IL136529A - Benzodioxan, benzofuran or benzopyran derivatives having fundic relaxation properties, their preparation and pharmaceutical compositions containing them - Google Patents
Benzodioxan, benzofuran or benzopyran derivatives having fundic relaxation properties, their preparation and pharmaceutical compositions containing themInfo
- Publication number
- IL136529A IL136529A IL13652998A IL13652998A IL136529A IL 136529 A IL136529 A IL 136529A IL 13652998 A IL13652998 A IL 13652998A IL 13652998 A IL13652998 A IL 13652998A IL 136529 A IL136529 A IL 136529A
- Authority
- IL
- Israel
- Prior art keywords
- benzodioxan
- benzofuran
- preparation
- pharmaceutical compositions
- compositions containing
- Prior art date
Links
- IANQTJSKSUMEQM-UHFFFAOYSA-N 1-benzofuran Chemical compound C1=CC=C2OC=CC2=C1 IANQTJSKSUMEQM-UHFFFAOYSA-N 0.000 title 2
- BNBQRQQYDMDJAH-UHFFFAOYSA-N benzodioxan Chemical compound C1=CC=C2OCCOC2=C1 BNBQRQQYDMDJAH-UHFFFAOYSA-N 0.000 title 1
- 150000001562 benzopyrans Chemical class 0.000 title 1
- 239000008194 pharmaceutical composition Substances 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Nutrition Science (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP97203808 | 1997-12-05 | ||
| PCT/EP1998/007771 WO1999029687A1 (en) | 1997-12-05 | 1998-11-27 | (benzodioxan, benzofuran or benzopyran) derivatives having fundic relaxation properties |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IL136529A0 IL136529A0 (en) | 2001-06-14 |
| IL136529A true IL136529A (en) | 2003-03-12 |
Family
ID=8229014
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IL13652998A IL136529A (en) | 1997-12-05 | 1998-11-27 | Benzodioxan, benzofuran or benzopyran derivatives having fundic relaxation properties, their preparation and pharmaceutical compositions containing them |
Country Status (31)
| Country | Link |
|---|---|
| US (4) | US6133277A (cs) |
| EP (1) | EP1036073B8 (cs) |
| JP (1) | JP2001525407A (cs) |
| KR (1) | KR100591605B1 (cs) |
| CN (1) | CN1155597C (cs) |
| AR (1) | AR017195A1 (cs) |
| AT (1) | ATE334125T1 (cs) |
| AU (1) | AU748669B2 (cs) |
| BG (1) | BG64624B1 (cs) |
| BR (1) | BR9814256A (cs) |
| CA (1) | CA2311669C (cs) |
| CO (1) | CO5011114A1 (cs) |
| CZ (1) | CZ297895B6 (cs) |
| DE (1) | DE69835372T2 (cs) |
| EA (1) | EA003365B1 (cs) |
| EE (1) | EE04438B1 (cs) |
| ES (1) | ES2270541T3 (cs) |
| HR (1) | HRP20000340B1 (cs) |
| HU (1) | HU224813B1 (cs) |
| ID (1) | ID24616A (cs) |
| IL (1) | IL136529A (cs) |
| MY (1) | MY124586A (cs) |
| NO (1) | NO320727B1 (cs) |
| NZ (1) | NZ503603A (cs) |
| PL (1) | PL191144B1 (cs) |
| SK (1) | SK286268B6 (cs) |
| TR (1) | TR200001542T2 (cs) |
| TW (1) | TW577886B (cs) |
| UA (1) | UA70308C2 (cs) |
| WO (1) | WO1999029687A1 (cs) |
| ZA (1) | ZA9811081B (cs) |
Families Citing this family (36)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6133277A (en) | 1997-12-05 | 2000-10-17 | Janssen Pharmaceutica N.V. | (Benzodioxan, benzofuran or benzopyran) derivatives having fundic relaxation properties |
| EP1187829B1 (en) * | 1999-06-02 | 2003-12-10 | Janssen Pharmaceutica N.V. | Aminoalkyl substituted (benzodioxan, benzofuran or benzopyran) derivatives |
