (ko) 2004-11-10
PT1482936E (pt) 2007-01-31
ES2274214T3 (es) 2007-05-16
IL163657A0 (en) 2005-12-18
MY137563A (en) 2009-02-27
CN1297270C (zh) 2007-01-31
NZ534690A (en) 2007-06-29
CO5611133A2 (es) 2006-02-28
US20100113501A1 (en) 2010-05-06
NO20044092L (no) 2004-09-27
US20050220823A1 (en) 2005-10-06
DK1482936T3 (da) 2007-01-08
DE60308836T2 (de) 2007-04-26
HK1071301A1 (en) 2005-07-15
CA2477769A1 (en) 2003-09-12
ECSP045277A (es) 2004-10-26
KR100992948B1 (ko) 2010-11-08
EP1482936A1 (en) 2004-12-08
CA2477769C (en) 2011-01-18
JP2005529851A (ja) 2005-10-06
DE60308836D1 (de) 2006-11-16
EP1482936B1 (en) 2006-10-04
TW200305437A (en) 2003-11-01
IL163657A (en) 2009-11-18
WO2003074054A1 (en) 2003-09-12
US20110152307A1 (en) 2011-06-23
PL210870B1 (pl) 2012-03-30
MXPA04008571A (es) 2004-12-06
AU2003218679A1 (en) 2003-09-16

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