HRP20000340B1 - Derivati benzodioksana, benzofurana ili benzopirana koji imaju svojstva relaksacije fundusa - Google Patents

Derivati benzodioksana, benzofurana ili benzopirana koji imaju svojstva relaksacije fundusa

Info

Publication number
HRP20000340B1
HRP20000340B1 HR20000340A HRP20000340A HRP20000340B1 HR P20000340 B1 HRP20000340 B1 HR P20000340B1 HR 20000340 A HR20000340 A HR 20000340A HR P20000340 A HRP20000340 A HR P20000340A HR P20000340 B1 HRP20000340 B1 HR P20000340B1
Authority
HR
Croatia
Prior art keywords
alkyl
formula
alkyloxy
hydrogen
divalent radical
Prior art date
Application number
HR20000340A
Other languages
English (en)
Croatian (hr)
Inventor
Tom Bert Paul Wigerinck Piet
Gaston Verschueren Wim
Francis Josephine Schroven Marc
Frans Leopold De Bruyn Marcel
Original Assignee
Janssen Pharmaceutica N.V.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Janssen Pharmaceutica N.V. filed Critical Janssen Pharmaceutica N.V.
Publication of HRP20000340A2 publication Critical patent/HRP20000340A2/hr
Publication of HRP20000340B1 publication Critical patent/HRP20000340B1/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nutrition Science (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
HR20000340A 1997-12-05 1998-11-27 Derivati benzodioksana, benzofurana ili benzopirana koji imaju svojstva relaksacije fundusa HRP20000340B1 (hr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP97203808 1997-12-05
PCT/EP1998/007771 WO1999029687A1 (en) 1997-12-05 1998-11-27 (benzodioxan, benzofuran or benzopyran) derivatives having fundic relaxation properties

Publications (2)

Publication Number Publication Date
HRP20000340A2 HRP20000340A2 (en) 2001-04-30
HRP20000340B1 true HRP20000340B1 (hr) 2008-12-31

Family

ID=8229014

Family Applications (1)

Application Number Title Priority Date Filing Date
HR20000340A HRP20000340B1 (hr) 1997-12-05 1998-11-27 Derivati benzodioksana, benzofurana ili benzopirana koji imaju svojstva relaksacije fundusa

Country Status (31)

Country Link
US (4) US6133277A (cs)
EP (1) EP1036073B8 (cs)
JP (1) JP2001525407A (cs)
KR (1) KR100591605B1 (cs)
CN (1) CN1155597C (cs)
AR (1) AR017195A1 (cs)
AT (1) ATE334125T1 (cs)
AU (1) AU748669B2 (cs)
BG (1) BG64624B1 (cs)
BR (1) BR9814256A (cs)
CA (1) CA2311669C (cs)
CO (1) CO5011114A1 (cs)
CZ (1) CZ297895B6 (cs)
DE (1) DE69835372T2 (cs)
EA (1) EA003365B1 (cs)
EE (1) EE04438B1 (cs)
ES (1) ES2270541T3 (cs)
HR (1) HRP20000340B1 (cs)
HU (1) HU224813B1 (cs)
ID (1) ID24616A (cs)
IL (1) IL136529A (cs)
MY (1) MY124586A (cs)
NO (1) NO320727B1 (cs)
NZ (1) NZ503603A (cs)
PL (1) PL191144B1 (cs)
SK (1) SK286268B6 (cs)
TR (1) TR200001542T2 (cs)
TW (1) TW577886B (cs)
UA (1) UA70308C2 (cs)
WO (1) WO1999029687A1 (cs)
ZA (1) ZA9811081B (cs)

Families Citing this family (37)

