SE9801990D0 - New 3-aryl propionic acid derivatives and analogs - Google Patents
New 3-aryl propionic acid derivatives and analogsInfo
- Publication number
- SE9801990D0 SE9801990D0 SE9801990A SE9801990A SE9801990D0 SE 9801990 D0 SE9801990 D0 SE 9801990D0 SE 9801990 A SE9801990 A SE 9801990A SE 9801990 A SE9801990 A SE 9801990A SE 9801990 D0 SE9801990 D0 SE 9801990D0
- Authority
- SE
- Sweden
- Prior art keywords
- analogs
- new
- propionic acid
- acid derivatives
- aryl propionic
- Prior art date
Links
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C233/00—Carboxylic acid amides
- C07C233/01—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
- C07C233/16—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms
- C07C233/24—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by a carbon atom of a six-membered aromatic ring
- C07C233/29—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by a carbon atom of a six-membered aromatic ring having the carbon atom of the carboxamide group bound to an acyclic carbon atom of a carbon skeleton containing six-membered aromatic rings
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
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- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C217/00—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton
- C07C217/76—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having amino groups bound to carbon atoms of six-membered aromatic rings and etherified hydroxy groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C233/00—Carboxylic acid amides
- C07C233/01—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
- C07C233/16—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms
- C07C233/24—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by a carbon atom of a six-membered aromatic ring
- C07C233/25—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by a carbon atom of a six-membered aromatic ring having the carbon atom of the carboxamide group bound to a hydrogen atom or to a carbon atom of an acyclic saturated carbon skeleton
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C233/00—Carboxylic acid amides
- C07C233/64—Carboxylic acid amides having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings
- C07C233/67—Carboxylic acid amides having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms
- C07C233/75—Carboxylic acid amides having carbon atoms of carboxamide groups bound to carbon atoms of six-membered aromatic rings having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by singly-bound oxygen atoms with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by a carbon atom of a six-membered aromatic ring
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- C—CHEMISTRY; METALLURGY
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- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C255/00—Carboxylic acid nitriles
- C07C255/49—Carboxylic acid nitriles having cyano groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton
- C07C255/54—Carboxylic acid nitriles having cyano groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton containing cyano groups and etherified hydroxy groups bound to the carbon skeleton
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- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C271/00—Derivatives of carbamic acids, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
- C07C271/06—Esters of carbamic acids
- C07C271/08—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms
- C07C271/26—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atom of at least one of the carbamate groups bound to a carbon atom of a six-membered aromatic ring
- C07C271/28—Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atom of at least one of the carbamate groups bound to a carbon atom of a six-membered aromatic ring to a carbon atom of a non-condensed six-membered aromatic ring
