IL136529A - Benzodioxan, benzofuran or benzopyran derivatives having fundic relaxation properties, their preparation and pharmaceutical compositions containing them - Google Patents

Benzodioxan, benzofuran or benzopyran derivatives having fundic relaxation properties, their preparation and pharmaceutical compositions containing them

Info

Publication number
IL136529A
IL136529A IL13652998A IL13652998A IL136529A IL 136529 A IL136529 A IL 136529A IL 13652998 A IL13652998 A IL 13652998A IL 13652998 A IL13652998 A IL 13652998A IL 136529 A IL136529 A IL 136529A
Authority
IL
Israel
Prior art keywords
benzodioxan
benzofuran
preparation
pharmaceutical compositions
compositions containing
Prior art date
Application number
IL13652998A
Other languages
English (en)
Other versions
IL136529A0 (en
Original Assignee
Janssen Pharmaceutica Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Janssen Pharmaceutica Nv filed Critical Janssen Pharmaceutica Nv
Publication of IL136529A0 publication Critical patent/IL136529A0/xx
Publication of IL136529A publication Critical patent/IL136529A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nutrition Science (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
IL13652998A 1997-12-05 1998-11-27 Benzodioxan, benzofuran or benzopyran derivatives having fundic relaxation properties, their preparation and pharmaceutical compositions containing them IL136529A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP97203808 1997-12-05
PCT/EP1998/007771 WO1999029687A1 (en) 1997-12-05 1998-11-27 (benzodioxan, benzofuran or benzopyran) derivatives having fundic relaxation properties

Publications (2)

Publication Number Publication Date
IL136529A0 IL136529A0 (en) 2001-06-14
IL136529A true IL136529A (en) 2003-03-12

Family

ID=8229014

Family Applications (1)

Application Number Title Priority Date Filing Date
IL13652998A IL136529A (en) 1997-12-05 1998-11-27 Benzodioxan, benzofuran or benzopyran derivatives having fundic relaxation properties, their preparation and pharmaceutical compositions containing them

Country Status (32)

Country Link
US (4) US6133277A (xx)
EP (1) EP1036073B8 (xx)
JP (1) JP2001525407A (xx)
KR (1) KR100591605B1 (xx)
CN (1) CN1155597C (xx)
AR (1) AR017195A1 (xx)
AT (1) ATE334125T1 (xx)
AU (1) AU748669B2 (xx)
BG (1) BG64624B1 (xx)
BR (1) BR9814256A (xx)
CA (1) CA2311669C (xx)
CO (1) CO5011114A1 (xx)
CZ (1) CZ297895B6 (xx)
DE (1) DE69835372T2 (xx)
EA (1) EA003365B1 (xx)
EE (1) EE04438B1 (xx)
ES (1) ES2270541T3 (xx)
HK (1) HK1028400A1 (xx)
HR (1) HRP20000340B1 (xx)
HU (1) HU224813B1 (xx)
ID (1) ID24616A (xx)
IL (1) IL136529A (xx)
MY (1) MY124586A (xx)
NO (1) NO320727B1 (xx)
NZ (1) NZ503603A (xx)
PL (1) PL191144B1 (xx)
SK (1) SK286268B6 (xx)
TR (1) TR200001542T2 (xx)
TW (1) TW577886B (xx)
UA (1) UA70308C2 (xx)
WO (1) WO1999029687A1 (xx)
ZA (1) ZA9811081B (xx)

