DE69809405D1 - Kodaistatine a,b,c und d, verfahren zur herstellung und verwendung - Google Patents

Kodaistatine a,b,c und d, verfahren zur herstellung und verwendung

Info

Publication number
DE69809405D1
DE69809405D1 DE69809405T DE69809405T DE69809405D1 DE 69809405 D1 DE69809405 D1 DE 69809405D1 DE 69809405 T DE69809405 T DE 69809405T DE 69809405 T DE69809405 T DE 69809405T DE 69809405 D1 DE69809405 D1 DE 69809405D1
Authority
DE
Germany
Prior art keywords
kodaistatine
production
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69809405T
Other languages
English (en)
Other versions
DE69809405T2 (de
Inventor
Nirogi Venkata Sat Ramakrishna
Keshavapura Hosamane Sre Swamy
Erra Koteswara Sat Vijayakumar
Suresh Rudra Nadkarni
Kenia Jayvanti
W Herling
Herbert Kogler
Laszlo Vertesy
Rajan Mukund Panshikar
Kota Sridevi
Mythili Raman
Roda Maneck Dalal
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sanofi Aventis Deutschland GmbH
Original Assignee
Aventis Pharma Deutschland GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Aventis Pharma Deutschland GmbH filed Critical Aventis Pharma Deutschland GmbH
Application granted granted Critical
Publication of DE69809405D1 publication Critical patent/DE69809405D1/de
Publication of DE69809405T2 publication Critical patent/DE69809405T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D307/56—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D307/60—Two oxygen atoms, e.g. succinic anhydride
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/02—Separating microorganisms from their culture media

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Diabetes (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Epidemiology (AREA)
  • Biomedical Technology (AREA)
  • Virology (AREA)
  • Emergency Medicine (AREA)
  • Endocrinology (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
  • Compounds Of Unknown Constitution (AREA)
DE69809405T 1997-04-18 1998-04-17 Kodaistatine a,b,c und d, verfahren zur herstellung und verwendung Expired - Lifetime DE69809405T2 (de)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
EP97106453 1997-04-18
EP97109900 1997-06-18
EP97120536 1997-11-24
PCT/EP1998/002247 WO1998047888A1 (en) 1997-04-18 1998-04-17 Kodaistatins a, b, c and d, a process for their production and their use

Publications (2)

Publication Number Publication Date
DE69809405D1 true DE69809405D1 (de) 2002-12-19
DE69809405T2 DE69809405T2 (de) 2003-07-10

Family

ID=27238189

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69809405T Expired - Lifetime DE69809405T2 (de) 1997-04-18 1998-04-17 Kodaistatine a,b,c und d, verfahren zur herstellung und verwendung

Country Status (14)

Country Link
US (1) US6166070A (de)
EP (1) EP0973760B1 (de)
JP (1) JP3993643B2 (de)
CN (1) CN1252797A (de)
AR (1) AR012449A1 (de)
AT (1) ATE227711T1 (de)
AU (1) AU736137B2 (de)
BR (1) BR9809104A (de)
CA (1) CA2286822C (de)
DE (1) DE69809405T2 (de)
DK (1) DK0973760T3 (de)
ES (1) ES2186164T3 (de)
PT (1) PT973760E (de)
WO (1) WO1998047888A1 (de)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HUP0203129A3 (en) 1999-10-25 2003-12-29 Sanofi Aventis Deutschland Aromatic di-keto derivatives, process for producing them and use them as pharmaceuticals
CN108929293B (zh) * 2017-05-25 2021-08-13 上海交通大学医学院附属仁济医院 丁烯酸内酯类化合物的制备方法和用途

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TW255880B (de) * 1992-09-09 1995-09-01 Hoechst Ag
TW399041B (en) * 1992-09-09 2000-07-21 Hoechst Ag Substituted cyclohexane derivatives, the preparation and the use for treating diseases
JPH09202797A (ja) * 1996-01-24 1997-08-05 Sankyo Co Ltd ５α−還元酵素阻害化合物ｄ１０６７３３１

Also Published As

Publication number Publication date
CN1252797A (zh) 2000-05-10
BR9809104A (pt) 2000-08-01
US6166070A (en) 2000-12-26
CA2286822C (en) 2008-07-29
AU7644298A (en) 1998-11-13
ES2186164T3 (es) 2003-05-01
ATE227711T1 (de) 2002-11-15
EP0973760A1 (de) 2000-01-26
DE69809405T2 (de) 2003-07-10
JP2001524092A (ja) 2001-11-27
WO1998047888A1 (en) 1998-10-29
EP0973760B1 (de) 2002-11-13
AR012449A1 (es) 2000-10-18
JP3993643B2 (ja) 2007-10-17
CA2286822A1 (en) 1998-10-29
DK0973760T3 (da) 2003-03-03
PT973760E (pt) 2003-03-31
AU736137B2 (en) 2001-07-26

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8327 Change in the person/name/address of the patent owner

Owner name: SANOFI-AVENTIS DEUTSCHLAND GMBH, 65929 FRANKFURT,