CA2006596C
(en)
*
|
1988-12-22 |
2000-09-05 |
Rika Ishikawa |
Chemically-modified g-csf
|
US7264944B1
(en)
*
|
1989-04-21 |
2007-09-04 |
Amgen Inc. |
TNF receptors, TNF binding proteins and DNAs coding for them
|
EP0393438B1
(de)
*
|
1989-04-21 |
2005-02-16 |
Amgen Inc. |
TNF-Rezeptor, TNF bindende Proteine und dafür kodierende DNAs
|
IL95031A
(en)
|
1989-07-18 |
2007-03-08 |
Amgen Inc |
A method of producing a recombinant human necrotic factor absorber
|
US6143866A
(en)
*
|
1989-07-18 |
2000-11-07 |
Amgen, Inc. |
Tumor necrosis factor (TNF) inhibitor and method for obtaining the same
|
US6552170B1
(en)
*
|
1990-04-06 |
2003-04-22 |
Amgen Inc. |
PEGylation reagents and compounds formed therewith
|
US5595732A
(en)
*
|
1991-03-25 |
1997-01-21 |
Hoffmann-La Roche Inc. |
Polyethylene-protein conjugates
|
US5880131A
(en)
*
|
1993-10-20 |
1999-03-09 |
Enzon, Inc. |
High molecular weight polymer-based prodrugs
|
US5919455A
(en)
|
1993-10-27 |
1999-07-06 |
Enzon, Inc. |
Non-antigenic branched polymer conjugates
|
US5951974A
(en)
*
|
1993-11-10 |
1999-09-14 |
Enzon, Inc. |
Interferon polymer conjugates
|
EP0730470B1
(en)
*
|
1993-11-10 |
2002-03-27 |
Enzon, Inc. |
Improved interferon polymer conjugates
|
AU1916295A
(en)
*
|
1994-02-08 |
1995-08-29 |
Amgen, Inc. |
Oral delivery of chemically modified proteins
|
US5730990A
(en)
*
|
1994-06-24 |
1998-03-24 |
Enzon, Inc. |
Non-antigenic amine derived polymers and polymer conjugates
|
US20030053982A1
(en)
*
|
1994-09-26 |
2003-03-20 |
Kinstler Olaf B. |
N-terminally chemically modified protein compositions and methods
|
DE4435087A1
(de)
*
|
1994-09-30 |
1996-04-04 |
Deutsches Krebsforsch |
Konjugat zur Behandlung von Infektions-, Autoimmun- und Hauterkrankungen
|
US5824784A
(en)
*
|
1994-10-12 |
1998-10-20 |
Amgen Inc. |
N-terminally chemically modified protein compositions and methods
|
US5738846A
(en)
*
|
1994-11-10 |
1998-04-14 |
Enzon, Inc. |
Interferon polymer conjugates and process for preparing the same
|
JP2758154B2
(ja)
*
|
1995-04-06 |
1998-05-28 |
エフ・ホフマン−ラ ロシユ アーゲー |
インターフェロンを含む液体製剤
|
DE19514087A1
(de)
*
|
1995-04-13 |
1996-10-17 |
Deutsches Krebsforsch |
Konjugat aus einem Wirkstoff, einem Polyether und ggfs. einem nicht als körperfremd angesehenen, nativen Protein
|
WO1997016204A1
(en)
|
1995-11-02 |
1997-05-09 |
Schering Corporation |
Continuous low-dose cytokine infusion therapy
|
US5908621A
(en)
*
|
1995-11-02 |
1999-06-01 |
Schering Corporation |
Polyethylene glycol modified interferon therapy
|
TW517067B
(en)
*
|
1996-05-31 |
2003-01-11 |
Hoffmann La Roche |
Interferon conjugates
|
TW555765B
(en)
|
1996-07-09 |
2003-10-01 |
Amgen Inc |
Low molecular weight soluble tumor necrosis factor type-I and type-II proteins
|
US6753165B1
(en)
*
|
1999-01-14 |
2004-06-22 |
Bolder Biotechnology, Inc. |
Methods for making proteins containing free cysteine residues
|
US7495087B2
(en)
|
1997-07-14 |
2009-02-24 |
Bolder Biotechnology, Inc. |
Cysteine muteins in the C-D loop of human interleukin-11
|
US7270809B2
(en)
*
|
1997-07-14 |
2007-09-18 |
Bolder Biotechnology, Inc. |
Cysteine variants of alpha interferon-2
|
US20080076706A1
(en)
|
1997-07-14 |
2008-03-27 |
Bolder Biotechnology, Inc. |
Derivatives of Growth Hormone and Related Proteins, and Methods of Use Thereof
|
BR9812267B1
(pt)
*
|
1997-07-14 |
2013-11-26 |
|
Hormônio de crescimento recombinante.
|
TR200000728T2
(tr)
*
|
1997-09-18 |
2000-09-21 |
F.Hoffmann-La Roche Ag |
Kronik hepatit C' nin tedavisinde IFN-alfa ve amantadin kullanımı.
|
US6180095B1
(en)
*
|
1997-12-17 |
2001-01-30 |
Enzon, Inc. |
Polymeric prodrugs of amino- and hydroxyl-containing bioactive agents
|
EP1037649B1
(en)
|
1997-12-17 |
2009-09-30 |
Enzon, Inc. |
Polymeric prodrugs of amino- and hydroxyl-containing bioactive agents
|
US5981709A
(en)
*
|
1997-12-19 |
1999-11-09 |
Enzon, Inc. |
α-interferon-polymer-conjugates having enhanced biological activity and methods of preparing the same
|
US5985263A
(en)
*
|
1997-12-19 |
1999-11-16 |
Enzon, Inc. |
Substantially pure histidine-linked protein polymer conjugates
|
FR2774687B1
(fr)
*
|
1998-02-06 |
2002-03-22 |
Inst Nat Sante Rech Med |
Lipopeptides contenant un fragment de l'interferon gamma, et leur utilisation dans des compositions pharmaceutiques
|
US6180096B1
(en)
|
1998-03-26 |
2001-01-30 |
Schering Corporation |
Formulations for protection of peg-interferon alpha conjugates
|
KR100420642B1
(ko)
*
|
1998-03-26 |
2004-03-02 |
쉐링 코포레이션 |
Peg-인터페론 알파 결합체의 보호에 사용되는 제형
|
CZ298579B6
(cs)
*
|
1998-04-28 |
2007-11-14 |
Applied Research Systems Ars Holding N. V. |
Konjugát polyolu a interferonu-beta
|
SK288038B6
(en)
|
1998-05-15 |
2013-01-02 |
Merck Sharp & Dohme |
Use of ribavirin and interferon alpha for manufacture pharmaceutical compositions for treating chronic hepatitis C infection
|
EP1079859B1
(en)
|
1998-05-22 |
2010-07-14 |
The Board Of Trustees Of The Leland Stanford Junior University |
Bifunctional molecules and therapies based thereon
|
ITMI981148A1
(it)
*
|
1998-05-22 |
1999-11-22 |
Therapicon Srl |
Utilizzo di lisozima c modificato per preparare composizioni medicinali per il trattamento di alcune gravi malattie
|
ES2251196T3
(es)
*
|
1998-06-08 |
2006-04-16 |
F. Hoffmann-La Roche Ag |
Uso de peg-ifn-alfa y ribavirina para el tratamiento de hepatitis c cronica.