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- C07C271/38—Esters of carbamic acids having oxygen atoms of carbamate groups bound to carbon atoms of rings other than six-membered aromatic rings with the nitrogen atom of at least one of the carbamate groups bound to a carbon atom of a six-membered aromatic ring
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- C07C271/00—Derivatives of carbamic acids, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
- C07C271/06—Esters of carbamic acids
- C07C271/40—Esters of carbamic acids having oxygen atoms of carbamate groups bound to carbon atoms of six-membered aromatic rings
- C07C271/42—Esters of carbamic acids having oxygen atoms of carbamate groups bound to carbon atoms of six-membered aromatic rings with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms
- C07C271/44—Esters of carbamic acids having oxygen atoms of carbamate groups bound to carbon atoms of six-membered aromatic rings with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms to hydrogen atoms or to carbon atoms of unsubstituted hydrocarbon radicals
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- C07C271/00—Derivatives of carbamic acids, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
- C07C271/06—Esters of carbamic acids
- C07C271/40—Esters of carbamic acids having oxygen atoms of carbamate groups bound to carbon atoms of six-membered aromatic rings
- C07C271/58—Esters of carbamic acids having oxygen atoms of carbamate groups bound to carbon atoms of six-membered aromatic rings with the nitrogen atom of at least one of the carbamate groups bound to a carbon atom of a six-membered aromatic ring
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- C07C275/00—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
- C07C275/28—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton
- C07C275/32—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton being further substituted by singly-bound oxygen atoms
- C07C275/34—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton being further substituted by singly-bound oxygen atoms having nitrogen atoms of urea groups and singly-bound oxygen atoms bound to carbon atoms of the same non-condensed six-membered aromatic ring
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- C—CHEMISTRY; METALLURGY
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- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C309/00—Sulfonic acids; Halides, esters, or anhydrides thereof
- C07C309/63—Esters of sulfonic acids
- C07C309/64—Esters of sulfonic acids having sulfur atoms of esterified sulfo groups bound to acyclic carbon atoms
- C07C309/65—Esters of sulfonic acids having sulfur atoms of esterified sulfo groups bound to acyclic carbon atoms of a saturated carbon skeleton
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- C07—ORGANIC CHEMISTRY
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- C07C309/00—Sulfonic acids; Halides, esters, or anhydrides thereof
- C07C309/63—Esters of sulfonic acids
- C07C309/64—Esters of sulfonic acids having sulfur atoms of esterified sulfo groups bound to acyclic carbon atoms
- C07C309/65—Esters of sulfonic acids having sulfur atoms of esterified sulfo groups bound to acyclic carbon atoms of a saturated carbon skeleton
- C07C309/66—Methanesulfonates
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- C—CHEMISTRY; METALLURGY
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- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C309/00—Sulfonic acids; Halides, esters, or anhydrides thereof
- C07C309/63—Esters of sulfonic acids
- C07C309/72—Esters of sulfonic acids having sulfur atoms of esterified sulfo groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton
- C07C309/73—Esters of sulfonic acids having sulfur atoms of esterified sulfo groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton to carbon atoms of non-condensed six-membered aromatic rings
