DK0411733T3 - 11-beta-aryl-gona-4,9-dien-3-oner - Google Patents
11-beta-aryl-gona-4,9-dien-3-onerInfo
- Publication number
- DK0411733T3 DK0411733T3 DK90250199T DK90250199T DK0411733T3 DK 0411733 T3 DK0411733 T3 DK 0411733T3 DK 90250199 T DK90250199 T DK 90250199T DK 90250199 T DK90250199 T DK 90250199T DK 0411733 T3 DK0411733 T3 DK 0411733T3
- Authority
- DK
- Denmark
- Prior art keywords
- gona
- beta
- aryl
- dien
- ones
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
- C07J1/0051—Estrane derivatives
- C07J1/0081—Substituted in position 17 alfa and 17 beta
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/04—Drugs for genital or sexual disorders; Contraceptives for inducing labour or abortion; Uterotonics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
- A61P5/36—Antigestagens
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
- C07J1/0051—Estrane derivatives
- C07J1/0081—Substituted in position 17 alfa and 17 beta
- C07J1/0088—Substituted in position 17 alfa and 17 beta the substituent in position 17 alfa being an unsaturated hydrocarbon group
- C07J1/0092—Alkenyl derivatives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
- C07J1/0051—Estrane derivatives
- C07J1/0081—Substituted in position 17 alfa and 17 beta
- C07J1/0088—Substituted in position 17 alfa and 17 beta the substituent in position 17 alfa being an unsaturated hydrocarbon group
- C07J1/0096—Alkynyl derivatives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
- C07J41/0033—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005
- C07J41/0077—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 substituted in position 11-beta by a carbon atom, further substituted by a group comprising at least one further carbon atom
- C07J41/0083—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 substituted in position 11-beta by a carbon atom, further substituted by a group comprising at least one further carbon atom substituted in position 11-beta by an optionally substituted phenyl group not further condensed with other rings
Landscapes
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Endocrinology (AREA)
- Reproductive Health (AREA)
- Neurosurgery (AREA)
- Urology & Nephrology (AREA)
- Pain & Pain Management (AREA)
- Diabetes (AREA)
- Biomedical Technology (AREA)
- Gynecology & Obstetrics (AREA)
- Pregnancy & Childbirth (AREA)
- Neurology (AREA)
- Steroid Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Luminescent Compositions (AREA)
- Die Bonding (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Holo Graphy (AREA)
- Powder Metallurgy (AREA)
- Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
- Carbon And Carbon Compounds (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DD33147989A DD290893A5 (de) | 1989-08-04 | 1989-08-04 | Verfahren zur herstellung von 11 beta-aryl-estra-4,9-dien-3-onen |
DD33181889A DD289537A5 (de) | 1989-08-16 | 1989-08-16 | Verfahren zur herstellung von 11 beta-aryl-gona-4,9-dienen |
DD33340989A DD299068A5 (de) | 1989-10-09 | 1989-10-09 | Verfahren zur herstellung von 11 beta-arylsubstituierten 17 beta-alkoxy-17 alpha -alkoxymethyl-estra-4,9-dien-3-onen |
Publications (1)
Publication Number | Publication Date |
---|---|
DK0411733T3 true DK0411733T3 (da) | 1999-06-28 |
Family
ID=27179934
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK90250199T DK0411733T3 (da) | 1989-08-04 | 1990-08-06 | 11-beta-aryl-gona-4,9-dien-3-oner |
Country Status (7)
