DK174337B1 - Fremgangsmåde til fremstilling af en peptidalkohol, peptidalkohol fremstillet ved fremgangsmåden samt udgangsmaterialer ved fremstillingen - Google Patents

Fremgangsmåde til fremstilling af en peptidalkohol, peptidalkohol fremstillet ved fremgangsmåden samt udgangsmaterialer ved fremstillingen Download PDF

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Publication number
DK174337B1
DK174337B1 DK198705327A DK532787A DK174337B1 DK 174337 B1 DK174337 B1 DK 174337B1 DK 198705327 A DK198705327 A DK 198705327A DK 532787 A DK532787 A DK 532787A DK 174337 B1 DK174337 B1 DK 174337B1
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Prior art keywords
group
resin
residue
peptide
acetalized
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DK198705327A
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Danish (da)
English (en)
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DK532787D0 (da
DK532787A (da
Inventor
Rainer Albert
Janos Pless
Walter Prikoszovich
Francois Cardinaux
Wilfried Bauer
Monika Mergler
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Novartis Ag
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Application filed by Novartis Ag filed Critical Novartis Ag
Publication of DK532787D0 publication Critical patent/DK532787D0/da
Publication of DK532787A publication Critical patent/DK532787A/da
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Publication of DK174337B1 publication Critical patent/DK174337B1/da

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/04—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length on carriers
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K9/00—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D319/00—Heterocyclic compounds containing six-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D319/04—1,3-Dioxanes; Hydrogenated 1,3-dioxanes
    • C07D319/06—1,3-Dioxanes; Hydrogenated 1,3-dioxanes not condensed with other rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/107—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides
    • C07K1/1072—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides by covalent attachment of residues or functional groups
    • C07K1/1077—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length by chemical modification of precursor peptides by covalent attachment of residues or functional groups by covalent attachment of residues other than amino acids or peptide residues, e.g. sugars, polyols, fatty acids
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Analytical Chemistry (AREA)
  • Diabetes (AREA)
  • Endocrinology (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Emergency Medicine (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
DK198705327A 1986-10-13 1987-10-12 Fremgangsmåde til fremstilling af en peptidalkohol, peptidalkohol fremstillet ved fremgangsmåden samt udgangsmaterialer ved fremstillingen DK174337B1 (da)

Applications Claiming Priority (10)

Application Number Priority Date Filing Date Title
DE3634825 1986-10-13
DE3634826 1986-10-13
DE3634826 1986-10-13
DE3634797 1986-10-13
DE3634797 1986-10-13
DE3634825 1986-10-13
DE3712626 1987-04-14
DE3712626 1987-04-14
CH315387 1987-08-17
CH315387 1987-08-17

Publications (3)

Publication Number Publication Date
DK532787D0 DK532787D0 (da) 1987-10-12
DK532787A DK532787A (da) 1988-04-14
DK174337B1 true DK174337B1 (da) 2002-12-16

Family

ID=27509117

Family Applications (1)

Application Number Title Priority Date Filing Date
DK198705327A DK174337B1 (da) 1986-10-13 1987-10-12 Fremgangsmåde til fremstilling af en peptidalkohol, peptidalkohol fremstillet ved fremgangsmåden samt udgangsmaterialer ved fremstillingen

Country Status (23)

Country Link
US (1) US5656721A (de)
JP (2) JPH0645639B2 (de)
KR (1) KR960016861B1 (de)
AU (2) AU617986B2 (de)
BE (1) BE1003752A4 (de)
CA (1) CA1340985C (de)
CH (2) CH682632A5 (de)
DE (1) DE3790635T1 (de)
DK (1) DK174337B1 (de)
ES (1) ES2007418A6 (de)
FI (1) FI874495A (de)
FR (1) FR2609991A1 (de)
GB (2) GB2199829B (de)
GR (1) GR871567B (de)
HU (3) HU206890B (de)
IE (1) IE912442A1 (de)
LU (1) LU87014A1 (de)
NL (1) NL194729C (de)
NZ (1) NZ222133A (de)
PL (1) PL157156B1 (de)
PT (1) PT85904B (de)
SE (2) SE8703938L (de)
WO (1) WO1988002756A2 (de)

