ES504257A0 - Procedimiento para la obtencion de derivados de imidazol trisustituidos - Google Patents

Procedimiento para la obtencion de derivados de imidazol trisustituidos

Info

Publication number
ES504257A0
ES504257A0 ES504257A ES504257A ES504257A0 ES 504257 A0 ES504257 A0 ES 504257A0 ES 504257 A ES504257 A ES 504257A ES 504257 A ES504257 A ES 504257A ES 504257 A0 ES504257 A0 ES 504257A0
Authority
ES
Spain
Prior art keywords
trisustituted
procedure
obtaining
imidazole derivatives
imidazole
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
ES504257A
Other languages
English (en)
Spanish (es)
Other versions
ES8301472A1 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novartis AG
Original Assignee
Ciba Geigy AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ciba Geigy AG filed Critical Ciba Geigy AG
Publication of ES8301472A1 publication Critical patent/ES8301472A1/es
Publication of ES504257A0 publication Critical patent/ES504257A0/es
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/04—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/44—Radicals substituted by doubly-bound oxygen, sulfur, or nitrogen atoms, or by two such atoms singly-bound to the same carbon atom
    • C07D213/53—Nitrogen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/44—Radicals substituted by doubly-bound oxygen, sulfur, or nitrogen atoms, or by two such atoms singly-bound to the same carbon atom
    • C07D213/46—Oxygen atoms
    • C07D213/50—Ketonic radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/04—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D233/20—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C07D233/26—Radicals substituted by carbon atoms having three bonds to hetero atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/64—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms, e.g. histidine

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Virology (AREA)
  • Communicable Diseases (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Oncology (AREA)
  • Dermatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Cosmetics (AREA)
ES504257A 1980-07-25 1981-07-24 Procedimiento para la obtencion de derivados de imidazol trisustituidos Granted ES504257A0 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH571580 1980-07-25

Publications (2)

Publication Number Publication Date
ES8301472A1 ES8301472A1 (es) 1982-12-01
ES504257A0 true ES504257A0 (es) 1982-12-01

Family

ID=4298165

Family Applications (8)

Application Number Title Priority Date Filing Date
ES504257A Granted ES504257A0 (es) 1980-07-25 1981-07-24 Procedimiento para la obtencion de derivados de imidazol trisustituidos
ES514585A Expired ES8307245A1 (es) 1980-07-25 1982-07-30 Procedimiento para la obtencion de derivados de oxazol trisustituidos.
ES514582A Expired ES8306122A1 (es) 1980-07-25 1982-07-30 Procedimiento para la obtencion de derivados de imidazol trisustituidos.
ES514580A Granted ES514580A0 (es) 1980-07-25 1982-07-30 Procedimiento para la obtencion de derivados de imidazol trisustituidos.
ES514583A Granted ES514583A0 (es) 1980-07-25 1982-07-30 Procedimiento para la obtencion de derivados de imidazol trisustituidos.
ES514584A Expired ES8306124A1 (es) 1980-07-25 1982-07-30 Procedimiento para la obtencion de derivados de imidazol trisustituidos.
ES514581A Granted ES514581A0 (es) 1980-07-25 1982-07-30 Procedimiento para la obtencion de derivados de imidazol trisustituidos.
ES514579A Expired ES8306119A1 (es) 1980-07-25 1982-07-30 Procedimiento para la obtencion de derivados de imidazol trisustituidos.

Family Applications After (7)

Application Number Title Priority Date Filing Date
ES514585A Expired ES8307245A1 (es) 1980-07-25 1982-07-30 Procedimiento para la obtencion de derivados de oxazol trisustituidos.
ES514582A Expired ES8306122A1 (es) 1980-07-25 1982-07-30 Procedimiento para la obtencion de derivados de imidazol trisustituidos.
ES514580A Granted ES514580A0 (es) 1980-07-25 1982-07-30 Procedimiento para la obtencion de derivados de imidazol trisustituidos.
ES514583A Granted ES514583A0 (es) 1980-07-25 1982-07-30 Procedimiento para la obtencion de derivados de imidazol trisustituidos.
ES514584A Expired ES8306124A1 (es) 1980-07-25 1982-07-30 Procedimiento para la obtencion de derivados de imidazol trisustituidos.
ES514581A Granted ES514581A0 (es) 1980-07-25 1982-07-30 Procedimiento para la obtencion de derivados de imidazol trisustituidos.
ES514579A Expired ES8306119A1 (es) 1980-07-25 1982-07-30 Procedimiento para la obtencion de derivados de imidazol trisustituidos.