Country | Link |
---|---|
EP (1) | EP0411733B1 (da) |
JP (1) | JP3202224B2 (da) |
AT (1) | ATE172469T1 (da) |
DE (1) | DE59010853D1 (da) |
DK (1) | DK0411733T3 (da) |
ES (1) | ES2127181T3 (da) |
WO (1) | WO1991001958A2 (da) |
Families Citing this family (17)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE4332284C2 (de) * | 1993-09-20 | 1997-05-28 | Jenapharm Gmbh | 11-Benzaldoxim-17beta-methoxy-17alpha-methoxymethyl-estradien-Derivate, Verfahren zu ihrer Herstellung und diese Verbindungen enthaltende Arzneimittel |
DE4332283A1 (de) * | 1993-09-20 | 1995-04-13 | Jenapharm Gmbh | Neue 11-Benzaldoximestradien-Derivate, Verfahren zu ihrer Herstellung und diese Verbindungen enthaltende Arzneimittel |
IL123195A (en) * | 1997-02-21 | 2002-11-10 | Akzo Nobel Nv | Steroid compounds with anti-pregnancy activity and against bone thinning, preparation and pharmaceutical preparations containing them |
US6020328A (en) * | 1998-03-06 | 2000-02-01 | Research Triangle Institute | 20-keto-11β-arylsteroids and their derivatives having agonist or antagonist hormonal properties |
US5962444A (en) * | 1998-05-29 | 1999-10-05 | Research Triangle Institute | 17β-nitro-11β-arylsteroids and their derivatives having agonist or antagonist hormonal properties |
US6262042B1 (en) | 1998-05-29 | 2001-07-17 | Research Triangle Institute | 17β-amino and hydroxylamino-11β-arylsteroids and their derivatives having agonist or antagonist hormonal properties |
US6172052B1 (en) * | 1998-12-04 | 2001-01-09 | Research Triangle Institute | 17β-acyl-17α-propynyl-11β-arylsteroids and their derivatives having agonist or antagonist hormonal properties |
DE102006018869A1 (de) * | 2006-04-13 | 2007-10-18 | Bayer Schering Pharma Ag | 17alpha-substituierte 4-(3-Oxoestra-4,9-dien-11beta-yl)-benzoesäure, deren Derivate und Verfahren zu ihrer Herstellung |
EP1862468A1 (de) | 2006-06-02 | 2007-12-05 | Bayer Schering Pharma Aktiengesellschaft | Kristallines 11beta-(4-Acetylphenyl)-20,20,21,21,21-pentafluor-17-hydroxy-19-nor-17alpha-pregna-4,9-dien-3-on |
DE102009034362A1 (de) | 2009-07-20 | 2011-01-27 | Bayer Schering Pharma Aktiengesellschaft | 17-Hydroxy-17-pentafluorethyl-estra-4,9(10)-dien-11-aryl-Derivate, Verfahren zu ihrer Herstellung und ihre Verwendung zur Behandlung von Krankheiten |
DE102009034368A1 (de) | 2009-07-20 | 2011-01-27 | Bayer Schering Pharma Aktiengesellschaft | 17-Hydroxy-17-pentafluorethyl-estra-4,9(10)-dien-11-acyloxyalkylenphenyl-Derivate, Verfahren zu ihrer Herstellung und ihre Verwendung zur Behandlung von Krankheiten |
DE102009034366A1 (de) | 2009-07-20 | 2011-01-27 | Bayer Schering Pharma Aktiengesellschaft | 17-Hydroxy-17-pentafluorethyl-estra-4,9(10)-dien-11-methylenoxyalkylenaryl-Derivate, Verfahren zu ihrer Herstellung und ihre Verwendung zur Behandlung von Krankheiten |
DE102009034367A1 (de) | 2009-07-20 | 2011-01-27 | Bayer Schering Pharma Aktiengesellschaft | 17-Hydroxy-17-pentafluorethyl-estra-4,9(10)-dien-11-benzyliden-Derivate, Verfahren zu deren Herstellung und deren Verwendung zur Behandlung von Krankheiten |
DE102009034526A1 (de) | 2009-07-21 | 2011-02-10 | Bayer Schering Pharma Aktiengesellschaft | 17-Hydroxy-17-pentafluorethyl-estra-4,9(10)-dien-11-ethinylphenyl-Derivate, Verfahren zu deren Herstellung und deren Verwendung zur Behandlung von Krankheiten |