|
US7223845B2
(en)
|
1998-06-16 |
2007-05-29 |
The Board Of Regents Of The University Of Oklahoma |
Synthetic glycosulfopeptides and methods of synthesis thereof
|
EP1087996B1
(en)
*
|
1998-06-16 |
2007-01-17 |
The Board of Regents of The University of Oklahoma |
Glycosulfopeptides and methods of synthesis and use thereof
|
US20030143662A1
(en)
*
|
1998-06-16 |
2003-07-31 |
Cummings Richard D. |
Glycosulfopeptide inhibitors of leukocyte rolling and methods of use thereof
|
LT2599503T
(lt)
|
1998-10-16 |
2017-06-26 |
Biogen Ma Inc. |
Interferono beta-1a polimero konjugatai ir jų panaudojimas
|
CN100480266C
(zh)
*
|
1998-10-16 |
2009-04-22 |
拜奥根Idec马萨诸塞公司 |
干扰素-β融合蛋白及用途
|
US6660843B1
(en)
*
|
1998-10-23 |
2003-12-09 |
Amgen Inc. |
Modified peptides as therapeutic agents
|
US8288126B2
(en)
|
1999-01-14 |
2012-10-16 |
Bolder Biotechnology, Inc. |
Methods for making proteins containing free cysteine residues
|
EP1144613B2
(en)
|
1999-01-14 |
2020-05-06 |
Bolder Biotechnology, Inc. |
Methods for making proteins containing free cysteine residues
|
EA004685B1
(ru)
*
|
1999-01-29 |
2004-06-24 |
Эмджен Инк. |
Конъюгаты гксф
|
US6362162B1
(en)
|
1999-04-08 |
2002-03-26 |
Schering Corporation |
CML Therapy
|
US6605273B2
(en)
|
1999-04-08 |
2003-08-12 |
Schering Corporation |
Renal cell carcinoma treatment
|
US6923966B2
(en)
|
1999-04-08 |
2005-08-02 |
Schering Corporation |
Melanoma therapy
|
HU230057B1
(hu)
|
1999-04-08 |
2015-06-29 |
Merck Sharp & Dohme Corp. |
Melanóma-kezelés
|
PE20010288A1
(es)
|
1999-07-02 |
2001-03-07 |
Hoffmann La Roche |
Derivados de eritropoyetina
|
EP1860188B1
(en)
|
1999-07-07 |
2011-05-04 |
ZymoGenetics, Inc. |
Human cytokine receptor
|
WO2001005819A1
(en)
*
|
1999-07-15 |
2001-01-25 |
Kuhnil Pharm. Co., Ltd. |
Novel water soluble-cyclosporine conjugated compounds
|
US7144574B2
(en)
*
|
1999-08-27 |
2006-12-05 |
Maxygen Aps |
Interferon β variants and conjugates
|
US6531122B1
(en)
*
|
1999-08-27 |
2003-03-11 |
Maxygen Aps |
Interferon-β variants and conjugates
|
US7431921B2
(en)
*
|
2000-04-14 |
2008-10-07 |
Maxygen Aps |
Interferon beta-like molecules
|
EP1224939A4
(en)
|
1999-10-12 |
2005-01-12 |
Santen Pharmaceutical Co Ltd |
INTERFERON-BASED COMPLEX AND ITS USE IN MEDICINE
|
SK8292002A3
(en)
*
|
1999-11-12 |
2002-12-03 |
Maxygen Holdings Ltd |
A conjugate exhibiting interferon gamma activity, nucleotide sequence encoding for a polypeptide fraction of conjugate, an expression vector and a host cell containing nucleotide sequence, pharmaceutical composition comprising the same and use thereof
|
US7230081B1
(en)
|
1999-11-12 |
2007-06-12 |
Maxygen Holdings, Ltd. |
Interferon gamma conjugates
|
US7498025B1
(en)
|
1999-11-19 |
2009-03-03 |
The Board Of Trustees Of The Leland Stanford Junior University |
Targeted bifunctional molecules and therapies based thereon
|
US7220552B1
(en)
|
1999-11-19 |
2007-05-22 |
The Board Of Trustees Of The Leland Stanford Junior University |
Bifunctional molecules and their use in the disruption of protein-protein interactions
|
US6887842B1
(en)
|
1999-11-19 |
2005-05-03 |
The Board Of Trustees Of The Leland Stanford Junior University |
Modulating a pharmacokinetic property of a drug by administering a bifunctional molecule containing the drug
|
DE60043895D1
(de)
|
1999-12-03 |
2010-04-08 |
Zymogenetics Inc |
Menschliches zytokinrezeptor
|
JP2003519478A
(ja)
|
2000-01-10 |
2003-06-24 |
マキシゲン・ホールディングズ・リミテッド |
G−csf結合体
|
WO2001052882A1
(en)
*
|
2000-01-24 |
2001-07-26 |
Schering Corporation |
Combination of temozolomide and pegylated interferon-alpha for treating cancer
|
EP1908477A3
(en)
*
|
2000-01-24 |
2008-06-11 |
Schering Corporation |
Combination of temozolomide and pegylated interferon-alpha for treating cancer
|
DE60138364D1
(de)
|
2000-02-11 |
2009-05-28 |
Bayer Healthcare Llc |
Gerinnungsfaktor vii oder viia konjugate
|
KR100353392B1
(ko)
*
|
2000-03-13 |
2002-09-18 |
선바이오(주) |
높은 생체 활성도를 갖는 생체 활성 단백질과 peg의결합체 제조방법
|
US6756037B2
(en)
|
2000-03-31 |
2004-06-29 |
Enzon, Inc. |
Polymer conjugates of biologically active agents and extension moieties for facilitating conjugation of biologically active agents to polymeric terminal groups
|
US6777387B2
(en)
|
2000-03-31 |
2004-08-17 |
Enzon Pharmaceuticals, Inc. |
Terminally-branched polymeric linkers containing extension moieties and polymeric conjugates containing the same
|
ATE421535T1
(de)
*
|
2000-10-16 |
2009-02-15 |
Chugai Pharmaceutical Co Ltd |
Peg-modifiziertes erythropoietin
|
US20020169290A1
(en)
*
|
2000-11-02 |
2002-11-14 |
Claus Bornaes |
New multimeric interferon beta polypeptides
|
EP1407017B1
(en)
|
2000-11-07 |
2009-06-03 |
ZymoGenetics, Inc. |
Human tumor necrosis factor receptor
|
CA2437989A1
(en)
*
|
2001-02-20 |
2002-08-29 |
Enzon, Inc. |
Terminally-branched polymeric linkers and polymeric conjugates containing the same
|
EP2301971A1
(en)
|
2001-02-20 |
2011-03-30 |
ZymoGenetics, L.L.C. |
Antibodies that bind both BCMA and TACI
|
MXPA03007619A
(es)
|
2001-02-27 |
2003-12-04 |
Maxygen Aps |
Nuevas moleculas similares a interferon beta.
