US6955900B1
(en)
*
|
1993-02-02 |
2005-10-18 |
The Scripps Research Institute |
Methods for producing polypeptide binding sites, monoclonal antibodies and compositions thereof
|
US20060078561A1
(en)
*
|
1994-01-31 |
2006-04-13 |
The Trustees Of Boston University |
Polyclonal antibody libraries
|
DK1231268T3
(da)
|
1994-01-31 |
2005-11-21 |
Univ Boston |
Polyklonale antistofbiblioteker
|
PT859841E
(pt)
*
|
1995-08-18 |
2002-11-29 |
Morphosys Ag |
Bibliotecas de proteinas/ (poli) peptidos
|
US6017754A
(en)
*
|
1995-08-24 |
2000-01-25 |
Invitrogen Corporation |
System for isolating and identifying eukaryotic cells transfected with genes and vectors, host cells and methods thereof
|
FR2741892B1
(fr)
*
|
1995-12-04 |
1998-02-13 |
Pasteur Merieux Serums Vacc |
Procede de preparation d'une banque multicombinatoire de vecteurs d'expression de genes d'anticorps, banque et systemes d'expression d'anticorps "coliclonaux" obtenus
|
US6696251B1
(en)
*
|
1996-05-31 |
2004-02-24 |
Board Of Trustees Of The University Of Illinois |
Yeast cell surface display of proteins and uses thereof
|
GB9701425D0
(en)
|
1997-01-24 |
1997-03-12 |
Bioinvent Int Ab |
A method for in vitro molecular evolution of protein function
|
US6596850B1
(en)
*
|
1998-01-30 |
2003-07-22 |
Ixsys, Incorporated |
Anti-αv3β3 recombinant human antibodies, nucleic acids encoding same
|
US6590079B2
(en)
*
|
1997-01-30 |
2003-07-08 |
Ixsys, Incorporated |
Anti-αvβ3 recombinant human antibodies, nucleic acids encoding same
|
JP2002514919A
(ja)
*
|
1997-04-04 |
2002-05-21 |
バイオサイト ダイアグノスティックス,インコーポレイテッド |
多価ライブラリーおよびポリクローナルライブラリー
|
US6057098A
(en)
|
1997-04-04 |
2000-05-02 |
Biosite Diagnostics, Inc. |
Polyvalent display libraries
|
GB9722131D0
(en)
*
|
1997-10-20 |
1997-12-17 |
Medical Res Council |
Method
|
US6759243B2
(en)
*
|
1998-01-20 |
2004-07-06 |
Board Of Trustees Of The University Of Illinois |
High affinity TCR proteins and methods
|
BR9911882A
(pt)
|
1998-07-13 |
2005-02-15 |
Univ Texas |
Processo de tratamento de câncer empregando anticorpos a aminofosfolipìdios
|
CA2334170A1
(en)
|
1998-07-27 |
2000-02-10 |
Genentech, Inc. |
Improved transformation efficiency in phage display through modification of a coat protein
|
US6531580B1
(en)
*
|
1999-06-24 |
2003-03-11 |
Ixsys, Inc. |
Anti-αvβ3 recombinant human antibodies and nucleic acids encoding same
|
US7135287B1
(en)
|
1999-10-02 |
2006-11-14 |
Biosite, Inc. |
Human antibodies
|
US20070111259A1
(en)
*
|
1999-10-02 |
2007-05-17 |
Medarex, Inc. |
Human antibodies
|
US6794132B2
(en)
|
1999-10-02 |
2004-09-21 |
Biosite, Inc. |
Human antibodies
|
US6849425B1
(en)
|
1999-10-14 |
2005-02-01 |
Ixsys, Inc. |
Methods of optimizing antibody variable region binding affinity
|
US6680209B1
(en)
|
1999-12-06 |
2004-01-20 |
Biosite, Incorporated |
Human antibodies as diagnostic reagents
|
IL149809A0
(en)
*
|
1999-12-15 |
2002-11-10 |
Genentech Inc |
Shotgun scanning, a combinatorial method for mapping functional protein epitopes
|
US7229619B1
(en)
|
2000-11-28 |
2007-06-12 |
Medimmune, Inc. |
Methods of administering/dosing anti-RSV antibodies for prophylaxis and treatment
|
JP4992068B2
(ja)
|
2000-01-27 |
2012-08-08 |
メディミューン,エルエルシー |
超高親和性中和抗体
|
ES2390761T3
(es)
*
|
2000-03-01 |
2012-11-16 |
Medimmune, Llc |
Anticuerpos recombinantes de alta potencia y método para producción de los mismos
|
US6902734B2
(en)
|
2000-08-07 |
2005-06-07 |
Centocor, Inc. |
Anti-IL-12 antibodies and compositions thereof
|
UA81743C2
(uk)
|
2000-08-07 |
2008-02-11 |
Центокор, Инк. |
МОНОКЛОНАЛЬНЕ АНТИТІЛО ЛЮДИНИ, ЩО СПЕЦИФІЧНО ЗВ'ЯЗУЄТЬСЯ З ФАКТОРОМ НЕКРОЗУ ПУХЛИН АЛЬФА (ФНПα), ФАРМАЦЕВТИЧНА КОМПОЗИЦІЯ, ЩО ЙОГО МІСТИТЬ, ТА СПОСІБ ЛІКУВАННЯ РЕВМАТОЇДНОГО АРТРИТУ
|
US7288390B2
(en)
|
2000-08-07 |
2007-10-30 |
Centocor, Inc. |
Anti-dual integrin antibodies, compositions, methods and uses
|
US7198924B2
(en)
|
2000-12-11 |
2007-04-03 |
Invitrogen Corporation |
Methods and compositions for synthesis of nucleic acid molecules using multiple recognition sites
|
US6818216B2
(en)
*
|
2000-11-28 |
2004-11-16 |
Medimmune, Inc. |
Anti-RSV antibodies
|
US6855493B2
(en)
|
2000-11-28 |
2005-02-15 |
Medimmune, Inc. |
Methods of administering/dosing anti-RSV antibodies for prophylaxis and treatment
|
US7179900B2
(en)
*
|
2000-11-28 |
2007-02-20 |
Medimmune, Inc. |
Methods of administering/dosing anti-RSV antibodies for prophylaxis and treatment
|
US7087726B2
(en)
|
2001-02-22 |
2006-08-08 |
Genentech, Inc. |
Anti-interferon-α antibodies
|
EP1493028A4
(en)
*
|
2001-07-06 |
2006-06-14 |
Genentech Inc |
PHAGEN DISPLAY PRESENTED LIGANDS OF THE PDZ DOMAIN
|
US20030104604A1
(en)
*
|
2001-08-03 |
2003-06-05 |
Weiping Yang |
Genetically engineered bacterial strains for the display of foreign peptides on filamentous phage
|
EP1527341B1
(en)
|
2001-11-20 |
2009-06-17 |
Duke University |
Interfacial biomaterials
|
GB0202206D0
(en)
*
|
2002-01-31 |
2002-03-20 |
Bioinvent Int Ab |
Method of making libraries of anti-ligands
|
US7504364B2
(en)
*
|
2002-03-01 |
2009-03-17 |
Receptors Llc |
Methods of making arrays and artificial receptors
|
US7244592B2
(en)
|
2002-03-07 |
2007-07-17 |
Dyax Corp. |
Ligand screening and discovery
|
WO2003088911A2
(en)
*
|
2002-04-17 |
2003-10-30 |
Roberto Crea |
Universal libraries for immunoglobulins
|
US7405062B2
(en)
*
|
2002-05-14 |
2008-07-29 |
San Diego Antibody |
Method for cloning variable domain sequences of immunological gene repertoire
|
NZ556507A
(en)
*
|
2002-06-03 |
2010-03-26 |
Genentech Inc |
Synthetic antibody phage libraries
|
US7425618B2
(en)
*
|
2002-06-14 |
2008-09-16 |
Medimmune, Inc. |
Stabilized anti-respiratory syncytial virus (RSV) antibody formulations
|
US7132100B2
(en)
|
2002-06-14 |
2006-11-07 |
Medimmune, Inc. |