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DE3910667A1 (de) * 1988-04-11 1989-10-19 Sandoz Ag Peptidderivate
GB8813339D0 (en) * 1988-06-06 1988-07-13 Sandoz Ltd Improvements in/relating to organic compounds
FR2638968B1 (fr) * 1988-11-11 1994-10-07 Sandoz Sa Nouvelle utilisation therapeutique de la somatostatine et de ses analogues et derives
US5753627A (en) * 1988-12-05 1998-05-19 Novartis Ag Use of certain complexed somatostatin peptides for the invivo imaging of somatostatin receptor-positive tumors and metastasis
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US5776894A (en) * 1988-12-05 1998-07-07 Novartis Ag Chelated somatostatin peptides and complexes thereof, pharmaceutical compositions containing them and their use in treating tumors
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US5632969A (en) * 1994-10-13 1997-05-27 Merck & Co., Inc. N3 S2 chelating ligands optionally radiolabelled with Tc or Re, useful for diagnostic or therapeutic applications
JP3896430B2 (ja) * 1996-07-15 2007-03-22 アークレイ株式会社 糖化アミノ化合物の製造方法
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WO2008121767A2 (en) 2007-03-28 2008-10-09 President And Fellows Of Harvard College Stitched polypeptides
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EP2310029B1 (de) 2008-06-12 2019-04-03 Ipsen Bioinnovation Limited Fusionsproteine zur Verwendung bei der Behandlung von Krebs
CN102112145B (zh) 2008-06-12 2014-07-30 辛它可辛有限公司 神经内分泌病的抑制
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FR2548673B1 (fr) * 1983-07-05 1985-10-04 Essilor Int Polymeres supports de produits actifs relargables et leur procede de preparation
LU85269A1 (fr) * 1984-03-26 1985-10-14 Techland S A Composes nouveaux de somatostatine,procede pour leur synthese,preparation a usage veterinaire contenant lesdits composes et procede pour le traitement d'animaux
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Also Published As

Publication number Publication date
WO1988002756A2 (en) 1988-04-21
NL194729B (nl) 2002-09-02
SE8703938L (sv) 1988-04-14
GB8800537D0 (en) 1988-02-10
HUT46710A (en) 1988-11-28
FR2609991B1 (de) 1995-03-10
NL194729C (nl) 2003-01-07
WO1988002756A3 (en) 1988-07-14
GB2199829B (en) 1991-04-17
HU906340D0 (en) 1991-04-29
JPS63101399A (ja) 1988-05-06
PL268173A1 (en) 1988-09-01
DK532787D0 (da) 1987-10-12
SE9301172D0 (sv) 1993-04-07
PT85904B (pt) 1990-08-31
JPH0645639B2 (ja) 1994-06-15
IE912442L (en) 1988-04-13
GB2199829A (en) 1988-07-20
CA1340985C (en) 2000-05-09
AU7956487A (en) 1988-04-14
AU634664B2 (en) 1993-02-25
FI874495A (fi) 1988-04-14
FI874495A0 (fi) 1987-10-12
IE912442A1 (en) 1992-02-12
BE1003752A4 (fr) 1992-06-09
US5656721A (en) 1997-08-12
DE3790635T1 (de) 1988-10-06
KR880005153A (ko) 1988-06-28
DK532787A (da) 1988-04-14
FR2609991A1 (fr) 1988-07-29
JPH0314599A (ja) 1991-01-23
NL8702345A (nl) 1988-05-02
HU206890B (en) 1993-01-28
GR871567B (en) 1988-02-16
KR960016861B1 (ko) 1996-12-23
NZ222133A (en) 1993-02-25
HU906341D0 (en) 1991-04-29
CH680512A5 (de) 1992-09-15
SE518630C2 (sv) 2002-11-05
SE9301172L (de) 1900-01-01
JP2744910B2 (ja) 1998-04-28
PT85904A (en) 1987-11-01
CH682632A5 (de) 1993-10-29
ES2007418A6 (es) 1989-06-16
GB2199831B (en) 1991-04-17
GB2199831A (en) 1988-07-20
PL157156B1 (pl) 1992-05-29
LU87014A1 (fr) 1988-05-03
SE8703938D0 (sv) 1987-10-12
AU617986B2 (en) 1991-12-12
AU8015091A (en) 1991-10-31
GB8723737D0 (en) 1987-11-11

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AHB Application shelved due to non-payment
B1 Patent granted (law 1993)
PUP Patent expired