EE04438B1 - Bensodioksaani, bensofuraani või bensopüraani derivaadid, nende valmistamismeetod ja kasutamine ning farmatseutiline kompositsioon ja selle valmistamismeetod - Google Patents

Bensodioksaani, bensofuraani või bensopüraani derivaadid, nende valmistamismeetod ja kasutamine ning farmatseutiline kompositsioon ja selle valmistamismeetod

Info

Publication number
EE04438B1
EE04438B1 EEP200000328A EEP200000328A EE04438B1 EE 04438 B1 EE04438 B1 EE 04438B1 EE P200000328 A EEP200000328 A EE P200000328A EE P200000328 A EEP200000328 A EE P200000328A EE 04438 B1 EE04438 B1 EE 04438B1
Authority
EE
Estonia
Prior art keywords
benzodioxane
benzofuran
preparation
pharmaceutical composition
benzopyran derivatives
Prior art date
Application number
EEP200000328A
Other languages
English (en)
Estonian (et)
Inventor
Tom Bert Paul Wigerinck Piet
Gaston Verschueren Wim
Francis Josephine Schroven Marc
Frans Leopold De Bruyn Marcel
Original Assignee
Janssen Pharmaceutica N.V.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Janssen Pharmaceutica N.V. filed Critical Janssen Pharmaceutica N.V.
Publication of EE200000328A publication Critical patent/EE200000328A/xx
Publication of EE04438B1 publication Critical patent/EE04438B1/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nutrition Science (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
EEP200000328A 1997-12-05 1998-11-27 Bensodioksaani, bensofuraani või bensopüraani derivaadid, nende valmistamismeetod ja kasutamine ning farmatseutiline kompositsioon ja selle valmistamismeetod EE04438B1 (et)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP97203808 1997-12-05
PCT/EP1998/007771 WO1999029687A1 (en) 1997-12-05 1998-11-27 (benzodioxan, benzofuran or benzopyran) derivatives having fundic relaxation properties

Publications (2)

Publication Number Publication Date
EE200000328A EE200000328A (et) 2001-08-15
EE04438B1 true EE04438B1 (et) 2005-02-15

Family

ID=8229014

Family Applications (1)

Application Number Title Priority Date Filing Date
EEP200000328A EE04438B1 (et) 1997-12-05 1998-11-27 Bensodioksaani, bensofuraani või bensopüraani derivaadid, nende valmistamismeetod ja kasutamine ning farmatseutiline kompositsioon ja selle valmistamismeetod

Country Status (31)

Country Link
US (4) US6133277A (cs)
EP (1) EP1036073B8 (cs)
JP (1) JP2001525407A (cs)
KR (1) KR100591605B1 (cs)
CN (1) CN1155597C (cs)
AR (1) AR017195A1 (cs)
AT (1) ATE334125T1 (cs)
AU (1) AU748669B2 (cs)
BG (1) BG64624B1 (cs)
BR (1) BR9814256A (cs)
CA (1) CA2311669C (cs)
CO (1) CO5011114A1 (cs)
CZ (1) CZ297895B6 (cs)
DE (1) DE69835372T2 (cs)
EA (1) EA003365B1 (cs)
EE (1) EE04438B1 (cs)
ES (1) ES2270541T3 (cs)
HR (1) HRP20000340B1 (cs)
HU (1) HU224813B1 (cs)
ID (1) ID24616A (cs)
IL (1) IL136529A (cs)
MY (1) MY124586A (cs)
NO (1) NO320727B1 (cs)
NZ (1) NZ503603A (cs)
PL (1) PL191144B1 (cs)
SK (1) SK286268B6 (cs)
TR (1) TR200001542T2 (cs)
TW (1) TW577886B (cs)
UA (1) UA70308C2 (cs)
WO (1) WO1999029687A1 (cs)
ZA (1) ZA9811081B (cs)