Stabilized liquid anti-RSV antibody formulations
|
KR101257584B1
(ko)
|
2002-07-15 |
2013-04-23 |
더 보드 오브 리전츠 오브 더 유니버시티 오브 텍사스 시스템 |
음이온성 인지질 및 아미노인지질에 결합하는 선택된 항체 및 치료하는데 있어서 이의 용도
|
JP4836451B2
(ja)
*
|
2002-07-18 |
2011-12-14 |
メルス ベー ヴェー |
抗体混合物の組換え生産
|
USRE47770E1
(en)
|
2002-07-18 |
2019-12-17 |
Merus N.V. |
Recombinant production of mixtures of antibodies
|
TW200501985A
(en)
*
|
2002-07-25 |
2005-01-16 |
Medimmune Inc |
Methods of treating and preventing RSV, hMPV, and PIV using anti-RSV, anti-hMPV, and anti-PIV antibodies
|
US20040067532A1
(en)
|
2002-08-12 |
2004-04-08 |
Genetastix Corporation |
High throughput generation and affinity maturation of humanized antibody
|
US20050170385A1
(en)
*
|
2002-09-16 |
2005-08-04 |
Receptors Llc |
Artificial receptors including gradients
|
US20050136483A1
(en)
*
|
2003-09-03 |
2005-06-23 |
Receptors Llc |
Nanodevices employing combinatorial artificial receptors
|
US20050037381A1
(en)
*
|
2002-09-16 |
2005-02-17 |
Receptors Llc |
Artificial receptors, building blocks, and methods
|
US7469076B2
(en)
*
|
2003-09-03 |
2008-12-23 |
Receptors Llc |
Sensors employing combinatorial artificial receptors
|
WO2005003326A2
(en)
*
|
2003-03-28 |
2005-01-13 |
Receptors Llc. |
Artificial receptors including reversibly immobilized building blocks and methods
|
US20040137481A1
(en)
*
|
2002-09-16 |
2004-07-15 |
Receptors Llc |
Artificial receptor building blocks, components, and kits
|
US20050037429A1
(en)
*
|
2003-03-28 |
2005-02-17 |
Receptors Llc |
Artificial receptors including reversibly immobilized building blocks and methods
|
US20050037428A1
(en)
*
|
2002-09-16 |
2005-02-17 |
Receptors Llc |
Artificial receptors including reversibly immobilized building blocks, the building blocks, and methods
|
US20060057625A1
(en)
*
|
2002-09-16 |
2006-03-16 |
Carlson Robert E |
Scaffold-based artificial receptors and methods
|
WO2004035537A2
(en)
|
2002-10-16 |
2004-04-29 |
Euro-Celtique S.A. |
Antibodies that bind cell-associated ca 125/o772p and methods of use thereof
|
WO2004041299A1
(en)
*
|
2002-11-05 |
2004-05-21 |
Institut Pasteur |
Dc-sign blockers and their use for preventing or treating viral infections.
|
US7427469B2
(en)
*
|
2002-11-05 |
2008-09-23 |
Institut Pasteur |
Method of treating cytomegalovirus with DC-SIGN blockers
|
EP1629090B1
(en)
*
|
2002-11-06 |
2014-03-05 |
iBio, Inc. |
Expression of foreign sequences in plants using trans-activation system
|
US7692063B2
(en)
*
|
2002-11-12 |
2010-04-06 |
Ibio, Inc. |
Production of foreign nucleic acids and polypeptides in sprout systems
|
US7491509B2
(en)
|
2003-02-03 |
2009-02-17 |
Fraunhofer Usa, Inc. |
System for expression of genes in plants
|
US7683238B2
(en)
*
|
2002-11-12 |
2010-03-23 |
iBio, Inc. and Fraunhofer USA, Inc. |
Production of pharmaceutically active proteins in sprouted seedlings
|
WO2004065416A2
(en)
*
|
2003-01-16 |
2004-08-05 |
Genentech, Inc. |
Synthetic antibody phage libraries
|
US20050008625A1
(en)
*
|
2003-02-13 |
2005-01-13 |
Kalobios, Inc. |
Antibody affinity engineering by serial epitope-guided complementarity replacement
|
BRPI0408315A
(pt)
|
2003-03-14 |
2006-03-07 |
Wyeth Corp |
anticorpo isolado, composição farmacêutica, ácido nucleico isolado, vetor de expressão, célula hospedeira, métodos de produzir um anticorpo, de gerar um anticorpo ou fragmento de ligação de antìgeno, de regular uma resposta imune, de tratar ou prevenir um distúrbio associado com célula imune em um paciente, de tratar ou prevenir um distúrbio hiperproliferativo em um paciente, e, kit de diagnóstico
|
ES2427641T3
(es)
|
2003-05-22 |
2013-10-31 |
Ibio, Inc. |
Molécula vehículo recombinante para la expresión, el suministro y la purificación de polipéptidos diana
|
US20100069614A1
(en)
|
2008-06-27 |
2010-03-18 |
Merus B.V. |
Antibody producing non-human mammals
|
US9708410B2
(en)
|
2003-05-30 |
2017-07-18 |
Janssen Biotech, Inc. |
Anti-tissue factor antibodies and compositions
|
CA2527694C
(en)
|
2003-05-30 |
2015-07-14 |
Hendricus Renerus Jacobus Mattheus Hoogenboom |
Fab library for the preparation of anti vegf and anti rabies virus fabs
|
WO2005004794A2
(en)
|
2003-06-09 |
2005-01-20 |
Alnylam Pharmaceuticals Inc. |
Method of treating neurodegenerative disease
|
US20070274997A1
(en)
*
|
2003-07-25 |
2007-11-29 |
Anthony Simmons |
Compositions and Methods for Herpes Simplex Prophylaxis and Treatment
|
EP1664115A2
(en)
*
|
2003-08-01 |
2006-06-07 |
Genentech, Inc. |
Antibody cdr polypeptide sequences with restricted diversity
|
US20070274988A1
(en)
*
|
2003-10-10 |
2007-11-29 |
Five Prime Therapeautics, Inc. |
Kiaa0779, Splice Variants Thereof, and Methods of Their Use
|
US7329725B1
(en)
*
|
2003-10-29 |
2008-02-12 |
Nastech Pharmaceutical Company Inc. |
Phage displayed Trp cage ligands
|
EP2287341B1
(en)
|
2003-12-01 |
2013-02-13 |
Life Technologies Corporation |
Nucleic acid molecules containing recombination sites and methods of using the same
|
ES2646560T3
(es)
|
2004-01-20 |
2017-12-14 |
Merus N.V. |
Mezclas de proteínas de unión
|
AU2005207003C1
(en)
|
2004-01-20 |
2013-06-13 |
Humanigen, Inc. |
Antibody specificity transfer using minimal essential binding determinants
|
ES2532609T3
(es)
*
|
2004-02-20 |
2015-03-30 |
Ibio, Inc. |
Sistemas y métodos para expresión clonales en plantas
|
US7785903B2
(en)
*
|
2004-04-09 |
2010-08-31 |
Genentech, Inc. |
Variable domain library and uses
|
AU2005250369A1
(en)
*
|
2004-05-18 |
2005-12-15 |
Genentech, Inc. |
M13 virus major coat protein variants for C-terminal and BI-terminal display of a heterologous protein
|
US20060051396A1
(en)
|
2004-06-16 |
2006-03-09 |
Affinergy, Inc. |
Biofunctional coatings
|
MX2007000103A
(es)
*
|
2004-07-06 |
2007-05-11 |
Bioren Inc |
Bibliotecas de anticuerpos universales.