Country Status (23)

Country Link
US (1) US4447431A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
EP (1) EP0045081B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
JP (1) JPS5756466A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
KR (13) KR850000883B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
AR (1) AR230269A1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
AT (1) ATE17349T1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
AU (2) AU7340481A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
CA (1) CA1175431A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
DD (2) DD201677A5 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
DE (1) DE3173434D1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
DK (1) DK331881A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
ES (8) ES504257A0 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
FI (1) FI812326L (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
GB (1) GB2080805B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
GR (1) GR75287B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
IE (1) IE52071B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
IL (1) IL63410A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
NO (1) NO812542L (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
NZ (1) NZ197828A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
PL (8) PL237005A1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
PT (1) PT73424B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
SU (8) SU1235454A3 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)
ZA (1) ZA815078B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html)

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WO1983002613A1 (en) * 1981-07-20 1983-08-04 Sallmann, Alfred Trisubstituted oxazo compounds
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FR2633291B1 (fr) * 1988-06-27 1990-09-07 Oreal Derives d'hydroxy-4 isoxazoles, leur procede de preparation et compositions cosmetiques et pharmaceutiques les contenant
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US5916891A (en) 1992-01-13 1999-06-29 Smithkline Beecham Corporation Pyrimidinyl imidazoles
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US5593992A (en) * 1993-07-16 1997-01-14 Smithkline Beecham Corporation Compounds
US5593991A (en) * 1993-07-16 1997-01-14 Adams; Jerry L. Imidazole compounds, use and process of making
US5670527A (en) * 1993-07-16 1997-09-23 Smithkline Beecham Corporation Pyridyl imidazole compounds and compositions
DE69433501T2 (de) * 1993-11-08 2004-11-04 Smithkline Beecham Corp. Oxazole zur behandlung von zytokinvermittelten erkrankungen
US5723477A (en) * 1994-11-10 1998-03-03 Sibia Neurosciences, Inc. Modulators of acetylcholine receptors
US6369068B1 (en) 1995-06-07 2002-04-09 Smithkline Beecham Corporation Amino substituted pyrimidine containing compounds
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US5739143A (en) * 1995-06-07 1998-04-14 Smithkline Beecham Corporation Imidazole compounds and compositions
ZA9610687B (en) * 1995-12-22 1997-09-29 Smithkline Beecham Corp Novel synthesis.
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US6046208A (en) * 1996-01-11 2000-04-04 Smithkline Beecham Corporation Substituted imidazole compounds
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US5929076A (en) * 1997-01-10 1999-07-27 Smithkline Beecham Corporation Cycloalkyl substituted imidazoles
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JP2002504909A (ja) 1997-06-13 2002-02-12 スミスクライン・ビーチャム・コーポレイション 新規な置換ピラゾールおよびピラゾリン化合物
