HK1185887A1 - 改良的抗體分子 - Google Patents

改良的抗體分子

Info

Publication number
HK1185887A1
HK1185887A1 HK13113190.6A HK13113190A HK1185887A1 HK 1185887 A1 HK1185887 A1 HK 1185887A1 HK 13113190 A HK13113190 A HK 13113190A HK 1185887 A1 HK1185887 A1 HK 1185887A1
Authority
HK
Hong Kong
Prior art keywords
antibody molecules
improved antibody
improved
molecules
antibody
Prior art date
Application number
HK13113190.6A
Other languages
English (en)
Inventor
井川智之
石井慎也
前田敦彥
櫻井實香
小島哲郎
橘達彥
白岩宙丈
角田浩行
樋口義信
Original Assignee
中外制藥株式會社
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=42059767&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=HK1185887(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by 中外制藥株式會社 filed Critical 中外制藥株式會社
Publication of HK1185887A1 publication Critical patent/HK1185887A1/zh

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2866—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for cytokines, lymphokines, interferons
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A—HUMAN NECESSITIES
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    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
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    • A61P9/14—Vasoprotectives; Antihaemorrhoidals; Drugs for varicose therapy; Capillary stabilisers
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/46—Hybrid immunoglobulins
    • C07K16/461—Igs containing Ig-regions, -domains or -residues form different species
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/40—Immunoglobulins specific features characterized by post-translational modification
    • C07K2317/41—Glycosylation, sialylation, or fucosylation
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
    • C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value
HK13113190.6A 2008-09-26 2013-11-26 改良的抗體分子 HK1185887A1 (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP2008248213 2008-09-26
JP2009060806 2009-03-13
JP2009067925 2009-03-19

Publications (1)

Publication Number Publication Date
HK1185887A1 true HK1185887A1 (zh) 2014-02-28

Family

ID=42059767

Family Applications (2)

Application Number Title Priority Date Filing Date
HK11101085.1A HK1147107A1 (en) 2008-09-26 2011-02-01 Improved antibody molecules
HK13113190.6A HK1185887A1 (zh) 2008-09-26 2013-11-26 改良的抗體分子

Family Applications Before (1)

Application Number Title Priority Date Filing Date
HK11101085.1A HK1147107A1 (en) 2008-09-26 2011-02-01 Improved antibody molecules

Country Status (35)

Country Link
US (8) US8562991B2 (zh)
EP (1) EP2330193B1 (zh)
JP (2) JP4550938B2 (zh)
KR (2) KR101690334B1 (zh)
CN (2) CN103254310B (zh)
AR (2) AR073404A1 (zh)
AU (1) AU2009290162B2 (zh)
BR (1) BRPI0905076B8 (zh)
CA (2) CA2763039C (zh)
CL (1) CL2011000632A1 (zh)
CO (1) CO6362048A2 (zh)
CR (1) CR20110204A (zh)
DK (1) DK2330193T3 (zh)
EC (1) ECSP11011003A (zh)
ES (1) ES2546800T3 (zh)
FI (1) FIC20210049I1 (zh)
FR (1) FR21C1054I2 (zh)
HK (2) HK1147107A1 (zh)
HR (1) HRP20150857T1 (zh)
HU (2) HUE027533T2 (zh)
IL (1) IL211850A0 (zh)
LT (1) LTC2330193I2 (zh)
MA (1) MA32707B1 (zh)
MX (1) MX2010003256A (zh)
MY (1) MY153908A (zh)
NL (1) NL301152I2 (zh)
NZ (1) NZ592214A (zh)
PE (1) PE20120079A1 (zh)
PL (1) PL2330193T3 (zh)
PT (1) PT2330193E (zh)
RU (1) RU2430111C3 (zh)
SI (1) SI2330193T1 (zh)
TW (1) TWI440469B (zh)
WO (1) WO2010035769A1 (zh)
ZA (1) ZA201103027B (zh)