|
EP1791975A4
(en)
*
|
2004-08-05 |
2007-11-07 |
Biosite Inc |
COMPOSITIONS AND METHODS FOR EXPRESSION AT THE SURFACE OF POLYPEPTIDE PHAGES
|
US7884052B2
(en)
*
|
2004-09-03 |
2011-02-08 |
Receptors Llc |
Combinatorial artificial receptors including tether building blocks on scaffolds
|
US7985715B2
(en)
*
|
2004-09-11 |
2011-07-26 |
Receptors Llc |
Combinatorial artificial receptors including peptide building blocks
|
CA2585891A1
(en)
*
|
2004-10-29 |
2006-05-11 |
Medimmune, Inc. |
Methods of preventing and treating rsv infections and related conditions
|
EP1870459B1
(en)
|
2005-03-31 |
2016-06-29 |
Chugai Seiyaku Kabushiki Kaisha |
Methods for producing polypeptides by regulating polypeptide association
|
ES2494921T3
(es)
*
|
2005-04-08 |
2014-09-16 |
Chugai Seiyaku Kabushiki Kaisha |
Anticuerpo que sustituye la función del factor VIII de coagulación sanguínea
|
SI1888113T1
(sl)
|
2005-05-27 |
2014-10-30 |
Biogen Idec Ma Inc. |
Protitelesa, ki veĹľejo TWEAK
|
WO2007117264A2
(en)
*
|
2005-08-03 |
2007-10-18 |
Fraunhofer Usa, Inc. |
Compositions and methods for production of immunoglobulins
|
IL172297A
(en)
|
2005-10-03 |
2016-03-31 |
Compugen Ltd |
Soluble vegfr-1 variants for the diagnosis of preeclampsia
|
US20070122408A1
(en)
*
|
2005-10-20 |
2007-05-31 |
The Scripps Research Institute |
Fc Labeling for Immunostaining and Immunotargeting
|
EP2465870A1
(en)
|
2005-11-07 |
2012-06-20 |
Genentech, Inc. |
Binding polypeptides with diversified and consensus VH/VL hypervariable sequences
|
ES2402576T3
(es)
*
|
2005-11-14 |
2013-05-06 |
Bioren, Inc. |
Ultrahumanización de anticuerpos por generación y selección de bibliotecas cohorte y blast de cdr maduras previstas
|
JP2009520949A
(ja)
|
2005-11-16 |
2009-05-28 |
アンブルックス,インコーポレイテッド |
非天然アミノ酸を含んでいる組成物および方法
|
EP1973951A2
(en)
*
|
2005-12-02 |
2008-10-01 |
Genentech, Inc. |
Binding polypeptides with restricted diversity sequences
|
JP5358187B2
(ja)
|
2005-12-15 |
2013-12-04 |
ジェネンテック, インコーポレイテッド |
ポリユビキチンを標的とする方法と組成物
|
RU2450020C2
(ru)
|
2006-01-05 |
2012-05-10 |
Дженентек, Инк. |
АНТИТЕЛА ПРОТИВ EphB4 И СПОСОБЫ ИХ ПРИМЕНЕНИЯ
|
WO2007080597A2
(en)
|
2006-01-16 |
2007-07-19 |
Compugen Ltd. |
Polynucleotide and polypeptide sequences and methods for diagnosis
|
US20070186296A1
(en)
*
|
2006-02-02 |
2007-08-09 |
Wyeth |
Cloning, characterization, and application of tnfrsf19 in neurological disorders
|
JP2009526526A
(ja)
*
|
2006-02-13 |
2009-07-23 |
フラウンホーファー ユーエスエー, インコーポレイテッド |
インフルエンザ抗原、ワクチン組成物、および関連する方法
|
CA2642056A1
(en)
*
|
2006-02-13 |
2007-08-23 |
Fraunhofer Usa, Inc. |
Hpv antigens, vaccine compositions, and related methods
|
US8277816B2
(en)
*
|
2006-02-13 |
2012-10-02 |
Fraunhofer Usa, Inc. |
Bacillus anthracis antigens, vaccine compositions, and related methods
|
AR059851A1
(es)
|
2006-03-16 |
2008-04-30 |
Genentech Inc |
Anticuerpos de la egfl7 y metodos de uso
|
WO2007109243A2
(en)
*
|
2006-03-20 |
2007-09-27 |
Duramed Pharmaceuticals, Inc. |
Methods for comparing the immunogenicity of products and uses thereof
|
EP3056568B1
(en)
|
2006-03-31 |
2021-09-15 |
Chugai Seiyaku Kabushiki Kaisha |
Methods for controlling blood pharmacokinetics of antibodies
|
DK2009101T3
(da)
|
2006-03-31 |
2018-01-15 |
Chugai Pharmaceutical Co Ltd |
Antistofmodifikationsfremgangsmåde til oprensning af et bispecifikt antistof
|
US20070292936A1
(en)
*
|
2006-05-09 |
2007-12-20 |
Genentech, Inc. |
Binding polypeptides with optimized scaffolds
|
US8148085B2
(en)
|
2006-05-15 |
2012-04-03 |
Sea Lane Biotechnologies, Llc |
Donor specific antibody libraries
|
AU2007249160B2
(en)
*
|
2006-05-15 |
2013-09-12 |
I2 Pharmaceuticals, Inc. |
Neutralizing antibodies to influenza viruses
|
RS54163B1
(en)
|
2006-05-30 |
2015-12-31 |
Genentech Inc. |
ANTI-CD22 ANTIBODIES, THEIR IMMUNCONJUGATES AND THEIR USE
|
JP2009539384A
(ja)
|
2006-06-06 |
2009-11-19 |
ジェネンテック・インコーポレーテッド |
抗dll4抗体および抗dll4抗体使用の方法
|
US20100003189A1
(en)
|
2006-07-14 |
2010-01-07 |
The Regents Of The University Of California |
Cancer biomarkers and methods of use thereof
|
US20090252745A1
(en)
*
|
2006-09-15 |
2009-10-08 |
Duke University |
Amino acids in the HCV core polypeptide domain 3 and correlation with steatosis
|
WO2008042754A2
(en)
|
2006-10-02 |
2008-04-10 |
Sea Lane Biotechnologies, Llc |
Design and construction of diverse synthetic peptide and polypeptide libraries
|
LT2845866T
(lt)
|
2006-10-27 |
2017-07-10 |
Genentech, Inc. |
Antikūnai ir imunokonjugatai bei jų panaudojimas
|
CA2674788A1
(en)
|
2007-01-08 |
2008-07-17 |
Government Of The Usa, As Represented By The Secretary, Department Of He Alth And Human Services |
Slco1b3 genotype
|
US9896511B2
(en)
|
2007-01-10 |
2018-02-20 |
The United States Of America, As Represented By The Secretary, Dept. Of Health And Human Services |
Antibodies that bind to TL1A and methods of treating inflammatory or autoimmune disease comprising administering such antibodies
|
US7960139B2
(en)
|
2007-03-23 |
2011-06-14 |
Academia Sinica |
Alkynyl sugar analogs for the labeling and visualization of glycoconjugates in cells
|
CA2685558A1
(en)
*
|
2007-04-28 |
2008-11-06 |
Fraunhofer Usa, Inc. |
Trypanosoma antigens, vaccine compositions, and related methods
|
EP1997830A1
(en)
|
2007-06-01 |
2008-12-03 |
AIMM Therapeutics B.V. |
RSV specific binding molecules and means for producing them
|
EP2178558B1
(en)
|
2007-07-11 |
2014-04-30 |
iBio, Inc. |
Yersinia pestis antigens, vaccine compositions, and related methods
|
MY150531A
(en)
|
2007-07-16 |
2014-01-30 |
Genentech Inc |
Anti-cd79b antibodies and immunoconjugates and methods of use
|
PE20140625A1
(es)
|
2007-07-16 |
2014-05-29 |
Genentech Inc |
ANTICUERPOS ANTI-CD79b E INMUNOCONJUGADOS HUMANIZADOS
|
WO2009026397A2
(en)
*
|
2007-08-20 |
2009-02-26 |
Fraunhofer Usa, Inc. |
Prophylactic and therapeutic influenza vaccines, antigens, compositions, and methods
|
WO2009026496A1
(en)
*
|
2007-08-22 |
2009-02-26 |
University Of Southern California |
Grp78 and tumor angiogenesis
|
US8877688B2
(en)
|
2007-09-14 |
2014-11-04 |
Adimab, Llc |
