ES2080837T5 - Uso de acido hialuronico en combinacion con acido ascorbico, agentes antitumorales y/o faine para el tratamiento del cancer. - Google Patents

Uso de acido hialuronico en combinacion con acido ascorbico, agentes antitumorales y/o faine para el tratamiento del cancer.

Info

Publication number
ES2080837T5
ES2080837T5 ES90914108T ES90914108T ES2080837T5 ES 2080837 T5 ES2080837 T5 ES 2080837T5 ES 90914108 T ES90914108 T ES 90914108T ES 90914108 T ES90914108 T ES 90914108T ES 2080837 T5 ES2080837 T5 ES 2080837T5
Authority
ES
Spain
Prior art keywords
acid
treatment
hialuronic
faine
cancer
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES90914108T
Other languages
English (en)
Spanish (es)
Other versions
ES2080837T3 (es
Inventor
Rudolf Edgar Falk
Samuel S Asculai
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Jagotec AG
Original Assignee
Jagotec AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=4140639&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ES2080837(T5) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Jagotec AG filed Critical Jagotec AG
Publication of ES2080837T3 publication Critical patent/ES2080837T3/es
Application granted granted Critical
Publication of ES2080837T5 publication Critical patent/ES2080837T5/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/095—Sulfur, selenium, or tellurium compounds, e.g. thiols
    • A61K31/10—Sulfides; Sulfoxides; Sulfones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A—HUMAN NECESSITIES
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A—HUMAN NECESSITIES
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    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/192—Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid 
    • A—HUMAN NECESSITIES
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    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A—HUMAN NECESSITIES
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    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A61K31/196—Carboxylic acids, e.g. valproic acid having an amino group the amino group being directly attached to a ring, e.g. anthranilic acid, mefenamic acid, diclofenac, chlorambucil
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    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
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    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
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    • A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
    • A61K31/404—Indoles, e.g. pindolol
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    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
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    • A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
    • A—HUMAN NECESSITIES
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    • A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
    • A61K31/5415—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame ortho- or peri-condensed with carbocyclic ring systems, e.g. phenothiazine, chlorpromazine, piroxicam
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    • A61K31/60—Salicylic acid; Derivatives thereof
    • A61K31/612—Salicylic acid; Derivatives thereof having the hydroxy group in position 2 esterified, e.g. salicylsulfuric acid
    • A61K31/616—Salicylic acid; Derivatives thereof having the hydroxy group in position 2 esterified, e.g. salicylsulfuric acid by carboxylic acids, e.g. acetylsalicylic acid
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    • A61K31/726—Glycosaminoglycans, i.e. mucopolysaccharides
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  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Dermatology (AREA)
  • Molecular Biology (AREA)
  • Inorganic Chemistry (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Immunology (AREA)
  • Oncology (AREA)
  • Obesity (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Communicable Diseases (AREA)
  • Cardiology (AREA)
  • Pulmonology (AREA)
  • Endocrinology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Medicinal Preparation (AREA)
ES90914108T 1989-09-21 1990-09-18 Uso de acido hialuronico en combinacion con acido ascorbico, agentes antitumorales y/o faine para el tratamiento del cancer. Expired - Lifetime ES2080837T5 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CA000612307A CA1340994C (en) 1989-09-21 1989-09-21 Treatment of conditions and disease

Publications (2)

Publication Number Publication Date
ES2080837T3 ES2080837T3 (es) 1996-02-16
ES2080837T5 true ES2080837T5 (es) 2002-03-01

Family

ID=4140639

Family Applications (2)

Application Number Title Priority Date Filing Date
ES90914108T Expired - Lifetime ES2080837T5 (es) 1989-09-21 1990-09-18 Uso de acido hialuronico en combinacion con acido ascorbico, agentes antitumorales y/o faine para el tratamiento del cancer.
ES95100186T Expired - Lifetime ES2186693T3 (es) 1989-09-21 1990-09-18 Uso combinado del acido hialuronico y de agentes terapeuticos para mejorar el efecto terapeutico.

Family Applications After (1)

Application Number Title Priority Date Filing Date
ES95100186T Expired - Lifetime ES2186693T3 (es) 1989-09-21 1990-09-18 Uso combinado del acido hialuronico y de agentes terapeuticos para mejorar el efecto terapeutico.

