HUT66531A - Heteroatoms-containing tricyclic compounds, pharmaceutical prepns contg. them and process for producing them - Google Patents

Heteroatoms-containing tricyclic compounds, pharmaceutical prepns contg. them and process for producing them

Info

Publication number
HUT66531A
HUT66531A HU9301190A HU9301190A HUT66531A HU T66531 A HUT66531 A HU T66531A HU 9301190 A HU9301190 A HU 9301190A HU 9301190 A HU9301190 A HU 9301190A HU T66531 A HUT66531 A HU T66531A
Authority
HU
Hungary
Prior art keywords
contg
heteroatoms
producing
tricyclic compounds
containing tricyclic
Prior art date
Application number
HU9301190A
Other languages
Hungarian (hu)
Other versions
HU9301190D0 (en
Inventor
Karl Baumann
Original Assignee
Sandoz Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB929209815A external-priority patent/GB9209815D0/en
Priority claimed from GB939304927A external-priority patent/GB9304927D0/en
Application filed by Sandoz Ag filed Critical Sandoz Ag
Publication of HU9301190D0 publication Critical patent/HU9301190D0/en
Publication of HUT66531A publication Critical patent/HUT66531A/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/12—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains three hetero rings
    • C07D491/18—Bridged systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/01—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing oxygen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/16—Central respiratory analeptics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/10—Anti-acne agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/14—Drugs for dermatological disorders for baldness or alopecia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/10—Antioedematous agents; Diuretics

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Dermatology (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Pulmonology (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Transplantation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Saccharide Compounds (AREA)

Abstract

The invention concerns the compounds of formulae <CHEM> wherein the substituents have various significances. They can be prepared by various methods, e.g. acylation, reduction, alkylation, etc. They are indicated for use as pharmaceuticals, in particular as immunosuppressant, antiproliferative and antiinflammatory agents.
HU9301190A 1992-05-07 1993-04-22 Heteroatoms-containing tricyclic compounds, pharmaceutical prepns contg. them and process for producing them HUT66531A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB929209815A GB9209815D0 (en) 1992-05-07 1992-05-07 Organic compounds,processes for their production and their use
GB939304927A GB9304927D0 (en) 1993-03-10 1993-03-10 Organic compounds

Publications (2)

Publication Number Publication Date
HU9301190D0 HU9301190D0 (en) 1993-07-28
HUT66531A true HUT66531A (en) 1994-12-28

Family

ID=26300836

Family Applications (2)

Application Number Title Priority Date Filing Date
HU9301190A HUT66531A (en) 1992-05-07 1993-04-22 Heteroatoms-containing tricyclic compounds, pharmaceutical prepns contg. them and process for producing them
HU95P/P00246P HU211135A9 (en) 1992-05-07 1995-06-19 Heteroatoms-containing tricyclic compounds

Family Applications After (1)

Application Number Title Priority Date Filing Date
HU95P/P00246P HU211135A9 (en) 1992-05-07 1995-06-19 Heteroatoms-containing tricyclic compounds

Country Status (25)