Rationally designed, synthetic antibody libraries and uses therefor
|
EP3124497B1
(en)
|
2007-09-14 |
2020-04-15 |
Adimab, LLC |
Rationally designed, synthetic antibody libraries and uses therefor
|
CN106519025B
(zh)
|
2007-09-26 |
2021-04-23 |
中外制药株式会社 |
利用cdr的氨基酸取代来改变抗体等电点的方法
|
JP5620106B2
(ja)
|
2007-10-24 |
2014-11-05 |
株式会社糖鎖工学研究所 |
増強されたエフェクター機能を有するポリペプチド
|
US8034905B2
(en)
|
2007-11-09 |
2011-10-11 |
Affitech Research, AS |
Anti-VEGF antibody compositions and methods
|
TWI580694B
(zh)
|
2007-11-30 |
2017-05-01 |
建南德克公司 |
抗-vegf抗體
|
JP5523345B2
(ja)
|
2008-01-18 |
2014-06-18 |
ジェネンテック, インコーポレイテッド |
K63結合型ポリユビキチンを標的とする方法と組成物
|
PE20091318A1
(es)
|
2008-01-31 |
2009-09-16 |
Genentech Inc |
Anticuerpos anti-cd79b e inmunoconjugados y metodos de uso de los mismos
|
CA2721052C
(en)
|
2008-04-11 |
2023-02-21 |
Chugai Seiyaku Kabushiki Kaisha |
Antigen-binding molecule capable of binding to two or more antigen molecules repeatedly
|
US7833530B2
(en)
*
|
2008-05-15 |
2010-11-16 |
Selexys Pharmaceuticals Corporation |
Methods of inhibiting the PSGL-1-mediated adhesion and chemokine-mediated migration with PSGL-1-specific antibodies
|
US20090291073A1
(en)
*
|
2008-05-20 |
2009-11-26 |
Ward Keith W |
Compositions Comprising PKC-theta and Methods for Treating or Controlling Ophthalmic Disorders Using Same
|
JP2009278908A
(ja)
*
|
2008-05-22 |
2009-12-03 |
Fujifilm Corp |
抗オステオカルシン抗体及びそれを用いた免疫測定方法
|
WO2009155484A2
(en)
|
2008-06-20 |
2009-12-23 |
Wyeth |
Compositions and methods of use of orf1358 from beta-hemolytic streptococcal strains
|
JP5986745B2
(ja)
|
2008-07-15 |
2016-09-06 |
アカデミア シニカAcademia Sinica |
Ptfe様のアルミニウム・コート・ガラススライド上のグリカンアレイおよび関連する方法
|
JP6049163B2
(ja)
*
|
2008-07-21 |
2016-12-21 |
イミューノメディクス、インコーポレイテッドImmunomedics, Inc. |
改善された治療上の特徴のための抗体の構造変異体
|
KR20160116056A
(ko)
|
2008-08-14 |
2016-10-06 |
테바 파마슈티컬즈 오스트레일리아 피티와이 엘티디 |
항-il-12/il-23 항체
|
AU2008360658B2
(en)
|
2008-08-15 |
2015-02-19 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
S0X9, prostaglandin D2 and retinoic acid for treating pigmentary conditions and melanoma
|
US20100081575A1
(en)
*
|
2008-09-22 |
2010-04-01 |
Robert Anthony Williamson |
Methods for creating diversity in libraries and libraries, display vectors and methods, and displayed molecules
|
WO2010033229A2
(en)
|
2008-09-22 |
2010-03-25 |
Calmune Corporation |
Methods and vectors for display of molecules and displayed molecules and collections
|
WO2010037046A1
(en)
|
2008-09-28 |
2010-04-01 |
Fraunhofer Usa, Inc. |
Humanized neuraminidase antibody and methods of use thereof
|
EP3025727A1
(en)
|
2008-10-02 |
2016-06-01 |
The J. David Gladstone Institutes |
Methods of treating liver disease
|
CA2744555A1
(en)
|
2008-11-26 |
2010-06-03 |
Five Prime Therapeutics, Inc. |
Compositions and methods for regulating collagen and smooth muscle actin expression by serpine2
|
WO2010061393A1
(en)
|
2008-11-30 |
2010-06-03 |
Compugen Ltd. |
He4 variant nucleotide and amino acid sequences, and methods of use thereof
|
CN101768213B
(zh)
|
2008-12-30 |
2012-05-30 |
中国科学院遗传与发育生物学研究所 |
一种与植物分蘖数目相关的蛋白及其编码基因与应用
|
CN101817879A
(zh)
|
2009-02-26 |
2010-09-01 |
中国科学院遗传与发育生物学研究所 |
金属硫蛋白及其编码基因与应用
|
BRPI1006448B1
(pt)
|
2009-03-25 |
2021-08-17 |
Genentech, Inc |
Anticorpo antagonista anti-fgfr3, anticorpo monoclonal, polinucleotídeo, vetor, microorganismo transgênico, método para produção de um anticorpo anti-fgfr3, formulação farmacêutica e usos do anticorpo antagonista anti-fgfr3
|
PE20120878A1
(es)
|
2009-04-01 |
2012-08-06 |
Genentech Inc |
ANTICUERPOS ANTI-FcRH5 E INMUNOCONJUGADOS
|
US20110033389A1
(en)
*
|
2009-04-29 |
2011-02-10 |
Zhifeng Chen |
Modified antibodies for passive immunotherapy
|
AU2010249470B2
(en)
*
|
2009-05-20 |
2015-06-25 |
Novimmune S.A. |
Synthetic Polypeptide Libraries And Methods For Generating Naturally Diversified Polypeptide Variants
|
EP2435568B1
(en)
|
2009-05-29 |
2014-07-02 |
MorphoSys AG |
Collection of synthetic antibodies for treating disease
|
TW201106972A
(en)
|
2009-07-27 |
2011-03-01 |
Genentech Inc |
Combination treatments
|
CN102656189B
(zh)
|
2009-08-13 |
2014-10-08 |
克鲁塞尔荷兰公司 |
针对人呼吸道合胞病毒(rsv)的抗体以及使用方法
|
US9321823B2
(en)
|
2009-09-02 |
2016-04-26 |
Genentech, Inc. |
Mutant smoothened and methods of using the same
|
US20110189183A1
(en)
|
2009-09-18 |
2011-08-04 |
Robert Anthony Williamson |
Antibodies against candida, collections thereof and methods of use
|
WO2011041391A1
(en)
|
2009-09-29 |
2011-04-07 |
Fraunhofer Usa, Inc. |
Influenza hemagglutinin antibodies, compositions, and related methods
|
US8568726B2
(en)
|
2009-10-06 |
2013-10-29 |
Medimmune Limited |
RSV specific binding molecule
|
NZ599337A
(en)
|
2009-10-22 |
2013-05-31 |
Genentech Inc |
Anti-hepsin antibodies and methods using same
|
WO2011056497A1
(en)
|
2009-10-26 |
2011-05-12 |
Genentech, Inc. |
Activin receptor type iib compositions and methods of use
|
WO2011056502A1
(en)
|
2009-10-26 |
2011-05-12 |
Genentech, Inc. |
Bone morphogenetic protein receptor type ii compositions and methods of use
|
WO2011056494A1
(en)
|
2009-10-26 |
2011-05-12 |
Genentech, Inc. |
Activin receptor-like kinase-1 antagonist and vegfr3 antagonist combinations
|
AU2010315101B2
(en)
|
2009-11-04 |
2016-01-28 |
Fabrus Llc |
Methods for affinity maturation-based antibody optimization
|
ES2636971T3
(es)
|
2009-11-05 |
2017-10-10 |
F. Hoffmann-La Roche Ag |
Procedimientos y composición para la secreción de polipéptidos heterógenos
|
US10087236B2
(en)
|
2009-12-02 |
2018-10-02 |
Academia Sinica |
Methods for modifying human antibodies by glycan engineering
|
US11377485B2
(en)
|
2009-12-02 |
2022-07-05 |
Academia Sinica |
Methods for modifying human antibodies by glycan engineering
|
JP5818805B2
(ja)
|
2009-12-11 |
2015-11-18 |
ジェネンテック, インコーポレイテッド |
抗vegf−c抗体及びその使用方法
|
BR112012013093A2
(pt)
|
2009-12-21 |
2017-12-12 |
Genentech Inc |
''formulação farmacêutica aquosa estável, artigo, métodos para estabilizar um anticorpo, para tratamento de uma doença ou distúrbio em um indivíduo, para reduzir a agregação de um anticorpo monoclonal terapêutico e de fabricação de uma formulação farmaceutica, frasco e tanque de aço inoxidável