Families Citing this family (34)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6133277A (en) 1997-12-05 2000-10-17 Janssen Pharmaceutica N.V. (Benzodioxan, benzofuran or benzopyran) derivatives having fundic relaxation properties
PL198532B1 (pl) * 1999-06-02 2008-06-30 Janssen Pharmaceutica Nv Pochodna benzopiranu podstawiona pirolidynylem, piperydynylem lub homopiperydynylem i sposób jej otrzymywania oraz kompozycja farmaceutyczna i sposób jej otrzymywania
DK1187829T3 (da) * 1999-06-02 2004-04-13 Janssen Pharmaceutica Nv Aminoalkylsubstituerede (benzodioxan, benzofuran eller benzopyran) derivater
JO2352B1 (en) * 2000-06-22 2006-12-12 جانسين فارماسيوتيكا ان. في Compounds for the treatment of non-adaptation of the bottom of the uterus
JO2654B1 (en) 2000-09-04 2012-06-17 شركة جانسين فارماسوتيكا ان. في Multiple aryl caroxa amides are useful as lipid - lowering agents
JO2409B1 (en) * 2000-11-21 2007-06-17 شركة جانسين فارماسوتيكا ان. في Second-phenyl carboxy amides are useful as lipid-lowering agents
US6688079B2 (en) 2001-04-18 2004-02-10 Kraft Foods Holdings, Inc. Method for manufacturing flexible packages having slide closures
US20050014818A1 (en) * 2001-11-09 2005-01-20 Masaru Mitsuda Process for producing optically active chroman derivative and intermediate
ES2199086B1 (es) 2002-07-31 2005-06-01 Cepa Schwarz Pharma Sl Nuevos derivados de cicloalcanodionas, procedimiento para su preparacion y sus aplicaciones farmacologicas.
US7071821B2 (en) * 2003-05-14 2006-07-04 Bellsouth Intellectual Property Corporation Method and system for alerting a person to a situation
ITTO20030140U1 (it) * 2003-09-16 2005-03-17 Interfila Srl Matita cosmetica
WO2005032544A1 (en) 2003-09-19 2005-04-14 Galileo Pharmaceuticals, Inc. Treatment of mitochondrial diseases
EP1687277B1 (en) 2003-11-20 2018-04-04 Janssen Pharmaceutica NV 6-alkenyl and 6-phenylalkyl substituted 2-quinolinones and 2-quinoxalinones as poly(adp-ribose) polymerase inhibitors
CN1882549B (zh) 2003-11-20 2011-02-23 詹森药业有限公司 用作聚(adp-核糖)聚合酶抑制剂的7-苯基烷基取代的2-喹啉酮和2-喹喔啉酮
ES2238015B1 (es) * 2004-01-30 2006-11-01 Cepa Schwarz Pharma, S.L. Derivados de cicloalcanodionas con actividad neuroprotectora.
EP1771175B1 (en) 2004-06-30 2015-12-23 Janssen Pharmaceutica NV Phthalazine derivatives as parp inhibitors
NZ551801A (en) * 2004-06-30 2009-11-27 Janssen Pharmaceutica Nv Quinazolinedione derivatives as PARP inhibitors
AU2005259188B2 (en) 2004-06-30 2011-03-31 Janssen Pharmaceutica N.V. Quinazolinone derivatives as PARP inhibitors
DE102004032277A1 (de) * 2004-07-02 2006-01-19 Basell Polyolefine Gmbh Verfahren zur racemoselektiven Synthese von ansa-Metallocenen
JP2008530229A (ja) 2005-02-17 2008-08-07 ワイス シクロアルキル縮合インドール、ベンゾチオフェン、ベンゾフランおよびインデン誘導体
RU2007139541A (ru) * 2005-04-22 2009-05-27 Вайет (Us) Производные хромана и хромена и их применение
WO2008015538A2 (en) * 2006-07-31 2008-02-07 Schwarz Pharma S.L. Use of diaza- and thiaza-cycloalkanediones for preventing and/or treating pain and /or migraine
US20080033050A1 (en) 2006-08-04 2008-02-07 Richards Patricia Allison Tewe Method of treating thermoregulatory disfunction with paroxetine
US8503431B2 (en) * 2006-08-25 2013-08-06 Wireless Wonders Ltd. Mobile phone related indirect communication system and method
DK2134691T3 (da) 2007-03-08 2012-05-07 Janssen Pharmaceutica Nv Quinolinonderivativer som parp- og tank-inhibitorer
JP5017703B2 (ja) * 2007-05-16 2012-09-05 住友ゴム工業株式会社 ビードエイペックスおよびタイヤ
ES2448870T3 (es) 2007-10-26 2014-03-17 Janssen Pharmaceutica, N.V. Derivados de quinolina como inhibidores de PARP
ATE513818T1 (de) 2008-03-27 2011-07-15 Janssen Pharmaceutica Nv Chinazolinonderivate als tubulinpolymerisationshemmer
EP2271626B1 (en) 2008-03-27 2014-11-26 Janssen Pharmaceutica, N.V. Tetrahydrophenanthridinones and tetrahydrocyclopentaquinolinones as parp and tubulin polymerization inhibitors
RS59172B1 (sr) 2012-02-24 2019-10-31 Lupin Ltd Supstituisana jedinjenja hromana kao modulatori receptora osetljivog na kalcijum
US9040533B2 (en) 2012-12-27 2015-05-26 Purdue Pharma L.P. Oxime-substituted-quinoxaline-type piperidine compounds as ORL-1 modulators
DE102013207163B4 (de) 2013-04-19 2022-09-22 Adidas Ag Schuhoberteil
DE102014220087B4 (de) 2014-10-02 2016-05-12 Adidas Ag Flachgestricktes Schuhoberteil für Sportschuhe
WO2017115372A1 (en) 2015-12-30 2017-07-06 Yissum Research Development Company Of The Hebrew University Of Jerusalem Ltd Pt(IV) PRODRUGS

