UY23373A1 - Procedimiento para preparar nuevas composiciones analgesicas - Google Patents

Procedimiento para preparar nuevas composiciones analgesicas

Info

Publication number
UY23373A1
UY23373A1 UY23373A UY23373A UY23373A1 UY 23373 A1 UY23373 A1 UY 23373A1 UY 23373 A UY23373 A UY 23373A UY 23373 A UY23373 A UY 23373A UY 23373 A1 UY23373 A1 UY 23373A1
Authority
UY
Uruguay
Prior art keywords
ibuprofen
procedure
composition
preparing new
analgesic compositions
Prior art date
Application number
UY23373A
Other languages
English (en)
Inventor
Shantilal Mody Dhiraj
George Blank Robert
Robert Agisim Gary
Yoshiko Chen Gloria
Original Assignee
American Home Prod
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by American Home Prod filed Critical American Home Prod
Publication of UY23373A1 publication Critical patent/UY23373A1/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/02—Halogenated hydrocarbons
    • A61K31/025—Halogenated hydrocarbons carbocyclic
    • A61K31/03—Halogenated hydrocarbons carbocyclic aromatic
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Dermatology (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pain & Pain Management (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Crystals, And After-Treatments Of Crystals (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)

Abstract

La invención proporciona procedimiento para la preparación de una composición analgésica tópica que comprende una emulsión de aceite en agua que contiene desde un 5% hasta un 12% en peso de ibuprofeno y un 60% hasta un 90% en peso de agua, consistiendo la fase oleosa de la emulsión esencialmente en constituyentes emolientes que no disuelven el ibuprofeno en grado importante a un pH de 4-7, teniendo la composición un pH de 4 hasta 7,2 de modo que el ibuprofeno esta suspendido en forma cristalina sustancialmente sólida y este disuelto esta parcialmente en el estado neutro o no carga do.
UY23373A 1991-02-11 1992-02-10 Procedimiento para preparar nuevas composiciones analgesicas UY23373A1 (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US65411791A 1991-02-11 1991-02-11
US74101191A 1991-08-06 1991-08-06
US07/814,995 US5210099A (en) 1991-02-11 1992-01-08 Analgesic compositions

Publications (1)

Publication Number Publication Date
UY23373A1 true UY23373A1 (es) 1992-07-23

Family

ID=27417914

Family Applications (1)

Application Number Title Priority Date Filing Date
UY23373A UY23373A1 (es) 1991-02-11 1992-02-10 Procedimiento para preparar nuevas composiciones analgesicas

Country Status (18)

Country Link
US (1) US5210099A (es)
EP (1) EP0499399B1 (es)
JP (1) JPH0558884A (es)
KR (1) KR920016087A (es)
AT (1) ATE147624T1 (es)
AU (1) AU650946B2 (es)
CA (1) CA2060833C (es)
DE (1) DE69216650T2 (es)
DK (1) DK0499399T3 (es)
ES (1) ES2096712T3 (es)
FI (1) FI100856B (es)
GR (1) GR3022886T3 (es)
IE (1) IE920245A1 (es)
MX (1) MX9200554A (es)
NO (1) NO179273C (es)
NZ (1) NZ241547A (es)
TW (1) TW225987B (es)
UY (1) UY23373A1 (es)