|
JP5852010B2
(ja)
|
2009-12-23 |
2016-02-03 |
ジェネンテック, インコーポレイテッド |
抗Bv8抗体およびその使用
|
WO2011092989A1
(ja)
|
2010-01-29 |
2011-08-04 |
東レ株式会社 |
ポリ乳酸系樹脂シート
|
US20130045492A1
(en)
|
2010-02-08 |
2013-02-21 |
Regeneron Pharmaceuticals, Inc. |
Methods For Making Fully Human Bispecific Antibodies Using A Common Light Chain
|
US9796788B2
(en)
|
2010-02-08 |
2017-10-24 |
Regeneron Pharmaceuticals, Inc. |
Mice expressing a limited immunoglobulin light chain repertoire
|
ES2547142T5
(es)
*
|
2010-02-08 |
2021-12-09 |
Regeneron Pharma |
Cadena ligera común de ratón
|
WO2011130332A1
(en)
|
2010-04-12 |
2011-10-20 |
Academia Sinica |
Glycan arrays for high throughput screening of viruses
|
EP2564200B8
(en)
|
2010-04-27 |
2019-10-02 |
The Regents of The University of California |
Cancer biomarkers and methods of use thereof
|
JP5947289B2
(ja)
|
2010-05-10 |
2016-07-06 |
アカデミア シニカAcademia Sinica |
抗インフルエンザ活性を有するザナミビルホスホネート同族体およびインフルエンザウイルスのオセルタミビルに対する感受性の決定
|
BR112012029866A2
(pt)
|
2010-06-03 |
2017-03-07 |
Genentech Inc |
método para a determinação da presença de uma proteína steap-1
|
AU2011274472B2
(en)
|
2010-07-09 |
2017-03-30 |
Janssen Vaccines & Prevention B.V. |
Anti-human respiratory syncytial virus (RSV) antibodies and methods of use
|
WO2012019061A2
(en)
|
2010-08-05 |
2012-02-09 |
Stem Centrx, Inc. |
Novel effectors and methods of use
|
SG10201506782XA
(en)
|
2010-08-27 |
2015-10-29 |
Stem Centrx Inc |
Notum protein modulators and methods of use
|
JP6327855B2
(ja)
|
2010-09-03 |
2018-05-23 |
アッヴィ・ステムセントルクス・エル・エル・シー |
新規モジュレータ及びその使用法
|
JP6121904B2
(ja)
|
2010-09-08 |
2017-04-26 |
ハロザイム インコーポレイテッド |
条件的活性治療用タンパク質を評価および同定する、または発展させる方法
|
ES2588981T3
(es)
|
2010-10-05 |
2016-11-08 |
Genentech, Inc. |
Smoothened mutante y métodos de uso de la misma
|
EP2632489B1
(en)
|
2010-10-27 |
2020-01-15 |
The Research Foundation for The State University of New York |
Compositions targeting the soluble extracellular domain of e-cadherin and related methods for cancer therapy
|
SI2644698T1
(en)
|
2010-11-17 |
2018-05-31 |
Chugai Seiyaku Kabushiki Kaisha |
MULTISPECIFIC ANTIGEN-TUBULAR MOLECULAR, WITH AN ALTERNATIVE FUNCTION TO THE FACTOR OF BLOOD VIOLATION VIII
|
DK2640742T3
(da)
|
2010-11-19 |
2018-12-03 |
Morphosys Ag |
Samling af antistofsekvenser og disses anvendelser
|
RU2016123839A
(ru)
|
2010-12-08 |
2018-11-30 |
АббВай Стемсентркс ЭлЭлСи |
Новые модуляторы и способы их применения
|
WO2012092539A2
(en)
|
2010-12-31 |
2012-07-05 |
Takeda Pharmaceutical Company Limited |
Antibodies to dll4 and uses thereof
|
SA112330278B1
(ar)
|
2011-02-18 |
2015-10-09 |
ستيم سينتركس، انك. |
مواد ضابطة جديدة وطرق للاستخدام
|
AU2012245073B2
(en)
|
2011-04-21 |
2016-02-11 |
Garvan Institute Of Medical Research |
Modified variable domain molecules and methods for producing and using them b
|
JP2014518883A
(ja)
|
2011-05-20 |
2014-08-07 |
ガバメント・オブ・ザ・ユナイテッド・ステイツ,アズ・リプリゼンテッド・バイ・ザ・セクレタリー,デパートメント・オブ・ヘルス・アンド・ヒューマン・サーヴィシズ |
T細胞媒介疾病の病態を改善させるためのtl1a−dr3相互作用の遮断及びその抗体
|
IL297371A
(en)
|
2011-08-05 |
2022-12-01 |
Regeneron Pharma |
Humanized mice possess a universal light chain
|
US20130058947A1
(en)
|
2011-09-02 |
2013-03-07 |
Stem Centrx, Inc |
Novel Modulators and Methods of Use
|
US10100080B2
(en)
|
2011-09-28 |
2018-10-16 |
Era Biotech, S.A. |
Split inteins and uses thereof
|
WO2013046960A1
(ja)
*
|
2011-09-29 |
2013-04-04 |
Necソフト株式会社 |
ペプチド抗体のスクリーニングに使用する核酸構築物およびそれを用いたスクリーニング方法
|
US20150050269A1
(en)
|
2011-09-30 |
2015-02-19 |
Chugai Seiyaku Kabushiki Kaisha |
Antigen-binding molecule promoting disappearance of antigens having plurality of biological activities
|
KR102398736B1
(ko)
|
2011-10-31 |
2022-05-16 |
추가이 세이야쿠 가부시키가이샤 |
중쇄와 경쇄의 회합이 제어된 항원 결합 분자
|
CN104411717A
(zh)
|
2012-01-09 |
2015-03-11 |
斯克利普斯研究所 |
具有超长cdr3s的人源化抗体
|
JP6684490B2
(ja)
|
2012-01-09 |
2020-04-22 |
ザ・スクリップス・リサーチ・インスティテュート |
超長相補性決定領域及びその使用
|
SI2817338T1
(sl)
|
2012-02-24 |
2017-11-30 |
Abbvie Stemcentrx Llc |
Modulatorji DLL3 in postopki uporabe
|
AU2013229786B2
(en)
|
2012-03-08 |
2017-06-22 |
Halozyme, Inc. |
Conditionally active anti-epidermal growth factor receptor antibodies and methods of use thereof
|
US20140013456A1
(en)
|
2012-03-16 |
2014-01-09 |
Regeneron Pharmaceuticals, Inc. |
Histidine Engineered Light Chain Antibodies and Genetically Modified Non-Human Animals for Generating the Same
|
KR20140134672A
(ko)
|
2012-03-16 |
2014-11-24 |
리제너론 파마슈티칼스 인코포레이티드 |
pH-의존성 결합 특성을 나타내는 항원-결합 단백질을 생성하는 마우스
|
US20140087362A1
(en)
|
2012-03-16 |
2014-03-27 |
Aladar A. Szalay |
Methods for assessing effectiveness and monitoring oncolytic virus treatment
|
HUE037659T2
(hu)
|
2012-03-16 |
2018-09-28 |
Regeneron Pharma |
Hisztidinmódosított könnyûlánc antitestek és genetikailag módosított rágcsálók ennek az elõállítására
|
NZ629077A
(en)
|
2012-03-16 |
2015-12-24 |
Regeneron Pharma |
Non-human animals expressing ph-sensitive immunoglobulin sequences
|
US10130714B2
(en)
|
2012-04-14 |
2018-11-20 |
Academia Sinica |
Enhanced anti-influenza agents conjugated with anti-inflammatory activity
|
JP6272299B2
(ja)
|
2012-04-20 |
2018-01-31 |
メルス ナムローゼ フェンノートシャップ |
Ig様分子を生産する方法、Ig様分子の混合物、組み換え宿主細胞、医薬組成物、宿主細胞を作成する方法、および培養物
|
PT2692865E
(pt)
*
|
2012-07-30 |
2015-02-06 |
Nbe Therapeutics Llc |
Identificação mediada por transposição de proteínas funcionais ou de ligação específicas
|
AU2013306098A1
(en)
|
2012-08-18 |
2015-02-12 |
Academia Sinica |
Cell-permeable probes for identification and imaging of sialidases
|
EP2888238A4
(en)
|
2012-08-21 |
2016-01-27 |
Academia Sinica |
BENZOCYCLO-OCTYNE COMPOUNDS AND USES THEREOF
|
SI2928923T1
(sl)
|
2012-12-10 |
2020-03-31 |
Biogen Ma Inc. |
Protitelesa proti antigenu 2 dendritičnih celic v krvi in njihova uporaba
|
US10717965B2
(en)
|
2013-01-10 |
2020-07-21 |
Gloriana Therapeutics, Inc. |
Mammalian cell culture-produced neublastin antibodies
|
MX2015010682A
(es)
|
2013-02-22 |
2016-05-31 |
Stemcentrx Inc |
Nuevos conjugados de anticuerpos y usos de los mismos.
