ES2080954T3 - Uso de beta-aletina en cultivos de celulas y en terapia. - Google Patents

Uso de beta-aletina en cultivos de celulas y en terapia.

Info

Publication number
ES2080954T3
ES2080954T3 ES91912761T ES91912761T ES2080954T3 ES 2080954 T3 ES2080954 T3 ES 2080954T3 ES 91912761 T ES91912761 T ES 91912761T ES 91912761 T ES91912761 T ES 91912761T ES 2080954 T3 ES2080954 T3 ES 2080954T3
Authority
ES
Spain
Prior art keywords
beta
aletina
therapy
crops
cell
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES91912761T
Other languages
English (en)
Inventor
Galen Daryl Knight
Paul Leslie Mann
Terence Joseph Scallen
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
University of New Mexico UNM
Original Assignee
University of New Mexico UNM
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by University of New Mexico UNM filed Critical University of New Mexico UNM
Application granted granted Critical
Publication of ES2080954T3 publication Critical patent/ES2080954T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/0081—Purging biological preparations of unwanted cells
    • C12N5/0093—Purging against cancer cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0634—Cells from the blood or the immune system
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/067—Hepatocytes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K2035/124—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells the cells being hematopoietic, bone marrow derived or blood cells
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/999—Small molecules not provided for elsewhere

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Cell Biology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Hematology (AREA)
  • Epidemiology (AREA)
  • Oncology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

LA (BETA)-ALETINA SE UTILIZA PARA LA DIFERENCIACION Y VITALIZACION DE CELULAS, TANTO EN APLICACIONES IN VIVO COMO IN VITRO. ENTRE LAS APLICACIONES PARTICULARES CABE INCLUIR EN USO DE LA (BETA)-ALETINA EN EL TRATAMIENTO DE TRASTORNOS Y ENFERMEDADES INMUNES, EN EL TRATAMIENTO DE LA NEOPLASIA Y EN LA PROMOCION DE CULTIVOS DE CELULAS.
ES91912761T 1990-07-06 1991-07-08 Uso de beta-aletina en cultivos de celulas y en terapia. Expired - Lifetime ES2080954T3 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US54910490A 1990-07-06 1990-07-06
US54910390A 1990-07-06 1990-07-06

Publications (1)

Publication Number Publication Date
ES2080954T3 true ES2080954T3 (es) 1996-02-16

Family

ID=27069009

Family Applications (1)

Application Number Title Priority Date Filing Date
ES91912761T Expired - Lifetime ES2080954T3 (es) 1990-07-06 1991-07-08 Uso de beta-aletina en cultivos de celulas y en terapia.

Country Status (9)

Country Link
EP (1) EP0538330B1 (es)
JP (1) JP3319597B2 (es)
AT (1) ATE128964T1 (es)
AU (1) AU646875B2 (es)
DE (1) DE69113802T2 (es)
DK (1) DK0538330T3 (es)
ES (1) ES2080954T3 (es)
GR (1) GR3018632T3 (es)
WO (1) WO1992000960A1 (es)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6245561B1 (en) 1990-07-06 2001-06-12 University Of New Mexico β-alethine use in cell culture and therapy
ATE186048T1 (de) * 1990-07-06 1999-11-15 Univ New Mexico Vitalethin und seine anwendung in zellkultur und therapie
US5643966A (en) * 1990-07-06 1997-07-01 University Of New Mexico β-alethine as anti-tumor agent
WO1994026259A1 (en) * 1993-05-12 1994-11-24 Oculon Corporation Chemical prevention or reversal of cataract by phase separation inhibitors
WO1997014306A1 (en) * 1995-10-17 1997-04-24 Dovetail Technologies, Inc. Low molecular weight cell, bone marrow and immune stimulants
AU2874099A (en) * 1998-02-24 1999-09-06 Dovetail Technologies, Inc. Low molecular weight compounds administered together with anti-cancer agents to treat cancer and pharmaceutical compositions thereof
US6762174B1 (en) 1998-02-24 2004-07-13 Dovetail Technologies, Inc. Low molecular weight compounds administered together with anti-cancer agents to prevent or treat cancer and pharmaceutical compositions thereof

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4552765A (en) * 1982-05-14 1985-11-12 Santen Pharmaceutical Co., Ltd. Aletheine derivatives
JPS5973515A (ja) * 1982-10-20 1984-04-25 Santen Pharmaceut Co Ltd 肝障害抑制剤

Also Published As

Publication number Publication date
AU8207791A (en) 1992-02-04
GR3018632T3 (en) 1996-04-30
AU646875B2 (en) 1994-03-10
JPH05508769A (ja) 1993-12-09
ATE128964T1 (de) 1995-10-15
WO1992000960A1 (en) 1992-01-23
EP0538330A4 (en) 1993-07-07
JP3319597B2 (ja) 2002-09-03
DK0538330T3 (da) 1996-02-26
EP0538330B1 (en) 1995-10-11
EP0538330A1 (en) 1993-04-28
DE69113802T2 (de) 1996-05-15
DE69113802D1 (de) 1995-11-16

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