HUP9800523A2 - Inzulinszármazékok - Google Patents

Inzulinszármazékok

Info

Publication number
HUP9800523A2
HUP9800523A2 HU9800523A HUP9800523A HUP9800523A2 HU P9800523 A2 HUP9800523 A2 HU P9800523A2 HU 9800523 A HU9800523 A HU 9800523A HU P9800523 A HUP9800523 A HU P9800523A HU P9800523 A2 HUP9800523 A2 HU P9800523A2
Authority
HU
Hungary
Prior art keywords
insulin derivatives
insulin
diabetes
subject
derivatives
Prior art date
Application number
HU9800523A
Other languages
English (en)
Inventor
Jakob Brandt
Per Hertz Hansen
Svend Havelund
Ib Jonassen
Niels Christian Kaarsholm
Peter Kurtzhals
Jan Markussen
Original Assignee
Novo Nordisk A/S
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novo Nordisk A/S filed Critical Novo Nordisk A/S
Publication of HUP9800523A2 publication Critical patent/HUP9800523A2/hu
Publication of HUP9800523A3 publication Critical patent/HUP9800523A3/hu

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/62—Insulins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Diabetes (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Cardiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Endocrinology (AREA)
  • Veterinary Medicine (AREA)
  • Obesity (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Hospice & Palliative Care (AREA)
  • Hematology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Emergency Medicine (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

A találmány tárgya inzűlinszármazék, valamint őlyan módszer, amely azarra rászőrűló betegekben a diabetes kezelésére szőlgál. ŕ
HU9800523A 1995-03-17 1996-03-18 Insulin derivatives HUP9800523A3 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DK27695 1995-03-17

Publications (2)

Publication Number Publication Date
HUP9800523A2 true HUP9800523A2 (hu) 1998-06-29
HUP9800523A3 HUP9800523A3 (en) 1998-09-28

Family

ID=8091725

Family Applications (1)

Application Number Title Priority Date Filing Date
HU9800523A HUP9800523A3 (en) 1995-03-17 1996-03-18 Insulin derivatives

Country Status (14)

Country Link
EP (1) EP0871665B1 (hu)
JP (1) JP3872105B2 (hu)
KR (1) KR19980703039A (hu)
CN (1) CN1196061A (hu)
AT (1) ATE245659T1 (hu)
AU (1) AU720966B2 (hu)
BR (1) BR9607647A (hu)
CA (1) CA2215694A1 (hu)
CZ (1) CZ289343B6 (hu)
DE (1) DE69629210T2 (hu)
HU (1) HUP9800523A3 (hu)
NO (1) NO974270L (hu)
PL (1) PL183698B1 (hu)
WO (1) WO1996029344A1 (hu)