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- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C311/00—Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
- C07C311/01—Sulfonamides having sulfur atoms of sulfonamide groups bound to acyclic carbon atoms
- C07C311/02—Sulfonamides having sulfur atoms of sulfonamide groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton
- C07C311/08—Sulfonamides having sulfur atoms of sulfonamide groups bound to acyclic carbon atoms of an acyclic saturated carbon skeleton having the nitrogen atom of at least one of the sulfonamide groups bound to a carbon atom of a six-membered aromatic ring
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- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C311/00—Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
- C07C311/01—Sulfonamides having sulfur atoms of sulfonamide groups bound to acyclic carbon atoms
- C07C311/12—Sulfonamides having sulfur atoms of sulfonamide groups bound to acyclic carbon atoms of an unsaturated carbon skeleton containing rings
- C07C311/13—Sulfonamides having sulfur atoms of sulfonamide groups bound to acyclic carbon atoms of an unsaturated carbon skeleton containing rings the carbon skeleton containing six-membered aromatic rings
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- C—CHEMISTRY; METALLURGY
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- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C311/00—Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
- C07C311/15—Sulfonamides having sulfur atoms of sulfonamide groups bound to carbon atoms of six-membered aromatic rings
- C07C311/16—Sulfonamides having sulfur atoms of sulfonamide groups bound to carbon atoms of six-membered aromatic rings having the nitrogen atom of at least one of the sulfonamide groups bound to hydrogen atoms or to an acyclic carbon atom
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- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C317/00—Sulfones; Sulfoxides
- C07C317/16—Sulfones; Sulfoxides having sulfone or sulfoxide groups and singly-bound oxygen atoms bound to the same carbon skeleton
- C07C317/22—Sulfones; Sulfoxides having sulfone or sulfoxide groups and singly-bound oxygen atoms bound to the same carbon skeleton with sulfone or sulfoxide groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton
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- C07C317/00—Sulfones; Sulfoxides
- C07C317/26—Sulfones; Sulfoxides having sulfone or sulfoxide groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton
- C07C317/28—Sulfones; Sulfoxides having sulfone or sulfoxide groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton with sulfone or sulfoxide groups bound to acyclic carbon atoms of the carbon skeleton
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- C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
- C07C323/10—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and singly-bound oxygen atoms bound to the same carbon skeleton
- C07C323/18—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and singly-bound oxygen atoms bound to the same carbon skeleton having the sulfur atom of at least one of the thio groups bound to a carbon atom of a six-membered aromatic ring of the carbon skeleton
- C07C323/19—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and singly-bound oxygen atoms bound to the same carbon skeleton having the sulfur atom of at least one of the thio groups bound to a carbon atom of a six-membered aromatic ring of the carbon skeleton with singly-bound oxygen atoms bound to acyclic carbon atoms of the carbon skeleton
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- C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
- C07C323/23—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton
- C07C323/39—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton at least one of the nitrogen atoms being part of any of the groups, X being a hetero atom, Y being any atom