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JP5144499B2 (ja) 2006-03-31 2013-02-13 中外製薬株式会社 二重特異性抗体を精製するための抗体改変方法
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CA2648644C (en) 2006-04-07 2016-01-05 Osaka University Muscle regeneration promoter
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KR102269708B1 (ko) 2008-04-11 2021-06-25 추가이 세이야쿠 가부시키가이샤 복수 분자의 항원에 반복 결합하는 항원 결합 분자
TWI528973B (zh) 2008-06-05 2016-04-11 Chugai Pharmaceutical Co Ltd Nerve infiltration inhibitor
TWI440469B (zh) 2008-09-26 2014-06-11 Chugai Pharmaceutical Co Ltd Improved antibody molecules
JO3672B1 (ar) 2008-12-15 2020-08-27 Regeneron Pharma أجسام مضادة بشرية عالية التفاعل الكيماوي بالنسبة لإنزيم سبتيليسين كنفرتيز بروبروتين / كيكسين نوع 9 (pcsk9).
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RU2524152C2 (ru) * 2009-03-19 2014-07-27 Чугаи Сейяку Кабусики Кайся Средство для лечения ревматоидного артрита
TWI646193B (zh) 2009-03-19 2019-01-01 中外製藥股份有限公司 抗體恆定區域改變體
KR101436219B1 (ko) 2009-10-26 2014-09-01 에프. 호프만-라 로슈 아게 글리코실화된 면역글로불린의 제조 방법
JO3417B1 (ar) 2010-01-08 2019-10-20 Regeneron Pharma الصيغ المستقرة التي تحتوي على الأجسام المضادة لمضاد مستقبل( interleukin-6 (il-6r
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US20240010738A1 (en) 2024-01-11
CN103254310B (zh) 2015-08-12
HK1147107A1 (en) 2011-07-29
DK2330193T3 (en) 2015-08-24
US8562991B2 (en) 2013-10-22
FIC20210049I1 (fi) 2021-12-13
ES2546800T3 (es) 2015-09-29
KR20110046385A (ko) 2011-05-04
HRP20150857T1 (hr) 2015-10-09
CL2011000632A1 (es) 2011-06-03
CR20110204A (es) 2011-06-03
BRPI0905076B1 (pt) 2021-01-05
PL2330193T3 (pl) 2015-11-30
KR20100061834A (ko) 2010-06-09
NL301152I2 (nl) 2022-01-13
SI2330193T1 (sl) 2015-10-30
MX2010003256A (es) 2010-08-04
RU2430111C3 (ru) 2022-03-31
US10662245B2 (en) 2020-05-26
LTPA2021013I1 (zh) 2021-12-10
CA2699834C (en) 2012-03-13
IL211850A0 (en) 2011-06-30
JP5661291B2 (ja) 2015-01-28
US20110098450A1 (en) 2011-04-28
CN101849006A (zh) 2010-09-29
AU2009290162B2 (en) 2011-11-10
LTC2330193I2 (zh) 2022-10-10
JP2010239958A (ja) 2010-10-28
WO2010035769A1 (ja) 2010-04-01
AR127010A2 (es) 2023-12-06
TWI440469B (zh) 2014-06-11
MY153908A (en) 2015-04-15
EP2330193A1 (en) 2011-06-08
KR101044180B1 (ko) 2011-06-24
US20200231688A1 (en) 2020-07-23
CN103254310A (zh) 2013-08-21
JPWO2010035769A1 (ja) 2012-02-23
US20230159648A1 (en) 2023-05-25
BRPI0905076A2 (pt) 2015-07-07
ECSP11011003A (es) 2011-05-31
NL301152I1 (zh) 2021-12-15
RU2430111C1 (ru) 2011-09-27
NZ592214A (en) 2012-09-28
US20220306755A1 (en) 2022-09-29
US20120253016A1 (en) 2012-10-04

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