|
AU2014243700B2
(en)
|
2013-03-13 |
2019-01-24 |
Genentech, Inc. |
Formulations with reduced oxidation
|
RS60534B1
(sr)
|
2013-03-13 |
2020-08-31 |
Hoffmann La Roche |
Formulacije sa smanjenom oksidacijom
|
NZ711567A
(en)
|
2013-03-13 |
2020-04-24 |
Genentech Inc |
Antibody formulations
|
AR095399A1
(es)
|
2013-03-13 |
2015-10-14 |
Genentech Inc |
Formulaciones con oxidación reducida, método
|
AR095398A1
(es)
|
2013-03-13 |
2015-10-14 |
Genentech Inc |
Formulaciones con oxidación reducida
|
JP2016515120A
(ja)
|
2013-03-15 |
2016-05-26 |
バイオジェン・エムエイ・インコーポレイテッドBiogen MA Inc. |
抗アルファvベータ5抗体を用いた急性腎損傷の治療及び予防
|
WO2014145091A1
(en)
|
2013-03-15 |
2014-09-18 |
Genentech, Inc. |
Cell culture media and methods of antibody production
|
ES2798307T3
(es)
|
2013-03-15 |
2020-12-10 |
Hoffmann La Roche |
Composiciones de cultivo de células con antioxidantes y procedimientos para la producción de polipéptidos
|
US10086054B2
(en)
|
2013-06-26 |
2018-10-02 |
Academia Sinica |
RM2 antigens and use thereof
|
EP3013347B1
(en)
|
2013-06-27 |
2019-12-11 |
Academia Sinica |
Glycan conjugates and use thereof
|
WO2015017146A2
(en)
|
2013-07-18 |
2015-02-05 |
Fabrus, Inc. |
Antibodies with ultralong complementarity determining regions
|
US10640574B2
(en)
|
2013-07-18 |
2020-05-05 |
Taurus Biosciences, Llc |
Humanized antibodies with ultralong complementary determining regions
|
DK3036320T4
(da)
|
2013-08-19 |
2024-05-06 |
Biogen Ma Inc |
Styring af proteinglycosylering ved hjælp af dyrkningsmedietilsætning og cellekulturprocesparametre
|
CA2922529A1
(en)
|
2013-08-28 |
2015-03-05 |
Stemcentrx, Inc. |
Novel sez6 modulators and methods of use
|
BR112016004242A8
(pt)
|
2013-08-28 |
2018-06-12 |
Stemcentrx Inc |
Métodos para conjugação sítio-específica de anticorpos e composições
|
CN105682666B
(zh)
|
2013-09-06 |
2021-06-01 |
中央研究院 |
使用醣脂激活人类iNKT细胞
|
CA2922562A1
(en)
|
2013-09-12 |
2015-03-19 |
Halozyme, Inc. |
Modified anti-epidermal growth factor receptor antibodies and methods of use thereof
|
HUE057005T2
(hu)
|
2013-09-25 |
2022-04-28 |
Bioverativ Therapeutics Inc |
Oszlopon történõ vírusinaktiváló eljárások
|
JP6942465B2
(ja)
|
2013-09-27 |
2021-09-29 |
ジェネンテック, インコーポレイテッド |
抗pdl1抗体製剤
|
MX2016003616A
(es)
|
2013-09-27 |
2016-07-21 |
Chugai Pharmaceutical Co Ltd |
Metodo para producir heteromultimeros de polipeptidos.
|
CN105940115B
(zh)
|
2013-11-15 |
2021-07-06 |
巴斯德研究所 |
恶性疟原虫青蒿素耐药性的分子标记物
|
JP2017500017A
(ja)
|
2013-12-20 |
2017-01-05 |
バイオジェン・エムエイ・インコーポレイテッドBiogen MA Inc. |
生物薬剤フェドバッチ生産能力及び生産物品質を改善するための灌流シード培養の使用
|
EP2960252A1
(en)
|
2014-06-26 |
2015-12-30 |
Institut Pasteur |
Phospholipase for treatment of immunosuppression
|
PL3712174T3
(pl)
|
2013-12-24 |
2022-07-04 |
Janssen Pharmaceutica Nv |
Przeciwciała i fragmenty anty-vista
|
US10238700B2
(en)
|
2014-01-02 |
2019-03-26 |
Genelux Corporation |
Oncolytic virus adjunct therapy with agents that increase virus infectivity
|
US10150818B2
(en)
|
2014-01-16 |
2018-12-11 |
Academia Sinica |
Compositions and methods for treatment and detection of cancers
|
WO2016114819A1
(en)
|
2015-01-16 |
2016-07-21 |
Academia Sinica |
Compositions and methods for treatment and detection of cancers
|
TW201620939A
(zh)
|
2014-01-16 |
2016-06-16 |
中央研究院 |
治療及檢測癌症之組合物及方法
|
CA2937539A1
(en)
|
2014-02-04 |
2015-08-13 |
Genentech, Inc. |
Mutant smoothened and methods of using the same
|
KR20170008202A
(ko)
|
2014-02-21 |
2017-01-23 |
애브비 스템센트알엑스 엘엘씨 |
흑색종에 사용하기 위한 항-dll3 항체 및 약물 접합체
|
JP6636498B2
(ja)
|
2014-03-21 |
2020-01-29 |
リジェネロン・ファーマシューティカルズ・インコーポレイテッドRegeneron Pharmaceuticals, Inc. |
単一ドメイン結合タンパク質を作る非ヒト動物
|
EP3122869B2
(en)
|
2014-03-24 |
2022-08-10 |
Biogen MA Inc. |
Methods for overcoming glutamine deprivation during mammalian cell culture
|
TWI797430B
(zh)
|
2014-03-27 |
2023-04-01 |
中央研究院 |
反應性標記化合物及其用途
|
EP4050026A1
(en)
|
2014-04-01 |
2022-08-31 |
Adimab, LLC |
Method of obtaining or identifying one or more common light chains for use in preparing a multispecific antibody
|
IL248511B
(en)
|
2014-05-13 |
2022-07-01 |
Bavarian Nordic As |
Combined therapy for the treatment of cancer with a focovirus expressing the antigen and a monoclonal antibody against tim-3
|
CA2950423A1
(en)
|
2014-05-27 |
2015-12-03 |
Academia Sinica |
Compositions and methods relating to universal glycoforms for enhanced antibody efficacy
|
KR20170003720A
(ko)
|
2014-05-27 |
2017-01-09 |
아카데미아 시니카 |
항-cd20 글리코항체 및 이의 용도
|
US10118969B2
(en)
|
2014-05-27 |
2018-11-06 |
Academia Sinica |
Compositions and methods relating to universal glycoforms for enhanced antibody efficacy
|
AU2015267045B2
(en)
|
2014-05-27 |
2021-02-25 |
Academia Sinica |
Anti-HER2 glycoantibodies and uses thereof
|
EP3154582A4
(en)
|
2014-05-28 |
2018-01-10 |
Academia Sinica |
Anti-tnf-alpha glycoantibodies and uses thereof
|
TWI695011B
(zh)
|
2014-06-18 |
2020-06-01 |
美商梅爾莎納醫療公司 |
抗her2表位之單株抗體及其使用之方法
|
ES2727137T3
(es)
|
2014-08-28 |
2019-10-14 |
Halozyme Inc |
Terapia combinada con una enzima de degradación de hialuronano y un inhibidor de puntos de control inmunitario
|
WO2016040369A2
(en)
|
2014-09-08 |
2016-03-17 |
Academia Sinica |
HUMAN iNKT CELL ACTIVATION USING GLYCOLIPIDS
|
US20160137727A1
(en)
|
2014-09-15 |
2016-05-19 |
Genentech, Inc. |
Antibody formulations
|
MA40764A
(fr)
|
2014-09-26 |
2017-08-01 |
Chugai Pharmaceutical Co Ltd |
Agent thérapeutique induisant une cytotoxicité
|
TWI701435B
(zh)
|
2014-09-26 |
2020-08-11 |
日商中外製藥股份有限公司 |
測定fviii的反應性之方法
|
TWI700300B
(zh)
|
2014-09-26 |
2020-08-01 |
日商中外製藥股份有限公司 |
中和具有第viii凝血因子(fviii)機能替代活性的物質之抗體
|
MA41685A
(fr)
|
2014-10-17 |
2017-08-22 |
Biogen Ma Inc |
Supplémentation en cuivre pour la régulation de la glycosylation dans un procédé de culture cellulaire de mammifère
|
MA40864A
(fr)
|
2014-10-31 |
2017-09-05 |
Biogen Ma Inc |
Hypotaurine, gaba, bêta-alanine et choline pour la régulation de l'accumulation de sous-produits résiduaires dans des procédés de culture de cellules mammifères