|
WO2002070655A2
(en)
|
2001-03-02 |
2002-09-12 |
Zymogenetics, Inc. |
Mouse cytokine receptor
|
US7038015B2
(en)
*
|
2001-04-06 |
2006-05-02 |
Maxygen Holdings, Ltd. |
Interferon gamma polypeptide variants
|
US6958388B2
(en)
|
2001-04-06 |
2005-10-25 |
Maxygen, Aps |
Interferon gamma polypeptide variants
|
WO2002083166A1
(fr)
*
|
2001-04-10 |
2002-10-24 |
Santen Pharmaceutical Co., Ltd. |
Complexes de polymeres d'interferons et leur utilisation medicinale
|
DK1436003T3
(da)
|
2001-05-24 |
2010-03-15 |
Zymogenetics Inc |
TACI-immunoglobulin-fusionsproteiner
|
WO2003000278A1
(fr)
*
|
2001-06-22 |
2003-01-03 |
Kyowa Hakko Kogyo Co., Ltd. |
Onguents
|
MD2053C2
(ro)
*
|
2001-07-10 |
2003-07-31 |
Национальный Научно-Практический Центр Превентивной Медицины Министерства Здравоохранения Республики Молдова |
Remediu cu acţiune interferonogenă
|
WO2003018665A1
(en)
|
2001-08-22 |
2003-03-06 |
Bioartificial Gel Technologies Inc. |
Process for the preparation of activated polyethylene glycols
|
WO2003049760A1
(en)
*
|
2001-12-07 |
2003-06-19 |
Intermune, Inc. |
Compositions and method for treating hepatitis virus infection
|
KR100888371B1
(ko)
|
2002-01-17 |
2009-03-13 |
동아제약주식회사 |
가지 달린 고분자 유도체와 인터페론 결합체를 포함하는 항바이러스제
|
EP3669887A1
(en)
*
|
2002-01-18 |
2020-06-24 |
Biogen MA Inc. |
Polyalkylene polymer compounds and uses thereof
|
DE60315145T2
(de)
*
|
2002-03-13 |
2008-04-30 |
Beijing Jiankai Technology Co., Ltd. |
Hydrophiles polymerderivat mit y-verzweigung und herstellungsverfahren dafür; obige verbindung enthaltender medizinischer verbundwerkstoff
|
JP2005535575A
(ja)
*
|
2002-04-11 |
2005-11-24 |
ザイモジェネティクス インコーポレイティッド |
卵巣癌を治療するためのインターロイキン−24の使用法
|
EP2295455A1
(en)
|
2002-04-19 |
2011-03-16 |
ZymoGenetics, L.L.C. |
Cytokine receptor
|
WO2004000366A1
(en)
|
2002-06-21 |
2003-12-31 |
Novo Nordisk Health Care Ag |
Pegylated factor vii glycoforms
|
AU2003239774A1
(en)
*
|
2002-07-03 |
2004-01-23 |
Maxygen Holdings Ltd. |
Full-length interferon gamma polypeptide variants
|
AU2003258518B2
(en)
|
2002-07-24 |
2007-01-18 |
F. Hoffmann-La Roche Ag |
Polyalkylene glycol acid additives
|
MXPA05002477A
(es)
*
|
2002-09-05 |
2005-10-19 |
Gen Hospital Corp |
Asialo-interferones y el tratamiento de cancer de higado.
|
EP1549332A4
(en)
*
|
2002-09-05 |
2008-06-18 |
Gen Hospital Corp |
MODIFIED ASIALO-INTERFERONS AND USES THEREOF
|
CA2498062C
(en)
*
|
2002-09-27 |
2010-05-25 |
F. Hoffmann-La Roche Ag |
Conjugates of insulin-like growth factor binding protein-4 and poly(ethylene glycol)
|
US20040175359A1
(en)
*
|
2002-11-12 |
2004-09-09 |
Desjarlais John Rudolph |
Novel proteins with antiviral, antineoplastic, and/or immunomodulatory activity
|
US7314613B2
(en)
*
|
2002-11-18 |
2008-01-01 |
Maxygen, Inc. |
Interferon-alpha polypeptides and conjugates
|
EA008866B1
(ru)
*
|
2002-12-26 |
2007-08-31 |
Маунтин Вью Фамэсьютикэлс, Инк. |
ПОЛИМЕРНЫЙ КОНЪЮГАТ МОДИФИКАЦИЙ ИНТЕРФЕРОНА-β, ФАРМАЦЕВТИЧЕСКИЕ ПРОДУКТЫ НА ЕГО ОСНОВЕ И СПОСОБ ИХ ПОЛУЧЕНИЯ
|
KR101162908B1
(ko)
*
|
2002-12-26 |
2012-07-06 |
마운틴 뷰 파마슈티컬즈, 인크. |
수용체-결합 활성이 보존된, 사이토카인, 케모카인,성장인자, 폴리펩티드 호르몬 및 이들의 길항제의 중합체접합체
|
WO2004060406A2
(en)
*
|
2002-12-31 |
2004-07-22 |
Nektar Therapeutics Al, Corporation |
Polymeric reagents comprising a ketone or a related functional group
|
BRPI0407511A
(pt)
*
|
2003-02-19 |
2006-02-14 |
Pharmacia Corp |
ésteres de polietilenoglicol ativados
|
JP2006519235A
(ja)
*
|
2003-02-26 |
2006-08-24 |
インターミューン インコーポレイティッド |
ポリエチレングリコール修飾インターフェロン組成物およびその使用方法
|
WO2004078127A2
(en)
*
|
2003-02-28 |
2004-09-16 |
Intermune, Inc. |
Continuous delivery methods for treating hepatitis virus infection
|
CA2458085A1
(en)
|
2003-03-21 |
2004-09-21 |
F. Hoffmann-La Roche Ag |
Transcriptional activity assay
|
JP2007525188A
(ja)
|
2003-05-16 |
2007-09-06 |
インターミューン インコーポレイテッド |
合成ケモカイン受容体リガンドおよびその使用方法
|
JP4808157B2
(ja)
|
2003-08-07 |
2011-11-02 |
ザイモジェネティクス リミテッド ライアビリティ カンパニー |
Il−28およびil−29の均一な調製物
|
GB0320638D0
(en)
|
2003-09-03 |
2003-10-01 |
Novartis Ag |
Organic compounds
|
EP2263684A1
(en)
|
2003-10-10 |
2010-12-22 |
Novo Nordisk A/S |
IL-21 derivatives
|
CA2540858C
(en)
|
2003-10-14 |
2009-12-08 |
Intermune, Inc. |
Macrocyclic carboxylic acids and acylsulfonamides as inhibitors of hcv replication
|
EP2641611A3
(en)
|
2003-10-17 |
2013-12-18 |
Novo Nordisk A/S |
Combination therapy
|
US20050089952A1
(en)
*
|
2003-10-22 |
2005-04-28 |
Akzo Nobel N.V. |
Apparatuses and processes for increasing protein PEGylation reaction yields
|
US7407973B2
(en)
*
|
2003-10-24 |
