ES8707111A1 - Procedimiento para obtencion de un preparado farmaceutico para tratamiento terapeutico de enfermedades reumaticas. - Google Patents

Procedimiento para obtencion de un preparado farmaceutico para tratamiento terapeutico de enfermedades reumaticas.

Info

Publication number
ES8707111A1
ES8707111A1 ES538982A ES538982A ES8707111A1 ES 8707111 A1 ES8707111 A1 ES 8707111A1 ES 538982 A ES538982 A ES 538982A ES 538982 A ES538982 A ES 538982A ES 8707111 A1 ES8707111 A1 ES 8707111A1
Authority
ES
Spain
Prior art keywords
therapeutic treatment
pharmaceutical preparation
rheumatic diseases
radicals
antiphlogistically
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES538982A
Other languages
English (en)
Other versions
ES538982A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
A Natterman und Cie GmbH
Original Assignee
A Natterman und Cie GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by A Natterman und Cie GmbH filed Critical A Natterman und Cie GmbH
Publication of ES8707111A1 publication Critical patent/ES8707111A1/es
Publication of ES538982A0 publication Critical patent/ES538982A0/es
Expired legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/66—Phosphorus compounds
    • A61K31/683—Diesters of a phosphorus acid with two hydroxy compounds, e.g. phosphatidylinositols
    • A61K31/685—Diesters of a phosphorus acid with two hydroxy compounds, e.g. phosphatidylinositols one of the hydroxy compounds having nitrogen atoms, e.g. phosphatidylserine, lecithin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/06—Aluminium, calcium or magnesium; Compounds thereof, e.g. clay
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/02—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4808—Preparations in capsules, e.g. of gelatin, of chocolate characterised by the form of the capsule or the structure of the filling; Capsules containing small tablets; Capsules with outer layer for immediate drug release
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic System
    • C07F9/02—Phosphorus compounds
    • C07F9/06—Phosphorus compounds without P—C bonds
    • C07F9/08—Esters of oxyacids of phosphorus
    • C07F9/09—Esters of phosphoric acids
    • C07F9/10—Phosphatides, e.g. lecithin

Abstract

PROCEDIMIENTO PARA FABRICAR UN PREPARADO FARMACEUTICO. COMPRENDE: A) EMULSIONAR UN DERIVADO DE OXICAM DE FORMULA (I) Y UNA 1,2-DIAZIL-GLICERO-3-FOSFOCOLINA, EN METANOL O HEXANO; B) AGREGAR A LA EMULSION CLORURO CALCICO; C) CALENTAR LA EMULSION; D) SECAR POR PULVERIZACION LA EMULSION, PARA ELIMINAR EL DISOLVENTE Y OBTENER UN PRODUCTO SOLIDO; E) GRANULAR EL PRODUCTO SOLIDO; F) AÑADIR DE 0,1 A 2% EN PESO DE TOXOFERROLACETATO PARA ESTABILIZAR EL PRODUCTO SOLIDO; G) COMPRIMIR EN TABLETAS EL PRODUCTO ESTABILIZADO. SIENDO R1 UN ANILLO HETEROCICLICO; R2 Y R3 ANILLO AROMATICO CONDENSADO. SE UTILIZAN PARA COMBATIR LAS ENFERMEDADES REUMATICAS.
ES538982A 1983-12-22 1984-12-21 Procedimiento para obtencion de un preparado farmaceutico para tratamiento terapeutico de enfermedades reumaticas. Expired ES8707111A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE3346526A DE3346526C2 (de) 1983-12-22 1983-12-22 Pharmazeutisches Präparat zur therapeutischen Behandlung von rheumatischen Erkrankungen

Publications (2)

Publication Number Publication Date
ES8707111A1 true ES8707111A1 (es) 1987-07-16
ES538982A0 ES538982A0 (es) 1987-07-16

Family

ID=6217768

Family Applications (1)

Application Number Title Priority Date Filing Date
ES538982A Expired ES8707111A1 (es) 1983-12-22 1984-12-21 Procedimiento para obtencion de un preparado farmaceutico para tratamiento terapeutico de enfermedades reumaticas.

Country Status (24)

Country Link
US (1) US4687766A (es)
EP (1) EP0147735B1 (es)
JP (1) JPS60169420A (es)
KR (1) KR920003602B1 (es)
AT (1) ATE40793T1 (es)
AU (1) AU566974B2 (es)
CA (1) CA1234049A (es)
DD (1) DD233076A5 (es)
DE (2) DE3346526C2 (es)
DK (1) DK619484A (es)
EG (1) EG17137A (es)
ES (1) ES8707111A1 (es)
FI (1) FI83287C (es)
GR (1) GR82545B (es)
HU (1) HU193729B (es)
IL (1) IL73849A (es)
IN (1) IN162327B (es)
MX (1) MX159874A (es)
NO (1) NO166569C (es)
NZ (1) NZ210648A (es)
OA (1) OA07907A (es)
PH (1) PH21823A (es)
PT (1) PT79649B (es)
ZA (1) ZA849976B (es)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5154930A (en) * 1987-03-05 1992-10-13 The Liposome Company, Inc. Pharmacological agent-lipid solution preparation
US5376381A (en) * 1988-02-25 1994-12-27 The Liposome Company, Inc. Integrity protected gelatin
GB9212450D0 (en) * 1992-06-11 1992-07-22 Indena Spa New derivatives of non-steroidal anti-inflammatory,analgesic and/or antipyretic substances,their use and pharmaceutical formulations containing them
GB9325445D0 (en) 1993-12-13 1994-02-16 Cortecs Ltd Pharmaceutical formulations
US5763422A (en) * 1995-01-27 1998-06-09 Board Of Regents, The University Of Texas System Methods of enhancing the therapeutic activity of NSAIDS and compositions of zwitterionic phospholipids useful therein
US5955451A (en) * 1995-05-12 1999-09-21 The University Of Texas System Board Of Regents Methods of enhancing the therapeutic activity of NSAIDS and compositions of zwitterionic phospholipids useful therein
AUPN766496A0 (en) * 1996-01-22 1996-02-15 University Of New England, The Method and composition for the potentiation of anti-inflammatory drugs
NZ534142A (en) * 2002-01-21 2007-08-31 Vasogen Ireland Ltd Pharmaceutically acceptable phosphate-glycerol carrying bodies comprising phospatidylglycerol and/or phosphatidylcholine and/or phosphatidylglycerol
BR0215680A (pt) * 2002-04-26 2005-02-01 Rudolf Perl Composição farmacêutica oral estável
MXPA06000805A (es) * 2003-07-21 2006-04-18 Vasogen Ireland Ltd Liposomas que contienen grupos de glicerol fosfato para tratar una condicion inflamatoria aguda.

