ES2139043T3 - Compuestos de azaciclohexapeptidos. - Google Patents
Compuestos de azaciclohexapeptidos.Info
- Publication number
- ES2139043T3 ES2139043T3 ES94200604T ES94200604T ES2139043T3 ES 2139043 T3 ES2139043 T3 ES 2139043T3 ES 94200604 T ES94200604 T ES 94200604T ES 94200604 T ES94200604 T ES 94200604T ES 2139043 T3 ES2139043 T3 ES 2139043T3
- Authority
- ES
- Spain
- Prior art keywords
- compounds
- azaciclohexapeptide
- ceretain
- found
- preparation
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/50—Cyclic peptides containing at least one abnormal peptide link
- C07K7/54—Cyclic peptides containing at least one abnormal peptide link with at least one abnormal peptide link in the ring
- C07K7/56—Cyclic peptides containing at least one abnormal peptide link with at least one abnormal peptide link in the ring the cyclisation not occurring through 2,4-diamino-butanoic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/10—Antimycotics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
- A61P33/08—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis for Pneumocystis carinii
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S930/00—Peptide or protein sequence
- Y10S930/01—Peptide or protein sequence
- Y10S930/27—Cyclic peptide or cyclic protein
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Communicable Diseases (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Oncology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Chemical Vapour Deposition (AREA)
Abstract
COMPUESTOS DE CERETAIN AZO CICLOHEXAPEPTIDO SE HAN ENCONTRADO PARA TENER PROPIEDADES ANTIBIOTICAS SUPERIORES. NUEVOS PROCESOS PARA SU PREPARACION TAMBIEN SE DESCRIBEN.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US08/032,847 US5378804A (en) | 1993-03-16 | 1993-03-16 | Aza cyclohexapeptide compounds |
Publications (1)
Publication Number | Publication Date |
---|---|
ES2139043T3 true ES2139043T3 (es) | 2000-02-01 |
Family
ID=21867140
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES94200604T Expired - Lifetime ES2139043T3 (es) | 1993-03-16 | 1994-03-09 | Compuestos de azaciclohexapeptidos. |
Country Status (33)
Country | Link |
---|---|
US (3) | US5378804A (es) |
EP (1) | EP0620232B1 (es) |
JP (1) | JP2568474B2 (es) |
KR (1) | KR100329693B1 (es) |
CN (1) | CN1098274C (es) |
AT (1) | ATE186736T1 (es) |
AU (1) | AU668804B2 (es) |
BG (1) | BG63047B1 (es) |
BR (2) | BR9406009A (es) |
CA (1) | CA2118757C (es) |
CZ (1) | CZ286235B6 (es) |
DE (2) | DE10299013I2 (es) |
DK (1) | DK0620232T3 (es) |
ES (1) | ES2139043T3 (es) |
FI (1) | FI109542B (es) |
GR (1) | GR3031872T3 (es) |
HK (1) | HK1008674A1 (es) |
HR (1) | HRP940161B1 (es) |
HU (2) | HU217614B (es) |
IL (1) | IL108892A (es) |
LU (1) | LU90875I2 (es) |
LV (1) | LV12574B (es) |
NL (1) | NL300076I2 (es) |
NO (2) | NO318372B1 (es) |
NZ (1) | NZ263360A (es) |
PL (1) | PL179261B1 (es) |
RO (1) | RO113246B1 (es) |
RU (1) | RU2122548C1 (es) |
SI (1) | SI9420013B (es) |
SK (1) | SK282527B6 (es) |
UA (1) | UA59329C2 (es) |
WO (1) | WO1994021677A1 (es) |
ZA (1) | ZA941807B (es) |
Families Citing this family (63)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5874403A (en) * | 1992-10-15 | 1999-02-23 | Merck & Co., Inc. | Amino acid conjugates of cyclohexapeptidyl amines |