- C07C323/43—Y being a hetero atom
- C07C323/44—X or Y being nitrogen atoms
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- C07C323/50—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton
- C07C323/51—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton
- C07C323/56—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton containing six-membered aromatic rings
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- C07C335/00—Thioureas, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
- C07C335/04—Derivatives of thiourea
- C07C335/16—Derivatives of thiourea having nitrogen atoms of thiourea groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton
- C07C335/18—Derivatives of thiourea having nitrogen atoms of thiourea groups bound to carbon atoms of six-membered aromatic rings of a carbon skeleton being further substituted by singly-bound oxygen atoms
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- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B2200/00—Indexing scheme relating to specific properties of organic compounds
- C07B2200/07—Optical isomers
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- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
- C07C2601/14—The ring being saturated
Priority Applications (68)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
SE9801990A SE9801990D0 (sv) | 1998-06-04 | 1998-06-04 | New 3-aryl propionic acid derivatives and analogs |
MA25591A MA26634A1 (fr) | 1998-06-04 | 1999-05-20 | Nouveaux derives de l'acide 3-aryl propionique et analogues |
DZ990099A DZ2799A1 (fr) | 1998-06-04 | 1999-05-23 | Nouveaux dérivés de l'acide 3-aryl propionique et analogues. |
TW088108577A TW548263B (en) | 1998-06-04 | 1999-05-25 | New 3-aryl propionic acid derivatives and analogs |
TW088108575A TW446694B (en) | 1998-06-04 | 1999-05-25 | Novel 3-aryl-2-hydroxypropionic acid derivative for use in conditions associated with insulin resistance and pharmaceutical composition containing same |
MA25601A MA26637A1 (fr) | 1998-06-04 | 1999-05-28 | Nouveau derive iii de l'acide 3-aryl-2-hydroxypropionique. |
TR2000/03543T TR200003543T2 (tr) | 1998-06-04 | 1999-05-31 | Yeni 3-aril-2-hidroksipropiyonik asit türevi III. |
PCT/SE1999/000942 WO1999062871A1 (en) | 1998-06-04 | 1999-05-31 | New 3-aryl propionic acid derivatives and analogs |
HU0103226A HUP0103226A3 (en) | 1998-06-04 | 1999-05-31 | New 3-aryl propionic acid derivatives and analogs |
AU46670/99A AU4667099A (en) | 1998-06-04 | 1999-05-31 | New 3-aryl-2-hydroxypropionic acid derivative iii |
DK99930060T DK1084102T3 (da) | 1998-06-04 | 1999-05-31 | Nye 3-arylpropionsyrederivater og analoge |
PL99344681A PL344681A1 (en) | 1998-06-04 | 1999-05-31 | New 3-aryl propionic acid derivatives and analogs |
IDW20002584A ID28164A (id) | 1998-06-04 | 1999-05-31 | Turunan iii asam 3-aril-2-hidroksipropionat baru |
IL13994299A IL139942A0 (en) | 1998-06-04 | 1999-05-31 | New 3-aryl-2-hydroxypropionic acid derivative iii |
TR2000/03583T TR200003583T2 (tr) | 1998-06-04 | 1999-05-31 | Yeni 3-aril propiyonik asit türevleri ve benzerleri. |
US09/341,935 US6362360B1 (en) | 1998-06-04 | 1999-05-31 | 3-aryl-2-hydroxypropionic acid derivative III |
SK1769-2000A SK284849B6 (sk) | 1998-06-04 | 1999-05-31 | Deriváty a analógy kyseliny 3-arylpropiónovej, spôsob ich prípravy, farmaceutické formulácie s ich obsahom a ich použitie |
PL99344682A PL344682A1 (en) | 1998-06-04 | 1999-05-31 | New 3-aryl-2-hydroxypropionic acid derivative iii |
DK99930058T DK1084101T3 (da) | 1998-06-04 | 1999-05-31 | Nyt 3-aryl-2-hydroxypropionsyrederivat (III) |
DE69915470T DE69915470T2 (de) | 1998-06-04 | 1999-05-31 | Neue 3-aryl-2-hydroxypropionsäure-derivate iii |
UA2000116620A UA66852C2 (uk) | 1998-06-04 | 1999-05-31 | Похідні та аналоги 3-арилпропіонової кислоти, спосіб їх отримання, фармацевтична композиція (варіанти) та спосіб профілактики та/або лікування асоційованих з резистентністю до інсуліну клінічних станів |