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3787324A (en) * 1971-03-01 1974-01-22 Warner Lambert Co 4-hydroxy-3-(3-isoxazolocarbamyl)-2h-1,2-benzothiazine 1,dioxides and process for their production
FR2343481A1 (fr) * 1976-03-11 1977-10-07 Gerlich Norbert Composition destinee a empecher les lesions des membranes biologiques et a regenerer ces membranes une fois qu'elles ont ete endommagees
AU518216B2 (en) * 1977-09-06 1981-09-17 Hafslund Nycomed Pharma Aktiengesellschaft Thienothiazine derivatives
JPS54117034A (en) * 1978-02-28 1979-09-11 Nippon Shoji Kk Treating agent for consciousness and perception motion disorder
DE2856333C2 (de) * 1978-12-27 1983-09-22 A. Nattermann & Cie GmbH, 5000 Köln Oral einnehmbare Arzneimittel mit entzündungshemmender Wirkung
DE2856339C2 (de) * 1978-12-27 1985-12-05 Fortuna-Werke Maschinenfabrik Gmbh, 7000 Stuttgart Vorrichtung zum kontinuierlichen, automatischen Zustellen von Setzstockbacken zur Halterung eines Werkstückes auf einer Rundschleifmaschine
DE2914788A1 (de) * 1979-04-11 1980-10-16 Nattermann A & Cie Parenteral applizierbare, stabile arzneimittelloesungen mit entzuendungshemmender wirkung
DE3047012A1 (de) * 1980-12-13 1982-07-22 A. Nattermann & Cie GmbH, 5000 Köln Verfahren zur abtrennung von acylierten phospholipiden aus diese enthaltenden phosphatidylcholin-produkten
DE3047011A1 (de) * 1980-12-13 1982-07-22 A. Nattermann & Cie GmbH, 5000 Köln Verfahren zur abtrennung von oel und/oder phosphatidylethanolamin aus diese enthaltenden alkoholloeslichen phosphatidylcholin-produkten
DE3047048A1 (de) * 1980-12-13 1982-07-29 A. Nattermann & Cie GmbH, 5000 Köln Verfahren zur abtrennung von oel und/oder phosphatidylethanolamin aus diese enthaltenden alkoholloeslichen phosphatidylcholin-produkten
US4434164A (en) * 1981-06-01 1984-02-28 Pfizer Inc. Crystalline benzothiazine dioxide salts
US4434163A (en) * 1981-06-01 1984-02-28 Pfizer Inc. Water-soluble benzothiazine dioxide salts
DE3217315C2 (de) * 1982-05-08 1986-05-22 Gödecke AG, 1000 Berlin Arzneimittelzubereitungen mit einem Gehalt an Oxicam-Derivaten

Also Published As

Publication number Publication date
DK619484D0 (da) 1984-12-21
IN162327B (es) 1988-04-30
MX159874A (es) 1989-09-25
NO166569C (no) 1991-08-14
NO844889L (no) 1985-06-24
AU566974B2 (en) 1987-11-05
US4687766A (en) 1987-08-18
ZA849976B (en) 1985-08-28
FI83287C (fi) 1991-06-25
PH21823A (en) 1988-03-04
JPH0112729B2 (es) 1989-03-02
NO166569B (no) 1991-05-06
DE3346526C2 (de) 1986-12-11
PT79649A (en) 1985-06-03
AU3668584A (en) 1985-06-27
FI845019A0 (fi) 1984-12-19
GR82545B (en) 1985-04-24
IL73849A0 (en) 1985-03-31
NZ210648A (en) 1988-04-29
FI845019L (fi) 1985-06-23
JPS60169420A (ja) 1985-09-02
ES538982A0 (es) 1987-07-16
KR920003602B1 (ko) 1992-05-04
IL73849A (en) 1988-07-31
FI83287B (fi) 1991-03-15
CA1234049A (en) 1988-03-15
DE3346526A1 (de) 1985-07-04
KR850004395A (ko) 1985-07-15
OA07907A (en) 1986-11-20
EP0147735B1 (de) 1989-02-15
DD233076A5 (de) 1986-02-19
EP0147735A2 (de) 1985-07-10
HUT35958A (en) 1985-08-28
PT79649B (en) 1986-10-21
DE3476734D1 (en) 1989-03-23
EG17137A (en) 1992-12-30
HU193729B (en) 1987-11-30
DK619484A (da) 1985-06-23
EP0147735A3 (en) 1985-11-27
ATE40793T1 (de) 1989-03-15

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Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 19970203