Families Citing this family (40)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5693609A (en) * 1994-11-17 1997-12-02 Eli Lilly And Company Acylated insulin analogs
US6451970B1 (en) 1996-02-21 2002-09-17 Novo Nordisk A/S Peptide derivatives
US6268343B1 (en) 1996-08-30 2001-07-31 Novo Nordisk A/S Derivatives of GLP-1 analogs
US6458924B2 (en) 1996-08-30 2002-10-01 Novo Nordisk A/S Derivatives of GLP-1 analogs
US7235627B2 (en) 1996-08-30 2007-06-26 Novo Nordisk A/S Derivatives of GLP-1 analogs
BR9813111A (pt) 1997-10-24 2000-08-15 Lilly Co Eli Composições de insulina insolúveis
CO4970787A1 (es) 1997-12-23 2000-11-07 Lilly Co Eli Composiciones insolubles de insulina y derivados de insulina que controlan la glucosa sanguinea
CN1202128C (zh) * 1998-12-08 2005-05-18 拜奥威神有限公司 修饰蛋白的免疫原性
TWI242000B (en) * 1998-12-10 2005-10-21 Univ Southern California Reversible aqueous pH sensitive lipidizing reagents, compositions and methods of use
ES2360182T3 (es) 2002-05-07 2011-06-01 Novo Nordisk A/S Formulaciones solubles que comprenden insulina monomérica e insulina acilada.
CN1247616C (zh) * 2002-07-19 2006-03-29 上海中科生龙达生物技术（集团）有限公司 新的单体胰岛素，药物组合物及其制法
EP2107069B1 (en) 2003-08-05 2013-01-16 Novo Nordisk A/S Novel insulin derivatives
JP2007532096A (ja) * 2003-11-14 2007-11-15 ノボ　ノルディスク　アクティーゼルスカブ アシル化されたインスリンの製造方法
DK2842576T3 (en) 2004-01-21 2017-10-16 Novo Nordisk Healthcare Ag Transglutaminase-mediated peptide conjugation
AU2005224026A1 (en) 2004-03-17 2005-09-29 7Tm Pharma A/S Y2 selective receptor agonists for therapeutic interventions
JP2007529463A (ja) 2004-03-17 2007-10-25 ７ティーエム ファーマ エイ／エス 治療的介入のためのｙ４選択性レセプターアゴニスト
ES2438145T3 (es) 2005-02-02 2014-01-16 Novo Nordisk A/S Nuevos derivados de insulina
EP2292653B1 (en) 2005-02-02 2014-05-21 Novo Nordisk A/S Novel insulin derivatives
PT1969004E (pt) 2005-12-28 2011-11-25 Novo Nordisk As Composições que compreendem uma insulina acilada e zinco e método para criar tais composições
EP2256129B1 (en) 2006-02-27 2012-05-09 Novo Nordisk A/S Insulin derivatives
MX2008014061A (es) * 2006-05-09 2008-11-14 Novo Nordisk As Derivado de insulina.
EP2049149B1 (en) 2006-07-31 2015-04-15 Novo Nordisk A/S Pegylated extended insulins
KR101729986B1 (ko) 2006-09-22 2017-04-25 노보 노르디스크 에이/에스 프로테아제 내성 인슐린 유사체
CN101674812B (zh) 2007-04-30 2013-12-11 诺沃-诺迪斯克有限公司 干燥蛋白组合物的方法、干燥的蛋白组合物和包含干燥的蛋白的药物组合物
JP5552046B2 (ja) 2007-06-13 2014-07-16 ノボ・ノルデイスク・エー／エス インスリン誘導体を含有する薬学的製剤
JP5715418B2 (ja) 2007-11-08 2015-05-07 ノボ・ノルデイスク・エー／エス インスリン誘導体
EP2058330A1 (en) * 2007-11-08 2009-05-13 Novo Nordisk A/S Insulin derivative
ES2618073T3 (es) * 2008-03-14 2017-06-20 Novo Nordisk A/S Análogos de insulina estabilizados frente a proteasas
DK2910570T3 (en) 2008-03-18 2017-01-30 Novo Nordisk As Protease-stabilized acylated insulin analogues.
EP2352513B1 (en) 2008-10-30 2016-09-14 Novo Nordisk A/S Treating diabetes melitus using insulin injections with less than daily injection frequency
RU2013123515A (ru) 2010-10-27 2014-12-10 Ново Нордиск А/С Лечение сахарного диабета с помощью инъекций инсулина, вводимых с различными интервалами
CN104364260B (zh) 2012-04-11 2017-02-22 诺和诺德股份有限公司 胰岛素制剂
US10137172B2 (en) 2013-04-30 2018-11-27 Novo Nordisk A/S Administration regime
CA2926701A1 (en) 2013-10-07 2015-04-16 Novo Nordisk A/S Novel derivative of an insulin analogue
AR099569A1 (es) 2014-02-28 2016-08-03 Novo Nordisk As Derivados de insulina y los usos médicos de estos
HUE055231T2 (hu) 2016-12-16 2021-11-29 Novo Nordisk As Inzulint tartalmazó gyógyászati készítmények
AR112480A1 (es) 2017-08-24 2019-10-30 Novo Nordisk As Composiciones de glp-1 y sus usos
US10335464B1 (en) 2018-06-26 2019-07-02 Novo Nordisk A/S Device for titrating basal insulin
EP3894391A1 (en) 2018-12-11 2021-10-20 Sanofi Peptide binder
US20230093542A1 (en) 2020-02-18 2023-03-23 Novo Nordisk A/S Glp-1 compositions and uses thereof