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US6489325B1 (en) 1998-07-01 2002-12-03 Smithkline Beecham Corporation Substituted imidazole compounds
US6251914B1 (en) 1997-07-02 2001-06-26 Smithkline Beecham Corporation Cycloalkyl substituted imidazoles
TW517055B (en) 1997-07-02 2003-01-11 Smithkline Beecham Corp Novel substituted imidazole compounds
US6562832B1 (en) 1997-07-02 2003-05-13 Smithkline Beecham Corporation Substituted imidazole compounds
AR016294A1 (es) * 1997-07-02 2001-07-04 Smithkline Beecham Corp Compuesto de imidazol sustituido, composicion farmaceutica que la contiene, su uso en la fabricacion de un medicamento y procedimiento para supreparacion
US7301021B2 (en) * 1997-07-02 2007-11-27 Smithkline Beecham Corporation Substituted imidazole compounds
CA2306077A1 (en) 1997-10-08 1999-04-15 Smithkline Beecham Corporation Novel cycloalkenyl substituted compounds
JP2001526230A (ja) 1997-12-19 2001-12-18 スミスクライン・ビーチャム・コーポレイション ヘテロアリール置換イミダゾール化合物、その医薬組成物および使用
CZ20004339A3 (cs) 1998-05-22 2001-10-17 Smithkline Beecham Corporation Nové 2-alkylem substituované imidazolové sloučeniny
US6858617B2 (en) 1998-05-26 2005-02-22 Smithkline Beecham Corporation Substituted imidazole compounds
ATE266399T1 (de) * 1998-08-20 2004-05-15 Smithkline Beecham Corp Neue substituierte triazolverbindungen
US6548503B1 (en) 1998-11-04 2003-04-15 Smithkline Beecham Corporation Pyridin-4-yl or pyrimidin-4-yl substituted pyrazines
WO2000029399A1 (en) * 1998-11-12 2000-05-25 Boehringer Ingelheim (Canada) Ltd. Antiherpes compounds
US6239279B1 (en) 1998-12-16 2001-05-29 Smithkline Beecham Corporation Synthesis for 4-aryl-5-pyrimidine imidazole substituted derivatives
PL355912A1 (en) 1999-11-22 2004-05-31 Smithkline Beecham Plc. Novel compounds
EP1233951B1 (en) 1999-11-23 2005-06-01 SmithKline Beecham Corporation 3,4-dihydro-(1h)quinazolin-2-one compounds as csbp/p38 kinase inhibitors
ES2249309T3 (es) 1999-11-23 2006-04-01 Smithkline Beecham Corp Compuestos de 3,4-dihidro-(1h)quinazolin-2-ona como inhibidores de csbp/p39 kinasa.
EP1235814B1 (en) 1999-11-23 2004-11-03 Smithkline Beecham Corporation 3,4-DIHYDRO-(1H)QUINAZOLIN-2-ONE COMPOUNDS AS CSBP/p38 KINASE INHIBITORS
US6759410B1 (en) * 1999-11-23 2004-07-06 Smithline Beecham Corporation 3,4-dihydro-(1H)-quinazolin-2-ones and their use as CSBP/p38 kinase inhibitors
US7235551B2 (en) * 2000-03-02 2007-06-26 Smithkline Beecham Corporation 1,5-disubstituted-3,4-dihydro-1h-pyrimido[4,5-d]pyrimidin-2-one compounds and their use in treating csbp/p38 kinase mediated diseases
GB0005357D0 (en) 2000-03-06 2000-04-26 Smithkline Beecham Plc Compounds
ATE266022T1 (de) * 2000-03-06 2004-05-15 Smithkline Beecham Plc Imidazol derivate als raf kinase inhibitoren
WO2002059083A2 (en) * 2000-10-23 2002-08-01 Smithkline Beecham Corporation Novel compounds
GB0112348D0 (en) * 2001-05-19 2001-07-11 Smithkline Beecham Plc Compounds
WO2003022837A1 (en) * 2001-09-05 2003-03-20 Smithkline Beecham P.L.C. Heterocycle-carboxamide derivatives as raf kinase inhibitors
CA2468783A1 (en) * 2001-12-18 2003-06-26 F. Hoffmann-La Roche Ag Cis-imidazolines as mdm2 inhibitors
TW200505446A (en) * 2003-01-17 2005-02-16 Fuj Isawa Pharmaceutical Co Ltd Inhibitor of cox
EP1620406A2 (en) * 2003-05-08 2006-02-01 Astellas Pharma Inc. 1,2-diarylimidazoles useful as inhibitors of cox
MY145343A (en) 2005-03-25 2012-01-31 Glaxo Group Ltd Novel compounds
JP2008537937A (ja) * 2005-03-25 2008-10-02 グラクソ グループ リミテッド ピリド［２，３−ｄ］ピリミジン−７−オンおよび３，４−ジヒドロピリミド［４，５−ｄ］ピリミジン−２（１Ｈ）−オン誘導体の製造方法
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US4372964A (en) * 1980-10-30 1983-02-08 E. I. Du Pont De Nemours And Company Antiinflammatory 4,5-diaryl-1H-imidazole-2-methanols

