ATE334125T1 - (benzodioxan, benzofuran, oder benzopyran) derivate mit fundic entspannungseigenschaften - Google Patents

(benzodioxan, benzofuran, oder benzopyran) derivate mit fundic entspannungseigenschaften

Info

Publication number
ATE334125T1
ATE334125T1 AT98966603T AT98966603T ATE334125T1 AT E334125 T1 ATE334125 T1 AT E334125T1 AT 98966603 T AT98966603 T AT 98966603T AT 98966603 T AT98966603 T AT 98966603T AT E334125 T1 ATE334125 T1 AT E334125T1
Authority
AT
Austria
Prior art keywords
benzopyrane
benzodioxane
benzofuran
derivatives
relaxation properties
Prior art date
Application number
AT98966603T
Other languages
English (en)
Inventor
Piet Tom Bert Paul Wigerinck
Wim Gaston Verschueren
Marc Francis Josephin Schroven
Bruyn Marcel Frans Leopold De
Original Assignee
Janssen Pharmaceutica Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Janssen Pharmaceutica Nv filed Critical Janssen Pharmaceutica Nv
Application granted granted Critical
Publication of ATE334125T1 publication Critical patent/ATE334125T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nutrition Science (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
AT98966603T 1997-12-05 1998-11-27 (benzodioxan, benzofuran, oder benzopyran) derivate mit fundic entspannungseigenschaften ATE334125T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP97203808 1997-12-05

Publications (1)

Publication Number Publication Date
ATE334125T1 true ATE334125T1 (de) 2006-08-15

Family

ID=8229014

Family Applications (1)

Application Number Title Priority Date Filing Date
AT98966603T ATE334125T1 (de) 1997-12-05 1998-11-27 (benzodioxan, benzofuran, oder benzopyran) derivate mit fundic entspannungseigenschaften

Country Status (32)

Country Link
US (4) US6133277A (de)
EP (1) EP1036073B8 (de)
JP (1) JP2001525407A (de)
KR (1) KR100591605B1 (de)
CN (1) CN1155597C (de)
AR (1) AR017195A1 (de)
AT (1) ATE334125T1 (de)
AU (1) AU748669B2 (de)
BG (1) BG64624B1 (de)
BR (1) BR9814256A (de)
CA (1) CA2311669C (de)
CO (1) CO5011114A1 (de)
CZ (1) CZ297895B6 (de)
DE (1) DE69835372T2 (de)
EA (1) EA003365B1 (de)
EE (1) EE04438B1 (de)
ES (1) ES2270541T3 (de)
HK (1) HK1028400A1 (de)
HR (1) HRP20000340B1 (de)
HU (1) HU224813B1 (de)
ID (1) ID24616A (de)
IL (1) IL136529A (de)
MY (1) MY124586A (de)
NO (1) NO320727B1 (de)
NZ (1) NZ503603A (de)
PL (1) PL191144B1 (de)
SK (1) SK286268B6 (de)
TR (1) TR200001542T2 (de)
TW (1) TW577886B (de)
UA (1) UA70308C2 (de)
WO (1) WO1999029687A1 (de)
ZA (1) ZA9811081B (de)

