FR2522328B1 - Nouveaux produits derives de la structure 3-ceto 4,9 19-nor steroides, leur procede de preparation et leur application comme medicaments - Google Patents
Nouveaux produits derives de la structure 3-ceto 4,9 19-nor steroides, leur procede de preparation et leur application comme medicamentsInfo
- Publication number
- FR2522328B1 FR2522328B1 FR8203338A FR8203338A FR2522328B1 FR 2522328 B1 FR2522328 B1 FR 2522328B1 FR 8203338 A FR8203338 A FR 8203338A FR 8203338 A FR8203338 A FR 8203338A FR 2522328 B1 FR2522328 B1 FR 2522328B1
- Authority
- FR
- France
- Prior art keywords
- ceto
- steroids
- medicaments
- application
- preparation process
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J61/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton has been modified by contraction of only one ring by one or two atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
- C07J1/0051—Estrane derivatives
- C07J1/0081—Substituted in position 17 alfa and 17 beta
- C07J1/0088—Substituted in position 17 alfa and 17 beta the substituent in position 17 alfa being an unsaturated hydrocarbon group
- C07J1/0096—Alkynyl derivatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/38—Drugs for disorders of the endocrine system of the suprarenal hormones
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J17/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, having an oxygen-containing hetero ring not condensed with the cyclopenta(a)hydrophenanthrene skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J21/00—Normal steroids containing carbon, hydrogen, halogen or oxygen having an oxygen-containing hetero ring spiro-condensed with the cyclopenta(a)hydrophenanthrene skeleton
- C07J21/005—Ketals
- C07J21/006—Ketals at position 3
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J31/00—Normal steroids containing one or more sulfur atoms not belonging to a hetero ring
- C07J31/006—Normal steroids containing one or more sulfur atoms not belonging to a hetero ring not covered by C07J31/003
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J33/00—Normal steroids having a sulfur-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton
- C07J33/002—Normal steroids having a sulfur-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton not condensed
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
- C07J41/0005—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring the nitrogen atom being directly linked to the cyclopenta(a)hydro phenanthrene skeleton
- C07J41/0016—Oximes
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
- C07J41/0033—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005
- C07J41/0077—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 substituted in position 11-beta by a carbon atom, further substituted by a group comprising at least one further carbon atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
- C07J41/0033—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005
- C07J41/0077—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 substituted in position 11-beta by a carbon atom, further substituted by a group comprising at least one further carbon atom
- C07J41/0083—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 substituted in position 11-beta by a carbon atom, further substituted by a group comprising at least one further carbon atom substituted in position 11-beta by an optionally substituted phenyl group not further condensed with other rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
- C07J41/0033—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005
- C07J41/0094—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 containing nitrile radicals, including thiocyanide radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J51/00—Normal steroids with unmodified cyclopenta(a)hydrophenanthrene skeleton not provided for in groups C07J1/00 - C07J43/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J7/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms
