ES2118033B1 - Formulacion farmaceutica antiinflamatoria. - Google Patents
Formulacion farmaceutica antiinflamatoria.Info
- Publication number
- ES2118033B1 ES2118033B1 ES9600374A ES9600374A ES2118033B1 ES 2118033 B1 ES2118033 B1 ES 2118033B1 ES 9600374 A ES9600374 A ES 9600374A ES 9600374 A ES9600374 A ES 9600374A ES 2118033 B1 ES2118033 B1 ES 2118033B1
- Authority
- ES
- Spain
- Prior art keywords
- weight
- pharmaceutically acceptable
- pharmaceutical formulation
- inflammatory
- nanoemulsion
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/192—Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/58—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
- A61K9/1075—Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Epidemiology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Molecular Biology (AREA)
- Dispersion Chemistry (AREA)
- Biophysics (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
FORMULACION FARMACEUTICA ANTIINFLAMATORIA. FORMULACION FARMACEUTICA QUE CONTIENE UN EUTOMERO DE AL MENOS UN PRINCIPIO ACTIVO ANTIINFLAMATORIO, QUIRAL E HIDROINSOLUBLE, CON UN PH FISIOLOGICAMENTE ACEPTABLE, EN FORMA DE NANOEMULSION. LA NANOEMULSION CONTIENE 3 A 50% EN PESO DE UN SOLVENTE ORGANICO FARMACEUTICAMENTE ACEPTABLE, NO MISCIBLE EN AGUA, DE CARACTER APOLAR Y NO-IONICO QUE CONSTITUYE LA FASE INTERNA DE LA NANOEMULSION; 5 A 45% EN PESO DE UN AGENTE SURFACTANTE NO-IONICO FARMACEUTICAMENTE ACEPTABLE; 5 A 30% EN PESO DE UN AGENTE CO-SURFACTANTE NO-IONICO FARMACEUTICAMENTE ACEPTABLE; 5 A 87% EN PESO DE AGUA O DE UNA SOLUCION TAMPON FARMACEUTICAMENTE ACEPTABLE; COMO INGREDIENTE ACTIVO, 0,1 A 1,0% EN PESO DE UN EUTOMERO DE AL MENOS UN PRINCIPIO ANTIINFLAMATORIO, QUIRAL E HIDROINSOLUBLE; 0 A 6,5% DE AL MENOS UN EXCIPIENTE COMPLEMENTARIO FARMACEUTICAMENTE ACEPTABLE. EL INGREDIENTE ACTIVO ESTA VEHICULADO EN DISOLUCION MOLECULAR EN EL SOLVENTE ORGANICO.
Priority Applications (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ES9600374A ES2118033B1 (es) | 1996-02-16 | 1996-02-16 | Formulacion farmaceutica antiinflamatoria. |
| PCT/ES1997/000238 WO1999016424A1 (es) | 1996-02-16 | 1997-09-30 | Formulacion farmaceutica antiinflamatoria |
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ES9600374A ES2118033B1 (es) | 1996-02-16 | 1996-02-16 | Formulacion farmaceutica antiinflamatoria. |
| PCT/ES1997/000238 WO1999016424A1 (es) | 1996-02-16 | 1997-09-30 | Formulacion farmaceutica antiinflamatoria |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| ES2118033A1 ES2118033A1 (es) | 1998-09-01 |
| ES2118033B1 true ES2118033B1 (es) | 1999-07-01 |
Family
ID=26154947
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES9600374A Expired - Fee Related ES2118033B1 (es) | 1996-02-16 | 1996-02-16 | Formulacion farmaceutica antiinflamatoria. |
Country Status (2)
| Country | Link |
|---|---|
| ES (1) | ES2118033B1 (es) |
| WO (1) | WO1999016424A1 (es) |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SE8004580L (sv) * | 1980-06-19 | 1981-12-20 | Draco Ab | Farmaceutisk beredning |
| GB8630273D0 (en) * | 1986-12-18 | 1987-01-28 | Til Medical Ltd | Pharmaceutical delivery systems |
| US5104656A (en) * | 1989-06-16 | 1992-04-14 | Seth Pyare L | Percutaneous treatment with a high potency non-steroidal anti-inflammatory agent |
| US5210099A (en) * | 1991-02-11 | 1993-05-11 | American Home Products Corporation | Analgesic compositions |
| EP0656779B1 (en) * | 1992-08-28 | 2000-04-12 | Pharmos Corporation | Submicron emulsions as ocular drug delivery vehicles |
| US5576016A (en) * | 1993-05-18 | 1996-11-19 | Pharmos Corporation | Solid fat nanoemulsions as drug delivery vehicles |
| GB9409778D0 (en) * | 1994-05-16 | 1994-07-06 | Dumex Ltd As | Compositions |
| ES2094688B1 (es) * | 1994-08-08 | 1997-08-01 | Cusi Lab | Manoemulsion del tipo de aceite en agua, util como vehiculo oftalmico y procedimiento para su preparacion. |
-
1996
- 1996-02-16 ES ES9600374A patent/ES2118033B1/es not_active Expired - Fee Related
-
1997
- 1997-09-30 WO PCT/ES1997/000238 patent/WO1999016424A1/es active Application Filing
Also Published As
| Publication number | Publication date |
|---|---|
| WO1999016424A1 (es) | 1999-04-08 |
| ES2118033A1 (es) | 1998-09-01 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| EC2A | Search report published |
Date of ref document: 19980901 Kind code of ref document: A1 Effective date: 19980901 |
|
| PC2A | Transfer of patent | ||
| FA2A | Application withdrawn |
Effective date: 20001108 |
|
| FD2A | Announcement of lapse in spain |
Effective date: 20180807 |