HU199473B - Process for producing chrystalline carbapenem derivative and pharmaceutical compositions comprising same as active ingredient - Google Patents

Process for producing chrystalline carbapenem derivative and pharmaceutical compositions comprising same as active ingredient Download PDF

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Publication number
HU199473B
HU199473B HU873521A HU352187A HU199473B HU 199473 B HU199473 B HU 199473B HU 873521 A HU873521 A HU 873521A HU 352187 A HU352187 A HU 352187A HU 199473 B HU199473 B HU 199473B
Authority
HU
Hungary
Prior art keywords
compound
group
crystalline
formula
priority
Prior art date
Application number
HU873521A
Other languages
English (en)
Hungarian (hu)
Other versions
HUT44553A (en
Inventor
Makoto Sunagawa
Yuzuru Isobe
Yutaka Takeuchi
Tetsuo Noguchi
Yukio Ozaki
Haruki Matsumura
Original Assignee
Sumitomo Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sumitomo Pharma filed Critical Sumitomo Pharma
Publication of HUT44553A publication Critical patent/HUT44553A/hu
Publication of HU199473B publication Critical patent/HU199473B/hu

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D477/00—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring
    • C07D477/10—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2
    • C07D477/12—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, attached in position 6
    • C07D477/16—Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, attached in position 6 with hetero atoms or carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 3
    • C07D477/20—Sulfur atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
HU873521A 1986-07-30 1987-07-30 Process for producing chrystalline carbapenem derivative and pharmaceutical compositions comprising same as active ingredient HU199473B (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP17932186 1986-07-30
JP15776987 1987-06-26

Publications (2)

Publication Number Publication Date
HUT44553A HUT44553A (en) 1988-03-28
HU199473B true HU199473B (en) 1990-02-28

Family

ID=26485103

Family Applications (1)

Application Number Title Priority Date Filing Date
HU873521A HU199473B (en) 1986-07-30 1987-07-30 Process for producing chrystalline carbapenem derivative and pharmaceutical compositions comprising same as active ingredient

Country Status (20)

Country Link
US (1) US4888344A (enExample)
EP (1) EP0256377B1 (enExample)
JP (1) JP2665767B2 (enExample)
AR (1) AR243189A1 (enExample)
AU (1) AU596857B2 (enExample)
CA (1) CA1322371C (enExample)
DE (1) DE3781980T2 (enExample)
DK (1) DK172666B1 (enExample)
ES (1) ES2052524T3 (enExample)
FI (1) FI88037C (enExample)
GR (1) GR3006254T3 (enExample)
HK (1) HK169595A (enExample)
HU (1) HU199473B (enExample)
IE (1) IE60588B1 (enExample)
IL (1) IL83372A (enExample)
LU (1) LU88635I2 (enExample)
MX (1) MX173359B (enExample)
NO (2) NO165543C (enExample)
NZ (1) NZ221224A (enExample)
PH (1) PH24710A (enExample)

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CN102532140B (zh) * 2010-12-21 2015-03-11 北大方正集团有限公司 一种美罗培南三水合物的制备方法
CN102250096B (zh) * 2011-09-05 2016-04-06 江西华邦药业有限公司 一种美罗培南的制备方法
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CN103570718B (zh) * 2012-07-31 2016-06-29 深圳市海滨制药有限公司 一种美罗培南原料药、其制备方法及包含其的药物组合物
CN103570719B (zh) * 2012-07-31 2016-03-02 深圳市海滨制药有限公司 一种美罗培南原料药、其制备方法及包含其的药物组合物
KR101331762B1 (ko) * 2012-12-28 2013-11-20 주식회사 대웅제약 메로페넴의 삼수화물의 제조방법
CN103044429B (zh) * 2013-01-28 2015-04-01 苏州二叶制药有限公司 一种美罗培南的制备方法
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KR102144777B1 (ko) 2013-06-19 2020-08-18 제이더블유중외제약 주식회사 결정형 메로페넴 삼수화물의 제조방법
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Also Published As

Publication number Publication date
GR3006254T3 (enExample) 1993-06-21
EP0256377A1 (en) 1988-02-24
NO873205D0 (no) 1987-07-30
AU7619687A (en) 1988-03-03
ES2052524T3 (es) 1994-07-16
AU596857B2 (en) 1990-05-17
FI873299A0 (fi) 1987-07-29
JP2665767B2 (ja) 1997-10-22
NO1997013I1 (no) 1997-10-17
IE60588B1 (en) 1994-07-27
FI88037C (fi) 1993-03-25
MX7534A (es) 1993-10-01
DK399087D0 (da) 1987-07-30
IL83372A0 (en) 1987-12-31
MX173359B (es) 1994-02-23
NZ221224A (en) 1989-10-27
CA1322371C (en) 1993-09-21
US4888344A (en) 1989-12-19
PH24710A (en) 1990-10-01
IL83372A (en) 1992-05-25
NO165543C (no) 1991-02-27
FI88037B (fi) 1992-12-15
EP0256377B1 (en) 1992-09-30
NO165543B (no) 1990-11-19
LU88635I2 (fr) 1995-12-01
DE3781980T2 (de) 1993-02-18
NO873205L (no) 1988-02-01
HUT44553A (en) 1988-03-28
AR243189A1 (es) 1993-07-30
HK169595A (en) 1995-11-10
FI873299L (fi) 1988-01-31
DE3781980D1 (de) 1992-11-05
IE871959L (en) 1988-01-30
DK172666B1 (da) 1999-05-10
DK399087A (da) 1988-01-31
JPS6434986A (en) 1989-02-06

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Legal Events

Date Code Title Description
HU90 Patent valid on 900628
GB9A Succession in title

Owner name: DAINIPPON SUMITOMO PHARMA CO., LTD., JP

Free format text: FORMER OWNER(S): SUMITOMO PHARMACEUTICALS CO. LTD., JP