- C07J7/0005—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21
- C07J7/001—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21 substituted in position 20 by a keto group
- C07J7/0015—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21 substituted in position 20 by a keto group not substituted in position 17 alfa
- C07J7/0025—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21 substituted in position 20 by a keto group not substituted in position 17 alfa substituted in position 16
- C07J7/003—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21 substituted in position 20 by a keto group not substituted in position 17 alfa substituted in position 16 by a saturated or unsaturated hydrocarbon group
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J7/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms
- C07J7/0005—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21
- C07J7/001—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21 substituted in position 20 by a keto group
- C07J7/004—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21 substituted in position 20 by a keto group substituted in position 17 alfa
- C07J7/0045—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21 substituted in position 20 by a keto group substituted in position 17 alfa not substituted in position 16
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J7/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms
- C07J7/0005—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21
- C07J7/0065—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21 substituted in position 20 by an OH group free esterified or etherified
- C07J7/0075—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21 substituted in position 20 by an OH group free esterified or etherified substituted in position 17 alfa
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J71/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
- C07J71/0005—Oxygen-containing hetero ring
- C07J71/001—Oxiranes
Priority Applications (39)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR8203338A FR2522328B1 (fr) | 1982-03-01 | 1982-03-01 | Nouveaux produits derives de la structure 3-ceto 4,9 19-nor steroides, leur procede de preparation et leur application comme medicaments |
SE8300308A SE8300308L (sv) | 1982-03-01 | 1983-01-21 | Nya 3-keto- 4,9,19-nor-stereoider, deras framstellning, deras anvendning som lekemedel, kompositioner innehallande dem och deras nya erhallna mellanprodukter |
MA19934A MA19716A1 (fr) | 1982-03-01 | 1983-02-11 | Procede de preparation de nouveaux derives 3- ceto a 4,9 19- norsteroides . |
ZA83982A ZA83982B (en) | 1982-03-01 | 1983-02-14 | 3-ceto delta 4,9 19-nor steroid derivatives,their preparation their use as medicaments,the compositions containing them and the intermediates thus obtained |
IL67920A IL67920A0 (en) | 1982-03-01 | 1983-02-15 | New derivatives of 3-keto delta 4,9,19-nor steroids,their preparation,their application as medicaments,the compositions containing them and the new intermediates obtained |
US06/469,042 US4477445A (en) | 1982-03-01 | 1983-02-23 | 3-Keto-19-nor-Δ4,9-steroids |
PH28558A PH21308A (en) | 1982-03-01 | 1983-02-23 | 3-keto-19-nor-/4,9-steroids |
GR70610A GR78465B (fr) | 1982-03-01 | 1983-02-25 | |
DK89783A DK89783A (da) | 1982-03-01 | 1983-02-25 | Fremgangsmaade til fremstilling af 3-keto-delta4,9-19-nor-steroidderivater |
PCT/FR1983/000034 WO1983003099A1 (fr) | 1982-03-01 | 1983-02-25 | 3-ceto-delta 4,9-19-norsteroides |
EG133/83A EG15881A (en) | 1982-03-01 | 1983-02-27 | Process for preparing of new products of 3-aceto delta 4,9,19 steroids |
CH1099/83A CH657368A5 (fr) | 1982-03-01 | 1983-02-28 | Derives de 3-ceto delta-4,9 19-nor-steroides, leur preparation, les compositions les renfermant et les produits de depart pour leur preparation. |