| CN1131862C (zh) * | 1999-06-02 | 2003-12-24 | 詹森药业有限公司 | 经吡咯烷基、哌啶基或高哌啶基取代的(苯并二噁烷,苯并呋喃或苯并吡喃)衍生物 |
| JO2352B1 (en) * | 2000-06-22 | 2006-12-12 | جانسين فارماسيوتيكا ان. في | Compounds for the treatment of non-adaptation of the bottom of the uterus |
| JO2654B1 (en) * | 2000-09-04 | 2012-06-17 | شركة جانسين فارماسوتيكا ان. في | Multiple aryl caroxa amides are useful as lipid - lowering agents |
| JO2409B1 (en) * | 2000-11-21 | 2007-06-17 | شركة جانسين فارماسوتيكا ان. في | Second-phenyl carboxy amides are useful as lipid-lowering agents |
| US6688079B2 (en) | 2001-04-18 | 2004-02-10 | Kraft Foods Holdings, Inc. | Method for manufacturing flexible packages having slide closures |
| EP1445324A4 (en) * | 2001-11-09 | 2005-02-16 | Kaneka Corp | PROCESS FOR PRODUCING OPTICALLY ACTIVE CHROMAN DERIVATIVE AND INTERMEDIATE PRODUCT |
| ES2199086B1 (es) | 2002-07-31 | 2005-06-01 | Cepa Schwarz Pharma Sl | Nuevos derivados de cicloalcanodionas, procedimiento para su preparacion y sus aplicaciones farmacologicas. |
| US7071821B2 (en) * | 2003-05-14 | 2006-07-04 | Bellsouth Intellectual Property Corporation | Method and system for alerting a person to a situation |
| ITTO20030140U1 (it) * | 2003-09-16 | 2005-03-17 | Interfila Srl | Matita cosmetica |
| US7514461B2 (en) * | 2003-09-19 | 2009-04-07 | Edison Pharmaceuticals, Inc. | Chroman derivatives |
| WO2005054209A1 (en) | 2003-11-20 | 2005-06-16 | Janssen Pharmaceutica N.V. | 7-phenylalkyl substituted 2-quinolinones and 2 quinoxalinones as poly(adp-ribose) polymerase inhibitors |
| US7855207B2 (en) | 2003-11-20 | 2010-12-21 | Janssen Pharmaceutica, Nv | 6-alkenyl and 6-phenylalkyl substituted 2-quinolinones and 2-quinoxalinones as poly(adpribose) polymerase inhibitors |
| ES2238015B1 (es) * | 2004-01-30 | 2006-11-01 | Cepa Schwarz Pharma, S.L. | Derivados de cicloalcanodionas con actividad neuroprotectora. |
| SG154432A1 (en) | 2004-06-30 | 2009-08-28 | Janssen Pharmaceutica Nv | Quinazolinedione derivatives as parp inhibitors |
| CA2569826C (en) | 2004-06-30 | 2013-07-16 | Janssen Pharmaceutica N.V. | Substituted 2-alkyl quinazolinone derivatives as parp inhibitors |
| JP4852540B2 (ja) | 2004-06-30 | 2012-01-11 | ジヤンセン・フアーマシユーチカ・ナームローゼ・フエンノートシヤツプ | Parp阻害剤としてのフタラジン誘導体 |
| DE102004032277A1 (de) * | 2004-07-02 | 2006-01-19 | Basell Polyolefine Gmbh | Verfahren zur racemoselektiven Synthese von ansa-Metallocenen |
| RU2391350C2 (ru) * | 2004-07-02 | 2010-06-10 | Базелль Полиолефине Гмбх | Способ рацемоселективного синтеза анса-металлоценов |
| WO2006089053A2 (en) | 2005-02-17 | 2006-08-24 | Wyeth | Cycloalkylfused indole, benzothiophene, benzofuran and indene derivatives |
| WO2006116165A1 (en) * | 2005-04-22 | 2006-11-02 | Wyeth | Chromane and chromene derivatives and uses thereof |
| WO2008015538A2 (en) * | 2006-07-31 | 2008-02-07 | Schwarz Pharma S.L. | Use of diaza- and thiaza-cycloalkanediones for preventing and/or treating pain and /or migraine |
| US20080033050A1 (en) | 2006-08-04 | 2008-02-07 | Richards Patricia Allison Tewe | Method of treating thermoregulatory disfunction with paroxetine |
| US8503431B2 (en) * | 2006-08-25 | 2013-08-06 | Wireless Wonders Ltd. | Mobile phone related indirect communication system and method |
