DK0627406T3 - 2-Amino-1,3-propandiolforbindelser og immunundertrykkende midler - Google Patents
2-Amino-1,3-propandiolforbindelser og immunundertrykkende midlerInfo
- Publication number
- DK0627406T3 DK0627406T3 DK93923035T DK93923035T DK0627406T3 DK 0627406 T3 DK0627406 T3 DK 0627406T3 DK 93923035 T DK93923035 T DK 93923035T DK 93923035 T DK93923035 T DK 93923035T DK 0627406 T3 DK0627406 T3 DK 0627406T3
- Authority
- DK
- Denmark
- Prior art keywords
- optionally substituted
- amino
- same
- immunosuppressants
- propanediol
- Prior art date
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- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
- C07D207/32—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
- C07D207/325—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms with substituted hydrocarbon radicals directly attached to the ring nitrogen atom
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
- A61K31/235—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids having an aromatic ring attached to a carboxyl group
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- C07C215/06—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being saturated and acyclic
- C07C215/10—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being saturated and acyclic with one amino group and at least two hydroxy groups bound to the carbon skeleton
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- C07C215/04—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being saturated
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- C07C215/34—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being unsaturated and containing six-membered aromatic rings containing hydroxy groups and carbon atoms of six-membered aromatic rings bound to the same carbon atom of the carbon skeleton and at least one hydroxy group bound to another carbon atom of the carbon skeleton
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- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
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- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Compounds Containing Sulfur Atoms (AREA)
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Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
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JP28328192 | 1992-10-21 | ||
JP17942793 | 1993-07-20 | ||
PCT/JP1993/001515 WO1994008943A1 (fr) | 1992-10-21 | 1993-10-18 | Compose 2-amino-1,3-propanediol et immunosuppresseur |
Publications (1)
Publication Number | Publication Date |
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DK0627406T3 true DK0627406T3 (da) | 1999-07-12 |
Family
ID=26499282
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK93923035T DK0627406T3 (da) | 1992-10-21 | 1993-10-18 | 2-Amino-1,3-propandiolforbindelser og immunundertrykkende midler |
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US (3) | US5604229A (fr) |
EP (1) | EP0627406B1 (fr) |
JP (1) | JP2579602B2 (fr) |
KR (1) | KR0155015B1 (fr) |
AT (1) | ATE172711T1 (fr) |
CA (1) | CA2126337C (fr) |
CY (2) | CY2215B1 (fr) |
DE (2) | DE69321823T2 (fr) |
DK (1) | DK0627406T3 (fr) |
ES (1) | ES2126658T3 (fr) |
HK (1) | HK1013281A1 (fr) |
LU (1) | LU91832I2 (fr) |
WO (1) | WO1994008943A1 (fr) |
Families Citing this family (162)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ES2171191T3 (es) * | 1994-08-22 | 2002-09-01 | Mitsubishi Pharma Corp | Compuesto de benceno y uso medicinal del mismo. |
US5948820A (en) | 1994-08-22 | 1999-09-07 | Yoshitomi Pharmaceutical Industries, Ltd. | Benzene compound and pharmaceutical use thereof |