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DE4405641C2 (de) * 1994-02-22 1997-04-30 Roemmers Sa Pharmazeutische Zusammensetzung, enthaltend 2-(4-Methoxyphenoxy)-3-pyridinamin
US5654337A (en) * 1995-03-24 1997-08-05 II William Scott Snyder Topical formulation for local delivery of a pharmaceutically active agent
ES2118033B1 (es) * 1996-02-16 1999-07-01 Bial Ind Farmaceutica S A Formulacion farmaceutica antiinflamatoria.
US7629384B2 (en) * 1997-09-17 2009-12-08 Strategic Science & Technologies, Llc Topical delivery of L-arginine to cause beneficial effects
US7914814B2 (en) * 1997-09-17 2011-03-29 Strategic Science & Technologies, Llc Topical delivery of arginine of cause beneficial effects
US6083996A (en) * 1997-11-05 2000-07-04 Nexmed Holdings, Inc. Topical compositions for NSAI drug delivery
AU1800099A (en) * 1997-11-25 1999-06-15 Theratech, Inc. Transdermal delivery devices containing polydiorganosiloxane polymers to regulate adhesive properties
US6368618B1 (en) * 1999-07-01 2002-04-09 The University Of Georgia Research Foundation, Inc. Composition and method for enhanced transdermal absorption of nonsteroidal anti-inflammatory drugs
AU2002341984B2 (en) * 2001-10-04 2008-01-03 Macrochem Corporation Ibuprofen salt emulsifiers and cream formulations containing same
US20040132823A1 (en) * 2001-11-02 2004-07-08 Leo Pavliv Pharmaceutical composition of 2-(4-isobutylphenyl) propionic acid
EP1732577B1 (en) * 2004-02-23 2013-04-10 Strategic Science & Technologies, LLC Topical delivery of l-arginine to improve body and skin appearance
US20110028548A1 (en) * 2004-04-19 2011-02-03 Strategic Science & Technologies, Llc Beneficial effects of increasing local blood flow
ES2429443T3 (es) * 2004-04-19 2013-11-14 Strategic Science & Technologies, Llc Suministro transdérmico de sustancias beneficiosas efectuado mediante un entorno de fuerza iónica elevada
US20090105336A1 (en) * 2004-04-19 2009-04-23 Strategic Science & Technologies, Llc Beneficial Effects of Increasing Local Blood Flow
US9226909B2 (en) 2004-04-19 2016-01-05 Strategic Science & Technologies, Llc Beneficial effects of increasing local blood flow
JP4843494B2 (ja) * 2004-08-31 2011-12-21 Ｓｏファーマ株式会社 Ｓ／ｏ型外用剤
GB2423710A (en) * 2005-03-01 2006-09-06 Boots Healthcare Int Ltd Lozenge production process
US20070098660A1 (en) * 2005-10-27 2007-05-03 Jim Taneri Methods and compositions for epilation
US20080095831A1 (en) * 2006-08-10 2008-04-24 Mc Graw Thomas L Topical formulation of multilamellar vesicles composition for percutaneous absorption of pharmaceutically active agent
WO2009158144A1 (en) * 2008-05-30 2009-12-30 Fairfield Clinical Trials Llc Method and composition for dermatoses
BRPI0918142A2 (pt) 2008-09-10 2015-12-01 Biochemics Inc composição farmaclógica tópica, seu método de preparação, bem como uso da forma de ácido livre de ácido 2-(4-isobutifilfenil)prpiônico
WO2010034019A1 (en) 2008-09-22 2010-03-25 Biochemics, Inc. Transdermal drug delivery using an osmolyte and vasoactive agent
GB0818473D0 (en) 2008-10-08 2008-11-12 Probio Nutraceuticals As Composition
US20100099775A1 (en) * 2008-10-17 2010-04-22 Alpharx Inc. Method for ameliorating of post-anesthetic recovery
KR101643797B1 (ko) 2009-06-24 2016-07-28 스트러티직 사이언스 앤드 테크놀로지스, 엘엘씨 이부프로펜을 함유하는 국소 조성물
US9072659B2 (en) 2009-06-24 2015-07-07 Strategic Science & Technologies, Llc Topical composition containing naproxen
US11684624B2 (en) 2009-06-24 2023-06-27 Strategic Science & Technologies, Llc Treatment of erectile dysfunction and other indications
US9308213B2 (en) * 2010-10-29 2016-04-12 Infirst Healthcare Limited Solid solution compositions and use in chronic inflammation
US8895536B2 (en) 2010-10-29 2014-11-25 Infirst Healthcare Ltd. Compositions and methods for treating chronic inflammation and inflammatory diseases
US9271950B2 (en) 2010-10-29 2016-03-01 Infirst Healthcare Limited Compositions for treating chronic inflammation and inflammatory diseases
US11730709B2 (en) 2010-10-29 2023-08-22 Infirst Healthcare Limited Compositions and methods for treating severe pain
US11224659B2 (en) 2010-10-29 2022-01-18 Infirst Healthcare Limited Solid solution compositions and use in severe pain
US11202831B2 (en) 2010-10-29 2021-12-21 Infirst Healthcare Limited Solid solution compositions and use in cardiovascular disease
US9744132B2 (en) 2010-10-29 2017-08-29 Infirst Healthcare Limited Solid solution compositions and use in chronic inflammation
US9504664B2 (en) 2010-10-29 2016-11-29 Infirst Healthcare Limited Compositions and methods for treating severe pain
US10695432B2 (en) 2010-10-29 2020-06-30 Infirst Healthcare Limited Solid solution compositions and use in severe pain
US10695431B2 (en) 2010-10-29 2020-06-30 Infirst Healthcare Limited Solid solution compositions and use in cardiovascular disease
JP2014504592A (ja) 2010-12-29 2014-02-24 ストラテジック サイエンス アンド テクノロジーズ， エルエルシー 勃起不全および他の適応症の処置
JP2014501283A (ja) 2010-12-29 2014-01-20 ストラテジック サイエンス アンド テクノロジーズ， エルエルシー アレルギーおよび他の適応症の処置のためのシステムおよび方法
US9452135B2 (en) 2012-03-20 2016-09-27 Particle Dynamics International, Llc Gelling agent-based dosage form
JP6121796B2 (ja) * 2012-05-23 2017-04-26 キユーピー株式会社 脂肪乳剤および医薬品組成物中の非ステロイド性抗炎症薬の含有量を高める方法
US11007161B1 (en) 2014-12-31 2021-05-18 Eric Morrison Ibuprofen nanoparticle carriers encapsulated with hermatic surfactant films
US10596117B1 (en) 2014-12-31 2020-03-24 Eric Morrison Lipoleosomes as carriers for aromatic amide anesthetic compounds
US10561627B2 (en) 2014-12-31 2020-02-18 Eric Morrison Ibuprofen nanoparticle carriers encapsulated with hermetic surfactant films
US10500178B2 (en) 2015-03-13 2019-12-10 The Board Of Trustees Of The Leland Stanford Junior University LTB4 inhibition to prevent and treat human lymphedema
CA3082286A1 (en) 2017-12-04 2019-06-13 Johnson & Johnson Consumer Inc. Topical emulsion composition containing nonsteroidal anti-inflammatory drug