DE102009034525A1 (de) | 2009-07-21 | 2011-01-27 | Bayer Schering Pharma Aktiengesellschaft | 17-Hydroxy-17-pentafluorethyl-estra-4,9(10)-dien-11-aryl-Derivate, Verfahren zu ihrer Herstellung und ihre Verwendung zur Behandlung von Krankheiten |
DE102010007722A1 (de) | 2010-02-10 | 2011-08-11 | Bayer Schering Pharma Aktiengesellschaft, 13353 | Progesteronrezeptorantagonisten |
DE102010007719A1 (de) | 2010-02-10 | 2011-08-11 | Bayer Schering Pharma Aktiengesellschaft, 13353 | Progesteronrezeptorantagonisten |
Family Cites Families (19)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2528434B1 (fr) * | 1982-06-11 | 1985-07-19 | Roussel Uclaf | Nouveaux 19-nor steroides substitues en 11b et eventuellement en 2, leur procede de preparation et leur application comme medicament |
EP0110434B1 (fr) * | 1981-01-09 | 1986-10-29 | Roussel-Uclaf | Nouveaux produits intermédiaires stéroides substitués en 11-beta et procédé de préparation de ces produits |
FR2522328B1 (fr) * | 1982-03-01 | 1986-02-14 | Roussel Uclaf | Nouveaux produits derives de la structure 3-ceto 4,9 19-nor steroides, leur procede de preparation et leur application comme medicaments |
DE3231827A1 (de) * | 1982-08-24 | 1984-03-01 | Schering AG, 1000 Berlin und 4709 Bergkamen | 11ss-aryl-17(alpha)-alkinyl-17ss-hydroxy-4,9(10)- estradien-3-on-derivate, deren herstellung und diese enthaltende pharmazeutische praeparate |
FR2549067B1 (fr) * | 1983-06-14 | 1985-12-27 | Roussel Uclaf | Derives estradieniques radioactifs marques au tritium, leur procede de preparation et leur application pour l'etude et le dosage radio-immunologique de steroides dans les fluides biologiques |
ES8502612A1 (es) * | 1983-06-15 | 1985-02-01 | Schering Ag | Procedimiento para la preparacion de 13a-alquilgonanos |
DE3347126A1 (de) * | 1983-12-22 | 1985-07-11 | Schering AG, 1000 Berlin und 4709 Bergkamen | 11ss-aryl-estradiene, deren herstellung und diese enthaltende pharmazeutische praeparate |
FR2566779B2 (fr) * | 1984-06-29 | 1987-03-06 | Roussel Uclaf | Nouveaux derives steroides substitues en 11b, leur procede de preparation et leur application comme medicaments |
FR2573657B1 (fr) * | 1984-11-29 | 1989-05-12 | Roussel Uclaf | Produit comprenant une substance antiprogestomimetique et une substance uterotonique |
NZ214998A (en) * | 1985-02-07 | 1989-06-28 | Schering Ag | 13-(methyl or ethyl)-11-beta-phenyl-gonane derivatives; preparatory processes and pharmaceutical compositions |
FR2586021B1 (fr) * | 1985-08-09 | 1988-10-14 | Roussel Uclaf | Nouveaux produits derives de la structure 5a-oh d 9(10) 19-nor steroides |
DE3625315A1 (de) * | 1986-07-25 | 1988-01-28 | Schering Ag | 11ss-(4-isopropenylphenyl)-estra-4,9-diene, deren herstellung und diese enthaltende pharmazeutische praeparate |
IE60780B1 (en) * | 1987-01-23 | 1994-08-10 | Akzo Nv | New 11-aryl steroid derivatives |
EP0289073B1 (en) * | 1987-04-24 | 1991-11-27 | Akzo N.V. | Novel 11-aryloestrane and 11-arylpregnane derivatives |
DE3723788A1 (de) * | 1987-07-16 | 1989-01-26 | Schering Ag | 11(beta)-phenyl-4,9,15-estratriene, deren herstellung und diese enthaltende pharmazeutische praeparate |
FR2618783B1 (fr) * | 1987-07-30 | 1991-02-01 | Roussel Uclaf | Nouveaux 17-aryle steroides, leurs procedes et des intermediaires de preparation comme medicaments et les compositions pharmaceutiques les renfermant |
FR2620707B1 (fr) * | 1987-09-18 | 1989-12-08 | Roussel Uclaf | Nouveaux steroides comportant un cycle spirannique a 3, 4 ou 6 chainons en position 17, leur procede et des intermediaires de preparation, leur application comme medicaments et les compositions pharmaceutiques les renfermant |
