KR101562549B1
(ko)
|
2005-05-10 |
2015-10-23 |
인사이트 홀딩스 코포레이션 |
인돌아민 2,3-디옥시게나제의 조절제 및 이의 사용방법
|
PE20110308A1
(es)
|
2008-07-08 |
2011-06-10 |
Incyte Corp |
1,2,5-oxadiazoles como inhibidores de indolamina 2,3-dioxigenasa
|
ME03300B
(me)
|
2012-06-13 |
2019-07-20 |
Incyte Holdings Corp |
Supsтituisana triciklična jedinjenja као inhibiтori fgfr
|
US8673972B2
(en)
|
2012-08-03 |
2014-03-18 |
Foundation Medicine, Inc. |
Human papilloma virus as predictor of cancer prognosis
|
EP2959013A2
(en)
|
2013-02-25 |
2015-12-30 |
Novartis AG |
Novel androgen receptor mutation
|
JP6435315B2
(ja)
|
2013-03-15 |
2018-12-05 |
ジー1、セラピューティクス、インコーポレイテッドG1 Therapeutics, Inc. |
高活性抗新生物薬及び抗増殖剤
|
RS59790B1
(sr)
|
2013-03-15 |
2020-02-28 |
G1 Therapeutics Inc |
Privremena zaštita normalnih ćelija tokom hemoterapije
|
ES2657451T3
(es)
|
2013-04-19 |
2018-03-05 |
Incyte Holdings Corporation |
Heterocíclicos bicíclicos como inhibidores del FGFR
|
PL3091008T3
(pl)
*
|
2013-12-31 |
2018-12-31 |
Xuanzhu Pharma Co., Ltd. |
Inhibitor kinazy i jego zastosowanie
|
US9949976B2
(en)
|
2013-12-31 |
2018-04-24 |
Xuanzhu Pharma Co., Ltd. |
Kinase inhibitor and use thereof
|
TWI558399B
(zh)
*
|
2014-02-26 |
2016-11-21 |
美國禮來大藥廠 |
癌症之組合療法
|
CN104910137B
(zh)
*
|
2014-03-10 |
2017-04-19 |
山东轩竹医药科技有限公司 |
Cdk激酶抑制剂
|
US10555931B2
(en)
|
2014-05-28 |
2020-02-11 |
Piramal Enterprises Limited |
Pharmaceutical combination for the treatment of cancer
|
TWI675028B
(zh)
*
|
2014-07-24 |
2019-10-21 |
美商貝達醫藥公司 |
做為週期素依賴型激酶(cdk)抑制劑之2-h-吲唑衍生物及其醫療用途
|
CN105294655B
(zh)
*
|
2014-07-26 |
2019-03-15 |
广东东阳光药业有限公司 |
Cdk类小分子抑制剂的化合物及其用途
|
WO2016040848A1
(en)
|
2014-09-12 |
2016-03-17 |
G1 Therapeutics, Inc. |
Treatment of rb-negative tumors using topoisomerase inhibitors in combination with cyclin dependent kinase 4/6 inhibitors
|
EP3191098A4
(en)
|
2014-09-12 |
2018-04-25 |
G1 Therapeutics, Inc. |
Combinations and dosing regimes to treat rb-positive tumors
|
SI3218005T1
(sl)
|
2014-11-12 |
2023-06-30 |
Seagen Inc. |
Z glikanom delujoče spojine, in postopki uporabe
|
TWI704151B
(zh)
*
|
2014-12-22 |
2020-09-11 |
美商美國禮來大藥廠 |
Erk抑制劑
|
CN105732615B
(zh)
*
|
2014-12-31 |
2018-05-01 |
山东轩竹医药科技有限公司 |
Cdk激酶抑制剂
|
CN104529904B
(zh)
*
|
2015-01-09 |
2016-08-31 |
苏州明锐医药科技有限公司 |
玻玛西尼的制备方法
|
ES2751669T3
(es)
|
2015-02-20 |
2020-04-01 |
Incyte Corp |
Heterociclos bicíclicos como inhibidores FGFR
|
MA41551A
(fr)
|
2015-02-20 |
2017-12-26 |
Incyte Corp |
Hétérocycles bicycliques utilisés en tant qu'inhibiteurs de fgfr4
|
BR112017019286B1
(pt)
*
|
2015-03-11 |
2023-02-14 |