US5378804A (en) * | 1993-03-16 | 1995-01-03 | Merck & Co., Inc. | Aza cyclohexapeptide compounds |
US5948753A (en) * | 1993-05-04 | 1999-09-07 | Merck & Co., Inc. | Cyclohexapeptidyl propanolamine compounds |
CA2195975C (en) * | 1994-08-23 | 2001-05-15 | James M. Balkovec | An improved process for preparing side chain derivatives of cyclohexapeptidyl lipopeptides |
US5514651A (en) * | 1994-09-16 | 1996-05-07 | Merck & Co., Inc. | Aza cyclohexapeptide compounds |
ES2181790T3 (es) * | 1994-09-16 | 2003-03-01 | Merck & Co Inc | Compuestos azaciclohexapeptidicos. |
US5516757A (en) * | 1994-09-16 | 1996-05-14 | Merck & Co., Inc. | Semi-synthetic lipopeptides, compositions containing said lipopeptides, and methods of use |
US5516756A (en) * | 1994-10-31 | 1996-05-14 | Merck & Co., Inc. | Aza cyclohexapeptide compounds |
AU691743B2 (en) * | 1995-01-26 | 1998-05-21 | Merck & Co., Inc. | Novel antifungal cyclohexapeptides |
US5552521A (en) * | 1995-02-10 | 1996-09-03 | Merck & Co., Inc. | Process for preparing certain aza cyclohexapeptides |
AU707664B2 (en) * | 1995-11-09 | 1999-07-15 | Merck & Co., Inc. | Cyclohexapeptidyl bisamine compound, compositions containing said compound and methods of use |
US5952300A (en) * | 1996-04-19 | 1999-09-14 | Merck & Co., Inc. | Antifungal compositions |
AR006598A1 (es) * | 1996-04-19 | 1999-09-08 | Merck Sharp & Dohme | "composiciones anti-fungosas, su uso en la manufactura de medicamentos y un procedimiento para su preparación" |
HRP970318B1 (en) * | 1996-06-14 | 2002-06-30 | Merck & Co Inc | A process for preparing certain aza cyclohexapeptides |
USRE38984E1 (en) * | 1996-09-12 | 2006-02-14 | Merck & Co., Inc. | Antifungal combination therapy |
DK0925070T3 (da) * | 1996-09-12 | 2003-12-01 | Merck & Co Inc | Antifungal kombinationsterapi |
US5854212A (en) * | 1996-10-23 | 1998-12-29 | Merck & Co., Inc. | Cyclohexapeptidyl bisamine compound, compositions containing said compound and methods of use |
US5936062A (en) * | 1997-06-12 | 1999-08-10 | Merck & Co., Inc. | Process for preparing certain aza cyclohexapeptides |
US7166572B1 (en) * | 1999-07-27 | 2007-01-23 | Aventis Pharma Deutschland Gmbh | Cyclohexapeptide compounds, processes for their production and their use as a pharmaceutical |
AR035808A1 (es) * | 2001-04-12 | 2004-07-14 | Merck & Co Inc | Proceso de deshidratacion capaz de minimizar la epimerizacion de un grupo hidroxilo por ciertas equinocandinas |
AU2003217676B2 (en) | 2002-02-22 | 2009-06-11 | Takeda Pharmaceutical Company Limited | Active agent delivery systems and methods for protecting and administering active agents |
US7214768B2 (en) * | 2002-04-08 | 2007-05-08 | Merck & Co., Inc. | Echinocandin process |
ATE381957T1 (de) * | 2003-07-22 | 2008-01-15 | Theravance Inc | Verwendung eines antimykotischen echinocandin- mittels in kombination mit einem antibakteriellen glycopeptid-mittel |
CA2557333A1 (en) * | 2004-02-24 | 2005-09-01 | Commonwealth Scientific And Industrial Research Organisation | Antifungal peptides |
EP1785432A1 (en) | 2005-11-15 | 2007-05-16 | Sandoz AG | Process and intermediates for the synthesis of caspofungin. |
KR101536781B1 (ko) * | 2006-07-26 | 2015-07-14 | 산도즈 아게 | 카스포펀진 제형 |