AT99930058T ATE261429T1 (de) | 1998-06-04 | 1999-05-31 | Neue 3-aryl-2-hydroxypropionsäure-derivate iii |
JP2000552083A JP3568897B2 (ja) | 1998-06-04 | 1999-05-31 | 新規な3−アリール−2−ヒドロキシプロピオン酸誘導体iii |
IDW20002669A ID29457A (id) | 1998-06-04 | 1999-05-31 | Turunan dan analog asam 3-aril propionat |
ES99930060T ES2209457T3 (es) | 1998-06-04 | 1999-05-31 | Nuevos derivados del acido 3-aril-propionico, y analogos. |
SI9930576T SI1084101T1 (en) | 1998-06-04 | 1999-05-31 | New 3-aryl-2-hydroxypropionic acid derivative iii |
SK1767-2000A SK17672000A3 (sk) | 1998-06-04 | 1999-05-31 | Derivát kyseliny 3-aryl-2-hydroxypropiónovej |
KR1020007013673A KR20010052529A (ko) | 1998-06-04 | 1999-05-31 | 신규한 3-아릴 프로피온산 유도체 및 동족체 |
CA002334374A CA2334374A1 (en) | 1998-06-04 | 1999-05-31 | New 3-aryl propionic acid derivatives and analogs |
CA002334107A CA2334107A1 (en) | 1998-06-04 | 1999-05-31 | New 3-aryl-2-hydroxypropionic acid derivative iii |
PT99930058T PT1084101E (pt) | 1998-06-04 | 1999-05-31 | Novo derivado do acido 3-aril-2-hidroxipropionico (iii) |
EP99930058A EP1084101B1 (en) | 1998-06-04 | 1999-05-31 | New 3-aryl-2-hydroxypropionic acid derivative iii |
BR9910913-1A BR9910913A (pt) | 1998-06-04 | 1999-05-31 | Composto, processo para a preparação de um composto, formulação farmacêutica, uso de um composto, e, processo para a profilaxia e/ou tratamento de condições clìnicas associadas com resistência a insulina |
CN99809354A CN1312795A (zh) | 1998-06-04 | 1999-05-31 | 新的3-芳基丙酸衍生物和其类似物 |
IL13963599A IL139635A0 (en) | 1998-06-04 | 1999-05-31 | New 3-aryl propionic acid derivatives and analogs |
EP99930060A EP1084102B1 (en) | 1998-06-04 | 1999-05-31 | New 3-aryl propionic acid derivatives and analogs |
PCT/SE1999/000940 WO1999062870A1 (en) | 1998-06-04 | 1999-05-31 | New 3-aryl-2-hydroxypropionic acid derivative iii |
NZ508453A NZ508453A (en) | 1998-06-04 | 1999-05-31 | New 3-aryl propionic acid derivatives and analogs and their use in the treatment of insulin resistance |
CN99809355A CN1311769A (zh) | 1998-06-04 | 1999-05-31 | 新的3-芳基-2-羟基丙酸衍生物iii |
EEP200000725A EE04463B1 (et) | 1998-06-04 | 1999-05-31 | 3-arüülpropaanhappe derivaadid ja nende analoogid, nende valmistamise meetod, neid sisaldavad ravimkoostised ja ühendid kasutamiseks ravis |
AU46672/99A AU752262B2 (en) | 1998-06-04 | 1999-05-31 | New 3-aryl propionic acid derivatives and analogs |
DE69911770T DE69911770T2 (de) | 1998-06-04 | 1999-05-31 | Neue 3-aryl-propionsäurederivate und analoge |
AT99930060T ATE251130T1 (de) | 1998-06-04 | 1999-05-31 | Neue 3-aryl-propionsäurederivate und analoge |
BR9910921-2A BR9910921A (pt) | 1998-06-04 | 1999-05-31 | Composto, processo para preparar o mesmo, formulação farmacêutica, uso de um composto, e, processo para a profilaxia e/ou tratamento de condições clìnicas associadas com a resistência à insulina |
SI9930452T SI1084102T1 (en) | 1998-06-04 | 1999-05-31 | New 3-aryl propionic acid derivatives and analogs |
EEP200000717A EE200000717A (et) | 1998-06-04 | 1999-05-31 | Uus 3-arüül-2-hüdroksüpropaanhappe derivaat III |
RU2000130191/04A RU2243214C2 (ru) | 1998-06-04 | 1999-05-31 | Новые производные и аналоги 3-арилпропионовой кислоты |
KR1020007013663A KR20010052522A (ko) | 1998-06-04 | 1999-05-31 | 신규한 3-아릴-2-히드록시프로피온산 유도체 ⅲ |
JP2000552084A JP3723739B2 (ja) | 1998-06-04 | 1999-05-31 | 新規3−アリールプロピオン酸誘導体および類似体 |
ES99930058T ES2216527T3 (es) | 1998-06-04 | 1999-05-31 | Nuevo derivado (iii) de acido 3-aril-2-hidroxipropionico. |
PT99930060T PT1084102E (pt) | 1998-06-04 | 1999-05-31 | Novos derivados do acido 3-aril-propionico e analogos |
US09/341,931 US6630600B1 (en) | 1998-06-04 | 1999-05-31 | 3-aryl propionic acid derivatives and analogs |
TNTNSN99107A TNSN99107A1 (fr) | 1998-06-04 | 1999-06-02 | Nouveau derive iii de l'acide 3-aryl-2-hydroxypropionique |