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US6133277A (en) 1997-12-05 2000-10-17 Janssen Pharmaceutica N.V. (Benzodioxan, benzofuran or benzopyran) derivatives having fundic relaxation properties
BR0011247A (pt) * 1999-06-02 2002-03-05 Janssen Pharmaceutica Nv Derivados (benzodioxano, benzofurano ou benzopirano) de pirrolidinila, piperidinila ou homopiperidinila substituìdos
WO2000075136A1 (en) * 1999-06-02 2000-12-14 Janssen Pharmaceutica N.V. Aminoalkyl substituted (benzodioxan, benzofuran or benzopyran) derivatives
JO2352B1 (en) * 2000-06-22 2006-12-12 جانسين فارماسيوتيكا ان. في Compounds for the treatment of non-adaptation of the bottom of the uterus
JO2654B1 (en) * 2000-09-04 2012-06-17 شركة جانسين فارماسوتيكا ان. في Multiple aryl caroxa amides are useful as lipid - lowering agents
JO2409B1 (en) 2000-11-21 2007-06-17 شركة جانسين فارماسوتيكا ان. في Second-phenyl carboxy amides are useful as lipid-lowering agents
US6688079B2 (en) 2001-04-18 2004-02-10 Kraft Foods Holdings, Inc. Method for manufacturing flexible packages having slide closures
EP1445324A4 (en) * 2001-11-09 2005-02-16 Kaneka Corp PROCESS FOR PRODUCING OPTICALLY ACTIVE CHROMAN DERIVATIVE AND INTERMEDIATE PRODUCT
ES2199086B1 (es) 2002-07-31 2005-06-01 Cepa Schwarz Pharma Sl Nuevos derivados de cicloalcanodionas, procedimiento para su preparacion y sus aplicaciones farmacologicas.
US7071821B2 (en) * 2003-05-14 2006-07-04 Bellsouth Intellectual Property Corporation Method and system for alerting a person to a situation
ITTO20030140U1 (it) * 2003-09-16 2005-03-17 Interfila Srl Matita cosmetica
US7514461B2 (en) * 2003-09-19 2009-04-07 Edison Pharmaceuticals, Inc. Chroman derivatives
BRPI0416817A (pt) 2003-11-20 2007-03-06 Janssen Pharmaceutica Nv 2-quinolinonas e 2-quinoxalinonas 7-fenilalquila substituìdas como inibidores da poli(adp-ribose)polimerase
KR101118582B1 (ko) 2003-11-20 2012-02-27 얀센 파마슈티카 엔.브이. 폴리(ａｄｐ-리보스)폴리머라제 저해제로서의 6-알케닐 및6-페닐알킬 치환된 2-퀴놀리논 및 2-퀴녹살리논
ES2238015B1 (es) * 2004-01-30 2006-11-01 Cepa Schwarz Pharma, S.L. Derivados de cicloalcanodionas con actividad neuroprotectora.
CA2568835C (en) 2004-06-30 2014-05-27 Janssen Pharmaceutica N.V. Quinazolinone derivatives as parp inhibitors
US7803795B2 (en) 2004-06-30 2010-09-28 Janssen Pharmaceutica N.V. Phthalazine derivatives as parp inhibitors
NZ551801A (en) * 2004-06-30 2009-11-27 Janssen Pharmaceutica Nv Quinazolinedione derivatives as PARP inhibitors
DE102004032277A1 (de) * 2004-07-02 2006-01-19 Basell Polyolefine Gmbh Verfahren zur racemoselektiven Synthese von ansa-Metallocenen
JP2008504331A (ja) * 2004-07-02 2008-02-14 バーゼル、ポリオレフィン、ゲゼルシャフト、ミット、ベシュレンクテル、ハフツング アンサ−メタロセンをラセモ選択的に合成する方法
BRPI0608353A2 (pt) 2005-02-17 2009-12-01 Wyeth Corp derivados de indol, benzotiofeno, benzofurano e indeno cicloalquilfundidos
PE20061297A1 (es) * 2005-04-22 2006-12-24 Wyeth Corp Compuestos derivados de cromano y cromeno moduladores del receptor de serotonina 5-ht2c
WO2008015538A2 (en) * 2006-07-31 2008-02-07 Schwarz Pharma S.L. Use of diaza- and thiaza-cycloalkanediones for preventing and/or treating pain and /or migraine
US20080033050A1 (en) * 2006-08-04 2008-02-07 Richards Patricia Allison Tewe Method of treating thermoregulatory disfunction with paroxetine
US8503431B2 (en) * 2006-08-25 2013-08-06 Wireless Wonders Ltd. Mobile phone related indirect communication system and method
SI2134691T1 (sl) 2007-03-08 2012-06-29 Janssen Pharmaceutica Nv Derivati kvinolina kot PARP in TANK inhibitorji
JP5017703B2 (ja) * 2007-05-16 2012-09-05 住友ゴム工業株式会社 ビードエイペックスおよびタイヤ
JP5525447B2 (ja) 2007-10-26 2014-06-18 ジヤンセン・フアーマシユーチカ・ナームローゼ・フエンノートシヤツプ Ｐａｒｐ阻害剤としてのキノリノン誘導体
ATE513818T1 (de) 2008-03-27 2011-07-15 Janssen Pharmaceutica Nv Chinazolinonderivate als tubulinpolymerisationshemmer
WO2009118382A1 (en) 2008-03-27 2009-10-01 Janssen Pharmaceutica Nv Tetrahydrophenanthridinones and tetrahydrocyclopentaquinolinones as parp and tubulin polymerization inhibitors
CA2864332C (en) 2012-02-24 2020-08-25 Lupin Limited Substituted chroman compounds as calcium sensing receptor modulators
DE102012206062B4 (de) 2012-04-13 2019-09-12 Adidas Ag Schuhoberteil
WO2014102592A2 (en) 2012-12-27 2014-07-03 Purdue Pharma L.P. Oxime/substituted quinoxaline-type piperidine compounds and uses thereof
DE102013207163B4 (de) 2013-04-19 2022-09-22 Adidas Ag Schuhoberteil
DE102014220087B4 (de) 2014-10-02 2016-05-12 Adidas Ag Flachgestricktes Schuhoberteil für Sportschuhe
CN108713021A (zh) 2015-12-30 2018-10-26 耶路撒冷希伯来大学伊森姆研究发展有限公司 Pt(IV)前药
CN119462701A (zh) * 2024-10-11 2025-02-18 合肥工业大学 一种四吡啶草酸铜金属配合物的制备及用途