TW200826957A (en) * | 2006-10-16 | 2008-07-01 | Teva Gyogyszergyar Zartkoruen Mukodo Reszvenytarsasag | Purification processes for echinocandin-type compounds |
WO2009002481A1 (en) | 2007-06-26 | 2008-12-31 | Merck & Co., Inc. | Lyophilized anti-fungal composition |
US20090075870A1 (en) * | 2007-09-17 | 2009-03-19 | Protia, Llc | Deuterium-enriched caspofungin |
WO2009142761A1 (en) * | 2008-05-21 | 2009-11-26 | Teva Gyogyszergyar Zartkoruen Mukodo Reszvenytarsasag | Caspofungin bo free of caspofungin co |
US8048853B2 (en) * | 2008-06-13 | 2011-11-01 | Xellia Pharmaceuticals Aps | Process for preparing pharmaceutical compound and intermediates thereof |
KR20110011704A (ko) * | 2008-06-25 | 2011-02-08 | 테바 기오기스제르갸르 자르트쾨렌 뮈쾨되 레스즈베니타르사사그 | 카스포펀진 불순물 a를 함유하지 않는 카스포펀진 |
US20100256074A1 (en) * | 2008-06-25 | 2010-10-07 | Chaim Eidelman | Processes for preparing high purity aza cyclohexapeptides |
WO2010064219A1 (en) | 2008-12-04 | 2010-06-10 | Ranbaxy Laboratories Limited | Process for the preparation of a novel intermediate for caspofungin |
TW201024322A (en) * | 2008-12-31 | 2010-07-01 | Chunghwa Chemical Synthesis & Biotech Co Ltd | Preparation method for nitrogen containing heterocyclic hexapeptide with high conversion rate |
WO2010108637A1 (en) | 2009-03-27 | 2010-09-30 | Axellia Pharmaceuticals Aps | Crystalline compound |
CN101602795B (zh) * | 2009-07-20 | 2011-12-21 | 中国人民解放军第二军医大学 | 环六脂肽胺类抗真菌化合物及其盐类和制备方法 |
US20120190815A1 (en) * | 2009-08-06 | 2012-07-26 | Tianhui Xu | Azacyclohexapeptide or its pharmaceutical acceptable salt, preparing method and use thereof |
US8751760B2 (en) * | 2009-10-01 | 2014-06-10 | Dell Products L.P. | Systems and methods for power state transitioning in an information handling system |
CN101792486A (zh) * | 2010-04-12 | 2010-08-04 | 浙江海正药业股份有限公司 | 一种合成醋酸卡泊芬净的方法 |
CN102219832B (zh) * | 2010-04-15 | 2013-08-21 | 上海天伟生物制药有限公司 | 一种氮杂环六肽或其盐的纯化方法 |
DK2618814T3 (en) | 2010-09-20 | 2016-10-10 | Xellia Pharmaceuticals Aps | Caspofunginsammensætning |
CA2813330A1 (en) * | 2010-09-29 | 2012-04-05 | Shanghai Techwell Biopharmaceutical Co., Ltd. | Process for purifying cyclolipopeptide compounds or the salts thereof |
CA2813335A1 (en) * | 2010-09-30 | 2012-04-05 | Shanghai Techwell Biopharmaceutical Co., Ltd. | Process for purifying cyclolipopeptide compounds or salts thereof |
CN102367269B (zh) | 2010-11-10 | 2013-11-06 | 上海天伟生物制药有限公司 | 一种卡泊芬净类似物及其制备方法和用途 |
CN102367267B (zh) | 2010-11-10 | 2013-09-04 | 上海天伟生物制药有限公司 | 一种卡泊芬净的制备方法 |
CN102367268B (zh) | 2010-11-10 | 2013-11-06 | 上海天伟生物制药有限公司 | 一种卡泊芬净类似物及其用途 |
KR101331984B1 (ko) | 2010-12-09 | 2013-11-25 | 종근당바이오 주식회사 | 카스포펀진 제조방법 및 그의 신규 중간체 |
WO2012093293A1 (en) * | 2011-01-03 | 2012-07-12 | Biocon Limited | Process for preparation of caspofungin acetate and intermediates |
CN102618606B (zh) * | 2011-01-30 | 2014-09-10 | 浙江海正药业股份有限公司 | 一种棘白菌素生物转化方法 |
CN103889221B (zh) | 2011-03-03 | 2016-08-31 | 西蔡德制药公司 | 抗真菌剂及其应用 |
CN102746384B (zh) | 2011-04-22 | 2016-01-20 | 上海天伟生物制药有限公司 | 一种高纯度的卡泊芬净或其盐及其制备方法和用途 |
TWI597293B (zh) | 2011-04-28 | 2017-09-01 | 江蘇盛迪醫藥有限公司 | 用於合成卡帕芬淨的中間體及其製備方法 |
KR102061486B1 (ko) | 2012-03-19 | 2020-01-03 | 시다라 세라퓨틱스, 인코포레이티드 | 에키노칸딘 계열의 화합물에 대한 투여 용법 |
HUE032392T2 (en) | 2012-11-20 | 2017-09-28 | Fresenius Kabi Usa Llc | Kaszpofunginacetát compositions |