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US6133277A (en) 1997-12-05 2000-10-17 Janssen Pharmaceutica N.V. (Benzodioxan, benzofuran or benzopyran) derivatives having fundic relaxation properties
CA2374905C (en) * 1999-06-02 2010-02-23 Janssen Pharmaceutica N.V. Pyrrolidinyl, piperidinyl or homopiperidinyl-substituted benzopyran derivatives for treating impaired fundic relaxation
WO2000075136A1 (en) * 1999-06-02 2000-12-14 Janssen Pharmaceutica N.V. Aminoalkyl substituted (benzodioxan, benzofuran or benzopyran) derivatives
JO2352B1 (en) 2000-06-22 2006-12-12 جانسين فارماسيوتيكا ان. في Compounds for the treatment of non-adaptation of the bottom of the uterus
JO2654B1 (en) * 2000-09-04 2012-06-17 شركة جانسين فارماسوتيكا ان. في Multiple aryl caroxa amides are useful as lipid - lowering agents
JO2409B1 (en) 2000-11-21 2007-06-17 شركة جانسين فارماسوتيكا ان. في Second-phenyl carboxy amides are useful as lipid-lowering agents
US6688079B2 (en) 2001-04-18 2004-02-10 Kraft Foods Holdings, Inc. Method for manufacturing flexible packages having slide closures
EP1445324A4 (en) * 2001-11-09 2005-02-16 Kaneka Corp PROCESS FOR PRODUCING OPTICALLY ACTIVE CHROMAN DERIVATIVE AND INTERMEDIATE PRODUCT
ES2199086B1 (es) 2002-07-31 2005-06-01 Cepa Schwarz Pharma Sl Nuevos derivados de cicloalcanodionas, procedimiento para su preparacion y sus aplicaciones farmacologicas.
US7071821B2 (en) * 2003-05-14 2006-07-04 Bellsouth Intellectual Property Corporation Method and system for alerting a person to a situation
ITTO20030140U1 (it) * 2003-09-16 2005-03-17 Interfila Srl Matita cosmetica
US7514461B2 (en) * 2003-09-19 2009-04-07 Edison Pharmaceuticals, Inc. Chroman derivatives
CN1882549B (zh) 2003-11-20 2011-02-23 詹森药业有限公司 用作聚(adp-核糖)聚合酶抑制剂的7-苯基烷基取代的2-喹啉酮和2-喹喔啉酮
SG150533A1 (en) 2003-11-20 2009-03-30 Janssen Pharmaceutica Nv 6-alkenyl and 6-phenylalkyl substituted 2-quinolinones and 2- quinoxalinones as poly(adp-ribose) polymerase inhibitors
ES2238015B1 (es) * 2004-01-30 2006-11-01 Cepa Schwarz Pharma, S.L. Derivados de cicloalcanodionas con actividad neuroprotectora.
JP4969443B2 (ja) 2004-06-30 2012-07-04 ジヤンセン・フアーマシユーチカ・ナームローゼ・フエンノートシヤツプ Ｐａｒｐ阻害剤としてのキナゾリノン誘導体
WO2006003147A1 (en) 2004-06-30 2006-01-12 Janssen Pharmaceutica N.V. Phthalazine derivatives as parp inhibitors
UA88012C2 (uk) * 2004-06-30 2009-09-10 Янссен Фармацевтика Н.В. Похідні хіназоліндіону як інгібітори parp
JP2008504331A (ja) * 2004-07-02 2008-02-14 バーゼル、ポリオレフィン、ゲゼルシャフト、ミット、ベシュレンクテル、ハフツング アンサ−メタロセンをラセモ選択的に合成する方法
DE102004032277A1 (de) * 2004-07-02 2006-01-19 Basell Polyolefine Gmbh Verfahren zur racemoselektiven Synthese von ansa-Metallocenen
PA8663501A1 (es) 2005-02-17 2006-11-09 Wyeth Wyeth Derivados de indol, benzotiofeno, benzofurano e indeno cicloalquilcondensados
RU2007139541A (ru) * 2005-04-22 2009-05-27 Вайет (Us) Производные хромана и хромена и их применение
WO2008015538A2 (en) * 2006-07-31 2008-02-07 Schwarz Pharma S.L. Use of diaza- and thiaza-cycloalkanediones for preventing and/or treating pain and /or migraine
US20080033050A1 (en) 2006-08-04 2008-02-07 Richards Patricia Allison Tewe Method of treating thermoregulatory disfunction with paroxetine
US8503431B2 (en) * 2006-08-25 2013-08-06 Wireless Wonders Ltd. Mobile phone related indirect communication system and method
WO2008107478A1 (en) 2007-03-08 2008-09-12 Janssen Pharmaceutica Nv Quinolinone derivatives as parp and tank inhibitors
JP5017703B2 (ja) * 2007-05-16 2012-09-05 住友ゴム工業株式会社 ビードエイペックスおよびタイヤ
PL2215075T3 (pl) 2007-10-26 2014-04-30 Janssen Pharmaceutica Nv Pochodne chinolinonu jako inhibitory PARP
WO2009118382A1 (en) 2008-03-27 2009-10-01 Janssen Pharmaceutica Nv Tetrahydrophenanthridinones and tetrahydrocyclopentaquinolinones as parp and tubulin polymerization inhibitors
ATE513818T1 (de) 2008-03-27 2011-07-15 Janssen Pharmaceutica Nv Chinazolinonderivate als tubulinpolymerisationshemmer
KR102041154B1 (ko) 2012-02-24 2019-11-07 루핀 리미티드 칼슘 감지 수용체 조절자로서의 치환 크로만 화합물
DE102012206062B4 (de) 2012-04-13 2019-09-12 Adidas Ag Schuhoberteil
WO2014102592A2 (en) 2012-12-27 2014-07-03 Purdue Pharma L.P. Oxime/substituted quinoxaline-type piperidine compounds and uses thereof
DE102013207163B4 (de) 2013-04-19 2022-09-22 Adidas Ag Schuhoberteil
DE102014220087B4 (de) 2014-10-02 2016-05-12 Adidas Ag Flachgestricktes Schuhoberteil für Sportschuhe
CN108713021A (zh) 2015-12-30 2018-10-26 耶路撒冷希伯来大学伊森姆研究发展有限公司 Pt(IV)前药
CN119462701A (zh) * 2024-10-11 2025-02-18 合肥工业大学 一种四吡啶草酸铜金属配合物的制备及用途