Also Published As

Publication number Publication date
ES8301472A1 (es) 1982-12-01
PT73424B (en) 1983-06-20
IL63410A (en) 1986-04-29
KR850002746A (ko) 1985-05-15
KR850002745A (ko) 1985-05-15
KR850002750A (ko) 1985-05-15
KR850000911B1 (ko) 1985-06-27
KR850002747A (ko) 1985-05-15
KR850002754A (ko) 1985-05-15
ES8306120A1 (es) 1983-05-16
PL237003A1 (en) 1983-02-28
PL237004A1 (en) 1983-02-28
EP0045081A3 (en) 1982-04-07
ES8306123A1 (es) 1983-05-16
PL237000A1 (en) 1983-02-28
IL63410A0 (en) 1981-10-30
SU1138023A3 (ru) 1985-01-30
KR850000883B1 (ko) 1985-06-26
DD201677A5 (de) 1983-08-03
ZA815078B (en) 1982-07-28
ES514580A0 (es) 1983-05-16
AU7340481A (en) 1982-01-28
SU1205764A3 (ru) 1986-01-15
ES514582A0 (es) 1983-05-16
KR850002756A (ko) 1985-05-15
KR850002752A (ko) 1985-05-15
SU1205763A3 (ru) 1986-01-15
ES514579A0 (es) 1983-05-16
NO812542L (no) 1982-01-26
US4447431A (en) 1984-05-08
KR850002753A (ko) 1985-05-15
ES514585A0 (es) 1983-07-01
SU1145928A3 (ru) 1985-03-15
SU1227112A3 (ru) 1986-04-23
ES514584A0 (es) 1983-05-16
FI812326A7 (fi) 1982-01-26
KR850000884B1 (ko) 1985-06-26
DK331881A (da) 1982-01-26
KR850000889B1 (ko) 1985-06-26
PL232352A1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1982-12-20
JPS5756466A (en) 1982-04-05
NZ197828A (en) 1985-11-08
SU1235454A3 (ru) 1986-05-30
ES8306119A1 (es) 1983-05-16
KR850002744A (ko) 1985-05-15
AU5655586A (en) 1986-09-11
KR850000888B1 (ko) 1985-06-26
IE52071B1 (en) 1987-06-10
KR850000891B1 (ko) 1985-06-26
GR75287B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) 1984-07-13
KR850002755A (ko) 1985-05-15
KR850000885B1 (ko) 1985-06-26
ES8307245A1 (es) 1983-07-01
ES8306121A1 (es) 1983-05-16
EP0045081B1 (de) 1986-01-08
KR850000886B1 (ko) 1985-06-26
ES8306122A1 (es) 1983-05-16
EP0045081A2 (de) 1982-02-03
AR230269A1 (es) 1984-03-01
ATE17349T1 (de) 1986-01-15
PL237001A1 (en) 1983-02-28
KR850000873B1 (ko) 1985-06-22
KR850001064B1 (ko) 1985-07-25
KR850002749A (ko) 1985-05-15
DE3173434D1 (en) 1986-02-20
ES514583A0 (es) 1983-05-16
PL135822B1 (en) 1985-12-31
IE811680L (en) 1982-01-25
SU1169534A3 (ru) 1985-07-23
KR830006230A (ko) 1983-09-20
FI812326L (fi) 1982-01-26
ES514581A0 (es) 1983-05-16
ES8306124A1 (es) 1983-05-16
KR850000892B1 (ko) 1985-06-26
SU1152520A3 (en) 1985-04-23
DD202554A5 (de) 1983-09-21
PL237002A1 (en) 1983-02-28
KR850002748A (ko) 1985-05-15
PL236997A1 (en) 1983-01-03
PT73424A (en) 1981-08-01
CA1175431A (en) 1984-10-02
PL237005A1 (en) 1983-02-28
GB2080805B (en) 1984-03-07
GB2080805A (en) 1982-02-10
KR850000890B1 (ko) 1985-06-26
KR850000887B1 (ko) 1985-06-26

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