EP0321010B1 (en) * | 1987-12-12 | 1993-02-03 | Akzo N.V. | New 11-arylsteroid compounds |
US4954490A (en) * | 1988-06-23 | 1990-09-04 | Research Triangle Institute | 11 β-substituted progesterone analogs |
-
1990
- 1990-08-06 JP JP51117490A patent/JP3202224B2/ja not_active Expired - Fee Related
- 1990-08-06 WO PCT/DE1990/000614 patent/WO1991001958A2/de unknown
- 1990-08-06 DE DE59010853T patent/DE59010853D1/de not_active Expired - Fee Related
- 1990-08-06 DK DK90250199T patent/DK0411733T3/da active
- 1990-08-06 EP EP90250199A patent/EP0411733B1/de not_active Expired - Lifetime
- 1990-08-06 ES ES90250199T patent/ES2127181T3/es not_active Expired - Lifetime
- 1990-08-06 AT AT90250199T patent/ATE172469T1/de not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
WO1991001958A3 (de) | 1991-12-12 |
EP0411733B1 (de) | 1998-10-21 |
JPH05504759A (ja) | 1993-07-22 |
ES2127181T3 (es) | 1999-04-16 |
WO1991001958A2 (de) | 1991-02-21 |
ATE172469T1 (de) | 1998-11-15 |
DE59010853D1 (de) | 1998-12-03 |
EP0411733A2 (de) | 1991-02-06 |
JP3202224B2 (ja) | 2001-08-27 |
EP0411733A3 (en) | 1992-01-22 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
ES2127181T3 (es) | 11-beta-aril-gona-4,9-dien-3-onas. | |
FI921087A0 (fi) | Nya estrar av tienylkarboxylsyror och aminoalkoholer, deras kvaterniseringsprodukter och framstaellning och anvaendning av naemnda foereningar. | |
FI902911A0 (fi) | Cigarettpapper i flere lager foer att reducera bistroems roek. | |
DK172089D0 (da) | 1,3-dioxolanderivater samt fremgangsmaade til fremstilling deraf | |
FR2654223B1 (fr) | Protection d'objectif. | |
DE68923797D1 (de) | Skalpell. | |
DE3870959D1 (de) | 2-difluormethoxy-1,1,1,2-tetrafluoraethan als anaesthetikum. | |
IT1228288B (it) | Composti ad attivita' antiserotoninica | |
FI852610A0 (fi) | Dihydropyridiner innehaollande fasta laekemedelsprodukter och foerfarande foer deras framstaellning. | |
IT1184730B (it) | Procedimento per produrre difenilammine oppure n,n'-difenil-fenilendiammine | |
IT1212143B (it) | Composizione ad attivita'tricogena. | |
FI881609A (fi) | Dihydropyridinamider, foerfarande foer deras framstaellning och deras anvaendning i laekemedel. | |
IT1216560B (it) | Procedimento per la preparazione di bis(2,2,6,6_tetrametil_4_piperidil)ammina. | |
PT87563A (pt) | Process for the preparation of vinylcephalosporins useful as medicaments | |
EP0401262A4 (en) | 24r-scymnol, and preparation and use thereof | |
LV10870A (lv) | Jauni fosfolipidu atvasinajumi | |
FR2593066B1 (fr) | Compositions therapeutiques a base de derives de 3-alkoxyflavones et nouveaux derives de 3-alkoxyflavones. | |
ES2073495T3 (es) | Benzotiazepinas. | |
DK0552631T3 (da) | Alfa-Aryl-alfa-hydroxy-beta-imidazolinyl-propionsyreamider | |
NO894037L (no) | Fremgangsmaate for fremstilling av nye 2-metoksykarbonyl-substituerte n,n'-di(trimetoksybenzoyl) piperaziner. | |
DE3878988D1 (de) | 1,2-di(4-isobutylphenyl)aethylen, dessen herstellung und verwendung als zwischenprodukt. | |
ES8800666A1 (es) | Procedimiento para la obtencion de derivados de 1,4-dihidropiridina | |
IT1197892B (it) | Composizioni farmaceutiche ad attivita' cicatrizzante | |
IT8820273A0 (it) | Procedimento di preparazione della n,n'_bis_(2_idrossietil)_piperazina . | |
IT8621852A0 (it) | 4-cloro-arilossi-acetil-e 4-cloro-arilossi-propionil-malonati aventi proprieta' erbicide. |