2008-08-05 |
Intermune, Inc. |
Use of pirfenidone in therapeutic regimens
|
WO2005062949A2
(en)
*
|
2003-12-23 |
2005-07-14 |
Intermune, Inc. |
Method for treating hepatitis virus infection
|
GB0500020D0
(en)
|
2005-01-04 |
2005-02-09 |
Novartis Ag |
Organic compounds
|
NZ548256A
(en)
|
2004-02-02 |
2010-02-26 |
Ambrx Inc |
Modified human four helical bundle polypeptides and their uses
|
US7351787B2
(en)
*
|
2004-03-05 |
2008-04-01 |
Bioartificial Gel Technologies, Inc. |
Process for the preparation of activated polyethylene glycols
|
TW200611910A
(en)
*
|
2004-05-19 |
2006-04-16 |
Maxygen Inc |
Interferon-alpha polypeptides and conjugates
|
WO2005123113A2
(en)
*
|
2004-06-14 |
2005-12-29 |
Intermune, Inc. |
Interferon compositions and methods of use thereof
|
KR20070034512A
(ko)
*
|
2004-06-18 |
2007-03-28 |
암브룩스, 인코포레이티드 |
신규 항원-결합 폴리펩티드 및 이의 용도
|
KR20070039593A
(ko)
*
|
2004-07-21 |
2007-04-12 |
암브룩스, 인코포레이티드 |
비천연적으로 코딩된 아미노산을 이용한 생합성 폴리펩티드
|
AU2005266892B2
(en)
|
2004-07-29 |
2011-03-03 |
Bristol-Myers Squibb Company |
Use of IL-28 and IL-29 to treat cancer and autoimmune disorders
|
CN101039660B
(zh)
|
2004-08-12 |
2010-10-06 |
先灵公司 |
稳定的聚乙二醇化干扰素制剂
|
CA2581423A1
(en)
|
2004-09-23 |
2006-03-30 |
Vasgene Therapeutics, Inc. |
Polipeptide compounds for inhibiting angiogenesis and tumor growth
|
WO2006073846A2
(en)
|
2004-12-22 |
2006-07-13 |
Ambrx, Inc. |
Methods for expression and purification of recombinant human growth hormone
|
CN102719366B
(zh)
*
|
2004-12-22 |
2014-07-16 |
Ambrx公司 |
氨酰基-tRNA合成酶的组合物及其用途
|
CN103690936A
(zh)
|
2004-12-22 |
2014-04-02 |
Ambrx公司 |
经修饰的人类生长激素
|
BRPI0519170A8
(pt)
|
2004-12-22 |
2018-05-08 |
Ambrx Inc |
formulações de hormônio de crescimento humano que compreendem um aminoácido não naturalmente codificado
|
CA2596390A1
(en)
|
2005-02-08 |
2006-08-17 |
Zymogenetics, Inc. |
Anti-il-20, anti-il-22 and anti-il-22ra antibodies and binding partners and methods of using in inflammation
|
ATE515512T1
(de)
|
2005-05-12 |
2011-07-15 |
Zymogenetics Inc |
Zusammensetzungen und verfahren zur modulierung von immunreaktionen
|
CA2607651A1
(en)
*
|
2005-05-18 |
2007-04-19 |
Maxygen, Inc. |
Evolved interferon-alpha polypeptides
|
AU2006255122B2
(en)
*
|
2005-06-03 |
2010-10-21 |
Ambrx, Inc. |
Improved human interferon molecules and their uses
|
CA2611836A1
(en)
*
|
2005-06-13 |
2006-12-21 |
Nastech Pharmaceutical Company Inc. |
Transmucosal delivery of peptide derivatives
|
CN101242842A
(zh)
|
2005-06-17 |
2008-08-13 |
诺瓦提斯公司 |
Sanglifehrin在hcv中的用途
|
EP1893632B1
(en)
|
2005-06-17 |
2015-08-12 |
Novo Nordisk Health Care AG |
Selective reduction and derivatization of engineered factor vii proteins comprising at least one non-native cysteine
|
EP1901777A2
(en)
*
|
2005-06-20 |
2008-03-26 |
Pepgen Corporation |
Low-toxicity, long-circulating chimeras of human interferon-alpha analogs and interferon tau
|
US7695710B2
(en)
|
2005-06-20 |
2010-04-13 |
Pepgen Corporation |
Antitumor and antiviral combination therapies using low-toxicity, long-circulating human interferon-alpha analogs
|
AU2006263331B2
(en)
*
|
2005-06-29 |
2012-02-16 |
Yeda Research And Development Co. Ltd. At The Weizmann Institute Of Science |
Recombinant interferon alpha2 (IFNalpha2) mutants
|
EP2305697A3
(en)
|
2005-07-25 |
2011-07-27 |
Intermune, Inc. |
Macrocyclic inhibitors of Hepatitis C virus replication
|
CN103103238B
(zh)
*
|
2005-08-18 |
2016-08-10 |
Ambrx公司 |
一种在细胞中制造在特定位置处具有所选氨基酸的抗体或抗体片段多肽的方法
|
EP1931697B1
(en)
|
2005-09-28 |
2010-09-15 |
ZymoGenetics, Inc. |
Il-17a and il-17f antagonists and methods of using the same
|
NZ568135A
(en)
|
2005-10-11 |
2011-06-30 |
Array Biopharma Inc |
Macrocyclic compounds and methods for inhibiting hepatitis C viral replication
|
JP2009514814A
(ja)
*
|
2005-10-21 |
2009-04-09 |
シナジェバ・バイオファーマ・コーポレイション |
グリコール化およびグリコシル化された家禽類由来の治療用たんぱく質
|
US20080171696A1
(en)
*
|
2005-10-21 |
2008-07-17 |
Avigenics, Inc. |
Pharmacodynamically enhanced therapeutic proteins
|
AU2006311568B2
(en)
*
|
2005-11-08 |
2010-11-11 |
Ambrx, Inc. |
Accelerants for the modification of non-natural amino acids and non-natural amino acid polypeptides
|
AU2006315347A1
(en)
*
|
2005-11-16 |
2007-05-24 |
Ambrx, Inc. |
Methods and compositions comprising non-natural amino acids
|
KR101423898B1
(ko)
*
|
2005-12-14 |
2014-07-28 |
암브룩스, 인코포레이티드 |
비-천연 아미노산 및 폴리펩티드를 함유하는 조성물, 비-천연 아미노산 및 폴리펩티드를 포함하는 방법, 및 비-천연 아미노산 및 폴리펩티드의 용도
|
CA2636914C
(en)
|
2006-01-12 |
2016-08-09 |
Kuniaki Yoshioka |
Oral composition containing interferon-.alpha.
