MX173433B - Composicion acuosa de ibuprofen y procedimiento para su preparacion - Google Patents

Composicion acuosa de ibuprofen y procedimiento para su preparacion

Info

Publication number
MX173433B
MX173433B MX020055A MX2005590A MX173433B MX 173433 B MX173433 B MX 173433B MX 020055 A MX020055 A MX 020055A MX 2005590 A MX2005590 A MX 2005590A MX 173433 B MX173433 B MX 173433B
Authority
MX
Mexico
Prior art keywords
volume
percent
composition
weight percent
ibuprofen
Prior art date
Application number
MX020055A
Other languages
English (en)
Other versions
MX20055A (es
Inventor
Solomon Motola
Annabelle Mogavero
Gary R Agisim
Pamela N Panopoulos
Original Assignee
American Home Prod
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by American Home Prod filed Critical American Home Prod
Publication of MX20055A publication Critical patent/MX20055A/es
Publication of MX173433B publication Critical patent/MX173433B/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
    • A61K9/0095—Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)

Abstract

La presente invenciòn se refiere a procedimiento para la preparación de una composición de ibuprofen acuosa, de sabor neutro, apropiada para administración oral, que comprende aproximadamente 0,8 por ciento hasta aproximadamente 4 por ciento en peso de ibuprofen por volumen de la composición total en una combinación estabilizadora de suspensión primaria de ingredientes y una combinación primaria enmascaradora de sabor de ingredientes, caracterizado porque la combinación estabilizadora de suspensión de ingredientes comprende aproximadamente un0.1 por ciento hasta aproximadamente 2 por ciento en peso de combinación estabilizadora de suspensión por volumen de la composición total, comprendiendo la combinación enmascaradora de sabor aproximadamente un 20 por ciento hasta aproximadamente un 70 por ciento en peso de combinación enmascaradora de sabor por volumen de la composición total, conteniendo tambien la composición uno o más ácidos tamponadores farmaceuticamente aceptables y una cantidad suficiente para ajustar el pH entre aproximadamente 1,5 y hasta aproximadamente 3,5 y para proporcionar una capacidad tamponadora dentro de los límites de 0,03 a 0,05 entre el pH inicial y pH que es un 1,0 unidad de pH más elevado que el pH inicial, y agua en una cantidad suficiente para 100 por ciento en volumen de la composición.
MX020055A 1989-03-28 1990-03-27 Composicion acuosa de ibuprofen y procedimiento para su preparacion MX173433B (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/329,624 US4975465A (en) 1989-03-28 1989-03-28 Orally administrable ibuprofen compositions

Publications (2)

Publication Number Publication Date
MX20055A MX20055A (es) 1993-10-01
MX173433B true MX173433B (es) 1994-03-03

Family

ID=23286273

Family Applications (1)

Application Number Title Priority Date Filing Date
MX020055A MX173433B (es) 1989-03-28 1990-03-27 Composicion acuosa de ibuprofen y procedimiento para su preparacion

Country Status (15)

Country Link
US (1) US4975465A (es)
EP (1) EP0390369B1 (es)
JP (1) JP2847134B2 (es)
KR (1) KR0143899B1 (es)
AR (1) AR245366A1 (es)
AT (1) ATE100313T1 (es)
AU (1) AU629622B2 (es)
CA (1) CA1336819C (es)
DE (1) DE69006068T2 (es)
DK (1) DK0390369T3 (es)
ES (1) ES2048428T3 (es)
HK (1) HK68194A (es)
IE (1) IE64024B1 (es)
MX (1) MX173433B (es)
NZ (1) NZ233102A (es)

