ES2139043T3 - Compuestos de azaciclohexapeptidos. - Google Patents

Compuestos de azaciclohexapeptidos.

Info

Publication number
ES2139043T3
ES2139043T3 ES94200604T ES94200604T ES2139043T3 ES 2139043 T3 ES2139043 T3 ES 2139043T3 ES 94200604 T ES94200604 T ES 94200604T ES 94200604 T ES94200604 T ES 94200604T ES 2139043 T3 ES2139043 T3 ES 2139043T3
Authority
ES
Spain
Prior art keywords
compounds
azaciclohexapeptide
ceretain
found
preparation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES94200604T
Other languages
English (en)
Inventor
James M Balkovec
Frances Aileen Bouffard
Regina M Black
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck and Co Inc
Original Assignee
Merck and Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=21867140&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ES2139043(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Merck and Co Inc filed Critical Merck and Co Inc
Application granted granted Critical
Publication of ES2139043T3 publication Critical patent/ES2139043T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/50—Cyclic peptides containing at least one abnormal peptide link
    • C07K7/54—Cyclic peptides containing at least one abnormal peptide link with at least one abnormal peptide link in the ring
    • C07K7/56—Cyclic peptides containing at least one abnormal peptide link with at least one abnormal peptide link in the ring the cyclisation not occurring through 2,4-diamino-butanoic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10—Antimycotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • A61P33/08—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis for Pneumocystis carinii
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S930/00—Peptide or protein sequence
    • Y10S930/01—Peptide or protein sequence
    • Y10S930/27—Cyclic peptide or cyclic protein

Abstract

COMPUESTOS DE CERETAIN AZO CICLOHEXAPEPTIDO SE HAN ENCONTRADO PARA TENER PROPIEDADES ANTIBIOTICAS SUPERIORES. NUEVOS PROCESOS PARA SU PREPARACION TAMBIEN SE DESCRIBEN.
ES94200604T 1993-03-16 1994-03-09 Compuestos de azaciclohexapeptidos. Expired - Lifetime ES2139043T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US08/032,847 US5378804A (en) 1993-03-16 1993-03-16 Aza cyclohexapeptide compounds

Publications (1)

Publication Number Publication Date
ES2139043T3 true ES2139043T3 (es) 2000-02-01

Family

ID=21867140

Family Applications (1)

Application Number Title Priority Date Filing Date
ES94200604T Expired - Lifetime ES2139043T3 (es) 1993-03-16 1994-03-09 Compuestos de azaciclohexapeptidos.

Country Status (33)

Country Link
US (3) US5378804A (es)
EP (1) EP0620232B1 (es)
JP (1) JP2568474B2 (es)
KR (1) KR100329693B1 (es)
CN (1) CN1098274C (es)
AT (1) ATE186736T1 (es)
AU (1) AU668804B2 (es)
BG (1) BG63047B1 (es)
BR (2) BR9406009A (es)
CA (1) CA2118757C (es)
CZ (1) CZ286235B6 (es)
DE (2) DE69421639T2 (es)
DK (1) DK0620232T3 (es)
ES (1) ES2139043T3 (es)
FI (1) FI109542B (es)
GR (1) GR3031872T3 (es)
HK (1) HK1008674A1 (es)
HR (1) HRP940161B1 (es)
HU (2) HU217614B (es)
IL (1) IL108892A (es)
LU (1) LU90875I2 (es)
LV (1) LV12574B (es)
NL (1) NL300076I2 (es)
NO (2) NO318372B1 (es)
NZ (1) NZ263360A (es)
PL (1) PL179261B1 (es)
RO (1) RO113246B1 (es)
RU (1) RU2122548C1 (es)
SI (1) SI9420013B (es)
SK (1) SK282527B6 (es)
UA (1) UA59329C2 (es)
WO (1) WO1994021677A1 (es)
ZA (1) ZA941807B (es)