|
CN100475270C
(zh)
|
2006-01-20 |
2009-04-08 |
清华大学 |
一种治疗肿瘤的药物及其应用
|
CN101002945B
(zh)
|
2006-01-20 |
2012-09-05 |
清华大学 |
一种用于肿瘤治疗的新型复合物
|
EP2007789B1
(en)
|
2006-04-11 |
2015-05-20 |
Novartis AG |
Spirocyclic HCV/HIV inhibitors and their uses
|
US20080096819A1
(en)
*
|
2006-05-02 |
2008-04-24 |
Allozyne, Inc. |
Amino acid substituted molecules
|
EP2395099A3
(en)
*
|
2006-05-02 |
2012-05-16 |
Allozyne, Inc. |
Amino acid substituted molecules
|
BRPI0712008A2
(pt)
|
2006-05-24 |
2012-01-10 |
Novo Nordisk Healthcare Ag |
derivados e análogos de fix prolongados
|
WO2007137456A1
(fr)
|
2006-06-01 |
2007-12-06 |
Yun Cheng |
Peptide pour la prévention ou le traitement d'atteinte hépatique et son dérivé ainsi que son utilisation
|
CN1911447B
(zh)
*
|
2006-06-30 |
2010-05-12 |
复旦大学 |
转铁蛋白-聚乙二醇-药物分子复合物及其制备药物的用途
|
EP1886685A1
(en)
|
2006-08-11 |
2008-02-13 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods, uses and compositions for modulating replication of hcv through the farnesoid x receptor (fxr) activation or inhibition
|
CA2666814A1
(en)
*
|
2006-08-21 |
2008-05-29 |
United Therapeutics Corporation |
Combination therapy for treatment of viral infections
|
NZ574960A
(en)
*
|
2006-09-08 |
2012-02-24 |
Ambrx Inc |
Suppressor trna transcription in vertebrate cells
|
CA2663083A1
(en)
*
|
2006-09-08 |
2008-03-13 |
Ambrx, Inc. |
Modified human plasma polypeptide or fc scaffolds and their uses
|
WO2008030613A2
(en)
*
|
2006-09-08 |
2008-03-13 |
Ambrx, Inc. |
Hybrid suppressor trna for vertebrate cells
|
US8470332B2
(en)
|
2006-11-22 |
2013-06-25 |
Bristol-Myers Squibb Company |
Targeted therapeutics based on engineered proteins for tyrosine kinases receptors, including IGF-IR
|
CN101219219B
(zh)
|
2007-01-10 |
2013-02-13 |
北京普罗吉生物科技发展有限公司 |
包含血管抑素或其片段的复合物、其制备方法及应用
|
US20100144599A1
(en)
|
2007-02-02 |
2010-06-10 |
Bristol-Myers Squibb Company |
Vegf pathway blockade
|
WO2008121563A2
(en)
|
2007-03-30 |
2008-10-09 |
Ambrx, Inc. |
Modified fgf-21 polypeptides and their uses
|
NZ580686A
(en)
*
|
2007-05-02 |
2012-11-30 |
Ambrx Inc |
Modified interferon beta polypeptides and their uses
|
CA2707840A1
(en)
*
|
2007-08-20 |
2009-02-26 |
Allozyne, Inc. |
Amino acid substituted molecules
|
CA2698396C
(en)
*
|
2007-09-04 |
2014-01-21 |
Biosteed Gene Expression Tech. Co., Ltd. |
Interferon alpha2a modified by polyethylene glycol, the preparation and use thereof
|
CA2698173C
(en)
*
|
2007-09-04 |
2015-02-03 |
Biosteed Gene Expression Tech. Co., Ltd. |
Interferon alpha 2b modified by polyethylene glycol, the preparation and use thereof
|
AU2008308509B2
(en)
|
2007-10-04 |
2014-10-23 |
Zymogenetics, Inc. |
B7 family member zB7H6 and related compositions and methods
|
EP2212432A4
(en)
|
2007-10-22 |
2011-10-19 |
Schering Corp |
COMPLETELY HUMAN ANTI-VEGF ANTIBODIES AND USE PROCEDURES
|
NZ603812A
(en)
|
2007-11-20 |
2014-06-27 |
Ambrx Inc |
Modified insulin polypeptides and their uses
|
AU2008333131B2
(en)
|
2007-12-07 |
2013-10-24 |
Merck Serono S/A |
Humanized antibody molecules specific for IL-31
|
CN103694337B
(zh)
|
2008-02-08 |
2016-03-02 |
Ambrx公司 |
经修饰瘦素多肽和其用途
|
MX2010010953A
(es)
|
2008-04-03 |
2011-04-21 |
Biosteed Gene Expression Tech Co Ltd |
Hormona de crecimiento modificada con glicol de polietileno de doble cadena, metodo de preparacion y aplicación del a misma.