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3844211A1 (de) * 1988-12-29 1990-07-05 Hoechst Ag Neue insulinderivate, verfahren zu deren herstellung, ihre verwendung und eine sie enthaltende pharmazeutische zubereitung
DK155690D0 (da) * 1990-06-28 1990-06-28 Novo Nordisk As Nye peptider
PT792290E (pt) * 1993-09-17 2002-01-30 Novo Nordisk As Insulina acilada

Also Published As

Publication number Publication date
MX9707056A (es) 1997-11-29
AU720966B2 (en) 2000-06-22
AU4939696A (en) 1996-10-08
BR9607647A (pt) 1999-04-06
JP3872105B2 (ja) 2007-01-24
WO1996029344A1 (en) 1996-09-26
CN1196061A (zh) 1998-10-14
CA2215694A1 (en) 1996-09-26
KR19980703039A (ko) 1998-09-05
ATE245659T1 (de) 2003-08-15
CZ289997A3 (cs) 1998-01-14
DE69629210T2 (de) 2004-04-22
DE69629210D1 (de) 2003-08-28
HUP9800523A3 (en) 1998-09-28
EP0871665A1 (en) 1998-10-21
PL322299A1 (en) 1998-01-19
NO974270L (no) 1997-11-14
NO974270D0 (no) 1997-09-16
EP0871665B1 (en) 2003-07-23
PL183698B1 (pl) 2002-06-28
CZ289343B6 (cs) 2002-01-16
JPH11502110A (ja) 1999-02-23

Similar Documents

Publication Publication Date Title
HUP9800523A2 (hu) Inzulinszármazékok
PT723538E (pt) Compostos triciclicos de carbamato uteis para a ainibicao da funcao da proteina g e para o tratamento de doencas proliferativas
ATE151764T1 (de) Neue benzopyran-derivate, verfahren zu ihrer herstellung und ihre verwendung sowie die verbindungen enthaltenden zubereitungen
DK0966447T3 (da) Anvendelige små molekyler til behandling af betændelsessygdomme
NO20052755L (no) Krystallmodifikasjon av et N-fenyl-2-pyrimidinaminderivat, fremgangsmate for dens fremstilling og dens anvendelse.
EA199800857A1 (ru) Композиция для снятия боли и способ снятия боли
PT1333887E (pt) Metodo de tratamento de desordens musculares
ES2134847T3 (es) Derivados de taxol.
NO976063L (no) Fremgangsmåte for behandling av diabetes
DE50015623D1 (de) Kovalent verbrückte insulindimere
FI980862A (fi) Kiraalisia metyylifenyylioksatsolidinoneja
DE69425356T2 (de) Pro-Prodrugs, ihre Herstellung und Anwendung
NO973548L (no) Behandling av diabetisk neuropati
ATE239474T1 (de) Verwendung von levobupivacain
SE9702305D0 (sv) New thiazolidinedione, oxazolidinedione and oxadiazolidinedione derivatives
AU5343698A (en) New benzofuranone derivatives and a method for producing them
ITTO950099A0 (it) Catetere, particolarmente per il trattamento di aritmie cardiache.
DE60128100D1 (de) Analgetisches arzneimittel
DE69604071D1 (de) Oxazolidinone derivate, ihre herstellung und ihre therapeutische verwendung
AU7718796A (en) 4-hydroxycoumarin-3-carboxamides for the treatment of diabetes mellitus
GB9420747D0 (en) 1,5 benzodiazepine derivatives
TW330933B (en) Furanoeremophilane and eremophilanolide sesquiterpenes for treatment of diabetes
NO984651L (no) Anvendelse av benzonaftalenderivater for fremstilling av medikamenter for behandling av sykdommer i sentralnervesystemet
ITTO971062A0 (it) Farmaco per la cura dell'ircismo contenente un adrenocorticosteroide.
SE9500897D0 (sv) The pharmacological use of certain cystine derivatives