Country Link
US (1) US5514685A (en)
EP (1) EP0569337B1 (en)
JP (1) JP2788392B2 (en)
KR (1) KR100292311B1 (en)
CN (1) CN1037773C (en)
AT (1) ATE155787T1 (en)
AU (1) AU668152B2 (en)
CA (1) CA2095659C (en)
CY (1) CY2126B1 (en)
CZ (1) CZ291773B6 (en)
DE (1) DE69312386T2 (en)
DK (1) DK0569337T3 (en)
ES (1) ES2105193T3 (en)
FI (2) FI102612B (en)
GR (1) GR3024754T3 (en)
HU (2) HUT66531A (en)
IL (1) IL105607A (en)
MY (1) MY109602A (en)
NO (1) NO305865B1 (en)
NZ (1) NZ247553A (en)
PH (1) PH30456A (en)
RU (1) RU2126009C1 (en)
SG (1) SG47011A1 (en)
SK (1) SK282061B6 (en)
TW (1) TW330936B (en)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MY110603A (en) * 1993-05-27 1998-08-29 Novartis Ag Tetrahydropyran derivatives
GB9421613D0 (en) * 1994-10-26 1994-12-14 Sandoz Ltd Organic compounds
IL115742A (en) 1994-10-26 2000-06-01 Novartis Ag Pharmaceutical compositions comprising a difficultly soluble active agent a hydrophilic phase a lipophilic phase and a surfactant
ATE214593T1 (en) 1994-10-26 2002-04-15 Novartis Erfind Verwalt Gmbh USE OF AN UNSATURATED FAT ALCOHOL
KR100440553B1 (en) 1998-03-26 2004-07-15 후지사와 야꾸힝 고교 가부시키가이샤 Sustained release preparations
CA2326222C (en) * 1998-04-27 2008-09-23 Fujisawa Pharmaceutical Co., Ltd. Medicinal compositions
GB9826656D0 (en) 1998-12-03 1999-01-27 Novartis Ag Organic compounds
US7063857B1 (en) 1999-04-30 2006-06-20 Sucampo Ag Use of macrolide compounds for the treatment of dry eye
GB0008785D0 (en) 2000-04-10 2000-05-31 Novartis Ag Organic compounds
RU2206298C2 (en) * 2000-09-22 2003-06-20 Государственное учреждение Межотраслевой научно-технический комплекс "Микрохирургия глаза" Method for treating the cases of glaucoma
CA2492989C (en) 2002-07-23 2012-11-20 Novartis Ag Ophthalmic ointment composition comprising a drug, an ointment base and a solubilizing/dispersing agent
KR100469917B1 (en) * 2002-09-09 2005-02-02 (주)조은식품 A Pumpkin added pumpkin seed and Method of Preparing thereof
KR100745493B1 (en) * 2005-12-16 2007-08-03 주식회사농심 Injection snacks with improved texture and manufacturing method thereof
EP2552923B1 (en) * 2010-04-02 2014-03-26 Janssen R&D Ireland Macrocyclic integrase inhibitors
JPWO2016068208A1 (en) 2014-10-28 2017-08-10 晃史 山口 Drugs for improving pregnancy status and use thereof
EP3834826A4 (en) 2018-08-10 2022-07-27 Koushi Yamaguchi Therapeutic agent for humoral immunity-related diseases in materno-fetal relationship
US20220062245A1 (en) 2018-12-18 2022-03-03 Koushi Yamaguchi Agent for improving infertility, recurrent miscarriage, and state of pregnancy

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3842069A (en) * 1973-06-21 1974-10-15 Abbott Lab 4"-deoxy-4"-oxoerythromycin b derivatives
US4952605A (en) * 1983-08-03 1990-08-28 The Regents Of The University Of California Manoalide analogs
US4894366A (en) * 1984-12-03 1990-01-16 Fujisawa Pharmaceutical Company, Ltd. Tricyclo compounds, a process for their production and a pharmaceutical composition containing the same
US5254562A (en) * 1984-12-03 1993-10-19 Fujisawa Pharmaceutical Company, Ltd. Tricyclo compounds, a process for their production and a pharmaceutical composition containing the same
DE68904037T2 (en) * 1988-10-12 1993-06-03 Merck & Co Inc METHOD FOR TRANSFERRING FK-506 WITH THE PARTICIPATION OF HYDROXIDE.
CA1316916C (en) * 1988-10-12 1993-04-27 David Askin Hydroxide mediated fk-506 rearrangement product
JPH07108101B2 (en) * 1989-02-28 1995-11-15 オ−クマ株式会社 Linear actuator drive controller
KR920700212A (en) * 1989-06-14 1992-02-19 쟝 크라머·한스 루돌프 하우스 Heteroatom-Containing Tricyclic Compounds
EP0413532A3 (en) * 1989-08-18 1991-05-15 Fisons Plc Macrocyclic compounds
IE904050A1 (en) * 1989-11-13 1991-05-22 Merck & Co Inc Aminomacrolides and derivatives having immunosuppressive¹activity
US5260301A (en) * 1990-03-01 1993-11-09 Fujisawa Pharmaceutical Co., Ltd. Pharmaceutical solution containing FK-506
GB2246350A (en) * 1990-07-23 1992-01-29 Fujisawa Pharmaceutical Co Tricyclo compounds
US5384316A (en) * 1990-08-18 1995-01-24 Fisons Plc 4,16-diazatetracyclo[23.3.1.1.Hu 14,17=b . 0 Hu 4,9 triaconta-16,19-diene-2,3,10-trione derivatives
EP0480623A1 (en) * 1990-10-11 1992-04-15 Merck & Co. Inc. New halomacrolides and derivatives having immunosuppressive activity
WO1992013862A1 (en) * 1991-02-05 1992-08-20 Fujisawa Pharmaceutical Co., Ltd. Lactone compounds
WO1993004680A1 (en) * 1991-09-05 1993-03-18 Abbott Laboratories Macrocyclic immunomodulators