Chia Tai Tianqing Pharmaceutical Group Co., Ltd. |
Derivados de 2h-pirazol substituídos ou um sal farmacêuticamente aceitável dos mesmos
|
TWI609687B
(zh)
|
2015-04-14 |
2018-01-01 |
美國禮來大藥廠 |
平滑肌肉瘤之標靶性治療
|
TWI696617B
(zh)
|
2015-04-28 |
2020-06-21 |
大陸商上海復尚慧創醫藥研究有限公司 |
特定蛋白質激酶抑制劑
|
JP6400196B2
(ja)
|
2015-05-29 |
2018-10-03 |
帝人ファーマ株式会社 |
ピリド[3,4−d]ピリミジン誘導体及びその薬学的に許容される塩
|
CN104892580B
(zh)
*
|
2015-06-17 |
2018-01-26 |
镇江圣安医药有限公司 |
一种新型苯并咪唑‑嘧啶胺衍生物、及其应用
|
CN106316935B
(zh)
*
|
2015-06-30 |
2019-03-26 |
正大天晴药业集团股份有限公司 |
一种Abemaciclib中间体的制备方法
|
CN105111191B
(zh)
*
|
2015-07-21 |
2018-06-08 |
上海皓元生物医药科技有限公司 |
一种用于合成cdk9抑制剂的关键中间体及其制备方法和用途
|
CN106467517B
(zh)
*
|
2015-08-14 |
2019-09-06 |
正大天晴药业集团股份有限公司 |
氘修饰的Abemaciclib衍生物
|
CN105153119B
(zh)
*
|
2015-09-11 |
2019-01-01 |
广州必贝特医药技术有限公司 |
吡啶嘧啶胺类化合物或吡啶吡啶胺类化合物及其应用
|
CN106608879A
(zh)
|
2015-10-27 |
2017-05-03 |
甘李药业股份有限公司 |
一种蛋白激酶抑制剂及其制备方法和医药用途
|
CA3002097A1
(en)
|
2015-11-12 |
2017-05-18 |
Siamab Therapeutics, Inc. |
Glycan-interacting compounds and methods of use
|
CN106810536A
(zh)
*
|
2015-11-30 |
2017-06-09 |
甘李药业股份有限公司 |
一种蛋白激酶抑制剂及其制备方法和医药用途
|
WO2017108781A1
(en)
*
|
2015-12-22 |
2017-06-29 |
Ratiopharm Gmbh |
Abemaciclib form iv
|
CN106928216A
(zh)
*
|
2015-12-31 |
2017-07-07 |
中国科学院上海药物研究所 |
具有erk激酶抑制活性的化合物、其制备方法和用途
|
JP6663021B2
(ja)
*
|
2015-12-31 |
2020-03-11 |
シャンハイ ファーマシューティカルズ ホールディング カンパニー,リミティド |
窒素含有縮合複素環化合物、製造方法、中間体、組成物および使用
|
TWI736578B
(zh)
*
|
2016-02-06 |
2021-08-21 |
大陸商上海複尚慧創醫藥研究有限公司 |
6-5元稠合唑環衍生物及其藥物組合物,以及作為藥物的應用
|
WO2017160568A1
(en)
|
2016-03-16 |
2017-09-21 |
Eli Lilly And Company |
Combination therapy comprising the cdk4/6 inhibitor necitumumab and the egfr inhibitor abemaciclib for use in treating cancer
|
WO2017161253A1
(en)
|
2016-03-18 |
2017-09-21 |
Tufts Medical Center |
Compositions and methods for treating and preventing metabolic disorders
|
CN107266421B
(zh)
*
|
2016-04-08 |
2020-12-04 |
正大天晴药业集团股份有限公司 |
取代的苯并咪唑类衍生物
|
CN107286134B
(zh)
*
|
2016-04-11 |
2019-04-12 |
上海勋和医药科技有限公司 |
2,4-二取代嘧啶衍生物作为cdk抑制剂及其应用
|
KR102418765B1
(ko)
|
2016-04-12 |
2022-07-08 |
일라이 릴리 앤드 캄파니 |
암 치료를 위한 Notch 및 CDK4/6 억제제의 조합 요법
|
CA3020918A1
(en)
|
2016-04-12 |
2017-10-19 |
Eli Lilly And Company |
Combination therapy with notch and pi3k/mtor inhibitors for use in treating cancer
|
CN108883182A
(zh)
|
2016-04-15 |
2018-11-23 |
伊莱利利公司 |
用于治疗套细胞淋巴瘤的雷莫芦单抗和abemaciclib的组合治疗
|
CN109071552B
(zh)
*
|
2016-04-22 |
2022-06-03 |
达纳-法伯癌症研究所公司 |
细胞周期蛋白依赖性激酶4/6(cdk4/6)通过cdk4/6抑制剂与e3连接酶配体的缀合的降解及使用方法
|
LT3622953T
(lt)
|
2016-05-17 |
2021-04-26 |
Scandion Oncology A/S |
Kombinuotas vėžio gydymas
|
WO2017200969A1
(en)
|
2016-05-20 |
2017-11-23 |
Eli Lilly And Company |
Combination therapy with notch and pd-1 or pd-l1 inhibitors
|
JP2019516767A
(ja)
*
|
2016-05-23 |
2019-06-20 |
イーライ リリー アンド カンパニー |
癌の治療のためのペンブロリズマブとアベマシクリブとの組合せ
|
WO2017205213A1
(en)
|
2016-05-23 |
2017-11-30 |
Eli Lilly And Company |
Combination therapy of abemaciclib and immune checkpoint modulators for use in the treatment of cancer
|
CN106008468B
(zh)
*
|
2016-06-07 |
2018-11-23 |
上海宣创生物科技有限公司 |
玻玛西尼a晶型、b晶型、c晶型及其制备方法
|
WO2018017410A1
(en)
|
2016-07-22 |
2018-01-25 |
Eli Lilly And Company |
Combination therapy of abemaciclib and a pi3 kinase/mtor dual inhibitor for use in the treatment of breast cancer
|
CN109803684B
(zh)
|
2016-08-23 |
2022-08-23 |
卫材 R&D 管理有限公司 |
用于治疗肝细胞癌的组合疗法
|
CN107793399A
(zh)
*
|
2016-09-07 |
2018-03-13 |
上海翰森生物医药科技有限公司 |
Cdk4/6抑制剂及其制备方法和应用
|
CN112225724B
(zh)
*
|
2016-09-07 |
2022-04-29 |
江苏豪森药业集团有限公司 |
苯并咪唑类化合物激酶抑制剂及其制备方法和应用
|
CN109689641B
(zh)
*
|
2016-09-09 |
2020-11-03 |
正大天晴药业集团股份有限公司 |
一种取代的2-氢-吡唑衍生物的晶型、盐型及其制备方法
|
CN107868082A
(zh)
*
|
2016-09-22 |
2018-04-03 |
上海宣创生物科技有限公司 |
玻玛西尼甲磺酸盐a晶型及其制备方法
|
WO2018063873A1
(en)
|
2016-09-27 |
2018-04-05 |
Eli Lilly And Company |
Combination therapy of abemaciclib and a pi3 kinase/mtor dual inhibitor for use in the treatment of pancreatic cancer
|
CA3039405A1
(en)
|
2016-10-12 |
2018-04-19 |
Eli Lilly And Company |
Targeted treatment of mature t-cell lymphoma
|
EP3528812B1
(en)
|
2016-10-20 |
2020-12-30 |
Pfizer Inc |
Palbociclib for treating pah
|
WO2018081204A1
(en)
*
|
2016-10-26 |
2018-05-03 |
Li George Y |
DEUTERATED N-(5-((4-ETHYLPIPERAZIN-1-YL)METHYL) PYRIDIN-2-YL)-5-FLUORO-4-(4-FLUORO-1-ISOPROPYL-2-METHYL-1H-BENZO[d]IMIDAZOL-6-YL)PYRIMIDIN-2-AMINE
|
CN106588884B
(zh)
*
|
2016-11-10 |
2019-04-09 |
浙江大学 |
2-多取代芳环-嘧啶类衍生物及制备和医药用途
|
EP3541847A4
(en)
|
2016-11-17 |
2020-07-08 |
Seattle Genetics, Inc. |
COMPOUNDS INTERACTING WITH GLYCANE AND METHODS OF USE
|
WO2018097297A1
(ja)
|
2016-11-28 |
2018-05-31 |
帝人ファーマ株式会社 |
ピリド[3,4-d]ピリミジン誘導体及びその薬学的に許容される塩
|
KR102513448B1
(ko)
|
2016-12-16 |
2023-03-23 |
씨스톤 파마슈티컬즈 |
Cdk4/6 억제제
|
ES2917377T3
(es)
*
|
2016-12-22 |
2022-07-08 |
Betta Pharmaceuticals Co Ltd |
Derivados de benzimidazol, procedimientos de preparación y utilizaciones de los mismos
|
CN108264512B
(zh)
*
|
2016-12-30 |
2022-05-03 |
上海医药集团股份有限公司 |
含氮稠杂环化合物、其制备方法、中间体、组合物和应用
|
ES2949364T3
(es)
|
2017-02-17 |
2023-09-28 |
Fred Hutchinson Cancer Center |
Terapias de combinación para el tratamiento de cánceres y trastornos autoinmunitarios relacionados con BCMA
|
GB201702947D0
(en)
*
|
2017-02-23 |
2017-04-12 |
Domainex Ltd |
Novel compounds
|
US10729692B2
(en)
*
|
2017-02-26 |
2020-08-04 |
Institute For Cancer Research |
Dual inhibition of CDK and HSP90 destabilize HIF1alpha and synergistically induces cancer cell death
|
MX2019010202A
(es)
|
2017-03-03 |
2019-10-02 |
Seattle Genetics Inc |
Compuestos que interactuan con glicano y metodos de uso.
|
KR102517650B1
(ko)
|
2017-03-16 |
2023-04-05 |
에자이 알앤드디 매니지먼트 가부시키가이샤 |
유방암의 치료를 위한 조합물 요법
|
JP2020517739A
(ja)
|
2017-05-02 |
2020-06-18 |
イーライ リリー アンド カンパニー |
リンパ節陽性の初期ホルモン受容体陽性かつヒト上皮成長因子受容体2陰性乳癌の補助治療のための内分泌療法とアベマシクリブとの組み合わせ
|
CN108794452B
(zh)
|
2017-05-05 |
2021-05-28 |
上海时莱生物技术有限公司 |
具有激酶抑制活性的化合物、其制备方法和用途
|
CN108929312A
(zh)
*
|
2017-05-22 |
2018-12-04 |
南开大学 |
具有cdk或hdac抑制活性的新型苯并杂环联嘧啶抑制剂
|
AR111960A1
(es)
|
2017-05-26 |
2019-09-04 |
Incyte Corp |
Formas cristalinas de un inhibidor de fgfr y procesos para su preparación
|
BR112019026483A2
(pt)
|
2017-06-16 |
2020-07-14 |
Beta Pharma, Inc. |
formulação farmacêutica de n-(2-(2-(dimetilamina)etoxi)-4-metoxi-5-((4-(1-metil-1h-indol-3-il)pirimidin-2-il)amina)fenil)acrilamida e seus sais
|
CN109503573A
(zh)
*
|
2017-09-14 |
2019-03-22 |
昆明圣加南生物科技有限公司 |
2-取代苯胺基嘧啶衍生物及其用途
|
CN107827875B
(zh)
*
|
2017-09-25 |
2021-07-09 |
文韬创新药物研究(北京)有限责任公司 |
一种苯并咪唑类衍生物作为周期蛋白依赖性激酶4/6抑制剂的应用
|
CN109761959B
(zh)
*
|
2017-11-09 |
2020-09-08 |
杭州科巢生物科技有限公司 |
一种Abemaciclib甲磺酸盐的合成方法
|
WO2019102492A1
(en)
|
2017-11-23 |
2019-05-31 |
Mylan Laboratories Limited |
Crystalline polymorphs of abemaciclib
|
CA3085366A1
(en)
|
2017-12-22 |
2019-06-27 |
Petra Pharma Corporation |
Aminopyridine derivatives as phosphatidylinositol phosphate kinase inhibitors
|
US10519136B2
(en)
|
2017-12-29 |
2019-12-31 |
Accutar Biotechnology |
Dual inhibitors of PARP1 and CDK
|
CA3087570A1
(en)
|
2018-01-08 |
2019-07-11 |
G1 Therapeutics, Inc. |
G1t38 superior dosage regimes
|
CA3088381A1
(en)
|
2018-01-29 |
2019-08-01 |
Beta Pharma, Inc. |
2h-indazole derivatives as cdk4 and cdk6 inhibitors and therapeutic uses thereof
|
CN110117272B
(zh)
*
|
2018-02-05 |
2021-12-10 |
上海翰森生物医药科技有限公司 |
细胞周期蛋白依赖性激酶抑制剂的盐及其晶型
|
WO2019161224A1
(en)
|
2018-02-15 |
2019-08-22 |
GiraFpharma LLC |
Heterocyclic compounds as kinase inhibitors
|
CN112384515A
(zh)
|
2018-02-27 |
2021-02-19 |
因赛特公司 |
作为a2a/a2b抑制剂的咪唑并嘧啶和三唑并嘧啶
|
CN108191747A
(zh)
*
|
2018-03-14 |
2018-06-22 |
盐城师范学院 |
一种Abemaciclib中间体的制备方法
|
WO2019195569A1
(en)
|
2018-04-05 |
2019-10-10 |
Johnson Matthey Public Limited Company |
Solid-state forms of abemaciclib, their use and preparation
|
CN111801323A
(zh)
*
|
2018-04-16 |
2020-10-20 |
杭州领业医药科技有限公司 |
玻玛西尼甲磺酸盐晶型及其制备方法和药物组合物
|
MX2020011294A
(es)
|
2018-04-26 |
2020-11-18 |
Pfizer |
Derivados de 2-amino-piridina o 2-amino-pirimidina como inhibidores de cinasa dependientes de ciclina.
|
JP2021523118A
(ja)
|
2018-05-04 |
2021-09-02 |
インサイト・コーポレイションIncyte Corporation |
Fgfr阻害剤の塩
|
CR20200590A
(es)
|
2018-05-04 |
2021-04-26 |
Incyte Corp |
Formas sólidas de un inhibidor de fgfr y procesos para prepararlas
|
MX2020011826A
(es)
*
|
2018-05-06 |
2021-01-15 |
Ayala Pharmaceuticals Inc |
Composiciones de combinacion que comprenden compuestos de bisfluoroalquil-1,4-benzodiazepinona y metodos de uso de las mismas.
|
MA52940A
(fr)
|
2018-05-18 |
2021-04-28 |
Incyte Corp |
Dérivés de pyrimidine fusionnés utilisés en tant qu'inhibiteurs de a2a/a2b
|
EP3818063A1
(en)
|
2018-07-05 |
2021-05-12 |
Incyte Corporation |
Fused pyrazine derivatives as a2a / a2b inhibitors
|
AU2019310595B2
(en)
*
|
2018-07-27 |
2022-11-24 |
1200 Pharma Llc |
CDK inhibitors and uses thereof
|
CN109232541B
(zh)
*
|
2018-09-30 |
2020-04-24 |
中国医学科学院放射医学研究所 |
脯氨酰羟化酶与组蛋白去乙酰化酶双重抑制剂及其制备方法和应用
|
US11066404B2
(en)
|
2018-10-11 |
2021-07-20 |
Incyte Corporation |
Dihydropyrido[2,3-d]pyrimidinone compounds as CDK2 inhibitors
|
CN109180589A
(zh)
*
|
2018-10-16 |
2019-01-11 |
武汉工程大学 |
玻玛西尼中间体的制备方法
|
WO2020108661A1
(zh)
*
|
2018-11-30 |
2020-06-04 |
杭州英创医药科技有限公司 |
作为cdk-hdac双通路抑制剂的杂环化合物
|
EP3903828A4
(en)
|
2018-12-21 |
2022-10-05 |
Daiichi Sankyo Company, Limited |
COMBINATION OF AN ANTIBODY-DRUG CONJUGATE AND A KINASE INHIBITOR
|
TWI829857B
(zh)
|
2019-01-29 |
2024-01-21 |
美商英塞特公司 |
作為a2a / a2b抑制劑之吡唑并吡啶及三唑并吡啶
|
SG11202108004VA
(en)
*
|
2019-01-29 |
2021-08-30 |
Beta Pharma Inc |
2h-indazole derivatives as therapeutic agents for brain cancers and brain metastases
|
EP3923949A1
(en)
|
2019-02-15 |
2021-12-22 |
Incyte Corporation |
Cyclin-dependent kinase 2 biomarkers and uses thereof
|
US11384083B2
(en)
|
2019-02-15 |
2022-07-12 |
Incyte Corporation |
Substituted spiro[cyclopropane-1,5′-pyrrolo[2,3-d]pyrimidin]-6′(7′h)-ones as CDK2 inhibitors
|
TW202100520A
(zh)
|
2019-03-05 |
2021-01-01 |
美商英塞特公司 |
作為cdk2 抑制劑之吡唑基嘧啶基胺化合物
|
US11628162B2
(en)
|
2019-03-08 |
2023-04-18 |
Incyte Corporation |
Methods of treating cancer with an FGFR inhibitor
|
WO2020205560A1
(en)
|
2019-03-29 |
2020-10-08 |
Incyte Corporation |
Sulfonylamide compounds as cdk2 inhibitors
|
WO2020223469A1
(en)
|
2019-05-01 |
2020-11-05 |
Incyte Corporation |
N-(1-(methylsulfonyl)piperidin-4-yl)-4,5-di hydro-1h-imidazo[4,5-h]quinazolin-8-amine derivatives and related compounds as cyclin-dependent kinase 2 (cdk2) inhibitors for treating cancer
|
WO2020223558A1
(en)
|
2019-05-01 |
2020-11-05 |
Incyte Corporation |
Tricyclic amine compounds as cdk2 inhibitors
|
MA55909A
(fr)
*
|
2019-05-05 |
2022-03-16 |
Qilu Regor Therapeutics Inc |
Inhibiteurs de cdk
|
US11591329B2
(en)
|
2019-07-09 |
2023-02-28 |
Incyte Corporation |
Bicyclic heterocycles as FGFR inhibitors
|
EP4007602A1
(en)
|
2019-08-01 |
2022-06-08 |
Incyte Corporation |
A dosing regimen for an ido inhibitor
|
WO2021030843A1
(en)
|
2019-08-13 |
2021-02-18 |
Johnson Matthey Public Limited Company |
Solid-state forms of abemaciclib, their use and preparation
|
CR20220066A
(es)
|
2019-08-14 |
2022-11-28 |
Incyte Corp |
Compuestos de imidazolil pirimidinilamina como inhibidores de cdk2
|
CN115298177A
(zh)
|
2019-10-11 |
2022-11-04 |
因赛特公司 |
作为cdk2抑制剂的双环胺
|
IL291901A
(en)
|
2019-10-14 |
2022-06-01 |
Incyte Corp |
Bicyclyl heterocycles as fgr suppressors
|
US11566028B2
(en)
|
2019-10-16 |
2023-01-31 |
Incyte Corporation |
Bicyclic heterocycles as FGFR inhibitors
|
CN110540535B
(zh)
*
|
2019-10-23 |
2020-07-31 |
上海再启生物技术有限公司 |
适合放大制备4-(6-氨基吡啶-3-基)取代哌啶的工艺方法
|
JP2023505258A
(ja)
|
2019-12-04 |
2023-02-08 |
インサイト・コーポレイション |
Fgfr阻害剤としての三環式複素環
|
JP2023505257A
(ja)
|
2019-12-04 |
2023-02-08 |
インサイト・コーポレイション |
Fgfr阻害剤の誘導体
|
CA3161892A1
(en)
|
2019-12-23 |
2021-07-01 |
Jie Fan |
Combinations of estrogen receptor degraders and cyclin-dependent kinase inhibitors for treating cancer
|
IL296065A
(en)
|
2020-03-06 |
2022-10-01 |
Incyte Corp |
Combined treatment including axl/mer and pd-1/pd-l1 inhibitors
|
EP4126244A4
(en)
*
|
2020-03-27 |
2024-03-27 |
Jiangsu Alphamab Biopharmaceuticals Co Ltd |
COMBINATION OF ANTI-HER2 ANTIBODIES AND CDK INHIBITORS FOR TUMOR TREATMENT
|
CR20220584A
(es)
|
2020-04-16 |
2023-02-15 |
Incyte Corp |
Inhibidores de kras tricíclicos fusionados
|
US11739102B2
(en)
|
2020-05-13 |
2023-08-29 |
Incyte Corporation |
Fused pyrimidine compounds as KRAS inhibitors
|
US10988479B1
(en)
|
2020-06-15 |
2021-04-27 |
G1 Therapeutics, Inc. |
Morphic forms of trilaciclib and methods of manufacture thereof
|
EP4159728A1
(en)
*
|
2020-06-22 |
2023-04-05 |
Chia Tai Tianqing Pharmaceutical Group Co., Ltd. |
Preparation method for cdk4/6 inhibitor
|
CN113880814B
(zh)
*
|
2020-07-01 |
2024-01-05 |
杭州百诚医药科技股份有限公司 |
一种嘧啶胺类化合物及应用
|
CN113880809B
(zh)
*
|
2020-07-03 |
2022-10-18 |
盛世泰科生物医药技术(苏州)有限公司 |
一种嘧啶类衍生物及其制备方法和应用
|
WO2022047093A1
(en)