CA000422503A CA1206471A (fr) | 1982-03-01 | 1983-02-28 | Procede de preparation de nouveaux derives 3-ceto .delta.4,9 19-nor steroides |
YU00478/83A YU47883A (en) | 1982-03-01 | 1983-02-28 | Process for obtaining new 3-keto-delta-4,9,19-nor steroid derivatives |
MX8310507U MX7199E (es) | 1982-03-01 | 1983-02-28 | Procedimiento para preparar derivados de 3-cetodelta-4,9,19-nor-esteroides |
AU11913/83A AU562739B2 (en) | 1982-03-01 | 1983-02-28 | 3 keto delta4,9,19-nor steroid derivatives |
IT47820/83A IT1197592B (it) | 1982-03-01 | 1983-02-28 | Derivati di 3-cheto delta 4,9 19-nor-steroidi,procedimento per la loro preparazione,loro impiego come medicamenti,composizioni che li contengono ed intermedi ottenuti |
PT76307A PT76307B (fr) | 1982-03-01 | 1983-02-28 | Procede de preparation de nouveaux derives 3-ceto delta 4,9 19-nor steroides |
BE0/210223A BE896042A (fr) | 1982-03-01 | 1983-02-28 | Nouveaux derives de 3-ceto delta 4,9, 19-nor-steroides, leur preparation, leur application comme medicaments, les compositions les renfermant et les nouveaux intermediaires obtenus |
SU833561503A SU1340593A3 (ru) | 1982-03-01 | 1983-02-28 | Способ получени производных @ @ 19-норстероидов |
NL8300738A NL8300738A (nl) | 1982-03-01 | 1983-02-28 | Nieuwe derivaten van 3-keto-delta4.9-19-nor-steroiden, de bereiding daarvan, de toepassing daarvan als geneesmiddelen, de preparaten, die deze verbindingen bevatten, en de verkregen nieuwe intermediairen. |
FI830652A FI80049C (fi) | 1982-03-01 | 1983-02-28 | Foerfarande foer framstaellning av terapeutiskt anvaendbara 19-nor-/ 4,9-steroider. |
LU84667A LU84667A1 (fr) | 1982-03-01 | 1983-02-28 | Nouveaux derives de 3-ceto delta 4,9 19-nor-steroides,leur preparation,leur application comme medicament,les compositions les reinfermant et les nouveaux intermediaires obtenus |
KR1019830000853A KR880001870B1 (ko) | 1982-03-01 | 1983-02-28 | 3-케토 △ 4,9,19-노르 스테로이드 유도체의 제조방법 |
GB08305558A GB2118186B (en) | 1982-03-01 | 1983-03-01 | 11-substituted steroid 4,9-dienes and 4-ene-9,10-epoxides |
DE19833307143 DE3307143A1 (de) | 1982-03-01 | 1983-03-01 | Neue derivate der 3-keto-(delta)-4,9,19-nor-steroide, deren herstellung, deren verwendung als arzneimittel, die diese enthaltenden zusammensetzungen und erhaltene neue zwischenprodukte |
IE429/83A IE54748B1 (en) | 1982-03-01 | 1983-03-01 | Steroid compounds |
ES520195A ES8401495A1 (es) | 1982-03-01 | 1983-03-01 | Procedimiento para preparar nuevos derivados de 3-ceto- 4,9,19-nor-esteroides. |
JP58031909A JPS58201800A (ja) | 1982-03-01 | 1983-03-01 | 3―ケト―δ↑4‖↑9―19―ノルステロイドの新誘導体、それらの製造法及びそれらを含む製薬組成物 |
HU83690A HU193269B (en) | 1982-03-01 | 1983-03-01 | Process for preparing 3-oxo-delta up 4,9 - and 3-oxo-delta up 4-9,11-epoxy-19-norsteroids |
AR83292260A AR241187A1 (es) | 1982-03-01 | 1983-03-01 | Procedimiento para la preparacion de nuevos productos derivados de la estructura 3-ceto delta-4,9-19-nor esteroides e intermediarios para uso exclusivo en dicho procedimiento. |
AT0071183A AT396109B (de) | 1982-03-01 | 1983-03-01 | Verfahren zur herstellung neuer 3-keto-delta 4,9,19-norsteroid-derivate |
OA58138A OA07567A (fr) | 1982-03-01 | 1983-10-13 | 3-céto-delta 4,9-19-norstéroides. |
US06/618,590 US4540686A (en) | 1982-03-01 | 1984-06-08 | 3-Keto-19-nor-Δ4,9 -steroids |
CA000486788A CA1215353A (fr) | 1982-03-01 | 1985-07-15 | PROCEDE POUR LA PREPARATION DE DERIVES DE 3-CETO 5.alpha.- HYDROXY .DELTA.9 19-NORSTEROIDES ET LES DERIVES AINSI OBTENUS |
FR888814868A FR2639045B2 (fr) | 1982-03-01 | 1988-11-16 | Nouveaux produits derives de la structure 3-ceto-delta-4,9-19-nor steroides et leur application comme medicaments |
US07/438,359 US5064822A (en) | 1982-03-01 | 1989-11-16 | Novel 3-keto-19-nor-Δ4,9 -steroids |
JP2046023A JPH02275895A (ja) | 1982-03-01 | 1990-02-28 | 3―ケト―△↑9―19―ノルステロイドの新誘導体 |
