EA200801538A1 - Лечение диабета 2 типа комбинацией ингибитора дипептидилпептидазы iv (dpiv) и метформина или тиазолидиндиона - Google Patents

Лечение диабета 2 типа комбинацией ингибитора дипептидилпептидазы iv (dpiv) и метформина или тиазолидиндиона

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Publication number
EA200801538A1
EA200801538A1 EA200801538A EA200801538A EA200801538A1 EA 200801538 A1 EA200801538 A1 EA 200801538A1 EA 200801538 A EA200801538 A EA 200801538A EA 200801538 A EA200801538 A EA 200801538A EA 200801538 A1 EA200801538 A1 EA 200801538A1
Authority
EA
Eurasian Patent Office
Prior art keywords
dpiv
inhibitor
tiazolidindion
metformine
dipeptidylpeptidase
Prior art date
Application number
EA200801538A
Other languages
English (en)
Other versions
EA017084B1 (ru
Inventor
Джонатан Рэчмэн
Original Assignee
Прозидион Лимитед
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=35841111&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=EA200801538(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Прозидион Лимитед filed Critical Прозидион Лимитед
Publication of EA200801538A1 publication Critical patent/EA200801538A1/ru
Publication of EA017084B1 publication Critical patent/EA017084B1/ru

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425—Thiazoles
    • A61K31/426—1,3-Thiazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/155—Amidines (), e.g. guanidine (H2N—C(=NH)—NH2), isourea (N=C(OH)—NH2), isothiourea (—N=C(SH)—NH2)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/48—Drugs for disorders of the endocrine system of the pancreatic hormones
    • A61P5/50—Drugs for disorders of the endocrine system of the pancreatic hormones for increasing or potentiating the activity of insulin

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  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Diabetes (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Endocrinology (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Emergency Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

Данное изобретение относится к терапевтическому способу контроля гликемии, в частности, к способу лечения диабета 2 типа, включающему введение ингибитора дипептидилпептидазы IV (DPIV) совместно с метформином или тиазолидиндионом.
EA200801538A 2005-12-23 2006-12-22 Способ лечения диабета 2 типа комбинацией ингибитора дипептидилпептидазы iv (dpiv) и метформина или тиазолидиндиона EA017084B1 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB0526291.0A GB0526291D0 (en) 2005-12-23 2005-12-23 Therapeutic method
PCT/GB2006/050475 WO2007072083A1 (en) 2005-12-23 2006-12-22 Treatment of type 2 diabetes with a combination of dpiv inhibitor and metformin or thiazolidinedione

Publications (2)

Publication Number Publication Date
EA200801538A1 true EA200801538A1 (ru) 2008-12-30
EA017084B1 EA017084B1 (ru) 2012-09-28

Family

ID=35841111

Family Applications (1)

Application Number Title Priority Date Filing Date
EA200801538A EA017084B1 (ru) 2005-12-23 2006-12-22 Способ лечения диабета 2 типа комбинацией ингибитора дипептидилпептидазы iv (dpiv) и метформина или тиазолидиндиона

Country Status (28)

Country Link
US (3) US20100216800A1 (ru)
EP (1) EP1965783B1 (ru)
JP (2) JP2009520801A (ru)
KR (1) KR20080080220A (ru)
CN (1) CN101365434A (ru)
AU (1) AU2006327974B2 (ru)
BR (1) BRPI0620450A2 (ru)
CA (1) CA2634379C (ru)
CY (1) CY1114401T1 (ru)
DK (1) DK1965783T3 (ru)
EA (1) EA017084B1 (ru)
ES (1) ES2427822T3 (ru)
GB (1) GB0526291D0 (ru)
HK (1) HK1121074A1 (ru)
HR (1) HRP20130880T1 (ru)
IL (1) IL192257A0 (ru)
MA (1) MA30085B1 (ru)
MX (1) MX2008008250A (ru)
NO (1) NO20082790L (ru)
NZ (1) NZ569427A (ru)
PL (1) PL1965783T3 (ru)
PT (1) PT1965783E (ru)
RS (1) RS52942B (ru)
SG (1) SG186610A1 (ru)
SI (1) SI1965783T1 (ru)
UA (1) UA100111C2 (ru)
WO (1) WO2007072083A1 (ru)
ZA (1) ZA200806200B (ru)

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US11065215B2 (en) 2011-01-07 2021-07-20 Anji Pharma (Us) Llc Biguanide compositions and methods of treating metabolic disorders
US11759441B2 (en) 2011-01-07 2023-09-19 Anji Pharmaceuticals Inc. Biguanide compositions and methods of treating metabolic disorders
US11974971B2 (en) 2011-01-07 2024-05-07 Anji Pharmaceuticals Inc. Compositions and methods for treating metabolic disorders

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AR071175A1 (es) 2008-04-03 2010-06-02 Boehringer Ingelheim Int Composicion farmaceutica que comprende un inhibidor de la dipeptidil-peptidasa-4 (dpp4) y un farmaco acompanante
UY32030A (es) 2008-08-06 2010-03-26 Boehringer Ingelheim Int "tratamiento para diabetes en pacientes inapropiados para terapia con metformina"
KR20190016601A (ko) 2008-08-06 2019-02-18 베링거 인겔하임 인터내셔날 게엠베하 메트포르민 요법이 부적합한 환자에서의 당뇨병 치료
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