|
RU2017119185A
(ru)
|
2014-11-05 |
2018-12-05 |
Дженентек, Инк. |
Антитела против fgfr2/3 и способы их применения
|
US11033637B2
(en)
|
2014-11-21 |
2021-06-15 |
University Of Maryland, Baltimore |
Targeted structure-specific particulate delivery systems
|
EP3227687A4
(en)
|
2014-12-05 |
2018-10-24 |
Prelude, Inc. |
Dcis recurrence and invasive breast cancer
|
US10495645B2
(en)
|
2015-01-16 |
2019-12-03 |
Academia Sinica |
Cancer markers and methods of use thereof
|
US9975965B2
(en)
|
2015-01-16 |
2018-05-22 |
Academia Sinica |
Compositions and methods for treatment and detection of cancers
|
EP3789766A1
(en)
|
2015-01-24 |
2021-03-10 |
Academia Sinica |
Novel glycan conjugates and methods of use thereof
|
KR102630294B1
(ko)
|
2015-01-24 |
2024-01-26 |
아카데미아 시니카 |
암 마커 및 이를 사용하는 방법
|
EP3250590B1
(en)
|
2015-01-30 |
2021-09-15 |
Academia Sinica |
Compositions and methods relating to universal glycoforms for enhanced anti-ssea4 antibody efficacy
|
EP3253793A4
(en)
|
2015-02-02 |
2018-11-14 |
i2 Pharmaceuticals, Inc. |
Anti-surrogate light chain antibodies
|
US10330683B2
(en)
|
2015-02-04 |
2019-06-25 |
Genentech, Inc. |
Mutant smoothened and methods of using the same
|
WO2016149678A1
(en)
|
2015-03-19 |
2016-09-22 |
Regeneron Pharmaceuticals, Inc. |
Non-human animals that select for light chain variable regions that bind antigen
|
US11142587B2
(en)
|
2015-04-01 |
2021-10-12 |
Chugai Seiyaku Kabushiki Kaisha |
Method for producing polypeptide hetero-oligomer
|
EP3280444B1
(en)
|
2015-04-10 |
2024-05-08 |
Adimab, LLC |
Methods for purifying heterodimeric multispecific antibodies from parental homodimeric antibody species
|
EP3285811A1
(en)
|
2015-04-21 |
2018-02-28 |
Institut Gustave Roussy |
Therapeutic methods, products and compositions inhibiting znf555
|
EP3313882B1
(en)
|
2015-06-24 |
2020-03-11 |
Janssen Pharmaceutica NV |
Anti-vista antibodies and fragments
|
TW202330904A
(zh)
|
2015-08-04 |
2023-08-01 |
美商再生元醫藥公司 |
補充牛磺酸之細胞培養基及用法
|
WO2017041027A1
(en)
|
2015-09-04 |
2017-03-09 |
Obi Pharma, Inc. |
Glycan arrays and method of use
|
WO2017115773A1
(ja)
|
2015-12-28 |
2017-07-06 |
中外製薬株式会社 |
Fc領域含有ポリペプチドの精製を効率化するための方法
|
CA3007491A1
(en)
|
2015-12-30 |
2017-07-06 |
Genentech, Inc. |
Use of tryptophan derivatives for protein formulations
|
AU2016380988B2
(en)
|
2015-12-30 |
2022-07-21 |
Genentech, Inc. |
Formulations with reduced degradation of polysorbate
|
CN109071625A
(zh)
|
2016-02-04 |
2018-12-21 |
柯瑞斯公司 |
平滑化突变体和其使用方法
|
TWI756204B
(zh)
|
2016-02-12 |
2022-03-01 |
比利時商楊森製藥公司 |
抗vista抗體及片段、其用途及鑑定其之方法
|
JP2019515876A
(ja)
|
2016-03-08 |
2019-06-13 |
アカデミア シニカAcademia Sinica |
N−グリカンおよびそのアレイのモジュール合成のための方法
|
BR112018068461A2
(pt)
|
2016-03-15 |
2019-01-22 |
Mersana Therapeutics Inc |
conjugado, composição farmacêutica, métodos para preparação de um conjugado e para alívio de um sintoma de um câncer.
|
WO2017161206A1
(en)
|
2016-03-16 |
2017-09-21 |
Halozyme, Inc. |
Conjugates containing conditionally active antibodies or antigen-binding fragments thereof, and methods of use
|
US11034992B2
(en)
|
2016-03-23 |
2021-06-15 |
The General Hospital Corporation |
Assays and methods for detecting UDP-glucose
|
WO2017172990A1
(en)
|
2016-03-29 |
2017-10-05 |
Obi Pharma, Inc. |
Antibodies, pharmaceutical compositions and methods
|
CA3019164A1
(en)
|
2016-03-29 |
2017-10-05 |
Janssen Biotech, Inc. |
Method of treating psoriasis with increased interval dosing of anti-il12/23 antibody
|
US10980894B2
(en)
|
2016-03-29 |
2021-04-20 |
Obi Pharma, Inc. |
Antibodies, pharmaceutical compositions and methods
|
DK3440208T3
(da)
*
|
2016-04-06 |
2020-12-07 |
Zumutor Biologics Inc |
Vektorer til kloning og ekspression af proteiner, metoder og anvendelser heraf
|
WO2017175058A1
(en)
|
2016-04-07 |
2017-10-12 |
Janssen Pharmaceutica Nv |
Anti-vista antibodies and fragments, uses thereof, and methods of identifying same
|
AU2017252128A1
(en)
|
2016-04-22 |
2018-11-01 |
Obi Pharma, Inc. |
Cancer immunotherapy by immune activation or immune modulation via Globo series antigens
|
EP3487880A1
(en)
|
2016-07-25 |
2019-05-29 |
Biogen MA Inc. |
Anti-hspa5 (grp78) antibodies and uses thereof
|
CA3032049C
(en)
|
2016-07-27 |
2023-11-07 |
Obi Pharma, Inc. |
Immunogenic/therapeutic glycan compositions and uses thereof
|
TWI786054B
(zh)
|
2016-07-29 |
2022-12-11 |
台灣浩鼎生技股份有限公司 |
人類抗體、醫藥組合物、及其方法
|
CN109963868B
(zh)
|
2016-08-22 |
2023-11-14 |
醣基生医股份有限公司 |
抗体、结合片段及使用方法
|
RU2766233C2
(ru)
|
2016-09-06 |
2022-02-10 |
Чугаи Сейяку Кабусики Кайся |
Способы применения биспецифического антитела, которое распознает фактор свертывания ix и/или активированный фактор свертывания ix и фактор свертывания x и/или активированный фактор свертывания x
|
US20180094052A1
(en)
|
2016-09-30 |
2018-04-05 |
Janssen Biotech, Inc. |
Safe and Effective Method of Treating Psoriasis with Anti-IL23 Specific Antibody
|
WO2018093841A1
(en)
|
2016-11-16 |
2018-05-24 |
Janssen Biotech, Inc. |
Method of treating psoriasis with anti-il-23 specific antibody
|
EP3541414A4
(en)
|
2016-11-21 |
2020-11-11 |
OBI Pharma, Inc. |
CONJUGATE BIOLOGICAL MOLECULES, PHARMACEUTICAL COMPOSITIONS AND PROCESSES
|
JP2020506916A
(ja)
|
2017-01-30 |
2020-03-05 |
ヤンセン バイオテツク,インコーポレーテツド |
活動性乾癬性関節炎の治療のための抗tnf抗体、組成物、及び方法
|
CA3052578A1
(en)
|
2017-02-07 |
2018-08-16 |
Janssen Biotech, Inc. |
Anti-tnf antibodies, compositions, and methods for the treatment of active ankylosing spondylitis
|
WO2019055618A1
(en)
|
2017-09-15 |
2019-03-21 |
Arizona Board Of Regents On Behalf Of Arizona State University |
METHODS OF CLASSIFYING RESPONSES TO ANTICANCER IMMUNOTHERAPY
|
TW201922780A
(zh)
|
2017-09-25 |
2019-06-16 |
美商健生生物科技公司 |
以抗il12/il23抗體治療狼瘡之安全且有效之方法
|
MA50667A
(fr)
|
2017-09-29 |
2020-08-05 |
Chugai Pharmaceutical Co Ltd |