CN112110991A (zh) * | 2014-12-24 | 2020-12-22 | 上海天伟生物制药有限公司 | 一种含氮杂环六肽前体的组合物及其制备方法和用途 |
WO2017034961A1 (en) | 2015-08-21 | 2017-03-02 | Trilogy Therapeutics, Inc. | Methods of treating lung infection with caspofungin |
WO2017120471A1 (en) | 2016-01-08 | 2017-07-13 | Cidara Therapeutics, Inc. | Methods for preventing and treating pneumocystis infections |
CN109154603A (zh) | 2016-03-16 | 2019-01-04 | 奇达拉治疗公司 | 用于治疗真菌感染的给药方案 |
WO2017185030A1 (en) * | 2016-04-22 | 2017-10-26 | Fresenius Kabi Usa, Llc | Caspofungin formulation with low impurities |
WO2019014333A1 (en) | 2017-07-12 | 2019-01-17 | Cidara Therapeutics, Inc. | COMPOSITIONS AND METHODS FOR THE TREATMENT OF FUNGAL INFECTIONS |
WO2019157453A1 (en) | 2018-02-12 | 2019-08-15 | Trilogy Therapeutics, Inc. | Caspofungin compositions for inhalation |
EP3620462A1 (en) | 2018-09-04 | 2020-03-11 | Xellia Pharmaceuticals ApS | Process for the preparation of caspofungin |
Family Cites Families (22)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE2704030A1 (de) * | 1976-02-12 | 1977-08-18 | Sandoz Ag | Neue organische verbindungen, ihre herstellung und verwendung |
BE851310A (fr) * | 1976-02-12 | 1977-08-10 | Sandoz Sa | Nouveaux derives de la tetrahydro-equinocandine b |
DE2742435A1 (de) * | 1976-09-28 | 1978-04-06 | Sandoz Ag | Aminoalkylaether der peptide tetrahydro- sl 7810/f-ii, s 31794/f-1, aculeacin a und tetrahydroechinocandin b, ihre verwendung und herstellung |
US4293485A (en) * | 1979-12-13 | 1981-10-06 | Eli Lilly And Company | Derivatives of S31794/F-1 nucleus |
EP0030844A1 (en) * | 1979-12-13 | 1981-06-24 | Eli Lilly And Company | Recovery process for A-30912 antibiotics |
US4320053A (en) * | 1979-12-13 | 1982-03-16 | Eli Lilly And Company | Derivatives of A-30912D nucleus |
US4287120A (en) * | 1979-12-13 | 1981-09-01 | Eli Lilly And Company | Derivatives of S31794/F-1 nucleus |
US4293489A (en) * | 1979-12-13 | 1981-10-06 | Eli Lilly And Company | Derivatives of A-30912A nucleus |
DE3030554A1 (de) * | 1980-08-13 | 1982-03-25 | Chemische Werke Hüls AG, 4370 Marl | Einbrennlacke |
US4931352A (en) * | 1987-10-07 | 1990-06-05 | Merck & Co., Inc. | Antifungal fermentation product |
US5166135A (en) * | 1988-09-12 | 1992-11-24 | Merck & Company, Inc. | Method for the control of pneumocystis carinii |
DK173802B1 (da) * | 1988-09-12 | 2001-11-05 | Merck & Co Inc | Præparat til behandling af Pneumocystis carinii infeksioner og anvendelse af et cyclohexapeptid til fremstilling af et lægemiddel mod Pneumocystis carinii infektioner |
US5021341A (en) * | 1990-03-12 | 1991-06-04 | Merck & Co., Inc. | Antibiotic agent produced by the cultivation of Zalerion microorganism in the presence of mannitol |
NZ234225A (en) * | 1989-06-30 | 1993-09-27 | Merck & Co Inc | Antibiotic from zalerion arboricola and its use as an antifungal agent and antipneumocystis agent |
US5202309A (en) * | 1989-06-30 | 1993-04-13 | Merck & Co., Inc. | Antibiotic cyclopeptide fermentation product |
US5194377A (en) * | 1989-06-30 | 1993-03-16 | Merck & Co., Inc. | Antibiotic agent |
GB8925593D0 (en) * | 1989-11-13 | 1990-01-04 | Fujisawa Pharmaceutical Co | Fr901379 substance and preparation thereof |
US5159059A (en) * | 1990-05-29 | 1992-10-27 | Merck & Co., Inc. | Process for reduction of certain cyclohexapeptide compounds |