|
WO2009142773A2
(en)
|
2008-05-22 |
2009-11-26 |
Bristol-Myers Squibb Company |
Multivalent fibronectin based scaffold domain proteins
|
EP2623112B1
(en)
|
2008-06-27 |
2015-03-04 |
Zymogenetics, Inc. |
Soluble hybrid Fc gamma receptors and related methods
|
EP3225248B1
(en)
*
|
2008-07-23 |
2023-06-07 |
Ambrx, Inc. |
Modified bovine g-csf polypeptides and their uses
|
CA2737026C
(en)
|
2008-09-26 |
2019-12-24 |
Ambrx, Inc. |
Modified animal erythropoietin polypeptides and their uses
|
CA2738033C
(en)
*
|
2008-09-26 |
2019-11-26 |
Ambrx, Inc. |
Non-natural amino acid replication-dependent microorganisms and vaccines
|
EP3025727A1
(en)
|
2008-10-02 |
2016-06-01 |
The J. David Gladstone Institutes |
Methods of treating liver disease
|
CN102448458B
(zh)
|
2009-03-18 |
2015-07-22 |
小利兰·斯坦福大学理事会 |
治疗黄病毒科病毒感染的方法和组合物
|
US20110182850A1
(en)
|
2009-04-10 |
2011-07-28 |
Trixi Brandl |
Organic compounds and their uses
|
US8512690B2
(en)
|
2009-04-10 |
2013-08-20 |
Novartis Ag |
Derivatised proline containing peptide compounds as protease inhibitors
|
KR20180056805A
(ko)
|
2009-06-04 |
2018-05-29 |
노파르티스 아게 |
IgG 콘쥬게이션을 위한 자리의 확인 방법
|
EP2459211A1
(en)
|
2009-07-31 |
2012-06-06 |
Medtronic, Inc. |
Continuous subcutaneous administration of interferon- to hepatitis c infected patients
|
CN102596201A
(zh)
|
2009-10-30 |
2012-07-18 |
贝林格尔.英格海姆国际有限公司 |
包含BI201335、干扰素α和利巴韦林的HCV组合治疗的用药方案
|
MX349301B
(es)
|
2009-12-21 |
2017-07-21 |
Ambrx Inc |
Polipéptidos de somatotropina bovina modificados y sus usos.
|
CN104017063A
(zh)
|
2009-12-21 |
2014-09-03 |
Ambrx公司 |
经过修饰的猪促生长素多肽和其用途
|
JP2013528374A
(ja)
|
2010-05-10 |
2013-07-11 |
パーシード セラピューティクス リミテッド ライアビリティ カンパニー |
Vla4のポリペプチド阻害剤
|
US8765737B1
(en)
|
2010-05-11 |
2014-07-01 |
Demerx, Inc. |
Methods and compositions for preparing and purifying noribogaine
|
US8362007B1
(en)
|
2010-05-11 |
2013-01-29 |
Demerx, Inc. |
Substituted noribogaine
|
US9394294B2
(en)
|
2010-05-11 |
2016-07-19 |
Demerx, Inc. |
Methods and compositions for preparing and purifying noribogaine
|
EP2576615B1
(en)
|
2010-05-26 |
2016-03-30 |
Bristol-Myers Squibb Company |
Fibronectin based scaffold proteins having improved stability
|
CN102711871A
(zh)
|
2010-06-16 |
2012-10-03 |
麦德托尼克公司 |
用于稳定药物递送装置中的药物的阻尼系统
|
US8637648B1
(en)
|
2010-06-22 |
2014-01-28 |
Demerx, Inc. |
Compositions comprising noribogaine and an excipient to facilitate transport across the blood brain barrier
|
US9586954B2
(en)
|
2010-06-22 |
2017-03-07 |
Demerx, Inc. |
N-substituted noribogaine prodrugs
|
US8802832B2
(en)
|
2010-06-22 |
2014-08-12 |
Demerx, Inc. |
Compositions comprising noribogaine and an excipient to facilitate transport across the blood brain barrier
|
US8741891B1
(en)
|
2010-06-22 |
2014-06-03 |
Demerx, Inc. |
N-substituted noribogaine prodrugs
|
CN103096891A
(zh)
|
2010-06-24 |
2013-05-08 |
判米德有限公司 |
利用羟氯喹或羟氯喹和抗病毒剂的组合治疗丙型肝炎病毒相关疾病
|
RU2586296C2
(ru)
|
2010-07-23 |
2016-06-10 |
Демеркс, Инк. |
Композиции норибогаина
|
DK2605789T3
(da)
|
2010-08-17 |
2019-09-16 |
Ambrx Inc |
Modificerede relaxinpolypeptider og anvendelser deraf
|
US9567386B2
(en)
|
2010-08-17 |
2017-02-14 |
Ambrx, Inc. |
Therapeutic uses of modified relaxin polypeptides
|
TWI480288B
(zh)
|
2010-09-23 |
2015-04-11 |
Lilly Co Eli |
牛顆粒細胞群落刺激因子及其變體之調配物
|
CN103179974A
(zh)
|
2010-10-05 |
2013-06-26 |
诺华有限公司 |
丙型肝炎病毒感染的新疗法
|
US9011833B2
(en)
|
2010-10-08 |
2015-04-21 |
Novartis Ag |
Vitamin E formulations of sulfamide NS3 inhibitors
|
JP6110791B2
(ja)
|
2010-11-30 |
2017-04-05 |
ノバルティス アーゲー |
C型肝炎ウイルス感染症の新規治療
|
EP2481740B1
(en)
|
2011-01-26 |
2015-11-04 |
DemeRx, Inc. |
Methods and compositions for preparing noribogaine from voacangine
|
WO2012107589A1
(en)
|
2011-02-11 |
2012-08-16 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods and pharmaceutical compositions for the treatment and prevention of hcv infections
|
KR20140007927A
(ko)
|
2011-03-31 |
2014-01-20 |
노파르티스 아게 |
C형 간염 바이러스 감염을 치료하기 위한 알리스포리비르
|
MX2013011411A
(es)
|
2011-04-01 |
2014-04-14 |
Novartis Ag |
Tratamiento para infeccion por el virus de hepatitis b solo o en combinacion con el virus de hepatitis delta y enfermedades hepaticas asociadas.
