AR012449A1 - Kodaistatinas a, b, c y d, proceso para su produccion, y su uso. - Google Patents

Kodaistatinas a, b, c y d, proceso para su produccion, y su uso.

Info

Publication number
AR012449A1
AR012449A1 ARP980101757A ARP980101757A AR012449A1 AR 012449 A1 AR012449 A1 AR 012449A1 AR P980101757 A ARP980101757 A AR P980101757A AR P980101757 A ARP980101757 A AR P980101757A AR 012449 A1 AR012449 A1 AR 012449A1
Authority
AR
Argentina
Prior art keywords
kodaistatinas
production
kodaistatins
compounds
molecular formula
Prior art date
Application number
ARP980101757A
Other languages
English (en)
Original Assignee
Hoechst Marion Roussell Deutschland Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Marion Roussell Deutschland Gmbh filed Critical Hoechst Marion Roussell Deutschland Gmbh
Publication of AR012449A1 publication Critical patent/AR012449A1/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D307/56—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D307/60—Two oxygen atoms, e.g. succinic anhydride
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/02—Separating microorganisms from their culture media

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Medicinal Chemistry (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Diabetes (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Virology (AREA)
  • Epidemiology (AREA)
  • Biomedical Technology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Emergency Medicine (AREA)
  • Endocrinology (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Compounds Of Unknown Constitution (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)

Abstract

Kodaistatinas A, B, C y D, un proceso para su produccion, y su uso. Las Kodaistatinas A y b, compuestos de la formula (I), a continuacion, con laformula molecular C35H34O11, y las Kodaistatinas C y D, compuestos de la formula molecular C35H34O12, tienen actividad anti-diabética.
ARP980101757A 1997-04-18 1998-04-16 Kodaistatinas a, b, c y d, proceso para su produccion, y su uso. AR012449A1 (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP97106453 1997-04-18
EP97109900 1997-06-18
EP97120536 1997-11-24

Publications (1)

Publication Number Publication Date
AR012449A1 true AR012449A1 (es) 2000-10-18

Family

ID=27238189

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP980101757A AR012449A1 (es) 1997-04-18 1998-04-16 Kodaistatinas a, b, c y d, proceso para su produccion, y su uso.

Country Status (14)

Country Link
US (1) US6166070A (es)
EP (1) EP0973760B1 (es)
JP (1) JP3993643B2 (es)
CN (1) CN1252797A (es)
AR (1) AR012449A1 (es)
AT (1) ATE227711T1 (es)
AU (1) AU736137B2 (es)
BR (1) BR9809104A (es)
CA (1) CA2286822C (es)
DE (1) DE69809405T2 (es)
DK (1) DK0973760T3 (es)
ES (1) ES2186164T3 (es)
PT (1) PT973760E (es)
WO (1) WO1998047888A1 (es)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EE200200216A (et) 1999-10-25 2003-06-16 Aventis Pharma Deutschland Gmbh Aromaatsed diketoderivaadid, nende valmistamismeetodid ja farmatseutiline kompositsioon
CN108929293B (zh) * 2017-05-25 2021-08-13 上海交通大学医学院附属仁济医院 丁烯酸内酯类化合物的制备方法和用途

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TW399041B (en) * 1992-09-09 2000-07-21 Hoechst Ag Substituted cyclohexane derivatives, the preparation and the use for treating diseases
TW255880B (es) * 1992-09-09 1995-09-01 Hoechst Ag
JPH09202797A (ja) * 1996-01-24 1997-08-05 Sankyo Co Ltd ５α−還元酵素阻害化合物ｄ１０６７３３１

Also Published As

Publication number Publication date
CA2286822C (en) 2008-07-29
DK0973760T3 (da) 2003-03-03
JP2001524092A (ja) 2001-11-27
EP0973760B1 (en) 2002-11-13
AU736137B2 (en) 2001-07-26
PT973760E (pt) 2003-03-31
AU7644298A (en) 1998-11-13
DE69809405D1 (de) 2002-12-19
BR9809104A (pt) 2000-08-01
CA2286822A1 (en) 1998-10-29
JP3993643B2 (ja) 2007-10-17
ATE227711T1 (de) 2002-11-15
ES2186164T3 (es) 2003-05-01
CN1252797A (zh) 2000-05-10
US6166070A (en) 2000-12-26
WO1998047888A1 (en) 1998-10-29
EP0973760A1 (en) 2000-01-26
DE69809405T2 (de) 2003-07-10

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