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ES2181790T3 (es) * 1994-09-16 2003-03-01 Merck & Co Inc Compuestos azaciclohexapeptidicos.
US5516756A (en) * 1994-10-31 1996-05-14 Merck & Co., Inc. Aza cyclohexapeptide compounds
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US5952300A (en) * 1996-04-19 1999-09-14 Merck & Co., Inc. Antifungal compositions
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US20090075870A1 (en) * 2007-09-17 2009-03-19 Protia, Llc Deuterium-enriched caspofungin
US20090291996A1 (en) * 2008-05-21 2009-11-26 Ferenc Korodi Caspofungin free of caspofungin Co
US8048853B2 (en) * 2008-06-13 2011-11-01 Xellia Pharmaceuticals Aps Process for preparing pharmaceutical compound and intermediates thereof
CN102076707A (zh) * 2008-06-25 2011-05-25 特瓦药厂私人有限公司 无卡泊芬净杂质a的卡泊芬净
EP2240507A2 (en) * 2008-06-25 2010-10-20 TEVA Gyógyszergyár Zártkörüen Müködö Részvénytársaság Processes for preparing high purity aza cyclohexapeptides
WO2010064219A1 (en) 2008-12-04 2010-06-10 Ranbaxy Laboratories Limited Process for the preparation of a novel intermediate for caspofungin
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WO2010108637A1 (en) 2009-03-27 2010-09-30 Axellia Pharmaceuticals Aps Crystalline compound
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CN102367269B (zh) 2010-11-10 2013-11-06 上海天伟生物制药有限公司 一种卡泊芬净类似物及其制备方法和用途
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Also Published As

Publication number Publication date
IL108892A0 (en) 1994-06-24
PL310634A1 (en) 1995-12-27
HU211890A9 (en) 1995-12-28
DE10299013I2 (de) 2009-11-19
KR100329693B1 (ko) 2002-08-14
NO953648L (no) 1995-11-15
GR3031872T3 (en) 2000-02-29
JP2568474B2 (ja) 1997-01-08
ATE186736T1 (de) 1999-12-15
NO953648D0 (no) 1995-09-15
PL179261B1 (pl) 2000-08-31
IL108892A (en) 1998-07-15
CN1119441A (zh) 1996-03-27
US5514650A (en) 1996-05-07
NL300076I2 (nl) 2002-04-02
HRP940161B1 (en) 2001-04-30
FI109542B (fi) 2002-08-30
JPH06321986A (ja) 1994-11-22
KR960701092A (ko) 1996-02-24
NO318372B1 (no) 2005-03-14
FI954327A0 (fi) 1995-09-14
UA59329C2 (uk) 2003-09-15
HK1008674A1 (en) 1999-05-14
DE69421639T2 (de) 2000-06-08
RU2122548C1 (ru) 1998-11-27
CA2118757C (en) 2002-05-14
CZ286235B6 (cs) 2000-02-16
BR9406009A (pt) 1995-12-26
RO113246B1 (ro) 1998-05-29
BG63047B1 (bg) 2001-02-28
SK282527B6 (sk) 2002-10-08
CA2118757A1 (en) 1994-09-17
SK113695A3 (en) 1996-02-07
NZ263360A (en) 1997-08-22
SI9420013A (en) 1996-08-31
SI9420013B (sl) 2002-12-31
US5792746A (en) 1998-08-11
AU5783294A (en) 1994-09-22
EP0620232A1 (en) 1994-10-19
WO1994021677A1 (en) 1994-09-29
ZA941807B (en) 1994-10-13
BR1100273A (pt) 1999-10-13
EP0620232B1 (en) 1999-11-17
FI954327A (fi) 1995-09-14
DE69421639D1 (de) 1999-12-23
BG99999A (bg) 1996-04-30
DK0620232T3 (da) 2000-03-13
NO2005020I1 (no) 2005-09-13
CN1098274C (zh) 2003-01-08
LV12574A (en) 2000-11-20
HUT73496A (en) 1996-08-28
LU90875I2 (en) 2002-03-04
AU668804B2 (en) 1996-05-16
HU217614B (hu) 2000-03-28
LV12574B (en) 2001-04-20
US5378804A (en) 1995-01-03
DE10299013I1 (de) 2003-01-23
HU9502703D0 (en) 1995-11-28
NL300076I1 (nl) 2002-03-01
CZ235895A3 (en) 1996-02-14
HRP940161A2 (en) 1996-08-31
NO2005020I2 (no) 2008-12-01

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