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US2742396A (en) * 1952-08-13 1956-04-17 Purdue Research Foundation Ointment base
CA727589A (en) * 1962-12-27 1966-02-08 Braun Ernest Depilatory composition
US4385049A (en) * 1981-05-12 1983-05-24 K-V Pharmaceutical Company Stable high internal phase ratio topical emulsions
JPS5829706A (ja) * 1981-08-14 1983-02-22 Toko Yakuhin Kogyo Kk 消炎鎮痛外用剤
JPS59139315A (ja) * 1983-01-31 1984-08-10 Taisho Pharmaceut Co Ltd クリ−ム剤
DE3532562A1 (de) * 1985-09-12 1987-03-12 Dolorgiet Gmbh & Co Kg Transdermal resorbierbare, wasserhaltige zubereitungen von arylpropionsaeurederivaten und verfahren zur herstellung derselben
US5093133A (en) * 1990-01-24 1992-03-03 Mcneil-Ppc, Inc. Method for percutaneous delivery of ibuprofen using hydroalcoholic gel

Also Published As

Publication number Publication date
FI920523A0 (fi) 1992-02-07
US5210099A (en) 1993-05-11
FI920523A (fi) 1992-08-12
AU1073092A (en) 1992-08-13
DE69216650T2 (de) 1997-05-07
JPH0558884A (ja) 1993-03-09
AU650946B2 (en) 1994-07-07
NO179273B (no) 1996-06-03
DE69216650D1 (de) 1997-02-27
NZ241547A (en) 1993-02-25
CA2060833A1 (en) 1992-08-12
MX9200554A (es) 1992-08-01
NO179273C (no) 1996-09-11
EP0499399A1 (en) 1992-08-19
IE920245A1 (en) 1992-08-12
ATE147624T1 (de) 1997-02-15
DK0499399T3 (da) 1997-02-03
CA2060833C (en) 1997-12-30
TW225987B (es) 1994-07-01
GR3022886T3 (en) 1997-06-30
NO920527L (no) 1992-08-12
FI100856B (fi) 1998-03-13
ES2096712T3 (es) 1997-03-16
NO920527D0 (no) 1992-02-10
KR920016087A (ko) 1992-09-24
EP0499399B1 (en) 1997-01-15

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Legal Events

Date Code Title Description
VENC Patent expired

Effective date: 20121230