ES2048428T3 - Composiciones de ibuprofeno de administracion oral. - Google Patents

Composiciones de ibuprofeno de administracion oral.

Info

Publication number
ES2048428T3
ES2048428T3 ES90302750T ES90302750T ES2048428T3 ES 2048428 T3 ES2048428 T3 ES 2048428T3 ES 90302750 T ES90302750 T ES 90302750T ES 90302750 T ES90302750 T ES 90302750T ES 2048428 T3 ES2048428 T3 ES 2048428T3
Authority
ES
Spain
Prior art keywords
composition
oral administration
volume
weight
sample
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES90302750T
Other languages
English (en)
Inventor
Solomon Motola
Annabelle Mogavero
Gary R Agisim
Pamela N Panopoulos
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Wyeth LLC
Original Assignee
American Home Products Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by American Home Products Corp filed Critical American Home Products Corp
Application granted granted Critical
Publication of ES2048428T3 publication Critical patent/ES2048428T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
    • A61K9/0095—Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)

Abstract

EL INVENTO CONCIERNE A UNA COMPOSICION IBUPROFEN DE BASE ACUOSA, NEUTRAL DE MUESTRA CONVENIENTE PARA ADMINISTRACION ORAL, QUE COMPRENDE SUSPENDER EL CONTENIDO DE IBUPROFEN DE 0.8 AL 4% DE PESO POR VOLUMEN DE LA COMPOSICION TOTAL, COMPRENDIENDO UNA SUSPENSION PRIMARIA QUE ESTABILIZA LA COMBINACION DE LOS INGREDIENTES QUE COMPRENDEN EL 0.1 AL 2% DE PESO DE LA SUSPENSION QUE ESTABILIZA LA COMBINACION POR VOLUMEN DE LA COMPOSICION TOTAL; LA MUESTRA QUE ENMASCARA LA COMBINACION COMPRENDE DEL 20 AL 70% DE PESO DE LA MUESTRA QUE ENMASCARA LA COMBINACION POR VOLUMEN DE LA COMPOSICION TOTAL; LA COMPOSICION TAMBIEN CONTIENE UNO O MAS ACIDOS AMORTIGUADORES EN UNA CANTIDAD SUFICIENTE PARA AJUSTAR EL PH A 1.5 A 3.5 Y PARA PROVEER UNA CAPACIDAD AMORTIGUADORA DENTRO DEL RANGO DE 0.03 A 0.05 ENTRE EL PH INICIAL Y UN PH QUE ES 1.0 UNIDAD PH MAS ALTA QUE EL PH INICIAL, Y AGUA QS A 100% DE VOLUMEN DE LA COMPOSICION.
ES90302750T 1989-03-28 1990-03-15 Composiciones de ibuprofeno de administracion oral. Expired - Lifetime ES2048428T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/329,624 US4975465A (en) 1989-03-28 1989-03-28 Orally administrable ibuprofen compositions

Publications (1)

Publication Number Publication Date
ES2048428T3 true ES2048428T3 (es) 1994-03-16

Family

ID=23286273

Family Applications (1)

Application Number Title Priority Date Filing Date
ES90302750T Expired - Lifetime ES2048428T3 (es) 1989-03-28 1990-03-15 Composiciones de ibuprofeno de administracion oral.

Country Status (15)

Country Link
US (1) US4975465A (es)
EP (1) EP0390369B1 (es)
JP (1) JP2847134B2 (es)
KR (1) KR0143899B1 (es)
AR (1) AR245366A1 (es)
AT (1) ATE100313T1 (es)
AU (1) AU629622B2 (es)
CA (1) CA1336819C (es)
DE (1) DE69006068T2 (es)
DK (1) DK0390369T3 (es)
ES (1) ES2048428T3 (es)
HK (1) HK68194A (es)
IE (1) IE64024B1 (es)
MX (1) MX173433B (es)
NZ (1) NZ233102A (es)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2003047550A1 (es) * 2001-12-04 2003-06-12 Farmalider, S.A. Composiciones farmaceuticas liquidas de base acuosa en forma de suspension para la administracion por via oral de ibuprofeno