US07/757,261 US5182381A (en) | 1982-03-01 | 1991-09-10 | Intermediates for 3-keto-19-nor-Δ4,9 -steroids |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR8203338A FR2522328B1 (fr) | 1982-03-01 | 1982-03-01 | Nouveaux produits derives de la structure 3-ceto 4,9 19-nor steroides, leur procede de preparation et leur application comme medicaments |
Publications (2)
Publication Number | Publication Date |
---|---|
FR2522328A1 FR2522328A1 (fr) | 1983-09-02 |
FR2522328B1 true FR2522328B1 (fr) | 1986-02-14 |
Family
ID=9271439
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
FR8203338A Expired FR2522328B1 (fr) | 1982-03-01 | 1982-03-01 | Nouveaux produits derives de la structure 3-ceto 4,9 19-nor steroides, leur procede de preparation et leur application comme medicaments |
Country Status (32)
Country | Link |
---|---|
US (2) | US4477445A (fr) |
JP (2) | JPS58201800A (fr) |
KR (1) | KR880001870B1 (fr) |
AR (1) | AR241187A1 (fr) |
AT (1) | AT396109B (fr) |
AU (1) | AU562739B2 (fr) |
BE (1) | BE896042A (fr) |
CA (1) | CA1206471A (fr) |
CH (1) | CH657368A5 (fr) |
DE (1) | DE3307143A1 (fr) |
DK (1) | DK89783A (fr) |
EG (1) | EG15881A (fr) |
ES (1) | ES8401495A1 (fr) |
FI (1) | FI80049C (fr) |
FR (1) | FR2522328B1 (fr) |
GB (1) | GB2118186B (fr) |
GR (1) | GR78465B (fr) |
HU (1) | HU193269B (fr) |
IE (1) | IE54748B1 (fr) |
IL (1) | IL67920A0 (fr) |
IT (1) | IT1197592B (fr) |
LU (1) | LU84667A1 (fr) |
MA (1) | MA19716A1 (fr) |
MX (1) | MX7199E (fr) |
NL (1) | NL8300738A (fr) |
PH (1) | PH21308A (fr) |
PT (1) | PT76307B (fr) |
SE (1) | SE8300308L (fr) |
SU (1) | SU1340593A3 (fr) |
WO (1) | WO1983003099A1 (fr) |
YU (1) | YU47883A (fr) |
ZA (1) | ZA83982B (fr) |
Families Citing this family (77)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2528434B1 (fr) * | 1982-06-11 | 1985-07-19 | Roussel Uclaf | Nouveaux 19-nor steroides substitues en 11b et eventuellement en 2, leur procede de preparation et leur application comme medicament |
US5182381A (en) * | 1982-03-01 | 1993-01-26 | Roussel Ulcaf | Intermediates for 3-keto-19-nor-Δ4,9 -steroids |
FR2639045B2 (fr) * | 1982-03-01 | 1994-07-29 | Roussel Uclaf | Nouveaux produits derives de la structure 3-ceto-delta-4,9-19-nor steroides et leur application comme medicaments |
DE3231827A1 (de) * | 1982-08-24 | 1984-03-01 | Schering AG, 1000 Berlin und 4709 Bergkamen | 11ss-aryl-17(alpha)-alkinyl-17ss-hydroxy-4,9(10)- estradien-3-on-derivate, deren herstellung und diese enthaltende pharmazeutische praeparate |
DE3461090D1 (en) * | 1983-02-18 | 1986-12-04 | Schering Ag | 11-beta-aryl-estradienes, process for their preparation and pharmaceutical compositions containing them |
IT1212835B (it) * | 1983-08-18 | 1989-11-30 | Lehner Ag | Derivati di acidi biliari, procedimento per la loro preparazione e relative composizioni farmaceutiche. |
DE3347126A1 (de) * | 1983-12-22 | 1985-07-11 | Schering AG, 1000 Berlin und 4709 Bergkamen | 11ss-aryl-estradiene, deren herstellung und diese enthaltende pharmazeutische praeparate |
US4666898A (en) * | 1983-12-28 | 1987-05-19 | Jackson Lab. | Treatment of obesity, diabetes and other symptoms of hypercorticoidism using etiocholanolones |
DE3410880A1 (de) * | 1984-03-21 | 1985-10-03 | Schering AG, Berlin und Bergkamen, 1000 Berlin | 17-substituierte estradiene und estratriene |
DE3438500C1 (de) * | 1984-10-18 | 1986-05-28 | Schering AG, 1000 Berlin und 4709 Bergkamen | Verfahren zur Herstellung 11ß-substituierter Δ↑9↑-19-Norsteroide |
FR2573657B1 (fr) * | 1984-11-29 | 1989-05-12 | Roussel Uclaf | Produit comprenant une substance antiprogestomimetique et une substance uterotonique |
FR2576025B1 (fr) * | 1985-01-14 | 1987-01-23 | Roussel Uclaf | Nouveaux steroides substitues en position 10, leur procede et les intermediaires de preparation, leur application comme medicaments, les compositions pharmaceutiques les contenant |
AU580843B2 (en) * | 1985-02-07 | 1989-02-02 | Schering Aktiengesellschaft | 11``-phenyl-gonanes, their manufacture and pharmaceutical preparations containing them |
