ATE227711T1 - Kodaistatine a,b,c und d, verfahren zur herstellung und verwendung - Google Patents

Kodaistatine a,b,c und d, verfahren zur herstellung und verwendung

Info

Publication number
ATE227711T1
ATE227711T1 AT98924129T AT98924129T ATE227711T1 AT E227711 T1 ATE227711 T1 AT E227711T1 AT 98924129 T AT98924129 T AT 98924129T AT 98924129 T AT98924129 T AT 98924129T AT E227711 T1 ATE227711 T1 AT E227711T1
Authority
AT
Austria
Prior art keywords
kodaistatines
preparation
Prior art date
Application number
AT98924129T
Other languages
English (en)
Inventor
Nirogi Venkata Sat Ramakrishna
Keshavapura Hosamane Sre Swamy
Erra Koteswara Sat Vijayakumar
Suresh Rudra Nadkarni
Kenia Jayvanti
Andreas W Herling
Herbert Kogler
Laszlo Vertesy
Rajan Mukund Panshikar
Cross Lane Dindayal
Kota K S R Murthy Sridevi
Mythili Raman
Roda Maneck Dalal
Original Assignee
Aventis Pharma Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Aventis Pharma Gmbh filed Critical Aventis Pharma Gmbh
Application granted granted Critical
Publication of ATE227711T1 publication Critical patent/ATE227711T1/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00Preparation of oxygen-containing organic compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D307/00Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/34Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D307/56Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D307/60Two oxygen atoms, e.g. succinic anhydride
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/02Separating microorganisms from their culture media

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Medicinal Chemistry (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Diabetes (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Virology (AREA)
  • Epidemiology (AREA)
  • Biomedical Technology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Emergency Medicine (AREA)
  • Endocrinology (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Compounds Of Unknown Constitution (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
AT98924129T 1997-04-18 1998-04-17 Kodaistatine a,b,c und d, verfahren zur herstellung und verwendung ATE227711T1 (de)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
EP97106453 1997-04-18
EP97109900 1997-06-18
EP97120536 1997-11-24
PCT/EP1998/002247 WO1998047888A1 (en) 1997-04-18 1998-04-17 Kodaistatins a, b, c and d, a process for their production and their use

Publications (1)

Publication Number Publication Date
ATE227711T1 true ATE227711T1 (de) 2002-11-15

Family

ID=27238189

Family Applications (1)

Application Number Title Priority Date Filing Date
AT98924129T ATE227711T1 (de) 1997-04-18 1998-04-17 Kodaistatine a,b,c und d, verfahren zur herstellung und verwendung

Country Status (14)

Country Link
US (1) US6166070A (de)
EP (1) EP0973760B1 (de)
JP (1) JP3993643B2 (de)
CN (1) CN1252797A (de)
AR (1) AR012449A1 (de)
AT (1) ATE227711T1 (de)
AU (1) AU736137B2 (de)
BR (1) BR9809104A (de)
CA (1) CA2286822C (de)
DE (1) DE69809405T2 (de)
DK (1) DK0973760T3 (de)
ES (1) ES2186164T3 (de)
PT (1) PT973760E (de)
WO (1) WO1998047888A1 (de)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EE200200216A (et) 1999-10-25 2003-06-16 Aventis Pharma Deutschland Gmbh Aromaatsed diketoderivaadid, nende valmistamismeetodid ja farmatseutiline kompositsioon
CN108929293B (zh) * 2017-05-25 2021-08-13 上海交通大学医学院附属仁济医院 丁烯酸内酯类化合物的制备方法和用途

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TW399041B (en) * 1992-09-09 2000-07-21 Hoechst Ag Substituted cyclohexane derivatives, the preparation and the use for treating diseases
TW255880B (de) * 1992-09-09 1995-09-01 Hoechst Ag
JPH09202797A (ja) * 1996-01-24 1997-08-05 Sankyo Co Ltd 5α−還元酵素阻害化合物d1067331

Also Published As

Publication number Publication date
CA2286822C (en) 2008-07-29
DK0973760T3 (da) 2003-03-03
JP2001524092A (ja) 2001-11-27
AR012449A1 (es) 2000-10-18
EP0973760B1 (de) 2002-11-13
AU736137B2 (en) 2001-07-26
PT973760E (pt) 2003-03-31
AU7644298A (en) 1998-11-13
DE69809405D1 (de) 2002-12-19
BR9809104A (pt) 2000-08-01
CA2286822A1 (en) 1998-10-29
JP3993643B2 (ja) 2007-10-17
ES2186164T3 (es) 2003-05-01
CN1252797A (zh) 2000-05-10
US6166070A (en) 2000-12-26
WO1998047888A1 (en) 1998-10-29
EP0973760A1 (de) 2000-01-26
DE69809405T2 (de) 2003-07-10

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