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US3929801A (en) * 1973-11-20 1975-12-30 Janssen Pharmaceutica Nv 2-Benzimidazolinones
GB1599296A (en) * 1977-07-06 1981-09-30 Brewster D L Ice making machine
GR71865B (cs) * 1978-03-20 1983-07-07 Ciba Geigy
DE2852945A1 (de) * 1978-12-07 1980-06-26 Boehringer Sohn Ingelheim Benzodioxanyl-hydroxyaethylpiperidyl- imidazolidinone, verfahren zu ihrer herstellung und diese enthaltende arzneimittel
US4329348A (en) * 1979-02-26 1982-05-11 Ciba-Geigy Corporation N-Oxacyclic-alkylpiperidines as psychostimulants
US4239348A (en) * 1979-11-30 1980-12-16 Hughes Aircraft Company High resolution AC silicon MOS light-valve substrate
DE3901814A1 (de) * 1988-07-28 1990-02-01 Bayer Ag Substituierte aminomethylzetraline sowie ihre heterocyclischen analoga
DE4140540A1 (de) * 1991-12-09 1993-06-17 Bayer Ag Neue azaheterocyclylmethyl-chromane
SI9300097B (en) * 1992-02-27 2001-12-31 Janssen Pharmaceutica Nv (benzodioxan, benzofuran or benzopyran) alkylamino) alkyl substituted guanidines
DE4319038A1 (de) * 1993-06-08 1994-12-15 Bayer Ag Verwendung von teilweise bekannten substituierten Chromanen als Arzneimittel, neue Wirkstoffe und Verfahren zu ihrer Herstellung
DE69433401T2 (de) * 1993-08-19 2004-09-16 Janssen Pharmaceutica N.V. Gefässverengende dihydrobenzopyranderivate
US5541199A (en) * 1995-06-02 1996-07-30 American Home Products Corporation Chroman-2-ylmethylamino derivatives
FR2744451B1 (fr) * 1996-02-01 1998-04-24 Pf Medicament Nouvelles imidazolidinones, pyrimidinones, et 1,3-diazepin-2 -ones, leur preparation et leurs applications en therapeutique
US5696653A (en) * 1996-12-13 1997-12-09 Phase Metrics Tooling for holding a head gimbal assembly
US6133277A (en) * 1997-12-05 2000-10-17 Janssen Pharmaceutica N.V. (Benzodioxan, benzofuran or benzopyran) derivatives having fundic relaxation properties

Also Published As

Publication number Publication date
JP2001525407A (ja) 2001-12-11
EA003365B1 (ru) 2003-04-24
WO1999029687A8 (en) 2000-04-13
ATE334125T1 (de) 2006-08-15
BG104372A (en) 2000-12-29
UA70308C2 (uk) 2004-10-15
PL341007A1 (en) 2001-03-12
EP1036073A1 (en) 2000-09-20
US6852714B2 (en) 2005-02-08
EP1036073B1 (en) 2006-07-26
KR20010031010A (ko) 2001-04-16
NO320727B1 (no) 2006-01-23
ID24616A (id) 2000-07-27
DE69835372T2 (de) 2007-08-09
EA200000616A1 (ru) 2000-12-25
ZA9811081B (en) 2000-06-22
IL136529A (en) 2003-03-12
HUP0004492A2 (hu) 2002-03-28
SK286268B6 (sk) 2008-06-06
US20030083365A1 (en) 2003-05-01
TW577886B (en) 2004-03-01
CA2311669C (en) 2010-04-27
EP1036073B8 (en) 2006-11-15
US6747045B2 (en) 2004-06-08
NZ503603A (en) 2001-10-26
BR9814256A (pt) 2000-10-03
CA2311669A1 (en) 1999-06-17
NO20002074D0 (no) 2000-04-19
HUP0004492A3 (en) 2002-04-29
TR200001542T2 (tr) 2001-01-22
BG64624B1 (bg) 2005-09-30
CZ20002018A3 (cs) 2000-10-11
HRP20000340B1 (hr) 2008-12-31
AU748669B2 (en) 2002-06-06
HRP20000340A2 (en) 2001-04-30
PL191144B1 (pl) 2006-03-31
KR100591605B1 (ko) 2006-06-20
IL136529A0 (en) 2001-06-14
CZ297895B6 (cs) 2007-04-25
WO1999029687A1 (en) 1999-06-17
EE200000328A (et) 2001-08-15
CN1155597C (zh) 2004-06-30
US6495547B1 (en) 2002-12-17
AR017195A1 (es) 2001-08-22
ES2270541T3 (es) 2007-04-01
US6133277A (en) 2000-10-17
AU2412799A (en) 1999-06-28
SK8032000A3 (en) 2001-02-12
MY124586A (en) 2006-06-30
HK1028400A1 (en) 2001-02-16
HU224813B1 (en) 2006-02-28
CO5011114A1 (es) 2001-02-28
DE69835372D1 (de) 2006-09-07
CN1280577A (zh) 2001-01-17
US20030149093A1 (en) 2003-08-07
NO20002074L (no) 2000-06-02

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