Families Citing this family (37)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5994041A (en) * 1985-04-06 1999-11-30 Eastman Kodak Company Process for buffering concentrated aqueous slurries
NZ234143A (en) * 1989-06-28 1991-10-25 Mcneil Ppc Inc Aqueous pharmaceutical suspension formulation for administering substantially insoluble pharmaceutical agents
US5262179A (en) * 1989-09-13 1993-11-16 Nicholas Kiwi Pty Ltd. Non-effervescent ibuprofen compositions
US5605930A (en) * 1991-10-21 1997-02-25 The United States Of America As Represented By The Department Of Health And Human Services Compositions and methods for treating and preventing pathologies including cancer
US5272137A (en) * 1992-02-14 1993-12-21 Mcneil-Pfc, Inc. Aqueous pharmaceutical suspension for pharmaceutical actives
AU2584092A (en) * 1992-09-03 1994-03-29 Affinity Biotech, Inc. Taste-masking pharmaceutical compositions and methods for making the same
NO941358L (no) * 1993-04-16 1994-10-17 Mcneil Ppc Inc Vandig farmasöytisk suspensjon og fremgangsmåte for fremstilling derav
DE4327147C2 (de) * 1993-08-12 1996-12-19 Klinge Co Chem Pharm Fab Arzneimittelzusammensetzung, welche neben dem Wirkstoff ein Gemisch aus Gelatine unterschiedlicher Löslichkeit enthält
FR2713931B1 (fr) * 1993-12-20 1996-04-05 Laurence Paris Nouvelles compositions pharmaceutiques liquides à base d'ibuprofène et leur procédé de préparation.
US5609998A (en) * 1994-12-29 1997-03-11 Eastman Kodak Company Process for dispersing concentrated aqueous slurries
TW442287B (en) * 1995-06-13 2001-06-23 American Home Produits Corp Organoleptically acceptable oral pharmaceutical composition comprising the S(+)1,8-diethyl-1-1,3,4,9-tetrahydropyrano[3,4-b] indole-1-acetic acid (Etodolac)
AU717764B2 (en) * 1996-05-02 2000-03-30 Taisho Pharmaceutical Co., Ltd. Suspension of sparingly water-soluble acidic drug
GB9625589D0 (en) 1996-12-10 1997-01-29 Boots Co Plc Therapeutic agents
ES2224634T3 (es) 1998-04-29 2005-03-01 Sumitomo Pharmaceuticals Company, Limited Formulacion oral que comprende biguanida y un acido organico.
GB0001315D0 (en) * 2000-01-20 2000-03-08 Novartis Ag Organic compounds
AU2002327418A1 (en) * 2001-08-01 2003-02-17 Bristol-Myers Squibb Company Taste masking composition
US20040132823A1 (en) * 2001-11-02 2004-07-08 Leo Pavliv Pharmaceutical composition of 2-(4-isobutylphenyl) propionic acid
CA2478411C (en) * 2002-03-12 2010-09-28 Bristol-Myers Squibb Company Palatable oral suspension and method
US7300670B2 (en) 2002-04-03 2007-11-27 Unilab Pharmatech, Ltd. Oral suspension formulation
CA2486553C (en) * 2002-06-17 2012-01-10 Taro Pharmaceuticals U.S.A., Inc. Ibuprofen suspension
KR100509432B1 (ko) * 2002-12-13 2005-08-22 주식회사 동구제약 Ｓ(+)-이부프로펜을 함유한 시럽제 조성물 및 그의 제조방법
FR2850275B1 (fr) 2003-01-24 2005-04-08 Scherer Technologies Inc R P Capsules molles a macher contenant une substance active a gout masque
WO2004069132A2 (de) * 2003-02-06 2004-08-19 Gebro Pharma Gmbh Pharmazeutische zubereitungen und verfahren zu deren herstellung
US20040186180A1 (en) * 2003-03-21 2004-09-23 Gelotte Cathy K. Non-steroidal anti-inflammatory drug dosing regimen
CA2542755A1 (en) * 2003-10-17 2005-04-28 Medrx Co., Ltd. Biguanide drug-containing jelly preparation
US20050095299A1 (en) * 2003-10-30 2005-05-05 Wynn David W. Controlled release analgesic suspensions
GB2407497A (en) * 2003-10-30 2005-05-04 John Anthony Walters Method and formulation for the rapid and stable taste-masking of insoluble pharmaceutically active compounds using a surfactant and a hydrocolloid
US20050095300A1 (en) * 2003-10-30 2005-05-05 Wynn David W. Controlled release analgesic suspensions
US20050266031A1 (en) * 2004-05-25 2005-12-01 Jay Dickerson Pharmaceutical suspension composition
EP2522365B1 (en) * 2004-11-24 2016-10-26 Meda Pharmaceuticals Inc. Compositions comprising azelastine and methods of use thereof
MX2009005339A (es) 2006-11-21 2009-06-01 Mcneil Ppc Inc Suspensiones analgesicas de liberacion modificada.
US9833510B2 (en) * 2007-06-12 2017-12-05 Johnson & Johnson Consumer Inc. Modified release solid or semi-solid dosage forms
US8362083B2 (en) * 2008-01-15 2013-01-29 C.B. Fleet Company Inc. Taste-masked docusate compositions
GB201006218D0 (en) * 2010-04-14 2010-06-02 Ayanda As Composition
CA3023121A1 (en) * 2011-04-11 2012-10-18 Vitux Group As Oral pharmaceutical dispersion compositions
US9452135B2 (en) 2012-03-20 2016-09-27 Particle Dynamics International, Llc Gelling agent-based dosage form
AU2020410965B2 (en) * 2019-12-23 2025-12-11 Farmalíder, S.A Liquid composition comprising ibuprofen and phenylephrine

