EE9800288A - PPAR-gamma agonistaktiivsusega asendatud 4-hüdroksüfenüülalkaanhapete derivaadid - Google Patents

PPAR-gamma agonistaktiivsusega asendatud 4-hüdroksüfenüülalkaanhapete derivaadid

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Publication number
EE9800288A
EE9800288A EE9800288A EE9800288A EE9800288A EE 9800288 A EE9800288 A EE 9800288A EE 9800288 A EE9800288 A EE 9800288A EE 9800288 A EE9800288 A EE 9800288A EE 9800288 A EE9800288 A EE 9800288A
Authority
EE
Estonia
Prior art keywords
derivatives
agonist activity
ppar gamma
gamma agonist
acids substituted
Prior art date
Application number
EE9800288A
Other languages
English (en)
Estonian (et)
Inventor
Anthony Mook Robert Jr.
Richard Henke Brad
Norman Deaton David
Loren Collins Jon
Edmond Cobb Jeffrey
Jude Sharp Matthew
Mark O'callaghan John
Alan Erickson Greg
Evan Boswell Grady
Mark Willson Timothy
Kaldor Istvan
Brackeen Markus
Original Assignee
Glaxo Group Limited
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=10789571&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=EE9800288(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Glaxo Group Limited filed Critical Glaxo Group Limited
Publication of EE9800288A publication Critical patent/EE9800288A/xx

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    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/62—Oxygen or sulfur atoms
    • C07D213/63—One oxygen atom
    • C07D213/64—One oxygen atom attached in position 2 or 6
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    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/192—Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid 
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    • A61K31/216—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acids having aromatic rings, e.g. benactizyne, clofibrate
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    • A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline 
    • A61K31/353—3,4-Dihydrobenzopyrans, e.g. chroman, catechin
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    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
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    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
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EE9800288A 1996-02-28 1997-02-26 PPAR-gamma agonistaktiivsusega asendatud 4-hüdroksüfenüülalkaanhapete derivaadid EE9800288A (et)

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