TNTNSN99103A TNSN99103A1 (fr) | 1998-06-04 | 1999-06-02 | Nouveaux derives de l'acide 3-aryl propionique et analogues |
MYPI99002185A MY129581A (en) | 1998-06-04 | 1999-06-02 | New 3-aryl propionic acid derivatives and analogs |
ARP990102636A AR019853A1 (es) | 1998-06-04 | 1999-06-03 | Derivado del acido 3-aril-2-hidroxipropionico, proceso e intermediario para su preparacion, formulaciones farmaceuticas, uso de dicho compuesto en laelaboracion de un medicamento, metodo para la profilaxis y/o tratamiento de trastornos clinicos asociados con la resistencia a la insulina, y formulaci |
ARP990102634A AR035305A1 (es) | 1998-06-04 | 1999-06-03 | Derivados y analogos del acido 3-arilpropionico, proceso para su preparacion, formulaciones farmaceuticas, uso de los mismos en la elaboracion de medicamentos, y formulacion farmaceutica para usar en la profilaxis y/o tratamiento de trastornos clinicos asociados con la resistencia a la insulina |
ZA200006773A ZA200006773B (en) | 1998-06-04 | 2000-11-20 | New 3-aryl-2-hydroxypropionic acid derivative III. |
ZA200006771A ZA200006771B (en) | 1998-06-04 | 2000-11-20 | New 3-aryl propionic acid derivatives and analogs. |
IS5735A IS5735A (is) | 1998-06-04 | 2000-11-28 | Ný 3-arýl-2-hýdroxýprópínsýruafleiða III |
IS5744A IS5744A (is) | 1998-06-04 | 2000-11-29 | Nýjar 3-arýl-própíónsýruafleiður og -hliðstæður |
NO20006114A NO20006114L (no) | 1998-06-04 | 2000-12-01 | Nytt 3-aryl-2-hydroksypropionsyrederivat III |
NO20006116A NO20006116L (no) | 1998-06-04 | 2000-12-01 | Nye 3-arylpropionsyrederivater og -analoger |
HK01105768A HK1034957A1 (en) | 1998-06-04 | 2001-08-16 | New 3-aryl propionic acid derivatives and analogs |
US10/678,739 US20040229949A1 (en) | 1998-06-04 | 2003-10-02 | New 3-aryl propionic acid derivatives and analogs |
JP2004118663A JP2004256548A (ja) | 1998-06-04 | 2004-04-14 | 新規な3−アリール−2−ヒドロキシプロピオン酸誘導体iii |
JP2004183263A JP2004346079A (ja) | 1998-06-04 | 2004-06-22 | 新規3−アリールプロピオン酸誘導体および類似体 |
US11/388,942 US20060173204A1 (en) | 1998-06-04 | 2006-03-24 | New 3-aryl propionic acid derivatives and analogs |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
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SE9801990A SE9801990D0 (sv) | 1998-06-04 | 1998-06-04 | New 3-aryl propionic acid derivatives and analogs |
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SE9801990D0 true SE9801990D0 (sv) | 1998-06-04 |
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SE9801990A SE9801990D0 (sv) | 1998-06-04 | 1998-06-04 | New 3-aryl propionic acid derivatives and analogs |
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US (1) | US6362360B1 (sv) |
EP (1) | EP1084101B1 (sv) |
JP (2) | JP3568897B2 (sv) |
KR (1) | KR20010052522A (sv) |
CN (1) | CN1311769A (sv) |
AR (1) | AR019853A1 (sv) |
AT (1) | ATE261429T1 (sv) |
AU (1) | AU4667099A (sv) |
BR (1) | BR9910913A (sv) |
CA (1) | CA2334107A1 (sv) |
DE (1) | DE69915470T2 (sv) |
DK (1) | DK1084101T3 (sv) |
EE (1) | EE200000717A (sv) |
ES (1) | ES2216527T3 (sv) |
ID (1) | ID28164A (sv) |
IL (1) | IL139942A0 (sv) |
IS (1) | IS5735A (sv) |
MA (1) | MA26637A1 (sv) |
NO (1) | NO20006114L (sv) |
PL (1) | PL344682A1 (sv) |
PT (1) | PT1084101E (sv) |
SE (1) | SE9801990D0 (sv) |
SK (1) | SK17672000A3 (sv) |
TN (1) | TNSN99107A1 (sv) |
TR (1) | TR200003543T2 (sv) |
TW (1) | TW446694B (sv) |
WO (1) | WO1999062870A1 (sv) |
ZA (2) | ZA200006773B (sv) |
Families Citing this family (28)
Publication number | Priority date | Publication date | Assignee | Title |
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AU1198699A (en) * | 1997-10-27 | 1999-04-23 | Dr. Reddy's Research Foundation | Novel heterocyclic compounds and their use in medicine, process for their reparation and pharmaceutical compositions containing them |
SE9801992D0 (sv) * | 1998-06-04 | 1998-06-04 | Astra Ab | New 3-aryl-2-hydroxypropionic acid derivative I |
MA26634A1 (fr) | 1998-06-04 | 2004-12-20 | Astra Ab | Nouveaux derives de l'acide 3-aryl propionique et analogues |
