ES2109338T3 - Metodo para separar endotoxinas. - Google Patents
Metodo para separar endotoxinas.Info
- Publication number
- ES2109338T3 ES2109338T3 ES92903332T ES92903332T ES2109338T3 ES 2109338 T3 ES2109338 T3 ES 2109338T3 ES 92903332 T ES92903332 T ES 92903332T ES 92903332 T ES92903332 T ES 92903332T ES 2109338 T3 ES2109338 T3 ES 2109338T3
- Authority
- ES
- Spain
- Prior art keywords
- medicament
- endotoxin
- induced
- endotoxins
- separating
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 239000002158 endotoxin Substances 0.000 title abstract 3
- 239000003814 drug Substances 0.000 abstract 2
- 206010037660 Pyrexia Diseases 0.000 abstract 1
- 230000037396 body weight Effects 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 230000027950 fever generation Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
- A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
- A61K31/198—Alpha-amino acids, e.g. alanine or edetic acid [EDTA]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/155—Amidines (), e.g. guanidine (H2N—C(=NH)—NH2), isourea (N=C(OH)—NH2), isothiourea (—N=C(SH)—NH2)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2/00—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor
- A61L2/0005—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor for pharmaceuticals, biologicals or living parts
- A61L2/0082—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor for pharmaceuticals, biologicals or living parts using chemical substances
- A61L2/0088—Liquid substances
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Oncology (AREA)
- Cardiology (AREA)
- Communicable Diseases (AREA)
- Heart & Thoracic Surgery (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- Immunology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- External Artificial Organs (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Medicinal Preparation (AREA)
Abstract
EL INVENTO EXPONE EL USO DE UN COMPONENTE DE FORM. (I) EN EL QUE X ES UN ENTERO DE 2 A 5 Y A ES UN COMPUESTO DE FORM. (II) O (III) O UN COMPUESTO DE AGMATINA, ADECUADOS PARA LA PREPARACION DE UN MEDICAMENTO UTILIZADO EN EL TRATAMIENTO DE EFECTOS INDUCIDOS POR ENDOTOXINA.LA PREPARACION ESTA DESTINADA PARA QUE REPOSE EN UNA CANTIDAD CORRESPONDIENTE DE 10 A 800, PREFERENTEMENTE DE 10 A 400 MG POR KG DE PESO CORPORAL Y HORA. EL INVENTO TAMBIEN EXPONE: UN METODO PARA EL TRATAMIENTO DE UNA FIEBRE PROVOCADA POR ENDOTOXINAS, EN EL QUE SE ADMINISTRAN EL COMPONENTE O AGMATINA EN LAS CANTIDADES YA MENCIONADAS;UN METODO PARA ELIMINAR ENDOTOXINAS DE DISOLUCIONES IN VITRO; Y UN METODO PARA ENRIQUECERLAS.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
SE9100059A SE468881B (sv) | 1991-01-09 | 1991-01-09 | Anvaendning av vissa foereningar foer framstaellning av laekemedel foer behandling av endotoxininducerade effekter samt saett att avlaegsna endotoxiner ur diverse loesningar |
Publications (1)
Publication Number | Publication Date |
---|---|
ES2109338T3 true ES2109338T3 (es) | 1998-01-16 |
Family
ID=20381566
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES92903332T Expired - Lifetime ES2109338T3 (es) | 1991-01-09 | 1991-12-20 | Metodo para separar endotoxinas. |
ES96104316T Expired - Lifetime ES2163543T3 (es) | 1991-01-09 | 1991-12-20 | Metodo para inhibir los efectos inducidos por endotoxinas. |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES96104316T Expired - Lifetime ES2163543T3 (es) | 1991-01-09 | 1991-12-20 | Metodo para inhibir los efectos inducidos por endotoxinas. |
Country Status (11)
Country | Link |
---|---|
EP (4) | EP0566644B1 (es) |
JP (1) | JP3200604B2 (es) |
AT (2) | ATE204753T1 (es) |
AU (1) | AU9152891A (es) |
DE (2) | DE69223426T2 (es) |
DK (2) | DK0566644T3 (es) |
ES (2) | ES2109338T3 (es) |
GR (1) | GR3025573T3 (es) |
PT (1) | PT715849E (es) |
SE (1) | SE468881B (es) |
WO (1) | WO1992011847A1 (es) |
Families Citing this family (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5436270A (en) * | 1993-04-07 | 1995-07-25 | National Science Council | Method for protecting against endotoxin-induced shock |
US6001878A (en) * | 1994-01-11 | 1999-12-14 | Van Leeuwen; Paulus Aloisius Marie | Method of treating disorders of the animal or human body by administering amino acids |
SE9500778D0 (sv) * | 1995-03-03 | 1995-03-03 | Pharmacia Ab | Process for producing a protein |
SE9603068D0 (sv) | 1996-08-23 | 1996-08-23 | Pharmacia & Upjohn Ab | Process for purifying a protein |
SE9603303D0 (sv) | 1996-09-11 | 1996-09-11 | Pharmacia & Upjohn Ab | Process for purifying a protein |