|
MA35029B1
(fr)
|
2011-04-13 |
2014-04-03 |
Novartis Ag |
Traitement de l'infection par le virus de l'hépatite c avec l'alisporivir
|
EP2709669A1
(en)
|
2011-05-17 |
2014-03-26 |
Bristol-Myers Squibb Company |
Methods for maintaining pegylation of polypeptides
|
EP2709648A4
(en)
|
2011-05-19 |
2015-04-08 |
Geysen Hendrik M |
COMPOUNDS FOR BINDING TO THE ERYTHROPOIETIN RECEPTOR
|
KR20140054009A
(ko)
|
2011-07-01 |
2014-05-08 |
바이엘 인텔렉쳐 프로퍼티 게엠베하 |
릴랙신 융합 폴리펩타이드 및 그의 용도
|
EP2734640A1
(en)
|
2011-07-20 |
2014-05-28 |
INSERM - Institut National de la Santé et de la Recherche Médicale |
Methods for determining treatment response in patients infected with hcv genotype 4
|
AU2012299423A1
(en)
*
|
2011-08-25 |
2014-03-06 |
Nanogen Pharmaceutical Biotechnology |
Peg-interferon lambda 1 conjugates
|
US9617274B1
(en)
|
2011-08-26 |
2017-04-11 |
Demerx, Inc. |
Synthetic noribogaine
|
JP2014528947A
(ja)
|
2011-09-27 |
2014-10-30 |
ノバルティス アーゲー |
C型肝炎ウイルス感染症の治療のためのアリスポリビル
|
JP2015504038A
(ja)
|
2011-10-31 |
2015-02-05 |
ブリストル−マイヤーズ スクイブ カンパニーBristol−Myers Squibb Company |
低減した免疫原性を有するフィブロネクチン結合ドメイン
|
MX349036B
(es)
|
2011-12-06 |
2017-07-07 |
Univ Leland Stanford Junior |
Metodos y composiciones para tratar enfermedades virales.
|
EP2788003A4
(en)
|
2011-12-09 |
2015-05-27 |
Demerx Inc |
PHOSPHATESTER OF NORIBOGAIN
|
US9150584B2
(en)
|
2012-01-25 |
2015-10-06 |
Demerx, Inc. |
Indole and benzofuran fused isoquinuclidene derivatives and processes for preparing them
|
US8877921B2
(en)
|
2012-01-25 |
2014-11-04 |
Demerx, Inc. |
Synthetic voacangine
|
US8454947B1
(en)
|
2012-03-01 |
2013-06-04 |
Nanogen Pharmaceutical Biotechnology |
PEG-interferon lambda 1 conjugates
|
WO2013137869A1
(en)
|
2012-03-14 |
2013-09-19 |
Boehringer Ingelheim International Gmbh |
Combination therapy for treating hcv infection in an hcv-hiv coinfected patient population
|
JP2015512900A
(ja)
|
2012-03-28 |
2015-04-30 |
ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング |
特別な患者の遺伝子亜型分集団のhcv感染症を治療するための併用療法
|
EP2830663B1
(en)
|
2012-03-30 |
2019-02-06 |
Sorrento Therapeutics Inc. |
Fully human antibodies that bind to vegfr2
|
US9844582B2
(en)
|
2012-05-22 |
2017-12-19 |
Massachusetts Institute Of Technology |
Synergistic tumor treatment with extended-PK IL-2 and therapeutic agents
|
WO2013174988A1
(en)
|
2012-05-24 |
2013-11-28 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods for predicting and monitoring treatment response in hcv- and hcv/hiv-infected subjects
|
WO2013181634A2
(en)
|
2012-05-31 |
2013-12-05 |
Sorrento Therapeutics Inc. |
Antigen binding proteins that bind pd-l1
|
SI2859017T1
(sl)
|
2012-06-08 |
2019-05-31 |
Sutro Biopharma, Inc. |
Protitelesa, ki vsebujejo specifične nenaravne aminokislinske ostanke, postopki njihove priprave in postopki njihove uporabe
|
CA2877573A1
(en)
|
2012-06-21 |
2013-12-27 |
Sorrento Therapeutics, Inc. |
Antigen binding proteins that bind c-met
|
WO2013192596A2
(en)
|
2012-06-22 |
2013-12-27 |
Sorrento Therapeutics Inc. |
Antigen binding proteins that bind ccr2
|
EP2863955B1
(en)
|
2012-06-26 |
2016-11-23 |
Sutro Biopharma, Inc. |
Modified fc proteins comprising site-specific non-natural amino acid residues, conjugates of the same, methods of their preparation and methods of their use
|
ES2728864T3
(es)
|
2012-08-31 |
2019-10-29 |
Sutro Biopharma Inc |
Aminoácidos modificados que comprenden un grupo azido
|
US20140205566A1
(en)
|
2012-11-30 |
2014-07-24 |
Novartis Ag |
Cyclic nucleuoside derivatives and uses thereof
|
US9783535B2
(en)
|
2012-12-20 |
2017-10-10 |
Demerx, Inc. |
Substituted noribogaine
|
US9045481B2
(en)
|
2012-12-20 |
2015-06-02 |
Demerx, Inc. |
Substituted noribogaine
|
US8940728B2
(en)
|
2012-12-20 |
2015-01-27 |
Demerx, Inc. |
Substituted noribogaine
|
WO2014120891A2
(en)
|
2013-02-01 |
2014-08-07 |
Bristol-Myers Squibb Company |
Fibronectin based scaffold proteins
|
CN105683217B
(zh)
|
2013-05-31 |
2019-12-10 |
索伦托治疗有限公司 |
与pd-1结合的抗原结合蛋白
|
ES2865473T3
(es)
|
2013-07-10 |
2021-10-15 |
Sutro Biopharma Inc |
Anticuerpos que comprenden múltiples residuos de aminoácidos no naturales sitio-específicos, métodos para su preparación y métodos de uso
|
EP3055298B1
(en)
|
2013-10-11 |
2020-04-29 |
Sutro Biopharma, Inc. |
Modified amino acids comprising tetrazine functional groups, methods of preparation, and methods of their use
|
CN106535895B
(zh)
|
2014-05-01 |
2020-02-28 |
艾格尔峰生物制药有限公司 |
丁型肝炎病毒感染的治疗
|
US11311519B2
(en)
|
2014-05-01 |
2022-04-26 |
Eiger Biopharmaceuticals, Inc. |
Treatment of hepatitis delta virus infection
|
US10076512B2
(en)
|
2014-05-01 |
2018-09-18 |
Eiger Biopharmaceuticals, Inc. |
Treatment of hepatitis delta virus infection
|
US9388239B2
(en)
|
2014-05-01 |
2016-07-12 |
Consejo Nacional De Investigation Cientifica |
Anti-human VEGF antibodies with unusually strong binding affinity to human VEGF-A and cross reactivity to human VEGF-B
|
US9550789B2
(en)
|
2014-06-18 |
2017-01-24 |
Demerx, Inc. |
Halogenated indole and benzofuran derivatives of isoquinuclidene and processes for preparing them
|
AU2015301753B2
(en)
|
2014-08-12 |
2021-04-08 |
Massachusetts Institute Of Technology |
Synergistic tumor treatment with IL-2 and integrin-binding-Fc-fusion protein
|
WO2016025645A1
(en)
|
2014-08-12 |
2016-02-18 |
Massachusetts Institute Of Technology |
Synergistic tumor treatment with il-2, a therapeutic antibody, and an immune checkpoint blocker
|
AU2015305894A1
(en)
|
2014-08-22 |
2017-04-06 |
Sorrento Therapeutics, Inc. |
Antigen binding proteins that bind CXCR3
|
US9987241B2
(en)
|
2014-09-25 |
2018-06-05 |
The Board Of Regents Of The University Of Oklahoma |
Enzyme conjugate and prodrug cancer therapy
|
MX2017004947A
(es)
|
2014-10-24 |
2017-06-29 |
Bristol Myers Squibb Co |
Polipeptidos del factor de crecimiento de fibroblastos 2 (fgf-21) modificados y usos de los mismos.