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3910930A (en) * 1973-01-04 1975-10-07 Janssen Pharmaceutica Nv 1-{55 1-{8 2-(1,4-Benzodioxan-2-yl)-2-hydroxyethyl{9 -4-piperidyl{56 -2-benzimidazolinones
US3929801A (en) * 1973-11-20 1975-12-30 Janssen Pharmaceutica Nv 2-Benzimidazolinones
GB1599296A (en) * 1977-07-06 1981-09-30 Brewster D L Ice making machine
GR71865B (xx) * 1978-03-20 1983-07-07 Ciba Geigy
DE2852945A1 (de) * 1978-12-07 1980-06-26 Boehringer Sohn Ingelheim Benzodioxanyl-hydroxyaethylpiperidyl- imidazolidinone, verfahren zu ihrer herstellung und diese enthaltende arzneimittel
US4329348A (en) * 1979-02-26 1982-05-11 Ciba-Geigy Corporation N-Oxacyclic-alkylpiperidines as psychostimulants
US4239348A (en) * 1979-11-30 1980-12-16 Hughes Aircraft Company High resolution AC silicon MOS light-valve substrate
DE3901814A1 (de) * 1988-07-28 1990-02-01 Bayer Ag Substituierte aminomethylzetraline sowie ihre heterocyclischen analoga
DE4140540A1 (de) * 1991-12-09 1993-06-17 Bayer Ag Neue azaheterocyclylmethyl-chromane
SI9300097B (en) * 1992-02-27 2001-12-31 Janssen Pharmaceutica Nv (benzodioxan, benzofuran or benzopyran) alkylamino) alkyl substituted guanidines
DE4319038A1 (de) * 1993-06-08 1994-12-15 Bayer Ag Verwendung von teilweise bekannten substituierten Chromanen als Arzneimittel, neue Wirkstoffe und Verfahren zu ihrer Herstellung
CN1052006C (zh) * 1993-08-19 2000-05-03 詹森药业有限公司 血管收缩剂二氢苯并吡喃衍生物,制备方法和用途
US5541199A (en) * 1995-06-02 1996-07-30 American Home Products Corporation Chroman-2-ylmethylamino derivatives
FR2744451B1 (fr) * 1996-02-01 1998-04-24 Pf Medicament Nouvelles imidazolidinones, pyrimidinones, et 1,3-diazepin-2 -ones, leur preparation et leurs applications en therapeutique
US5696653A (en) * 1996-12-13 1997-12-09 Phase Metrics Tooling for holding a head gimbal assembly
US6133277A (en) * 1997-12-05 2000-10-17 Janssen Pharmaceutica N.V. (Benzodioxan, benzofuran or benzopyran) derivatives having fundic relaxation properties

Also Published As

Publication number Publication date
EP1036073B8 (en) 2006-11-15
US6852714B2 (en) 2005-02-08
EE200000328A (et) 2001-08-15
UA70308C2 (uk) 2004-10-15
US20030149093A1 (en) 2003-08-07
AU748669B2 (en) 2002-06-06
DE69835372D1 (de) 2006-09-07
EA200000616A1 (ru) 2000-12-25
CZ297895B6 (cs) 2007-04-25
EP1036073A1 (en) 2000-09-20
US20030083365A1 (en) 2003-05-01
DE69835372T2 (de) 2007-08-09
EE04438B1 (et) 2005-02-15
CA2311669C (en) 2010-04-27
TW577886B (en) 2004-03-01
PL341007A1 (en) 2001-03-12
CN1280577A (zh) 2001-01-17
KR20010031010A (ko) 2001-04-16
EP1036073B1 (en) 2006-07-26
NO320727B1 (no) 2006-01-23
HRP20000340B1 (en) 2008-12-31
AU2412799A (en) 1999-06-28
PL191144B1 (pl) 2006-03-31
HK1028400A1 (en) 2001-02-16
KR100591605B1 (ko) 2006-06-20
TR200001542T2 (tr) 2001-01-22
BR9814256A (pt) 2000-10-03
NO20002074L (no) 2000-06-02
HUP0004492A2 (hu) 2002-03-28
HUP0004492A3 (en) 2002-04-29
CN1155597C (zh) 2004-06-30
AR017195A1 (es) 2001-08-22
WO1999029687A1 (en) 1999-06-17
NO20002074D0 (no) 2000-04-19
CA2311669A1 (en) 1999-06-17
ATE334125T1 (de) 2006-08-15
WO1999029687A8 (en) 2000-04-13
SK286268B6 (sk) 2008-06-06
ES2270541T3 (es) 2007-04-01
NZ503603A (en) 2001-10-26
BG104372A (en) 2000-12-29
US6495547B1 (en) 2002-12-17
US6747045B2 (en) 2004-06-08
CZ20002018A3 (cs) 2000-10-11
IL136529A0 (en) 2001-06-14
SK8032000A3 (en) 2001-02-12
MY124586A (en) 2006-06-30
EA003365B1 (ru) 2003-04-24
JP2001525407A (ja) 2001-12-11
HU224813B1 (en) 2006-02-28
ZA9811081B (en) 2000-06-22
US6133277A (en) 2000-10-17
BG64624B1 (bg) 2005-09-30
ID24616A (id) 2000-07-27
HRP20000340A2 (en) 2001-04-30
CO5011114A1 (es) 2001-02-28

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Legal Events

Date Code Title Description
FF Patent granted
KB Patent renewed
KB Patent renewed
MM9K Patent not in force due to non-payment of renewal fees