WO1999008669A1 (en) * | 1997-08-15 | 1999-02-25 | Carolyn Ann Fairbanks | Agmatine as a treatment for neuropathic pain |
US6774102B1 (en) | 1999-09-29 | 2004-08-10 | Gambro Dialysatoren Gmbh & Co. Kg | Extracorporeal endotoxin removal method |
IL161110A0 (en) | 2001-09-28 | 2004-08-31 | Esperion Therapeutics Inc | Prevention and treatment of restenosis by local admistration of drug |
SE526038C2 (sv) * | 2002-07-08 | 2005-06-21 | Gambro Lundia Ab | Polymeraffinitetsmatris, förfarande för framställning därav och anvädning därav |
EP1380290A1 (en) | 2002-07-09 | 2004-01-14 | Universitair Medisch Centrum Utrecht | Cross-beta structure pathway and its therapeutic relevance |
JP2007531537A (ja) | 2004-04-06 | 2007-11-08 | セダーズ−シナイ メディカル センター | アポリポタンパク質a−iおよびアポリポタンパク質a−imilanoをコードする組換えアデノ随伴ウイルスベクターによる血管疾患の予防および処置 |
US8114832B2 (en) | 2005-07-13 | 2012-02-14 | Crossbeta Biosciences B.V. | Method for detecting and/or removing a protein comprising a cross-beta structure from a pharmaceutical composition |
CA2615028A1 (en) | 2005-07-13 | 2007-01-18 | Crossbeta Biosciences B.V. | Cross-.beta. structure binding compounds |
CN101489655A (zh) | 2006-07-14 | 2009-07-22 | 威斯康星旧生研究基金会 | 捕获病毒用吸附膜 |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA939265A (en) * | 1967-11-18 | 1974-01-01 | Yoshitaka Ikezuki | Injectable compositions for alleviating the pain incurred from administrations of injections |
IT1127321B (it) * | 1979-12-28 | 1986-05-21 | Italfarmaco Spa | Composizione farmaceutiche aventi specifiche proprieta' terapeutiche nei confronti dell'edema polmonare acuto,di alcuni stati di shock e dell'iperfibrinolisi |
IT1127322B (it) * | 1979-12-28 | 1986-05-21 | Italfarmaco Spa | Composizioni farmaceutiche con esaltazione dell'attivita' terapeutica di cortisonici |
JPH01238534A (ja) * | 1988-03-17 | 1989-09-22 | Mitsui Toatsu Chem Inc | エンドトキシンの除去方法 |
US5019558A (en) * | 1988-05-09 | 1991-05-28 | Georges Cehovic | Method for treating memory disturbances using arginine aspartate |
GB8929076D0 (en) * | 1989-12-22 | 1990-02-28 | Scras | Treatment of shock by blocking agents of edrf effect or formation |
-
1991
- 1991-01-09 SE SE9100059A patent/SE468881B/sv not_active IP Right Cessation
- 1991-12-20 DK DK92903332.2T patent/DK0566644T3/da active
- 1991-12-20 ES ES92903332T patent/ES2109338T3/es not_active Expired - Lifetime
- 1991-12-20 DK DK96104316T patent/DK0719550T3/da active
- 1991-12-20 DE DE69223426T patent/DE69223426T2/de not_active Expired - Fee Related
- 1991-12-20 ES ES96104316T patent/ES2163543T3/es not_active Expired - Lifetime
- 1991-12-20 AT AT96104316T patent/ATE204753T1/de not_active IP Right Cessation
- 1991-12-20 JP JP50360692A patent/JP3200604B2/ja not_active Expired - Fee Related
- 1991-12-20 EP EP92903332A patent/EP0566644B1/en not_active Expired - Lifetime
- 1991-12-20 EP EP96104316A patent/EP0719550B1/en not_active Expired - Lifetime
- 1991-12-20 WO PCT/SE1991/000893 patent/WO1992011847A1/en active IP Right Grant
- 1991-12-20 AT AT92903332T patent/ATE157866T1/de not_active IP Right Cessation
- 1991-12-20 DE DE69132710T patent/DE69132710T2/de not_active Expired - Fee Related
- 1991-12-20 AU AU91528/91A patent/AU9152891A/en not_active Withdrawn
-
1992
- 1992-01-03 EP EP92850001A patent/EP0494848B1/en not_active Expired - Lifetime
- 1992-01-03 EP EP95118986A patent/EP0715849B1/en not_active Expired - Lifetime
- 1992-01-03 PT PT95118986T patent/PT715849E/pt unknown
-
1997
- 1997-12-02 GR GR970403223T patent/GR3025573T3/el unknown
Also Published As
Publication number | Publication date |
---|---|
EP0715849A1 (en) | 1996-06-12 |
AU9152891A (en) | 1992-08-17 |
EP0715849B1 (en) | 2001-07-25 |
EP0719550B1 (en) | 2001-08-29 |
EP0566644A1 (en) | 1993-10-27 |
DK0719550T3 (da) | 2001-12-10 |
SE9100059D0 (sv) | 1991-01-09 |
ES2163543T3 (es) | 2002-02-01 |
DE69223426D1 (de) | 1998-01-15 |
GR3025573T3 (en) | 1998-03-31 |
DE69132710T2 (de) | 2002-04-18 |
EP0494848B1 (en) | 1997-03-26 |
ATE157866T1 (de) | 1997-09-15 |
EP0719550A3 (es) | 1996-07-24 |
PT715849E (pt) | 2002-01-30 |
DE69132710D1 (de) | 2001-10-04 |
DE69223426T2 (de) | 1998-03-12 |
DK0566644T3 (da) | 1998-04-27 |
EP0494848A1 (en) | 1992-07-15 |
EP0566644B1 (en) | 1997-09-10 |
SE9100059L (sv) | 1992-07-10 |
EP0719550A2 (en) | 1996-07-03 |
SE468881B (sv) | 1993-04-05 |
JP3200604B2 (ja) | 2001-08-20 |
JPH06504058A (ja) | 1994-05-12 |
ATE204753T1 (de) | 2001-09-15 |
WO1992011847A1 (en) | 1992-07-23 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FG2A | Definitive protection |
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