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US3910930A (en) * 1973-01-04 1975-10-07 Janssen Pharmaceutica Nv 1-{55 1-{8 2-(1,4-Benzodioxan-2-yl)-2-hydroxyethyl{9 -4-piperidyl{56 -2-benzimidazolinones
US3929801A (en) * 1973-11-20 1975-12-30 Janssen Pharmaceutica Nv 2-Benzimidazolinones
GB1599296A (en) * 1977-07-06 1981-09-30 Brewster D L Ice making machine
GR71865B (cs) * 1978-03-20 1983-07-07 Ciba Geigy
DE2852945A1 (de) * 1978-12-07 1980-06-26 Boehringer Sohn Ingelheim Benzodioxanyl-hydroxyaethylpiperidyl- imidazolidinone, verfahren zu ihrer herstellung und diese enthaltende arzneimittel
US4329348A (en) * 1979-02-26 1982-05-11 Ciba-Geigy Corporation N-Oxacyclic-alkylpiperidines as psychostimulants
US4239348A (en) * 1979-11-30 1980-12-16 Hughes Aircraft Company High resolution AC silicon MOS light-valve substrate
DE3901814A1 (de) * 1988-07-28 1990-02-01 Bayer Ag Substituierte aminomethylzetraline sowie ihre heterocyclischen analoga
DE4140540A1 (de) * 1991-12-09 1993-06-17 Bayer Ag Neue azaheterocyclylmethyl-chromane
SI9300097B (en) * 1992-02-27 2001-12-31 Janssen Pharmaceutica Nv (benzodioxan, benzofuran or benzopyran) alkylamino) alkyl substituted guanidines
DE4319038A1 (de) * 1993-06-08 1994-12-15 Bayer Ag Verwendung von teilweise bekannten substituierten Chromanen als Arzneimittel, neue Wirkstoffe und Verfahren zu ihrer Herstellung
AU677428B2 (en) * 1993-08-19 1997-04-24 Janssen Pharmaceutica N.V. Vasoconstrictive dihydrobenzopyran derivatives
US5541199A (en) * 1995-06-02 1996-07-30 American Home Products Corporation Chroman-2-ylmethylamino derivatives
FR2744451B1 (fr) * 1996-02-01 1998-04-24 Pf Medicament Nouvelles imidazolidinones, pyrimidinones, et 1,3-diazepin-2 -ones, leur preparation et leurs applications en therapeutique
US5696653A (en) * 1996-12-13 1997-12-09 Phase Metrics Tooling for holding a head gimbal assembly
US6133277A (en) 1997-12-05 2000-10-17 Janssen Pharmaceutica N.V. (Benzodioxan, benzofuran or benzopyran) derivatives having fundic relaxation properties