CA1241947A (fr) * | 1985-05-31 | 1988-09-13 | Pierre R. Proulx | Derives de sterol-polyene pour sondes de membranes |
GB8513723D0 (en) * | 1985-05-31 | 1985-07-03 | Erba Farmitalia | 11-beta substituted steroids |
US4686214A (en) * | 1985-10-30 | 1987-08-11 | Alcon Laboratories, Inc. | Anti-inflammatory compounds for ophthalmic use |
FR2598421B1 (fr) * | 1986-05-06 | 1988-08-19 | Roussel Uclaf | Nouveaux produits 19-nor ou 19-nor d-homo steroides substitues en position 11b par un radical phenyle portant un radical alkynyle, leur procede de preparation, leur application comme medicaments et les compositions les renfermant |
DE3625315A1 (de) * | 1986-07-25 | 1988-01-28 | Schering Ag | 11ss-(4-isopropenylphenyl)-estra-4,9-diene, deren herstellung und diese enthaltende pharmazeutische praeparate |
US4774236A (en) * | 1986-09-17 | 1988-09-27 | Research Triangle Institute | 17α-(substituted-methyl)-17β-hydroxy/esterified hydroxy steroids and pharmaceutical compositions containing them |
US5272140A (en) * | 1987-01-23 | 1993-12-21 | Akzo N.V. | 11-aryl steroid derivatives |
FR2610933B1 (fr) * | 1987-02-18 | 1989-06-09 | Roussel Uclaf | Nouveaux 19-nor steroides substitues en position 7, leur preparation, leur application comme medicaments, les compositions pharmaceutiques les renfermant |
US5446178A (en) * | 1987-03-18 | 1995-08-29 | Schering Aktiengesellschaft | Process for preparing 19,11β-bridged steroids |
DE3708942A1 (de) * | 1987-03-18 | 1988-09-29 | Schering Ag | 19,11ss-ueberbrueckte steroide, deren herstellung und diese enthaltende pharmazeutische praeparate |
US5075464A (en) * | 1987-04-22 | 1991-12-24 | Merrell Dow Pharmaceuticals Inc. | 17β-(cyclopropylamino)androstene derivatives |
DE3723788A1 (de) * | 1987-07-16 | 1989-01-26 | Schering Ag | 11(beta)-phenyl-4,9,15-estratriene, deren herstellung und diese enthaltende pharmazeutische praeparate |
FR2618783B1 (fr) * | 1987-07-30 | 1991-02-01 | Roussel Uclaf | Nouveaux 17-aryle steroides, leurs procedes et des intermediaires de preparation comme medicaments et les compositions pharmaceutiques les renfermant |
FR2620707B1 (fr) * | 1987-09-18 | 1989-12-08 | Roussel Uclaf | Nouveaux steroides comportant un cycle spirannique a 3, 4 ou 6 chainons en position 17, leur procede et des intermediaires de preparation, leur application comme medicaments et les compositions pharmaceutiques les renfermant |
US4954490A (en) * | 1988-06-23 | 1990-09-04 | Research Triangle Institute | 11 β-substituted progesterone analogs |
DE3822770A1 (de) * | 1988-07-01 | 1990-01-04 | Schering Ag | 13-alkyl-11ss-phenylgonane |
EP0369881A1 (fr) * | 1988-11-16 | 1990-05-23 | Roussel-Uclaf | Nouveaux produits dérivés de la structure 3-céto delta-4,9 19-nor stéroides et leur application comme médicaments |
FR2643638B1 (fr) * | 1989-02-24 | 1991-06-14 | Roussel Uclaf | Nouveaux 19-nor steroides ayant en position 11beta une chaine carbonee comportant une fonction amide ou carbamate, leur procede de preparation et les intermediaires de ce procede, leur application comme medicaments et les compositions pharmaceutiques les contenant |
US6790971B1 (en) * | 1989-02-24 | 2004-09-14 | Aventis Pharma S.A. | 19-Nor-steroids |
FR2665901B2 (fr) * | 1989-02-24 | 1994-07-29 | Roussel Uclaf | Nouveaux 19-nor sterouides ayant en position 11beta une chaine carbonee comportant une fonction amide, leur preparation, leur application comme medicaments. |
EP0411733B1 (fr) * | 1989-08-04 | 1998-10-21 | Schering Aktiengesellschaft | 11-Bêta-aryl-gona-4,9-diène-3-ones |
US5276023A (en) * | 1989-08-08 | 1994-01-04 | Roussel Uclaf | 19-nor-steroid esters |
FR2651435A1 (fr) * | 1989-09-07 | 1991-03-08 | Roussel Uclaf | Nouvelle utilisation de composes anti-progestomimetiques. |
FR2659233B1 (fr) * | 1990-03-06 | 1994-01-21 | Roussel Uclaf | Nouvelle utilisation de composes anti-progestomimetiques chez les animaux d'elevage. |
