BR9809104A - Codaistatinas a, b, c e d, processo para sua produção e seu uso - Google Patents

Codaistatinas a, b, c e d, processo para sua produção e seu uso

Info

Publication number
BR9809104A
BR9809104A BR9809104-2A BR9809104A BR9809104A BR 9809104 A BR9809104 A BR 9809104A BR 9809104 A BR9809104 A BR 9809104A BR 9809104 A BR9809104 A BR 9809104A
Authority
BR
Brazil
Prior art keywords
codaistatins
production
compounds
molecular formula
codaistatines
Prior art date
Application number
BR9809104-2A
Other languages
English (en)
Inventor
Nirogi Venkata Sat Ramakrishna
Keshavapura Hosamane Sre Swamy
Erra Koteswara Sat Vijayakumar
Suresh Rudra Nadkarni
Kenia Jayvanti
Andreas W Herling
Herbert Kogler
Laszlo Vertesy
Rajan Mukund Panshikar
Kota Sridevi
Mythili Raman
Roda Maneck Dalal
Original Assignee
Hoechst Marion Roussel Deutisc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Marion Roussel Deutisc filed Critical Hoechst Marion Roussel Deutisc
Publication of BR9809104A publication Critical patent/BR9809104A/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D307/56—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D307/60—Two oxygen atoms, e.g. succinic anhydride
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/02—Separating microorganisms from their culture media

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Diabetes (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Epidemiology (AREA)
  • Biomedical Technology (AREA)
  • Virology (AREA)
  • Emergency Medicine (AREA)
  • Endocrinology (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Compounds Of Unknown Constitution (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)

Abstract

Patente de Invenção: <B>''CODAISTATINAS A, B, C E D, PROCESSO PARA SUA PRODUçãO E SEU USO''<D>. Codaistatinas A e B, compostos da fórmula molecular C~ 35~H~ 34~O~ 11~, e codaistatinas C e D, compostos da fórmula molecular C~ 35~H~ 34~O~ 12~, possuem atividade antidiabética.
BR9809104-2A 1997-04-18 1998-04-17 Codaistatinas a, b, c e d, processo para sua produção e seu uso BR9809104A (pt)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
EP97106453 1997-04-18
EP97109900 1997-06-18
EP97120536 1997-11-24
PCT/EP1998/002247 WO1998047888A1 (en) 1997-04-18 1998-04-17 Kodaistatins a, b, c and d, a process for their production and their use

Publications (1)

Publication Number Publication Date
BR9809104A true BR9809104A (pt) 2000-08-01

Family

ID=27238189

Family Applications (1)

Application Number Title Priority Date Filing Date
BR9809104-2A BR9809104A (pt) 1997-04-18 1998-04-17 Codaistatinas a, b, c e d, processo para sua produção e seu uso

Country Status (14)

Country Link
US (1) US6166070A (pt)
EP (1) EP0973760B1 (pt)
JP (1) JP3993643B2 (pt)
CN (1) CN1252797A (pt)
AR (1) AR012449A1 (pt)
AT (1) ATE227711T1 (pt)
AU (1) AU736137B2 (pt)
BR (1) BR9809104A (pt)
CA (1) CA2286822C (pt)
DE (1) DE69809405T2 (pt)
DK (1) DK0973760T3 (pt)
ES (1) ES2186164T3 (pt)
PT (1) PT973760E (pt)
WO (1) WO1998047888A1 (pt)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RS50431B (sr) * 1999-10-25 2009-12-31 Sanofi-Aventis Deutschland Gmbh., Derivati aromatičnih di-ketona, postupci za njihovu izradu i njihova upotreba kao farmaceutskih proizvoda
CN108929293B (zh) * 2017-05-25 2021-08-13 上海交通大学医学院附属仁济医院 丁烯酸内酯类化合物的制备方法和用途

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TW399041B (en) * 1992-09-09 2000-07-21 Hoechst Ag Substituted cyclohexane derivatives, the preparation and the use for treating diseases
TW255880B (pt) * 1992-09-09 1995-09-01 Hoechst Ag
JPH09202797A (ja) * 1996-01-24 1997-08-05 Sankyo Co Ltd ５α−還元酵素阻害化合物ｄ１０６７３３１

Also Published As

Publication number Publication date
DK0973760T3 (da) 2003-03-03
EP0973760A1 (en) 2000-01-26
JP3993643B2 (ja) 2007-10-17
AR012449A1 (es) 2000-10-18
ATE227711T1 (de) 2002-11-15
CN1252797A (zh) 2000-05-10
AU7644298A (en) 1998-11-13
EP0973760B1 (en) 2002-11-13
PT973760E (pt) 2003-03-31
AU736137B2 (en) 2001-07-26
US6166070A (en) 2000-12-26
ES2186164T3 (es) 2003-05-01
DE69809405T2 (de) 2003-07-10
JP2001524092A (ja) 2001-11-27
CA2286822C (en) 2008-07-29
DE69809405D1 (de) 2002-12-19
CA2286822A1 (en) 1998-10-29
WO1998047888A1 (en) 1998-10-29

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Legal Events

Date Code Title Description
TC Change of name
B08K Patent lapsed as no evidence of payment of the annual fee has been furnished to inpi [chapter 8.11 patent gazette]

Free format text: REFERENTE AO DESPACHO 8.6 PUBLICADO NA RPI 1891 DE 03/04/2007.