| SI2134691T1 (sl) | 2007-03-08 | 2012-06-29 | Janssen Pharmaceutica Nv | Derivati kvinolina kot PARP in TANK inhibitorji |
| JP5017703B2 (ja) * | 2007-05-16 | 2012-09-05 | 住友ゴム工業株式会社 | ビードエイペックスおよびタイヤ |
| WO2009053373A1 (en) | 2007-10-26 | 2009-04-30 | Janssen Pharmaceutica Nv | Quinolinone derivatives as parp inhibitors |
| RU2490260C2 (ru) | 2008-03-27 | 2013-08-20 | Янссен Фармацевтика Нв | Тетрагидрофенантридиноны и тетрагидроциклопентахинолиноны в качестве ингибиторов parp и ингибиторов полимеризации тубулина |
| AU2009228945B2 (en) | 2008-03-27 | 2013-05-02 | Janssen Pharmaceutica Nv | Quinazolinone derivatives as tubulin polymerization inhibitors |
| SG11201405117SA (en) | 2012-02-24 | 2014-09-26 | Lupin Ltd | Substituted chroman compounds as calcium sensing receptor modulators |
| DE102012206062B4 (de) | 2012-04-13 | 2019-09-12 | Adidas Ag | Schuhoberteil |
| WO2014102592A2 (en) | 2012-12-27 | 2014-07-03 | Purdue Pharma L.P. | Oxime/substituted quinoxaline-type piperidine compounds and uses thereof |
| DE102013207163B4 (de) | 2013-04-19 | 2022-09-22 | Adidas Ag | Schuhoberteil |
| DE102014220087B4 (de) | 2014-10-02 | 2016-05-12 | Adidas Ag | Flachgestricktes Schuhoberteil für Sportschuhe |
| EP3397643A1 (en) | 2015-12-30 | 2018-11-07 | Yissum Research Development Company of the Hebrew University of Jerusalem Ltd. | Pt(IV) PRODRUGS |
Family Cites Families (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3910930A (en) * | 1973-01-04 | 1975-10-07 | Janssen Pharmaceutica Nv | 1-{55 1-{8 2-(1,4-Benzodioxan-2-yl)-2-hydroxyethyl{9 -4-piperidyl{56 -2-benzimidazolinones |
| US3929801A (en) * | 1973-11-20 | 1975-12-30 | Janssen Pharmaceutica Nv | 2-Benzimidazolinones |
| GB1599296A (en) * | 1977-07-06 | 1981-09-30 | Brewster D L | Ice making machine |
| GR71865B (cs) * | 1978-03-20 | 1983-07-07 | Ciba Geigy | |
| DE2852945A1 (de) * | 1978-12-07 | 1980-06-26 | Boehringer Sohn Ingelheim | Benzodioxanyl-hydroxyaethylpiperidyl- imidazolidinone, verfahren zu ihrer herstellung und diese enthaltende arzneimittel |
| US4329348A (en) * | 1979-02-26 | 1982-05-11 | Ciba-Geigy Corporation | N-Oxacyclic-alkylpiperidines as psychostimulants |
| US4239348A (en) * | 1979-11-30 | 1980-12-16 | Hughes Aircraft Company | High resolution AC silicon MOS light-valve substrate |
| DE3901814A1 (de) * | 1988-07-28 | 1990-02-01 | Bayer Ag | Substituierte aminomethylzetraline sowie ihre heterocyclischen analoga |
| DE4140540A1 (de) * | 1991-12-09 | 1993-06-17 | Bayer Ag | Neue azaheterocyclylmethyl-chromane |
| SI9300097B (en) * | 1992-02-27 | 2001-12-31 | Janssen Pharmaceutica Nv | (benzodioxan, benzofuran or benzopyran) alkylamino) alkyl substituted guanidines |
| DE4319038A1 (de) * | 1993-06-08 | 1994-12-15 | Bayer Ag | Verwendung von teilweise bekannten substituierten Chromanen als Arzneimittel, neue Wirkstoffe und Verfahren zu ihrer Herstellung |
| HU226525B1 (en) * | 1993-08-19 | 2009-03-30 | Janssen Pharmaceutica Nv | Vasocontrictive dihydrobenzopyran derivatives, pharmaceutical compositions containing them and process for preparing them |
| US5541199A (en) * | 1995-06-02 | 1996-07-30 | American Home Products Corporation | Chroman-2-ylmethylamino derivatives |