TW574193B (en) | 1999-12-03 | 2004-02-01 | Astrazeneca Ab | Novel phenalkyloxy-phenyl derivatives, pharmaceutical composition containing the same and their uses |
CA2392038A1 (en) * | 1999-12-03 | 2001-06-07 | Astrazeneca Ab | Crystalline form of (s)-2 ethoxy-3-[4-(2-{4-methanesulfonyloxyphenyl} ethoxy) phenyl] propanoic acid |
SE9904421D0 (sv) * | 1999-12-03 | 1999-12-03 | Astra Ab | New compounds |
SE9904412D0 (sv) * | 1999-12-03 | 1999-12-03 | Astra Ab | Comminuted form |
SE9904415D0 (sv) | 1999-12-03 | 1999-12-03 | Astra Ab | New process |
AU2034601A (en) * | 1999-12-03 | 2001-06-12 | Astrazeneca Ab | Crystalline form of 3-(4-(2-(4-tert-butoxycarbonylaminophenyl)ethoxy)phenyl)-(s) 2-ethoxy propanoic acid |
US6559335B2 (en) | 2000-09-22 | 2003-05-06 | Dr. Reddy's Laboratories Limited | Process for the preparation of 3-aryl-2-hydroxy propanoic acid |
SE0101386D0 (sv) | 2001-04-20 | 2001-04-20 | Astrazeneca Ab | New compounds |
SE0101978D0 (sv) * | 2001-06-01 | 2001-06-01 | Astrazeneca Ab | New compounds |
SE0101980D0 (sv) * | 2001-06-01 | 2001-06-01 | Astrazeneca Ab | Pharmaceutical combination |
SE0101981D0 (sv) * | 2001-06-01 | 2001-06-01 | Astrazeneca Ab | Pharmaceutical combination |
SE0101982D0 (sv) * | 2001-06-01 | 2001-06-01 | Astrazeneca Ab | Pharmaceutical combination |
CA2449256A1 (en) | 2001-06-07 | 2002-12-19 | Eli Lilly And Company | Modulators of peroxisome proliferator activated receptors |
WO2003008362A1 (en) * | 2001-06-28 | 2003-01-30 | Dr. Reddy's Laboratories Ltd | Novel 3-aryl-2-hydroxy propanol derivatives and a process for their preparation |
WO2003002508A1 (en) * | 2001-06-28 | 2003-01-09 | Dr. Reddy's Research Foundation | Derivatives of para-ethoxy-phenillactic acid |
US6987123B2 (en) | 2001-07-26 | 2006-01-17 | Cadila Healthcare Limited | Heterocyclic compounds, their preparation, pharmaceutical compositions containing them and their use in medicine |
UA82835C2 (en) | 2001-12-03 | 2008-05-26 | Reddys Lab Ltd Dr | ?-aryl-?-oxysubstituted propionuc acid derivatives and pharmaceutical composition based thereon |
WO2003051841A2 (en) * | 2001-12-14 | 2003-06-26 | Novo Nordisk A/S | Compounds and uses thereof for decreasing activity of hormone-sensitive lipase |
SE0104333D0 (sv) | 2001-12-19 | 2001-12-19 | Astrazeneca Ab | Therapeutic agents |
GB0314075D0 (en) * | 2003-06-18 | 2003-07-23 | Astrazeneca Ab | Therapeutic agents |
FR2872159B1 (fr) * | 2004-06-28 | 2007-10-05 | Merck Sante Soc Par Actions Si | Nouveaux derives acides carboxyliques phenyliques et leur utilisation dans le traitement du diabete |
FR2917086B1 (fr) * | 2007-06-05 | 2009-07-17 | Galderma Res & Dev | Nouveaux derives d'acide 3-phenyl acrylique activateurs des recepteurs de type ppar, leur methode de preparation et leur utilisation dans des compositions cosmetiques ou pharmaceutiques. |
PT2637646T (pt) | 2010-11-08 | 2016-08-17 | Albireo Ab | Uma combinação farmacêutica que compreende um inibidor do ibat e um sequestrador de ácido biliar |
SG190029A1 (en) | 2010-11-08 | 2013-06-28 | Albireo Ab | Ibat inhibitors for the treatment of liver diseases |
WO2012177956A1 (en) * | 2011-06-23 | 2012-12-27 | Metabolic Solutions Development Comapny, Llc | Ppar-sparing compounds for use in the treatment of diabetes and other metabolic diseases |
Family Cites Families (7)
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IL77843A (en) * | 1985-02-11 | 1989-07-31 | Syntex Inc | Dihydropyridine derivatives,process and novel intermediates for their preparation and pharmaceutical compositions containing them |
ZA9610738B (en) * | 1995-12-22 | 1997-06-24 | Warner Lambert Co | Subtype selective nmda receptor ligands and the use thereof |
GB9604242D0 (en) * | 1996-02-28 | 1996-05-01 | Glaxo Wellcome Inc | Chemical compounds |
AU708919B2 (en) * | 1996-04-04 | 1999-08-19 | Sankyo Company Limited | Phenylalkylcarboxylic acid derivatives |