|
SI3215193T1
(sl)
|
2014-11-06 |
2024-02-29 |
Pharmaessentia Corporation |
Dozirna shema za pegiliran interferon
|
US20180066229A1
(en)
*
|
2015-03-17 |
2018-03-08 |
Shinshu University |
Method for preparing dendritic cells via non-adhesive culture using ifn
|
HUE054068T2
(hu)
|
2015-04-21 |
2021-08-30 |
Eiger Biopharmaceuticals Inc |
Lonafarnibot és Ritonavirt tartalmazó gyógyszerkészítmények
|
EP3370759A1
(en)
|
2015-11-03 |
2018-09-12 |
H. Hoffnabb-La Roche Ag |
Combination therapy of an hbv capsid assembly inhibitor and an interferon
|
WO2017079009A1
(en)
|
2015-11-04 |
2017-05-11 |
Eiger Biopharmaceuticals, Inc. |
Treatment of hepatitis delta virus infection
|
CN109715821B
(zh)
|
2016-01-29 |
2022-09-06 |
索伦托药业有限公司 |
与pd-l1结合的抗原结合蛋白
|
WO2018087345A1
(en)
|
2016-11-14 |
2018-05-17 |
F. Hoffmann-La Roche Ag |
COMBINATION THERAPY OF AN HBsAg INHIBITOR, A NUCLEOS(T)IDE ANALOGUE AND AN INTERFERON
|
US10603358B2
(en)
|
2017-01-10 |
2020-03-31 |
Nodus Therapeutics |
Combination tumor treatment with an integrin-binding-Fc fusion protein and immune stimulator
|
US10350266B2
(en)
|
2017-01-10 |
2019-07-16 |
Nodus Therapeutics, Inc. |
Method of treating cancer with a multiple integrin binding Fc fusion protein
|
US20190374611A1
(en)
|
2017-01-18 |
2019-12-12 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods and pharmaceutical compositions for the treatment patients suffering from myeloproliferative disorders
|
KR102670432B1
(ko)
|
2017-02-08 |
2024-05-28 |
브리스톨-마이어스 스큅 컴퍼니 |
약동학적 인핸서를 포함하는 변형된 렐락신 폴리펩티드 및 그의 용도
|
WO2019020593A1
(en)
|
2017-07-25 |
2019-01-31 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
METHODS AND PHARMACEUTICAL COMPOSITIONS FOR MODULATION OF MONOCYTOPOISIS
|
WO2020032951A1
(en)
|
2018-08-09 |
2020-02-13 |
The Board Of Regents Of The University Of Oklahoma |
Antimalarial enzyme conjugates, kits containing same, and methods of producing and using same
|
US11485781B2
(en)
|
2017-08-17 |
2022-11-01 |
Massachusetts Institute Of Technology |
Multiple specificity binders of CXC chemokines
|
KR20210057124A
(ko)
|
2018-09-11 |
2021-05-20 |
암브룩스, 인코포레이티드 |
인터류킨-2 폴리펩타이드 접합체 및 그의 용도
|
JP2022502037A
(ja)
|
2018-09-28 |
2022-01-11 |
マサチューセッツ インスティテュート オブ テクノロジー |
コラーゲンに局在化される免疫調節分子およびその方法
|
AU2019361206A1
(en)
|
2018-10-19 |
2021-06-03 |
Ambrx, Inc. |
Interleukin-10 polypeptide conjugates, dimers thereof, and their uses
|
EP3914289A1
(en)
|
2019-01-23 |
2021-12-01 |
Massachusetts Institute of Technology |
Combination immunotherapy dosing regimen for immune checkpoint blockade
|
AU2020223031A1
(en)
|
2019-02-12 |
2021-08-19 |
Ambrx, Inc. |
Compositions containing, methods and uses of antibody-TLR agonist conjugates
|
JP2022540699A
(ja)
|
2019-07-18 |
2022-09-16 |
ウエヌイグレックオ・ファーマ |
インターフェロンの有害作用を減少させる方法
|
TW202146011A
(zh)
|
2020-03-05 |
2021-12-16 |
美商詹森藥物公司 |
治療b型肝炎病毒感染之組合療法
|
CN115243726A
(zh)
|
2020-03-11 |
2022-10-25 |
北京泰德制药股份有限公司 |
白介素-2多肽偶联物及其使用方法
|
WO2021228983A1
(en)
|
2020-05-13 |
2021-11-18 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
A pharmaceutical composition comprising an arsenic compound, an inductor of type-1 ifn and a protein kinase inhibitor for treating cancer
|
EP3912627B1
(en)
|
2020-05-20 |
2022-09-07 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Methods for the treatment of coronavirus infections
|
CA3185614A1
(en)
|
2020-06-22 |
2021-12-30 |
Janssen Pharmaceuticals, Inc. |
Compositions and methods for treatment of hepatitis d virus infection
|
EP4199968A1
(en)
|
2020-08-20 |
2023-06-28 |
Ambrx, Inc. |
Antibody-tlr agonist conjugates, methods and uses thereof
|
WO2022043496A2
(en)
|
2020-08-28 |
2022-03-03 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Use of mait cells as biomarkers and biotargets in covid-19
|
WO2022079205A1
(en)
|
2020-10-15 |
2022-04-21 |
INSERM (Institut National de la Santé et de la Recherche Médicale) |
Use of ifn-alpha polypeptides for the treatment of coronavirus infections
|
WO2022159414A1
(en)
|
2021-01-22 |
2022-07-28 |
University Of Rochester |
Erythropoietin for gastroinfestinal dysfunction
|
MX2023011480A
(es)
|
2021-04-03 |
2023-12-06 |
Ambrx Inc |
Conjugados anticuerpo anti-her2-fármaco y usos de estos.
|