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US6133277A (en) * 1997-12-05 2000-10-17 Janssen Pharmaceutica N.V. (Benzodioxan, benzofuran or benzopyran) derivatives having fundic relaxation properties
CZ20014167A3 (cs) * 1999-06-02 2002-06-12 Janssen Pharmaceutica N. V. Pyrrolidinylem, piperidinylem nebo homopiperidinylem substituované deriváty benzodioxanu, benzofuranu nebo benzopyranu
HUP0201404A3 (en) * 1999-06-02 2005-02-28 Janssen Pharmaceutica Nv Aminoalkyl substituted benzodioxan, benzofuran or benzopyran derivatives, pharmaceutical compositions containing them and their use and process for their preparations
JO2352B1 (en) 2000-06-22 2006-12-12 جانسين فارماسيوتيكا ان. في Compounds for the treatment of non-adaptation of the bottom of the uterus
JO2654B1 (en) * 2000-09-04 2012-06-17 شركة جانسين فارماسوتيكا ان. في Multiple aryl caroxa amides are useful as lipid - lowering agents
JO2409B1 (en) 2000-11-21 2007-06-17 شركة جانسين فارماسوتيكا ان. في Second-phenyl carboxy amides are useful as lipid-lowering agents
US6688079B2 (en) 2001-04-18 2004-02-10 Kraft Foods Holdings, Inc. Method for manufacturing flexible packages having slide closures
JPWO2003040382A1 (ja) * 2001-11-09 2005-03-03 株式会社カネカ 光学活性クロマン誘導体の製造法および中間体
ES2199086B1 (es) 2002-07-31 2005-06-01 Cepa Schwarz Pharma Sl Nuevos derivados de cicloalcanodionas, procedimiento para su preparacion y sus aplicaciones farmacologicas.
US7071821B2 (en) * 2003-05-14 2006-07-04 Bellsouth Intellectual Property Corporation Method and system for alerting a person to a situation
ITTO20030140U1 (it) * 2003-09-16 2005-03-17 Interfila Srl Matita cosmetica
US7470798B2 (en) 2003-09-19 2008-12-30 Edison Pharmaceuticals, Inc. 7,8-bicycloalkyl-chroman derivatives
EP1687277B1 (de) 2003-11-20 2018-04-04 Janssen Pharmaceutica NV 6-alkenyl- und 6-phenylalkylsubstituierte 2-chinolinone und 2-chinoxalinone als poly(adp-ribose)-polymerase-inhibitoren
MXPA06005686A (es) 2003-11-20 2006-08-17 Janssen Pharmaceutica Nv 2-quinolinonas y 2-quinoxalinonas 7-fenilaquilo sustituidas como inhibidores de la poli(adp-ribosa)polimerasa.
ES2238015B1 (es) * 2004-01-30 2006-11-01 Cepa Schwarz Pharma, S.L. Derivados de cicloalcanodionas con actividad neuroprotectora.
US7803795B2 (en) 2004-06-30 2010-09-28 Janssen Pharmaceutica N.V. Phthalazine derivatives as parp inhibitors
UA86237C2 (uk) 2004-06-30 2009-04-10 Янссен Фармацевтика Н.В. Похідні заміщеного 2-алкілхіназолінону як інгібітори parp
CN1980913B (zh) 2004-06-30 2011-12-14 詹森药业有限公司 作为parp抑制剂的喹唑啉二酮衍生物
DE102004032277A1 (de) * 2004-07-02 2006-01-19 Basell Polyolefine Gmbh Verfahren zur racemoselektiven Synthese von ansa-Metallocenen
CA2597616A1 (en) 2005-02-17 2006-08-24 Wyeth Cycloalkylfused indole, benzothiophene, benzofuran and indene derivatives
TW200716595A (en) * 2005-04-22 2007-05-01 Wyeth Corp Chromane and chromene derivatives and uses thereof
WO2008015538A2 (en) * 2006-07-31 2008-02-07 Schwarz Pharma S.L. Use of diaza- and thiaza-cycloalkanediones for preventing and/or treating pain and /or migraine
US20080033050A1 (en) 2006-08-04 2008-02-07 Richards Patricia Allison Tewe Method of treating thermoregulatory disfunction with paroxetine
US8503431B2 (en) * 2006-08-25 2013-08-06 Wireless Wonders Ltd. Mobile phone related indirect communication system and method
EP2134691B1 (de) 2007-03-08 2012-01-25 Janssen Pharmaceutica, N.V. Chinolinonderivate als parp und tank-inhibitoren
JP5017703B2 (ja) * 2007-05-16 2012-09-05 住友ゴム工業株式会社 ビードエイペックスおよびタイヤ
US8404713B2 (en) 2007-10-26 2013-03-26 Janssen Pharmaceutica Nv Quinolinone derivatives as PARP inhibitors
AU2009228945B2 (en) 2008-03-27 2013-05-02 Janssen Pharmaceutica Nv Quinazolinone derivatives as tubulin polymerization inhibitors
CN101981013B (zh) 2008-03-27 2013-05-29 詹森药业有限公司 作为parp和微管蛋白聚合抑制剂的四氢菲啶酮和四氢环戊二烯并喹啉酮
HUE046172T2 (hu) 2012-02-24 2020-02-28 Lupin Ltd Szubsztituált krománvegyületek mint kalcium-szenzor receptor modulátorok
US9040533B2 (en) 2012-12-27 2015-05-26 Purdue Pharma L.P. Oxime-substituted-quinoxaline-type piperidine compounds as ORL-1 modulators
DE102013207163B4 (de) 2013-04-19 2022-09-22 Adidas Ag Schuhoberteil
DE102014220087B4 (de) 2014-10-02 2016-05-12 Adidas Ag Flachgestricktes Schuhoberteil für Sportschuhe
US20190290656A1 (en) 2015-12-30 2019-09-26 Yissum Research Development Company Of The Hebrew University Of Jerusalem Ltd Pt(iv) prodrugs