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CH571537A5 (fr) * | 1970-04-24 | 1976-01-15 | Sandoz Ag | |
CH558346A (de) * | 1971-06-17 | 1975-01-31 | Sandoz Ag | Verfahren zur herstellung neuer 3-oximino-17(alpha)-propadienyl-substituierter steroide. |
BE787898A (fr) * | 1971-08-26 | 1973-02-23 | Roussel Uclaf | Nouveaux composes steroides trieniques et procede de preparation |
DE2636405C2 (de) * | 1976-08-12 | 1982-07-08 | Schering Ag, 1000 Berlin Und 4619 Bergkamen | Δ↑1↑↑5↑-17α-Chloräthinyl- und -Propinylsteroide der Östranreihe, Verfahren zu ihrer Herstellung sowie diese enthaltende pharmazeutische Präparate |
FR2377417A1 (fr) * | 1977-01-13 | 1978-08-11 | Roussel Uclaf | Nouveaux derives steroides substitues en 11b, ainsi que leur procede de preparation |
FR2377419A1 (fr) * | 1977-01-13 | 1978-08-11 | Roussel Uclaf | Nouveaux derives steroides 11b-substitues 1,3,5 (10) trieniques, leur procede de preparation et leur application comme medicament |
FR2377418A1 (fr) * | 1977-01-13 | 1978-08-11 | Roussel Uclaf | Nouveaux derives steroides 4,9-dieniques 11b-substitues, leur procede de preparation et leur application comme medicaments |
FR2495621A1 (fr) * | 1980-12-05 | 1982-06-11 | Roussel Uclaf | Nouveaux derives de l'estra 4,9-diene, leur procede de preparation et leur application comme medicaments |
ZA8231B (en) * | 1981-01-09 | 1982-11-24 | Roussel Uclaf | New 11 -substituted steroid derivatives, their preparation, their use as medicaments, the compositions containing them and the new intermediates thus obtained |
-
1982
- 1982-03-01 FR FR8203338A patent/FR2522328B1/fr not_active Expired
-
1983
- 1983-01-21 SE SE8300308A patent/SE8300308L/ unknown
- 1983-02-11 MA MA19934A patent/MA19716A1/fr unknown
- 1983-02-14 ZA ZA83982A patent/ZA83982B/xx unknown
- 1983-02-15 IL IL67920A patent/IL67920A0/xx not_active IP Right Cessation
- 1983-02-23 PH PH28558A patent/PH21308A/en unknown
- 1983-02-23 US US06/469,042 patent/US4477445A/en not_active Expired - Fee Related
- 1983-02-25 DK DK89783A patent/DK89783A/da not_active Application Discontinuation
- 1983-02-25 GR GR70610A patent/GR78465B/el unknown
- 1983-02-25 WO PCT/FR1983/000034 patent/WO1983003099A1/fr unknown
- 1983-02-27 EG EG133/83A patent/EG15881A/xx active
- 1983-02-28 PT PT76307A patent/PT76307B/fr not_active IP Right Cessation
- 1983-02-28 NL NL8300738A patent/NL8300738A/nl not_active Application Discontinuation
- 1983-02-28 FI FI830652A patent/FI80049C/fi not_active IP Right Cessation
- 1983-02-28 SU SU833561503A patent/SU1340593A3/ru active
- 1983-02-28 LU LU84667A patent/LU84667A1/fr unknown
- 1983-02-28 IT IT47820/83A patent/IT1197592B/it active
- 1983-02-28 AU AU11913/83A patent/AU562739B2/en not_active Ceased
- 1983-02-28 BE BE0/210223A patent/BE896042A/fr not_active IP Right Cessation
- 1983-02-28 MX MX8310507U patent/MX7199E/es unknown
- 1983-02-28 KR KR1019830000853A patent/KR880001870B1/ko not_active IP Right Cessation
- 1983-02-28 YU YU00478/83A patent/YU47883A/xx unknown
- 1983-02-28 CA CA000422503A patent/CA1206471A/fr not_active Expired
- 1983-02-28 CH CH1099/83A patent/CH657368A5/fr unknown
- 1983-03-01 JP JP58031909A patent/JPS58201800A/ja active Granted
- 1983-03-01 AT AT0071183A patent/AT396109B/de not_active IP Right Cessation
- 1983-03-01 IE IE429/83A patent/IE54748B1/en not_active IP Right Cessation
- 1983-03-01 DE DE19833307143 patent/DE3307143A1/de not_active Withdrawn
- 1983-03-01 HU HU83690A patent/HU193269B/hu not_active IP Right Cessation
- 1983-03-01 GB GB08305558A patent/GB2118186B/en not_active Expired
- 1983-03-01 AR AR83292260A patent/AR241187A1/es active
- 1983-03-01 ES ES520195A patent/ES8401495A1/es not_active Expired
-
1984
- 1984-06-08 US US06/618,590 patent/US4540686A/en not_active Expired - Fee Related
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1990
- 1990-02-28 JP JP2046023A patent/JPH02275895A/ja active Granted
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