ES2536465T3 - Composición de péptidos tumor-asociados y relacionados con la vacuna contra el cáncer para el tratamiento de glioblastoma (GBM) y otros cánceres - Google Patents

Composición de péptidos tumor-asociados y relacionados con la vacuna contra el cáncer para el tratamiento de glioblastoma (GBM) y otros cánceres Download PDF

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Publication number
ES2536465T3
ES2536465T3 ES08017305.7T ES08017305T ES2536465T3 ES 2536465 T3 ES2536465 T3 ES 2536465T3 ES 08017305 T ES08017305 T ES 08017305T ES 2536465 T3 ES2536465 T3 ES 2536465T3
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Prior art keywords
cancer
peptide
tumor
peptides
expression
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English (en)
Spanish (es)
Inventor
Oliver Schoor
Norbert Hilf
Toni Weinschenk
Claudia Trautwein
Steffen Walter
Harpreet Singh
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Immatics Biotechnologies GmbH
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Immatics Biotechnologies GmbH
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/08—Peptides having 5 to 11 amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/14—Blood; Artificial blood
    • A61K35/17—Lymphocytes; B-cells; T-cells; Natural killer cells; Interferon-activated or cytokine-activated lymphocytes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K40/10—Cellular immunotherapy characterised by the cell type used
    • A61K40/11—T-cells, e.g. tumour infiltrating lymphocytes [TIL] or regulatory T [Treg] cells; Lymphokine-activated killer [LAK] cells
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    • A61K40/20—Cellular immunotherapy characterised by the effect or the function of the cells
    • A61K40/24—Antigen-presenting cells [APC]
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    • C—CHEMISTRY; METALLURGY
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    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70503—Immunoglobulin superfamily
    • C07K14/70539—MHC-molecules, e.g. HLA-molecules
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/08—Linear peptides containing only normal peptide links having 12 to 20 amino acids
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
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    • C12N5/0602—Vertebrate cells
    • C12N5/0634—Cells from the blood or the immune system
    • C12N5/0636—T lymphocytes
    • C12N5/0638—Cytotoxic T lymphocytes [CTL] or lymphokine activated killer cells [LAK]
    • C—CHEMISTRY; METALLURGY
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    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
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    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/57484—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumor, cancer, neoplasia, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides, metabolites
    • G01N33/57492—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumor, cancer, neoplasia, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides, metabolites involving compounds localized on the membrane of tumor or cancer cells
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    • C—CHEMISTRY; METALLURGY
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    • C—CHEMISTRY; METALLURGY
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    • C07K—PEPTIDES
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  • Wood Science & Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
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  • Mycology (AREA)
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ES08017305.7T 2008-10-01 2008-10-01 Composición de péptidos tumor-asociados y relacionados con la vacuna contra el cáncer para el tratamiento de glioblastoma (GBM) y otros cánceres Active ES2536465T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP20080017305 EP2172211B1 (en) 2008-10-01 2008-10-01 Composition of tumor-associated peptides and related anti-cancer vaccine for the treatment of glioblastoma (GBM) and other cancers

Publications (1)

Publication Number Publication Date
ES2536465T3 true ES2536465T3 (es) 2015-05-25

Family

ID=40342382

Family Applications (12)

Application Number Title Priority Date Filing Date
ES08017305.7T Active ES2536465T3 (es) 2008-10-01 2008-10-01 Composición de péptidos tumor-asociados y relacionados con la vacuna contra el cáncer para el tratamiento de glioblastoma (GBM) y otros cánceres
ES08017921.1T Active ES2607460T3 (es) 2008-10-01 2008-10-13 Nueva inmunoterapia contra varios tumores incluidos tumores neuronales y cerebrales
ES09778750.1T Active ES2584245T3 (es) 2008-10-01 2009-09-28 Composición que comprende péptidos asociados a tumores y una vacuna para el tratamiento del glioblastoma y de otros tipos de cáncer
ES09778749.3T Active ES2612466T3 (es) 2008-10-01 2009-09-28 Composición de péptidos asociados a tumores y vacuna contra el cáncer relacionada con ellos para el tratamiento del glioblastoma (GBM) y de otros tipos de cáncer
ES16179226T Active ES2802227T3 (es) 2008-10-01 2009-09-28 Inmunoterapia novedosa contra diversos tumores, entre ellos tumores cerebrales y neuronales
ES16179174T Active ES2804723T3 (es) 2008-10-01 2009-09-28 Inmunoterapia novedosa contra diversos tumores, entre ellos tumores cerebrales y neuronales
ES16179169T Active ES2770090T3 (es) 2008-10-01 2009-09-28 Inmunoterapia novedosa contra diversos tumores, entre ellos tumores cerebrales y neuronales
ES16179241T Active ES2708654T3 (es) 2008-10-01 2009-09-28 Inmunoterapia novedosa contra varios tumores incluyendo tumores cerebrales y neuronales
ES16165070T Active ES2710608T3 (es) 2008-10-01 2009-09-28 Inmunoterapia novedosa contra diversos tumores, entre ellos tumores cerebrales y neuronales
ES16179214T Active ES2788129T3 (es) 2008-10-01 2009-09-28 Inmunoterapia novedosa contra diversos tumores, entre ellos tumores cerebrales y neuronales
ES16179192T Active ES2819244T3 (es) 2008-10-01 2009-09-28 Inmunoterapia novedosa contra diversos tumores, entre ellos tumores cerebrales y neuronales
ES16179163T Active ES2802226T3 (es) 2008-10-01 2009-09-28 Inmunoterapia novedosa contra diversos tumores, entre ellos tumores cerebrales y neuronales

Family Applications After (11)

Application Number Title Priority Date Filing Date
ES08017921.1T Active ES2607460T3 (es) 2008-10-01 2008-10-13 Nueva inmunoterapia contra varios tumores incluidos tumores neuronales y cerebrales
ES09778750.1T Active ES2584245T3 (es) 2008-10-01 2009-09-28 Composición que comprende péptidos asociados a tumores y una vacuna para el tratamiento del glioblastoma y de otros tipos de cáncer
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