TW264477B (es) * | 1992-03-19 | 1995-12-01 | Lilly Co Eli | |
US5378804A (en) * | 1993-03-16 | 1995-01-03 | Merck & Co., Inc. | Aza cyclohexapeptide compounds |
US5516757A (en) * | 1994-09-16 | 1996-05-14 | Merck & Co., Inc. | Semi-synthetic lipopeptides, compositions containing said lipopeptides, and methods of use |
US5516756A (en) * | 1994-10-31 | 1996-05-14 | Merck & Co., Inc. | Aza cyclohexapeptide compounds |
-
1993
- 1993-03-16 US US08/032,847 patent/US5378804A/en not_active Expired - Lifetime
-
1994
- 1994-03-08 IL IL10889294A patent/IL108892A/en not_active IP Right Cessation
- 1994-03-09 DK DK94200604T patent/DK0620232T3/da active
- 1994-03-09 EP EP94200604A patent/EP0620232B1/en not_active Expired - Lifetime
- 1994-03-09 DE DE10299013C patent/DE10299013I2/de active Active
- 1994-03-09 AT AT94200604T patent/ATE186736T1/de active
- 1994-03-09 DE DE69421639T patent/DE69421639T2/de not_active Expired - Lifetime
- 1994-03-09 ES ES94200604T patent/ES2139043T3/es not_active Expired - Lifetime
- 1994-03-10 BR BR9406009A patent/BR9406009A/pt not_active Application Discontinuation
- 1994-03-10 WO PCT/US1994/002580 patent/WO1994021677A1/en active IP Right Grant
- 1994-03-10 NZ NZ263360A patent/NZ263360A/xx not_active IP Right Cessation
- 1994-03-10 KR KR1019950703954A patent/KR100329693B1/ko active IP Right Grant
- 1994-03-10 HU HU9502703A patent/HU217614B/hu unknown
- 1994-03-10 HR HR940161A patent/HRP940161B1/xx not_active IP Right Cessation
- 1994-03-10 CZ CZ19952358A patent/CZ286235B6/cs not_active IP Right Cessation
- 1994-03-10 RU RU95121639A patent/RU2122548C1/ru active
- 1994-03-10 RO RO95-01594A patent/RO113246B1/ro unknown
- 1994-03-10 CA CA002118757A patent/CA2118757C/en not_active Expired - Lifetime
- 1994-03-10 SK SK1136-95A patent/SK282527B6/sk not_active IP Right Cessation
- 1994-03-10 SI SI9420013A patent/SI9420013B/sl unknown
- 1994-03-10 CN CN94191487A patent/CN1098274C/zh not_active Expired - Lifetime
- 1994-03-10 PL PL94310634A patent/PL179261B1/pl unknown
- 1994-03-15 ZA ZA941807A patent/ZA941807B/xx unknown
- 1994-03-15 JP JP6044091A patent/JP2568474B2/ja not_active Expired - Lifetime
- 1994-03-15 AU AU57832/94A patent/AU668804B2/en not_active Expired
- 1994-08-29 US US08/298,479 patent/US5514650A/en not_active Expired - Lifetime
- 1994-10-03 UA UA95094151A patent/UA59329C2/uk unknown
-
1995
- 1995-06-29 HU HU95P/P00565P patent/HU211890A9/hu unknown
- 1995-09-13 BG BG99999A patent/BG63047B1/bg unknown
- 1995-09-14 FI FI954327A patent/FI109542B/fi not_active IP Right Cessation
- 1995-09-15 NO NO19953648A patent/NO318372B1/no not_active IP Right Cessation
-
1996
- 1996-10-28 US US08/741,645 patent/US5792746A/en not_active Expired - Lifetime
-
1997
- 1997-04-16 BR BR1100273-5A patent/BR1100273A/pt active IP Right Grant
-
1998
- 1998-07-20 HK HK98109267A patent/HK1008674A1/xx not_active IP Right Cessation
-
1999
- 1999-11-18 GR GR990402878T patent/GR3031872T3/el unknown
-
2000
- 2000-09-07 LV LVP-00-119A patent/LV12574B/en unknown
-
2001
- 2001-12-18 NL NL300076C patent/NL300076I2/nl unknown
-
2002
- 2002-01-03 LU LU90875C patent/LU90875I2/xx unknown
-
2005
- 2005-09-13 NO NO2005020C patent/NO2005020I2/no unknown
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