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US3910930A (en) * 1973-01-04 1975-10-07 Janssen Pharmaceutica Nv 1-{55 1-{8 2-(1,4-Benzodioxan-2-yl)-2-hydroxyethyl{9 -4-piperidyl{56 -2-benzimidazolinones
US3929801A (en) * 1973-11-20 1975-12-30 Janssen Pharmaceutica Nv 2-Benzimidazolinones
GB1599296A (en) * 1977-07-06 1981-09-30 Brewster D L Ice making machine
GR71865B (de) * 1978-03-20 1983-07-07 Ciba Geigy
DE2852945A1 (de) * 1978-12-07 1980-06-26 Boehringer Sohn Ingelheim Benzodioxanyl-hydroxyaethylpiperidyl- imidazolidinone, verfahren zu ihrer herstellung und diese enthaltende arzneimittel
US4329348A (en) * 1979-02-26 1982-05-11 Ciba-Geigy Corporation N-Oxacyclic-alkylpiperidines as psychostimulants
US4239348A (en) * 1979-11-30 1980-12-16 Hughes Aircraft Company High resolution AC silicon MOS light-valve substrate
DE3901814A1 (de) * 1988-07-28 1990-02-01 Bayer Ag Substituierte aminomethylzetraline sowie ihre heterocyclischen analoga
DE4140540A1 (de) * 1991-12-09 1993-06-17 Bayer Ag Neue azaheterocyclylmethyl-chromane
SI9300097B (en) * 1992-02-27 2001-12-31 Janssen Pharmaceutica Nv (benzodioxan, benzofuran or benzopyran) alkylamino) alkyl substituted guanidines
DE4319038A1 (de) * 1993-06-08 1994-12-15 Bayer Ag Verwendung von teilweise bekannten substituierten Chromanen als Arzneimittel, neue Wirkstoffe und Verfahren zu ihrer Herstellung
PL181385B1 (pl) * 1993-08-19 2001-07-31 Janssen Pharmaceutica Nv Nowe pochodne dihydrobenzopiranu o wlasciwosciach naczyniozwezajacych, kompozycja farmaceutyczna i sposób wytwarzania pochodnych dihydrobenzopiranu PL PL PL PL PL PL
US5541199A (en) * 1995-06-02 1996-07-30 American Home Products Corporation Chroman-2-ylmethylamino derivatives
FR2744451B1 (fr) * 1996-02-01 1998-04-24 Pf Medicament Nouvelles imidazolidinones, pyrimidinones, et 1,3-diazepin-2 -ones, leur preparation et leurs applications en therapeutique
US5696653A (en) * 1996-12-13 1997-12-09 Phase Metrics Tooling for holding a head gimbal assembly
US6133277A (en) 1997-12-05 2000-10-17 Janssen Pharmaceutica N.V. (Benzodioxan, benzofuran or benzopyran) derivatives having fundic relaxation properties

Also Published As

Publication number Publication date
BR9814256A (pt) 2000-10-03
PL341007A1 (en) 2001-03-12
NO20002074D0 (no) 2000-04-19
TW577886B (en) 2004-03-01
TR200001542T2 (tr) 2001-01-22
EA003365B1 (ru) 2003-04-24
CA2311669A1 (en) 1999-06-17
HU224813B1 (en) 2006-02-28
US20030083365A1 (en) 2003-05-01
BG104372A (en) 2000-12-29
WO1999029687A8 (en) 2000-04-13
IL136529A (en) 2003-03-12
ES2270541T3 (es) 2007-04-01
EP1036073A1 (de) 2000-09-20
IL136529A0 (en) 2001-06-14
AR017195A1 (es) 2001-08-22
NO20002074L (no) 2000-06-02
KR20010031010A (ko) 2001-04-16
KR100591605B1 (ko) 2006-06-20
DE69835372T2 (de) 2007-08-09
HRP20000340A2 (en) 2001-04-30
EP1036073B1 (de) 2006-07-26
US6495547B1 (en) 2002-12-17
SK8032000A3 (en) 2001-02-12
AU748669B2 (en) 2002-06-06
ID24616A (id) 2000-07-27
SK286268B6 (sk) 2008-06-06
AU2412799A (en) 1999-06-28
ZA9811081B (en) 2000-06-22
US20030149093A1 (en) 2003-08-07
CA2311669C (en) 2010-04-27
HUP0004492A2 (hu) 2002-03-28
US6747045B2 (en) 2004-06-08
UA70308C2 (uk) 2004-10-15
NO320727B1 (no) 2006-01-23
CZ20002018A3 (cs) 2000-10-11
EP1036073B8 (de) 2006-11-15
CN1155597C (zh) 2004-06-30
EA200000616A1 (ru) 2000-12-25
WO1999029687A1 (en) 1999-06-17
HK1028400A1 (en) 2001-02-16
EE200000328A (et) 2001-08-15
DE69835372D1 (de) 2006-09-07
CZ297895B6 (cs) 2007-04-25
EE04438B1 (et) 2005-02-15
CO5011114A1 (es) 2001-02-28
PL191144B1 (pl) 2006-03-31
JP2001525407A (ja) 2001-12-11
CN1280577A (zh) 2001-01-17
HUP0004492A3 (en) 2002-04-29
NZ503603A (en) 2001-10-26
MY124586A (en) 2006-06-30
BG64624B1 (bg) 2005-09-30
US6852714B2 (en) 2005-02-08
US6133277A (en) 2000-10-17
HRP20000340B1 (en) 2008-12-31

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Legal Events

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RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties