ECSP066448A - Péptidos macrocíclicos activos contra el virus de la hepatits c - Google Patents
Péptidos macrocíclicos activos contra el virus de la hepatits cInfo
- Publication number
- ECSP066448A ECSP066448A EC2006006448A ECSP066448A ECSP066448A EC SP066448 A ECSP066448 A EC SP066448A EC 2006006448 A EC2006006448 A EC 2006006448A EC SP066448 A ECSP066448 A EC SP066448A EC SP066448 A ECSP066448 A EC SP066448A
- Authority
- EC
- Ecuador
- Prior art keywords
- hepatits
- virus
- macrocyclic peptides
- peptides against
- active macrocyclic
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/08—Tripeptides
- C07K5/0827—Tripeptides containing heteroatoms different from O, S, or N
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/08—Tripeptides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/08—Tripeptides
- C07K5/0802—Tripeptides with the first amino acid being neutral
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/08—Tripeptides
- C07K5/0802—Tripeptides with the first amino acid being neutral
- C07K5/0812—Tripeptides with the first amino acid being neutral and aromatic or cycloaliphatic
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Genetics & Genomics (AREA)
- General Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Virology (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Peptides Or Proteins (AREA)
Abstract
Compuestos de la fórmula I: (I)en la que D, R4, R3, L0, L1, L2, R2 y RC son como se definen en esta memoria; o una de sus sales farmacéuticamente aceptables, útiles como inhibidores de la proteasa NS3 del VHC.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US50483903P | 2003-09-22 | 2003-09-22 |
Publications (1)
Publication Number | Publication Date |
---|---|
ECSP066448A true ECSP066448A (es) | 2006-09-18 |
Family
ID=34375541
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EC2006006448A ECSP066448A (es) | 2003-09-22 | 2006-03-22 | Péptidos macrocíclicos activos contra el virus de la hepatits c |
Country Status (22)
Country | Link |
---|---|
US (2) | US7642235B2 (es) |
EP (1) | EP1673385B1 (es) |
JP (2) | JP4704342B2 (es) |
KR (1) | KR20060094083A (es) |
CN (1) | CN1856502A (es) |
AR (1) | AR045938A1 (es) |
AT (1) | ATE500264T1 (es) |
AU (1) | AU2004274051A1 (es) |
BR (1) | BRPI0414571A (es) |
CA (1) | CA2536182C (es) |
DE (1) | DE602004031645D1 (es) |
EA (1) | EA200600498A1 (es) |
EC (1) | ECSP066448A (es) |
ES (1) | ES2361997T3 (es) |
IL (1) | IL174403A0 (es) |
MX (1) | MXPA06003141A (es) |
NO (1) | NO20061767L (es) |
PE (1) | PE20050431A1 (es) |
RS (1) | RS20060197A (es) |
TW (1) | TW200521144A (es) |
UY (1) | UY28525A1 (es) |
WO (1) | WO2005028501A1 (es) |
Families Citing this family (125)
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SV2003000617A (es) | 2000-08-31 | 2003-01-13 | Lilly Co Eli | Inhibidores de la proteasa peptidomimetica ref. x-14912m |
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US20050075279A1 (en) * | 2002-10-25 | 2005-04-07 | Boehringer Ingelheim International Gmbh | Macrocyclic peptides active against the hepatitis C virus |
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EA200600498A1 (ru) | 2003-09-22 | 2006-10-27 | Бёрингер Ингельхайм Интернациональ Гмбх | Макроциклические пептиды, проявляющие противовирусную активность в отношении вируса гепатита с |
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-
2004
- 2004-09-20 EA EA200600498A patent/EA200600498A1/ru unknown
- 2004-09-20 AU AU2004274051A patent/AU2004274051A1/en not_active Abandoned
- 2004-09-20 RS YUP-2006/0197A patent/RS20060197A/sr unknown
- 2004-09-20 CN CNA2004800274171A patent/CN1856502A/zh active Pending
- 2004-09-20 US US10/945,518 patent/US7642235B2/en active Active
- 2004-09-20 PE PE2004000913A patent/PE20050431A1/es not_active Application Discontinuation
- 2004-09-20 ES ES04761821T patent/ES2361997T3/es active Active
- 2004-09-20 AT AT04761821T patent/ATE500264T1/de active
- 2004-09-20 MX MXPA06003141A patent/MXPA06003141A/es not_active Application Discontinuation
- 2004-09-20 EP EP04761821A patent/EP1673385B1/en active Active
- 2004-09-20 KR KR1020067007658A patent/KR20060094083A/ko not_active Application Discontinuation
- 2004-09-20 CA CA2536182A patent/CA2536182C/en not_active Expired - Fee Related
- 2004-09-20 UY UY28525A patent/UY28525A1/es not_active Application Discontinuation
- 2004-09-20 JP JP2006526494A patent/JP4704342B2/ja not_active Expired - Fee Related
- 2004-09-20 WO PCT/CA2004/001658 patent/WO2005028501A1/en active Application Filing
- 2004-09-20 DE DE602004031645T patent/DE602004031645D1/de active Active
- 2004-09-20 BR BRPI0414571-2A patent/BRPI0414571A/pt not_active IP Right Cessation
- 2004-09-21 TW TW093128495A patent/TW200521144A/zh unknown
- 2004-09-22 AR ARP040103399A patent/AR045938A1/es unknown
-
2006
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- 2006-03-22 EC EC2006006448A patent/ECSP066448A/es unknown
- 2006-04-21 NO NO20061767A patent/NO20061767L/no not_active Application Discontinuation
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2009
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- 2010-07-08 JP JP2010156015A patent/JP2011006420A/ja not_active Withdrawn
Also Published As
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EA200600498A1 (ru) | 2006-10-27 |
RS20060197A (en) | 2008-09-29 |
EP1673385A4 (en) | 2006-10-04 |
AU2004274051A1 (en) | 2005-03-31 |
EP1673385A1 (en) | 2006-06-28 |
JP4704342B2 (ja) | 2011-06-15 |
JP2007529411A (ja) | 2007-10-25 |
US20050080005A1 (en) | 2005-04-14 |
NO20061767L (no) | 2006-06-16 |
KR20060094083A (ko) | 2006-08-28 |
CN1856502A (zh) | 2006-11-01 |
JP2011006420A (ja) | 2011-01-13 |
DE602004031645D1 (de) | 2011-04-14 |
BRPI0414571A (pt) | 2006-11-07 |
AR045938A1 (es) | 2005-11-16 |
TW200521144A (en) | 2005-07-01 |
PE20050431A1 (es) | 2005-07-19 |
IL174403A0 (en) | 2006-08-01 |
WO2005028501A1 (en) | 2005-03-31 |
ES2361997T3 (es) | 2011-06-27 |
CA2536182A1 (en) | 2005-03-31 |
US7642235B2 (en) | 2010-01-05 |
MXPA06003141A (es) | 2006-06-05 |
UY28525A1 (es) | 2005-04-29 |
CA2536182C (en) | 2012-07-24 |
US20100028300A1 (en) | 2010-02-04 |
EP1673385B1 (en) | 2011-03-02 |
ATE500264T1 (de) | 2011-03-15 |
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