|
2020-08-28 |
2022-03-03 |
Incyte Corporation |
Vinyl imidazole compounds as inhibitors of kras
|
CN116113628A
(zh)
*
|
2020-08-31 |
2023-05-12 |
甘李药业股份有限公司 |
一种含cdk4/6抑制剂的药物组合物
|
CN112028834B
(zh)
*
|
2020-09-11 |
2022-03-29 |
济南悟通生物科技有限公司 |
一种阿贝西利的中间体的合成方法
|
US11767320B2
(en)
|
2020-10-02 |
2023-09-26 |
Incyte Corporation |
Bicyclic dione compounds as inhibitors of KRAS
|
CN114539225B
(zh)
*
|
2020-11-11 |
2024-02-20 |
上海拓界生物医药科技有限公司 |
2-氨基-嘧啶类化合物
|
CN112390793B
(zh)
*
|
2021-01-19 |
2021-04-27 |
中国药科大学 |
Cdk6/dyrk2双靶点抑制剂及其制备方法和应用
|
WO2022155941A1
(en)
|
2021-01-25 |
2022-07-28 |
Qilu Regor Therapeutics Inc. |
Cdk2 inhibitors
|
WO2022162122A1
(en)
|
2021-01-29 |
2022-08-04 |
Biotx.Ai Gmbh |
Genetically verified netosis inhibitor for use in the treatment of a sars-cov2 infection
|
CN114907343A
(zh)
*
|
2021-02-10 |
2022-08-16 |
上海医药集团股份有限公司 |
含氮稠杂环化合物的盐、晶型及其制备方法、药物组合物和用途
|
WO2022206888A1
(en)
|
2021-03-31 |
2022-10-06 |
Qilu Regor Therapeutics Inc. |
Cdk2 inhibitors and use thereof
|
JP2024513575A
(ja)
|
2021-04-12 |
2024-03-26 |
インサイト・コーポレイション |
Fgfr阻害剤及びネクチン-4標的化剤を含む併用療法
|
CN117222636A
(zh)
*
|
2021-04-12 |
2023-12-12 |
甘李药业股份有限公司 |
作为cdk4/6抑制剂的氘代化合物
|
CA3220274A1
(en)
|
2021-06-09 |
2022-12-15 |
Incyte Corporation |
Tricyclic heterocycles as fgfr inhibitors
|
TW202313610A
(zh)
|
2021-06-09 |
2023-04-01 |
美商英塞特公司 |
作為fgfr抑制劑之三環雜環
|
CN113248500B
(zh)
*
|
2021-06-10 |
2021-10-19 |
中国药科大学 |
氮杂吲哚嘧啶胺杂环化合物及其制备方法和应用
|
US11981671B2
(en)
|
2021-06-21 |
2024-05-14 |
Incyte Corporation |
Bicyclic pyrazolyl amines as CDK2 inhibitors
|
TW202317565A
(zh)
|
2021-07-07 |
2023-05-01 |
美商英塞特公司 |
作為kras抑制劑的三環化合物
|
EP4370515A1
(en)
|
2021-07-14 |
2024-05-22 |
Incyte Corporation |
Tricyclic compounds as inhibitors of kras
|
US20230174555A1
(en)
|
2021-08-31 |
2023-06-08 |
Incyte Corporation |
Naphthyridine compounds as inhibitors of kras
|
WO2023040914A1
(zh)
*
|
2021-09-14 |
2023-03-23 |
甘李药业股份有限公司 |
一种cdk4/6抑制剂的医药用途
|
US20230151005A1
(en)
|
2021-09-21 |
2023-05-18 |
Incyte Corporation |
Hetero-tricyclic compounds as inhibitors of kras
|
CA3234375A1
(en)
|
2021-10-01 |
2023-04-06 |
Incyte Corporation |
Pyrazoloquinoline kras inhibitors
|
US11939328B2
(en)
|
2021-10-14 |
2024-03-26 |
Incyte Corporation |
Quinoline compounds as inhibitors of KRAS
|
WO2023091746A1
(en)
|
2021-11-22 |
2023-05-25 |
Incyte Corporation |
Combination therapy comprising an fgfr inhibitor and a kras inhibitor
|
US20230203010A1
(en)
|
2021-12-03 |
2023-06-29 |
Incyte Corporation |
Bicyclic amine cdk12 inhibitors
|
WO2023107428A1
(en)
*
|