Country Status (26)

Country Link
US (14) US6069135A (member.php)
EP (2) EP0656213B1 (member.php)
JP (1) JP3256761B2 (member.php)
KR (1) KR920700697A (member.php)
CN (1) CN1101228C (member.php)
AP (1) AP175A (member.php)
AT (2) ATE131068T1 (member.php)
AU (3) AU6433090A (member.php)
BR (1) BR9006924A (member.php)
CA (2) CA1340994C (member.php)
DE (2) DE69034018T2 (member.php)
DK (2) DK0656213T3 (member.php)
ES (2) ES2080837T5 (member.php)
FI (1) FI912470A0 (member.php)
HK (1) HK44797A (member.php)
HU (2) HU220758B1 (member.php)
IL (1) IL95745A (member.php)
IN (1) IN171745B (member.php)
LT (1) LT3545B (member.php)
NO (1) NO911952L (member.php)
RO (1) RO112812B1 (member.php)
RU (1) RU2146139C1 (member.php)
SG (1) SG49658A1 (member.php)
SK (1) SK459890A3 (member.php)
WO (1) WO1991004058A2 (member.php)
ZA (1) ZA907564B (member.php)

Families Citing this family (248)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1340994C (en) * 1989-09-21 2000-05-16 Rudolf Edgar Dr. Falk Treatment of conditions and disease
ES2146200T3 (es) * 1990-02-13 2000-08-01 Ethicon Inc Medicamentos inducidos peritonealmente.
CA2061566C (en) * 1992-02-20 2002-07-09 Rudolf E. Falk Treatment of disease employing hyaluronic acid and nsaids
US5639738A (en) * 1992-02-20 1997-06-17 Hyal Pharmaceutical Corporation Treatment of basal cell carcinoma and actinic keratosis employing hyaluronic acid and NSAIDs
CA2061703C (en) * 1992-02-20 2002-07-02 Rudolf E. Falk Formulations containing hyaluronic acid
US5733891A (en) * 1990-10-18 1998-03-31 Shiseido Co., Ltd. Compound for medicinal ingredient and hyaluronic acid and process for producing the same
CA2070672C (en) * 1990-10-18 2002-10-08 Kazuo Akima Compound of medicinal ingredient and hyaluronic acid and process for producing the same
US5629287A (en) * 1991-01-18 1997-05-13 University College London Depot formulations
US5610148A (en) * 1991-01-18 1997-03-11 University College London Macroscopically oriented cell adhesion protein for wound treatment
US5416071A (en) * 1991-03-12 1995-05-16 Takeda Chemical Industries, Ltd. Water-soluble composition for sustained-release containing epo and hyaluronic acid
CA2062659A1 (en) * 1991-03-12 1992-09-13 Yasutaka Igari Composition for sustained-release of erythropoietin
US6432405B1 (en) * 1991-03-15 2002-08-13 Duke University Method of inhibiting HIV infection with CD44 and anti-CD44 antibodies
CA2079205C (en) * 1992-09-25 1998-02-10 Rudolf Edgar Falk Use of hyaluronic acid and forms to prevent arterial restenosis
US5817644A (en) * 1991-07-03 1998-10-06 Hyal Pharmaceutical Corporation Targeting of dosages of medicine and therapeutic agents
CA2122519C (en) * 1994-04-29 2001-02-20 Rudolf Edgar Dr. Falk Cancer treatment and metastasis prevention
WO1994007505A1 (en) * 1991-07-03 1994-04-14 Norpharmco Inc. Use of hyaluronic acid and forms to prevent arterial restenosis
US5990095A (en) * 1991-07-03 1999-11-23 Hyal Pharmaceutical Corporation Use of hyaluronic acid and forms to prevent arterial restenosis
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US6048844A (en) 2000-04-11
HU211953A9 (en) 1996-01-29
JPH04504579A (ja) 1992-08-13
US5830882A (en) 1998-11-03
AU1485097A (en) 1997-05-22
CA2042034A1 (en) 1991-03-22
EP0656213A1 (en) 1995-06-07
NO911952D0 (no) 1991-05-21
FI912470A0 (fi) 1991-05-21
NO911952L (no) 1991-07-05
EP0656213B1 (en) 2002-11-13
US5929048A (en) 1999-07-27
LTIP1582A (en) 1995-06-26
US5985850A (en) 1999-11-16
US5914314A (en) 1999-06-22

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