Also Published As

Publication number Publication date
MY109602A (en) 1997-03-31
CN1083486A (en) 1994-03-09
TW330936B (en) 1998-05-01
SG47011A1 (en) 1998-03-20
NO931627L (en) 1993-11-08
FI932035A7 (en) 1993-11-08
JP2788392B2 (en) 1998-08-20
FI102612B1 (en) 1999-01-15
AU3839393A (en) 1993-11-11
SK282061B6 (en) 2001-10-08
KR100292311B1 (en) 2001-09-17
DE69312386T2 (en) 1998-01-29
IL105607A (en) 1998-01-04
ATE155787T1 (en) 1997-08-15
DK0569337T3 (en) 1998-01-19
GR3024754T3 (en) 1997-12-31
PH30456A (en) 1997-05-28
IL105607A0 (en) 1993-09-22
NO305865B1 (en) 1999-08-09
FI982476A0 (en) 1998-11-16
ES2105193T3 (en) 1997-10-16
SK43593A3 (en) 1995-07-11
NZ247553A (en) 1995-07-26
JPH0641144A (en) 1994-02-15
RU2126009C1 (en) 1999-02-10
EP0569337B1 (en) 1997-07-23
HU9301190D0 (en) 1993-07-28
CZ82993A3 (en) 1994-01-19
KR940005631A (en) 1994-03-22
CZ291773B6 (en) 2003-05-14
FI102612B (en) 1999-01-15
CN1037773C (en) 1998-03-18
EP0569337A1 (en) 1993-11-10
NO931627D0 (en) 1993-05-05
FI932035A0 (en) 1993-05-05
FI982476A7 (en) 1998-11-16
HU211135A9 (en) 1995-10-30
CY2126B1 (en) 2002-06-21
CA2095659C (en) 2005-08-09
US5514685A (en) 1996-05-07
CA2095659A1 (en) 1993-11-08
DE69312386D1 (en) 1997-08-28
AU668152B2 (en) 1996-04-26

Similar Documents

Publication Publication Date Title
HUT66531A (en) Heteroatoms-containing tricyclic compounds, pharmaceutical prepns contg. them and process for producing them
SG47520A1 (en) New method for the production of 9-amino-6-demethyl-6-deoxytetracycline
TW269678B (en)
PL300062A1 (en) Novel 7-(substituted)-8-(substituted)-9-[(substituted glycil) amido]-6-demethyl-6-deoxytetracyclines, methods of obtaining such compounds as well as their organic and inorganic salts and metal complex, pharmaceutical agent and veterinary agent
EG20279A (en) New derivatives of 3 arylpyrazoles used as fungicides
HU9401582D0 (en) Maqcrolide tetrahydropyrane derivatives
GB9121943D0 (en) Organic compounds,processes for their production and their use
EP0551844A3 (en)
ATE158293T1 (en) POLYCYCLIC 31668P AND 31668U COMPOUNDS, METHOD FOR THE PRODUCTION THEREOF AND THEIR USE AS ANTIBIOTIC OR ANTITUMORAL DRUGS
HU913278D0 (en) Pirimidine derivatives, fungicides containinmg them, and process for the production of the compounds
EP0412941A3 (en) Phospholipids for the treatment of multiple sclerosis
GB9220601D0 (en) New organic compounds,processes for production thereof and their use
GB9204579D0 (en) Organic compounds,processes for their production and their use
GB9204609D0 (en) Organic compounds,processes for their production and their use
GB9209815D0 (en) Organic compounds,processes for their production and their use

Legal Events

Date Code Title Description
DGB9 Succession in title of applicant

Owner name: NOVARTIS AG., CH

DFC4 Cancellation of temporary protection due to refusal