Also Published As

Publication number Publication date
EE04438B1 (et) 2005-02-15
ES2270541T3 (es) 2007-04-01
EA003365B1 (ru) 2003-04-24
HU224813B1 (en) 2006-02-28
BG64624B1 (bg) 2005-09-30
NO20002074D0 (no) 2000-04-19
AU2412799A (en) 1999-06-28
PL341007A1 (en) 2001-03-12
US6495547B1 (en) 2002-12-17
CA2311669A1 (en) 1999-06-17
SK8032000A3 (en) 2001-02-12
AU748669B2 (en) 2002-06-06
NO320727B1 (no) 2006-01-23
KR20010031010A (ko) 2001-04-16
TR200001542T2 (tr) 2001-01-22
US6852714B2 (en) 2005-02-08
JP2001525407A (ja) 2001-12-11
TW577886B (en) 2004-03-01
CZ20002018A3 (cs) 2000-10-11
EP1036073A1 (en) 2000-09-20
HK1028400A1 (en) 2001-02-16
ATE334125T1 (de) 2006-08-15
KR100591605B1 (ko) 2006-06-20
CN1155597C (zh) 2004-06-30
HUP0004492A3 (en) 2002-04-29
ZA9811081B (en) 2000-06-22
IL136529A (en) 2003-03-12
HUP0004492A2 (hu) 2002-03-28
BG104372A (en) 2000-12-29
CN1280577A (zh) 2001-01-17
CZ297895B6 (cs) 2007-04-25
DE69835372T2 (de) 2007-08-09
IL136529A0 (en) 2001-06-14
US20030149093A1 (en) 2003-08-07
US6133277A (en) 2000-10-17
US6747045B2 (en) 2004-06-08
CO5011114A1 (es) 2001-02-28
NZ503603A (en) 2001-10-26
SK286268B6 (sk) 2008-06-06
EP1036073B8 (en) 2006-11-15
BR9814256A (pt) 2000-10-03
WO1999029687A8 (en) 2000-04-13
DE69835372D1 (de) 2006-09-07
AR017195A1 (es) 2001-08-22
CA2311669C (en) 2010-04-27
HRP20000340A2 (en) 2001-04-30
EP1036073B1 (en) 2006-07-26
UA70308C2 (uk) 2004-10-15
NO20002074L (no) 2000-06-02
US20030083365A1 (en) 2003-05-01
PL191144B1 (pl) 2006-03-31
EE200000328A (et) 2001-08-15
EA200000616A1 (ru) 2000-12-25
WO1999029687A1 (en) 1999-06-17
MY124586A (en) 2006-06-30
ID24616A (id) 2000-07-27

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