FR2764889B1 (fr) * | 1997-06-20 | 2000-09-01 | Sod Conseils Rech Applic | Nouveaux derives du 2-(iminomethyl)amino-phenyle, leur preparation, leur application a titre de medicaments et les compositions pharmaceutiques les contenant |
SE9702305D0 (sv) | 1997-06-17 | 1997-06-17 | Astra Ab | New thiazolidinedione, oxazolidinedione and oxadiazolidinedione derivatives |
WO1999012925A1 (fr) * | 1997-09-10 | 1999-03-18 | Ajinomoto Co., Inc. | DERIVES DE 5,11-DIHYDRODIBENZ[b,e] [1,4]OXAZEPINE ET COMPOSITIONS MEDICAMENTEUSES LES CONTENANT |
-
1998
- 1998-06-04 SE SE9801990A patent/SE9801990D0/sv unknown
-
1999
- 1999-05-25 TW TW088108575A patent/TW446694B/zh not_active IP Right Cessation
- 1999-05-28 MA MA25601A patent/MA26637A1/fr unknown
- 1999-05-31 CA CA002334107A patent/CA2334107A1/en not_active Abandoned
- 1999-05-31 IL IL13994299A patent/IL139942A0/xx unknown
- 1999-05-31 BR BR9910913-1A patent/BR9910913A/pt not_active IP Right Cessation
- 1999-05-31 SK SK1767-2000A patent/SK17672000A3/sk unknown
- 1999-05-31 ID IDW20002584A patent/ID28164A/id unknown
- 1999-05-31 PT PT99930058T patent/PT1084101E/pt unknown
- 1999-05-31 AT AT99930058T patent/ATE261429T1/de not_active IP Right Cessation
- 1999-05-31 CN CN99809355A patent/CN1311769A/zh active Pending
- 1999-05-31 EE EEP200000717A patent/EE200000717A/xx unknown
- 1999-05-31 DE DE69915470T patent/DE69915470T2/de not_active Expired - Fee Related
- 1999-05-31 KR KR1020007013663A patent/KR20010052522A/ko not_active Application Discontinuation
- 1999-05-31 PL PL99344682A patent/PL344682A1/xx not_active Application Discontinuation
- 1999-05-31 TR TR2000/03543T patent/TR200003543T2/xx unknown
- 1999-05-31 AU AU46670/99A patent/AU4667099A/en not_active Abandoned
- 1999-05-31 EP EP99930058A patent/EP1084101B1/en not_active Expired - Lifetime
- 1999-05-31 JP JP2000552083A patent/JP3568897B2/ja not_active Expired - Fee Related
- 1999-05-31 DK DK99930058T patent/DK1084101T3/da active
- 1999-05-31 WO PCT/SE1999/000940 patent/WO1999062870A1/en not_active Application Discontinuation
- 1999-05-31 US US09/341,935 patent/US6362360B1/en not_active Expired - Fee Related
- 1999-05-31 ES ES99930058T patent/ES2216527T3/es not_active Expired - Lifetime
- 1999-06-02 TN TNTNSN99107A patent/TNSN99107A1/fr unknown
- 1999-06-03 AR ARP990102636A patent/AR019853A1/es not_active Application Discontinuation
-
2000
- 2000-11-20 ZA ZA200006773A patent/ZA200006773B/en unknown
- 2000-11-20 ZA ZA200006771A patent/ZA200006771B/en unknown
- 2000-11-28 IS IS5735A patent/IS5735A/is unknown
- 2000-12-01 NO NO20006114A patent/NO20006114L/no not_active Application Discontinuation
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2004
- 2004-04-14 JP JP2004118663A patent/JP2004256548A/ja active Pending
Also Published As
Publication number | Publication date |
---|---|
ATE261429T1 (de) | 2004-03-15 |
CA2334107A1 (en) | 1999-12-09 |
AU4667099A (en) | 1999-12-20 |
DK1084101T3 (da) | 2004-06-14 |
NO20006114L (no) | 2001-02-02 |
ZA200006773B (en) | 2002-02-20 |
TNSN99107A1 (fr) | 2005-11-10 |
EE200000717A (et) | 2001-08-15 |
DE69915470D1 (en) | 2004-04-15 |
AR019853A1 (es) | 2002-03-20 |
WO1999062870A1 (en) | 1999-12-09 |
TR200003543T2 (tr) | 2001-04-20 |
PT1084101E (pt) | 2004-07-30 |
BR9910913A (pt) | 2001-03-06 |
IL139942A0 (en) | 2002-02-10 |
JP3568897B2 (ja) | 2004-09-22 |
ZA200006771B (en) | 2002-05-20 |
CN1311769A (zh) | 2001-09-05 |
PL344682A1 (en) | 2001-11-19 |
DE69915470T2 (de) | 2005-02-24 |
MA26637A1 (fr) | 2004-12-20 |
NO20006114D0 (no) | 2000-12-01 |
EP1084101B1 (en) | 2004-03-10 |
TW446694B (en) | 2001-07-21 |
ID28164A (id) | 2001-05-10 |
IS5735A (is) | 2000-11-28 |
ES2216527T3 (es) | 2004-10-16 |
EP1084101A1 (en) | 2001-03-21 |
JP2002516898A (ja) | 2002-06-11 |
US6362360B1 (en) | 2002-03-26 |
JP2004256548A (ja) | 2004-09-16 |
SK17672000A3 (sk) | 2001-08-06 |
KR20010052522A (ko) | 2001-06-25 |
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