2021-12-07 |
2023-06-15 |
The Regents Of The University Of California |
Methods for treating traumatic brain injury
|
WO2023107525A1
(en)
|
2021-12-10 |
2023-06-15 |
Eli Lilly And Company |
Cdk4 and 6 inhibitor in combination with fulvestrant for the treatment of hormone receptor-positive, human epidermal growth factor receptor 2-negative advanced or metastatic breast cancer in patients previously treated with a cdk4 and 6 inhibitor
|
US20230183251A1
(en)
|
2021-12-10 |
2023-06-15 |
Incyte Corporation |
Bicyclic amines as cdk12 inhibitors
|
US11976073B2
(en)
|
2021-12-10 |
2024-05-07 |
Incyte Corporation |
Bicyclic amines as CDK2 inhibitors
|
WO2023114225A1
(en)
|
2021-12-14 |
2023-06-22 |
Board Of Regents, The University Of Texas System |
Pharmaceutical combination comprising abemaciclib and a pi3k and/or a mtor inhibitor for the treatment of mantle cell lymphoma
|
WO2023114264A1
(en)
|
2021-12-15 |
2023-06-22 |
Eli Lilly And Company |
Combination for treatment of high-risk metastatic hormone-sensitive prostate cancer
|
WO2023109875A1
(en)
*
|
2021-12-16 |
2023-06-22 |
Edigene Therapeutics (Beijing) Inc. |
Biomarkers for colorectal cancer treatment
|
WO2023122134A1
(en)
|
2021-12-22 |
2023-06-29 |
Incyte Corporation |
Salts and solid forms of an fgfr inhibitor and processes of preparing thereof
|
WO2023116884A1
(en)
|
2021-12-24 |
2023-06-29 |
Qilu Regor Therapeutics Inc. |
Cdk2 inhibitors and use thereof
|
WO2023168686A1
(en)
|
2022-03-11 |
2023-09-14 |
Qilu Regor Therapeutics Inc. |
Substituted cyclopentanes as cdk2 inhibitors
|
US20230279004A1
(en)
|
2022-03-07 |
2023-09-07 |
Incyte Corporation |
Solid forms, salts, and processes of preparation of a cdk2 inhibitor
|
CN115057845B
(zh)
*
|
2022-06-14 |
2024-05-03 |
山东罗欣药业集团恒欣药业有限公司 |
一种阿贝西利的制备方法
|
WO2023250430A1
(en)
|
2022-06-22 |
2023-12-28 |
Incyte Corporation |
Bicyclic amine cdk12 inhibitors
|
US20240101557A1
(en)
|
2022-07-11 |
2024-03-28 |
Incyte Corporation |
Fused tricyclic compounds as inhibitors of kras g12v mutants
|
WO2024032751A1
(zh)
*
|
2022-08-12 |
2024-02-15 |
正大天晴药业集团股份有限公司 |
一种取代的2-氢-吡唑衍生物的晶型及其制备方法
|
WO2024049926A1
(en)
|
2022-08-31 |
2024-03-07 |
Arvinas Operations, Inc. |
Dosage regimens of estrogen receptor degraders
|
JP2024067010A
(ja)
|
2022-11-02 |
2024-05-16 |
ペトラ・ファーマ・コーポレイション |
疾患の治療用のホスホイノシチド3-キナーゼ(pi3k)のアロステリッククロメノン阻害剤
|
WO2024100236A1
(en)
|
2022-11-11 |
2024-05-16 |
Astrazeneca Ab |
Combination therapies for the treatment of cancer
|
CN117298115A
(zh)
*
|
2022-11-18 |
2023-12-29 |
轩竹生物科技股份有限公司 |
CDKs抑制剂的药物组合物及制备方法
|