| FR2744451B1 (fr) * | 1996-02-01 | 1998-04-24 | Pf Medicament | Nouvelles imidazolidinones, pyrimidinones, et 1,3-diazepin-2 -ones, leur preparation et leurs applications en therapeutique |
| US5696653A (en) * | 1996-12-13 | 1997-12-09 | Phase Metrics | Tooling for holding a head gimbal assembly |
| US6133277A (en) * | 1997-12-05 | 2000-10-17 | Janssen Pharmaceutica N.V. | (Benzodioxan, benzofuran or benzopyran) derivatives having fundic relaxation properties |
-
1998
- 1998-11-16 US US09/192,686 patent/US6133277A/en not_active Expired - Lifetime
- 1998-11-25 TW TW087119526A patent/TW577886B/zh not_active IP Right Cessation
- 1998-11-27 KR KR1020007003796A patent/KR100591605B1/ko not_active Expired - Fee Related
- 1998-11-27 CZ CZ20002018A patent/CZ297895B6/cs not_active IP Right Cessation
- 1998-11-27 NZ NZ503603A patent/NZ503603A/en unknown
- 1998-11-27 DE DE69835372T patent/DE69835372T2/de not_active Expired - Lifetime
- 1998-11-27 SK SK803-2000A patent/SK286268B6/sk not_active IP Right Cessation
- 1998-11-27 TR TR2000/01542T patent/TR200001542T2/xx unknown
- 1998-11-27 BR BR9814256-9A patent/BR9814256A/pt not_active Application Discontinuation
- 1998-11-27 EP EP98966603A patent/EP1036073B8/en not_active Expired - Lifetime
- 1998-11-27 EA EA200000616A patent/EA003365B1/ru not_active IP Right Cessation
- 1998-11-27 AT AT98966603T patent/ATE334125T1/de not_active IP Right Cessation
- 1998-11-27 CN CNB988118319A patent/CN1155597C/zh not_active Expired - Fee Related
- 1998-11-27 ID IDW20001041D patent/ID24616A/id unknown
- 1998-11-27 WO PCT/EP1998/007771 patent/WO1999029687A1/en active IP Right Grant
- 1998-11-27 PL PL341007A patent/PL191144B1/pl not_active IP Right Cessation
- 1998-11-27 EE EEP200000328A patent/EE04438B1/xx not_active IP Right Cessation
- 1998-11-27 ES ES98966603T patent/ES2270541T3/es not_active Expired - Lifetime
- 1998-11-27 IL IL13652998A patent/IL136529A/xx not_active IP Right Cessation
- 1998-11-27 UA UA2000053031A patent/UA70308C2/uk unknown
- 1998-11-27 CA CA2311669A patent/CA2311669C/en not_active Expired - Lifetime
- 1998-11-27 HR HR20000340A patent/HRP20000340B1/xx not_active IP Right Cessation
- 1998-11-27 AU AU24127/99A patent/AU748669B2/en not_active Ceased
- 1998-11-27 HU HU0004492A patent/HU224813B1/hu not_active IP Right Cessation
- 1998-11-27 JP JP2000524281A patent/JP2001525407A/ja active Pending
- 1998-12-01 MY MYPI98005442A patent/MY124586A/en unknown
- 1998-12-01 CO CO98071204A patent/CO5011114A1/es unknown
- 1998-12-03 ZA ZA9811081A patent/ZA9811081B/xx unknown
- 1998-12-04 AR ARP980106182A patent/AR017195A1/es active IP Right Grant
-
2000
- 2000-04-19 NO NO20002074A patent/NO320727B1/no not_active IP Right Cessation
- 2000-04-24 BG BG104372A patent/BG64624B1/bg unknown
- 2000-08-18 US US09/641,485 patent/US6495547B1/en not_active Expired - Lifetime
-
2002
- 2002-04-03 US US10/116,590 patent/US6747045B2/en not_active Expired - Lifetime
- 2002-09-05 US US10/235,623 patent/US6852714B2/en not_active Expired - Lifetime
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FF | Patent granted | ||
| KB | Patent renewed | ||
| KB | Patent renewed | ||
| MM9K | Patent not in force due to non-payment of renewal fees |