Families Citing this family (36)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5994041A (en) * 1985-04-06 1999-11-30 Eastman Kodak Company Process for buffering concentrated aqueous slurries
NZ234143A (en) * 1989-06-28 1991-10-25 Mcneil Ppc Inc Aqueous pharmaceutical suspension formulation for administering substantially insoluble pharmaceutical agents
US5262179A (en) * 1989-09-13 1993-11-16 Nicholas Kiwi Pty Ltd. Non-effervescent ibuprofen compositions
US5605930A (en) * 1991-10-21 1997-02-25 The United States Of America As Represented By The Department Of Health And Human Services Compositions and methods for treating and preventing pathologies including cancer
US5272137A (en) * 1992-02-14 1993-12-21 Mcneil-Pfc, Inc. Aqueous pharmaceutical suspension for pharmaceutical actives
AU2584092A (en) * 1992-09-03 1994-03-29 Affinity Biotech, Inc. Taste-masking pharmaceutical compositions and methods for making the same
CA2121435C (en) * 1993-04-16 2002-01-22 Sheila M. Ratnaraj Aqueous pharmaceutical suspension and process for preparation thereof
DE4327147C2 (de) * 1993-08-12 1996-12-19 Klinge Co Chem Pharm Fab Arzneimittelzusammensetzung, welche neben dem Wirkstoff ein Gemisch aus Gelatine unterschiedlicher Löslichkeit enthält
FR2713931B1 (fr) * 1993-12-20 1996-04-05 Laurence Paris Nouvelles compositions pharmaceutiques liquides à base d'ibuprofène et leur procédé de préparation.
US5609998A (en) * 1994-12-29 1997-03-11 Eastman Kodak Company Process for dispersing concentrated aqueous slurries
TW442287B (en) * 1995-06-13 2001-06-23 American Home Produits Corp Organoleptically acceptable oral pharmaceutical composition comprising the S(+)1,8-diethyl-1-1,3,4,9-tetrahydropyrano[3,4-b] indole-1-acetic acid (Etodolac)
CA2253260A1 (en) * 1996-05-02 1997-11-13 Taisho Pharmaceutical Co., Ltd. Suspension of sparingly water-soluble acidic drug
GB9625589D0 (en) 1996-12-10 1997-01-29 Boots Co Plc Therapeutic agents
DK1082109T3 (da) 1998-04-29 2004-08-09 Sumitomo Pharma Oral formulering omfattende biguanid og en organisk syre
GB0001315D0 (en) * 2000-01-20 2000-03-08 Novartis Ag Organic compounds
US20030039687A1 (en) * 2001-08-01 2003-02-27 Michael Corbo Taste masking composition
US20040132823A1 (en) * 2001-11-02 2004-07-08 Leo Pavliv Pharmaceutical composition of 2-(4-isobutylphenyl) propionic acid
ES2197781B1 (es) * 2001-12-04 2005-02-16 Farmalider, S.A. Composiciones farmaceuticas liquidas de base acuosa en forma de suspension para la administracion por via oral de ibuprofeno.
JP4619658B2 (ja) * 2002-03-12 2011-01-26 富山化学工業株式会社 快い味の経口懸濁液および方法
US7300670B2 (en) 2002-04-03 2007-11-27 Unilab Pharmatech, Ltd. Oral suspension formulation
CN101862292A (zh) * 2002-06-17 2010-10-20 塔罗制药美国公司 布洛芬混悬剂
KR100509432B1 (ko) * 2002-12-13 2005-08-22 주식회사 동구제약 Ｓ(+)-이부프로펜을 함유한 시럽제 조성물 및 그의 제조방법
FR2850275B1 (fr) 2003-01-24 2005-04-08 Scherer Technologies Inc R P Capsules molles a macher contenant une substance active a gout masque
ATE534371T1 (de) * 2003-02-06 2011-12-15 Gebro Pharma Gmbh Pharmazeutische zubereitungen und verfahren zu deren herstellung
US20040186180A1 (en) * 2003-03-21 2004-09-23 Gelotte Cathy K. Non-steroidal anti-inflammatory drug dosing regimen
CA2542755A1 (en) * 2003-10-17 2005-04-28 Medrx Co., Ltd. Biguanide drug-containing jelly preparation
GB2407497A (en) * 2003-10-30 2005-05-04 John Anthony Walters Method and formulation for the rapid and stable taste-masking of insoluble pharmaceutically active compounds using a surfactant and a hydrocolloid
US20050095300A1 (en) * 2003-10-30 2005-05-05 Wynn David W. Controlled release analgesic suspensions
US20050095299A1 (en) * 2003-10-30 2005-05-05 Wynn David W. Controlled release analgesic suspensions
US20050266031A1 (en) * 2004-05-25 2005-12-01 Jay Dickerson Pharmaceutical suspension composition
PL2486942T3 (pl) * 2004-11-24 2019-05-31 Meda Pharmaceuticals Inc Kompozycje zawierające azelastynę oraz sposoby ich stosowania
US8394415B2 (en) 2006-11-21 2013-03-12 Mcneil-Ppc, Inc Modified release analgesic suspensions
US9833510B2 (en) * 2007-06-12 2017-12-05 Johnson & Johnson Consumer Inc. Modified release solid or semi-solid dosage forms
US8362083B2 (en) * 2008-01-15 2013-01-29 C.B. Fleet Company Inc. Taste-masked docusate compositions
GB201006218D0 (en) * 2010-04-14 2010-06-02 Ayanda As Composition
AU2013235266B2 (en) 2012-03-20 2017-10-19 Particle Dynamics International, Llc Gelling agent-based dosage form

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4145440A (en) * 1977-08-18 1979-03-20 The Upjohn Company Liquid suspension of an aluminum salt of ibuprofen
US4361580A (en) * 1980-06-20 1982-11-30 The Upjohn Manufacturing Company Aluminum ibuprofen pharmaceutical suspensions
US4631580A (en) * 1984-11-09 1986-12-23 John Taube Video-stereoscopic-image-producing system
GB8609566D0 (en) * 1986-04-18 1986-05-21 Boots Co Plc Analgesic method
US4788220A (en) * 1987-07-08 1988-11-29 American Home Products Corporation (Del.) Pediatric ibuprofen compositions

Also Published As

Publication number Publication date
EP0390369A3 (en) 1991-05-15
ES2048428T3 (es) 1994-03-16
DK0390369T3 (da) 1994-04-11
AU629622B2 (en) 1992-10-08
CA1336819C (en) 1995-08-29
AU5226990A (en) 1990-10-04
AR245366A1 (es) 1994-01-31
NZ233102A (en) 1991-08-27
JPH02286615A (ja) 1990-11-26
IE901119L (en) 1990-09-28
IE64024B1 (en) 1995-06-28
EP0390369A2 (en) 1990-10-03
US4975465A (en) 1990-12-04
HK68194A (en) 1994-07-22
DE69006068D1 (de) 1994-03-03
KR0143899B1 (ko) 1998-07-15
EP0390369B1 (en) 1994-01-19
JP2847134B2 (ja) 1999-01-13
MX20055A (es) 1993-10-01
KR900013952A (ko) 1990-10-22
ATE100313T1 (de) 1994-02-15
DE69006068T2 (de) 1994-05-11

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