Molécule multispécifique de liaison à l'antigène ayant une activité de substitution de la fonction de cofacteur du facteur viii de coagulation sanguine (fviii), et formulation pharmaceutique contenant ladite molécule en tant que principe actif
|
WO2019150309A1
(en)
|
2018-02-02 |
2019-08-08 |
Hammack Scott |
Modulators of gpr68 and uses thereof for treating and preventing diseases
|
EP3530282A1
(en)
|
2018-02-27 |
2019-08-28 |
Diaccurate |
Therapeutic methods
|
KR20200129125A
(ko)
|
2018-03-05 |
2020-11-17 |
얀센 바이오테크 인코포레이티드 |
항-il23 특이적 항체로 크론병을 치료하는 방법
|
JP7333332B2
(ja)
*
|
2018-03-14 |
2023-08-24 |
エフ. ホフマン-ラ ロシュ アーゲー |
抗体のアフィニティ成熟のための方法
|
TW202035444A
(zh)
|
2018-06-27 |
2020-10-01 |
台灣浩鼎生技股份有限公司 |
用於糖蛋白工程的糖苷合成酶變體及其使用方法
|
WO2020016838A2
(en)
|
2018-07-18 |
2020-01-23 |
Janssen Biotech, Inc. |
Sustained response predictors after treatment with anti-il23 specific antibody
|
WO2020033485A1
(en)
|
2018-08-08 |
2020-02-13 |
Genentech, Inc. |
Use of tryptophan derivatives and l-methionine for protein formulation
|
AU2019339508A1
(en)
|
2018-09-14 |
2021-04-15 |
Prelude Corporation |
Method of selection for treatment of subjects at risk of invasive breast cancer
|
KR20210064315A
(ko)
|
2018-09-24 |
2021-06-02 |
얀센 바이오테크 인코포레이티드 |
항-il12/il23 항체로 궤양성 결장염을 치료하는 안전하고 효과적인 방법
|
WO2020070303A1
(en)
|
2018-10-05 |
2020-04-09 |
Bavarian Nordic A/S |
Combination therapy for treating cancer with an intravenous administration of a recombinant mva and an immune checkpoint antagonist or agonist
|
WO2020086408A1
(en)
|
2018-10-26 |
2020-04-30 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
A high-yield perfusion-based transient gene expression bioprocess
|
EP3883599A1
(en)
|
2018-11-20 |
2021-09-29 |
Bavarian Nordic A/S |
Therapy for treating cancer with an intratumoral and/or intravenous administration of a recombinant mva encoding 4-1bbl (cd137l) and/or cd40l
|
WO2020104943A2
(en)
|
2018-11-20 |
2020-05-28 |
Janssen Biotech, Inc. |
Safe and effective method of treating psoriasis with anti-il-23 specific antibody
|
EP3897722A4
(en)
|
2018-12-18 |
2022-09-14 |
Janssen Biotech, Inc. |
SAFE AND EFFECTIVE METHOD OF TREATING LUPUS WITH AN ANTI-IL12/IL23 ANTIBODY
|
CA3126654A1
(en)
|
2019-01-15 |
2020-07-23 |
Janssen Biotech, Inc. |
Anti-tnf antibody compositions and methods for the treatment of juvenile idiopathic arthritis
|
CA3127748A1
(en)
|
2019-01-23 |
2020-07-30 |
Janssen Biotech, Inc. |
Anti-tnf antibody compositions for use in methods for the treatment of psoriatic arthritis
|
EP3693063A1
(en)
|
2019-02-06 |
2020-08-12 |
Diaccurate |
Methods and compositions for treating cancer
|
EA202192508A1
(ru)
|
2019-03-14 |
2022-03-29 |
Янссен Байотек, Инк. |
Способы получения композиций антитела к фно
|
CN113825765A
(zh)
|
2019-03-14 |
2021-12-21 |
詹森生物科技公司 |
用于制备抗il12/il23抗体组合物的制造方法
|
MA55283A
(fr)
|
2019-03-14 |
2022-01-19 |
Janssen Biotech Inc |
Procédés de production de compositions d'anticorps anti-tnf
|
JP2022525179A
(ja)
|
2019-03-14 |
2022-05-11 |
ヤンセン バイオテツク,インコーポレーテツド |
抗tnf抗体組成物を産生するための産生方法
|
MA55383A
(fr)
|
2019-03-18 |
2022-01-26 |
Janssen Biotech Inc |
Méthode de traitement du psoriasis chez des sujets pédiatriques avec un anticorps anti-il12/il23
|
KR20220004087A
(ko)
|
2019-04-19 |
2022-01-11 |
추가이 세이야쿠 가부시키가이샤 |
항체 개변 부위 인식 키메라 수용체
|
JP2022534020A
(ja)
|
2019-05-23 |
2022-07-27 |
ヤンセン バイオテツク,インコーポレーテツド |
Il-23及びtnfアルファに対する抗体の併用療法による炎症性腸疾患の治療方法
|
CN114173873A
(zh)
|
2019-06-03 |
2022-03-11 |
詹森生物科技公司 |
用于治疗活动性强直性脊柱炎的抗tnf抗体、组合物和方法
|
MA56015A
(fr)
|
2019-06-03 |
2022-04-06 |
Janssen Biotech Inc |
Compositions d'anticorps anti-tnf et méthodes pour le traitement de l'arthrite psoriasique
|
EP3998083A4
(en)
|
2019-07-12 |
2023-08-23 |
Chugai Seiyaku Kabushiki Kaisha |
ANTI-MUTATION TYPE FGFR3 ANTIBODY AND USE THEREOF
|
WO2021028752A1
(en)
|
2019-08-15 |
2021-02-18 |
Janssen Biotech, Inc. |
Anti-tfn antibodies for treating type i diabetes
|
WO2021067550A1
(en)
|
2019-10-02 |
2021-04-08 |
Arizona Board Of Regents On Behalf Of Arizona State University |
Methods and compositions for identifying neoantigens for use in treating and preventing cancer
|
CN114867491A
(zh)
|
2019-11-20 |
2022-08-05 |
巴法里安诺迪克有限公司 |
用于肿瘤内和/或静脉内施用以治疗癌症的重组mva病毒
|
WO2021239666A1
(en)
|
2020-05-26 |
2021-12-02 |
Diaccurate |
Therapeutic methods
|
AU2022232007A1
(en)
|
2021-03-12 |
2023-10-26 |
Janssen Biotech, Inc. |
Method of treating psoriatic arthritis patients with inadequate response to tnf therapy with anti-il23 specific antibody
|
CN117751138A
(zh)
|
2021-03-12 |
2024-03-22 |
詹森生物科技公司 |
用抗il23特异性抗体治疗银屑病关节炎的安全且有效的方法
|
KR20240032991A
(ko)
|
2021-07-09 |
2024-03-12 |
얀센 바이오테크 인코포레이티드 |
항-tnf 항체 조성물의 생성을 위한 제조 방법
|
IL309987A
(en)
|
2021-07-09 |
2024-03-01 |
Janssen Biotech Inc |
Production methods for the production of anti-IL12/IL23 antibody compositions
|
US20230040065A1
(en)
|
2021-07-09 |
2023-02-09 |
Janssen Biotech, Inc. |
Manufacturing Methods for Producing Anti-TNF Antibody Compositions
|
WO2023073615A1
(en)
|
2021-10-29 |
2023-05-04 |
Janssen Biotech, Inc. |
Methods of treating crohn's disease with anti-il23 specific antibody
|
WO2023084488A1
(en)
|
2021-11-15 |
2023-05-19 |
Janssen Biotech, Inc. |
Methods of treating crohn's disease with anti-il23 specific antibody
|
US20230159633A1
(en)
|
2021-11-23 |
2023-05-25 |
Janssen Biotech, Inc. |
Method of Treating Ulcerative Colitis with Anti-IL23 Specific Antibody
|
WO2023118508A1
(en)
|
2021-12-23 |
2023-06-29 |
Bavarian Nordic A/S |
Recombinant mva viruses for intraperitoneal administration for treating cancer
|
WO2023187707A1
(en)
|
2022-03-30 |
2023-10-05 |
Janssen Biotech, Inc. |
Method of treating mild to moderate psoriasis with il-23 specific antibody
|
WO2023223265A1
(en)
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2023-11-23 |
Janssen Biotech, Inc. |
Method for evaluating and treating psoriatic arthritis with il23 antibody
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