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4145440A (en) * 1977-08-18 1979-03-20 The Upjohn Company Liquid suspension of an aluminum salt of ibuprofen
US4361580A (en) * 1980-06-20 1982-11-30 The Upjohn Manufacturing Company Aluminum ibuprofen pharmaceutical suspensions
US4631580A (en) * 1984-11-09 1986-12-23 John Taube Video-stereoscopic-image-producing system
GB8609566D0 (en) * 1986-04-18 1986-05-21 Boots Co Plc Analgesic method
US4788220A (en) * 1987-07-08 1988-11-29 American Home Products Corporation (Del.) Pediatric ibuprofen compositions

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2003047550A1 (es) * 2001-12-04 2003-06-12 Farmalider, S.A. Composiciones farmaceuticas liquidas de base acuosa en forma de suspension para la administracion por via oral de ibuprofeno
ES2197781A1 (es) * 2001-12-04 2004-01-01 Farmalider Sa Composiciones farmaceuticas liquidas de base acuosa en forma de suspension para la administracion por via oral de ibuprofeno.

Also Published As

Publication number Publication date
MX173433B (es) 1994-03-03
KR0143899B1 (ko) 1998-07-15
HK68194A (en) 1994-07-22
JP2847134B2 (ja) 1999-01-13
CA1336819C (en) 1995-08-29
EP0390369A3 (en) 1991-05-15
EP0390369A2 (en) 1990-10-03
AR245366A1 (es) 1994-01-31
DE69006068T2 (de) 1994-05-11
NZ233102A (en) 1991-08-27
DK0390369T3 (da) 1994-04-11
KR900013952A (ko) 1990-10-22
US4975465A (en) 1990-12-04
IE901119L (en) 1990-09-28
DE69006068D1 (de) 1994-03-03
AU5226990A (en) 1990-10-04
IE64024B1 (en) 1995-06-28
AU629622B2 (en) 1992-10-08
MX20055A (es) 1993-10-01
ATE100313T1 (de) 1994-02-15
JPH02286615A (ja) 1990-11-26
EP0390369B1 (en) 1994-01-19

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