EP0812588B1 (fr) * | 1995-12-28 | 2004-10-13 | Mitsubishi Pharma Corporation | Composition pharmaceutique destineé à l'administration topique comprenant de la 2-amino-2-(2-(4-octylphényl)ethyl)propane-1,3-diol pour le traitement des maladies causées par un trouble immunitaire |
JP2002241272A (ja) * | 1996-07-18 | 2002-08-28 | Mitsubishi Pharma Corp | 医薬処方組成物 |
US6476004B1 (en) | 1996-07-18 | 2002-11-05 | Mitsubishi Pharma Corporation | Pharmaceutical composition |
JPH11209277A (ja) * | 1998-01-19 | 1999-08-03 | Yoshitomi Pharmaceut Ind Ltd | 医薬組成物 |
GB9624038D0 (en) | 1996-11-19 | 1997-01-08 | Sandoz Ltd | Organic compounds |
DK0990440T3 (da) * | 1997-02-27 | 2009-02-23 | Novartis Ag | Farmaceutisk sammensætning indeholdende 2-amino-2[2-(4-octylphenyl)-ethyl]-propan-1,3-diol, en lecithin og et saccharid |
PT1002792E (pt) | 1997-04-04 | 2004-12-31 | Mitsubishi Pharma Corp | Compostos de 2-aminopropano-1,3-diol, sua utilizacao medicinal e intermediariosda sintese dos mesmos |
WO1999001420A1 (fr) * | 1997-07-03 | 1999-01-14 | Taito Co., Ltd. | Procede de preparation de derives d'acide 2-aminomalonique, et intermediaires utilises dans ce procede |
JPH1180026A (ja) | 1997-09-02 | 1999-03-23 | Yoshitomi Pharmaceut Ind Ltd | 新規免疫抑制剤、その使用方法およびその同定方法 |
ATE288414T1 (de) | 1998-11-11 | 2005-02-15 | Novartis Pharma Gmbh | Herstellung von 2-amino-2(2-(4- alkylphenyl)äthyl)propan-1,3-diolen |
CN1144779C (zh) * | 1999-03-11 | 2004-04-07 | 杭州中美华东制药有限公司 | 制备2-[2-(4-烷基苯基)-乙基]-2-氨基-丙二醇的方法以及其中制得的中间产物 |
JP4627356B2 (ja) * | 1999-06-30 | 2011-02-09 | 松森 昭 | ウイルス性心筋炎の予防または治療薬剤 |
EP1207882A4 (fr) * | 1999-07-30 | 2003-03-19 | Vertex Pharma | Derives d'amines acycliques et cycliques |
CN100415735C (zh) * | 2000-07-13 | 2008-09-03 | 三共株式会社 | 氨基醇衍生物 |
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JPS6050186B2 (ja) * | 1980-07-15 | 1985-11-07 | 三井東圧化学株式会社 | 2−メルカプトエチルアミンハロゲン化水素酸塩類の製造法 |
JPS6050783B2 (ja) * | 1981-03-20 | 1985-11-11 | 三井東圧化学株式会社 | S,s′−ビス(2−アミノエチル)ジチオカ−ボネ−トジハイドロハライド誘導体の製造方法 |
JPS58101108A (ja) * | 1981-12-11 | 1983-06-16 | Unitika Ltd | キレ−ト形成基を有するフエノ−ル樹脂とその製造方法及び吸着処理方法 |
DE3420308C2 (de) * | 1983-05-31 | 1998-06-18 | Toyo Boseki | Polyurethanzusammensetzung mit verbesserten Färbeeigenschaften |
US4910218A (en) * | 1985-11-22 | 1990-03-20 | Burroughs Wellcome Co. | Phenanthro[2,3-6]thiophene derivatives, pharmaceutical compositions and use |
JPS632904A (ja) * | 1986-06-20 | 1988-01-07 | Ss Pharmaceut Co Ltd | 植物生長調節剤 |
JPS6343140A (ja) * | 1986-08-08 | 1988-02-24 | Fuji Photo Film Co Ltd | ハロゲン化銀カラ−写真感光材料の処理方法 |
EP0410176A1 (fr) * | 1989-07-07 | 1991-01-30 | Yoshitomi Pharmaceutical Industries, Ltd. | Composés dérivés de l'acide amino-2 pentanoique et leur application comme immunosuppresseurs |
EP0450527A3 (fr) * | 1990-03-30 | 1991-10-30 | Kao Corporation | Amides N-tris (hydroxyméthyl)méthyl d'acides gras et compositions cosmétiques les contenant |
JPH049309A (ja) * | 1990-04-25 | 1992-01-14 | Kao Corp | 化粧料 |
JPH0469320A (ja) * | 1990-07-06 | 1992-03-04 | Kao Corp | 毛髪化粧料 |
JP2868887B2 (ja) * | 1990-11-06 | 1999-03-10 | 花王株式会社 | 薬用化粧料 |
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JPH06509559A (ja) * | 1991-03-19 | 1994-10-27 | セラピューティック パッチ リサーチ エヌ.ブイ. | 膜透過エンハンサーとしてのアミノアルコール誘導体組成物及び方法 |
JPH0578294A (ja) * | 1991-09-19 | 1993-03-30 | Kao Corp | 分岐脂肪酸アミド並びにその製造方法及び製造中間体 |
-
1993
- 1993-10-18 DK DK93923035T patent/DK0627406T3/da active
- 1993-10-18 ES ES93923035T patent/ES2126658T3/es not_active Expired - Lifetime
- 1993-10-18 EP EP93923035A patent/EP0627406B1/fr not_active Expired - Lifetime
- 1993-10-18 AT AT93923035T patent/ATE172711T1/de active
- 1993-10-18 US US08/244,942 patent/US5604229A/en not_active Expired - Lifetime
- 1993-10-18 DE DE69321823T patent/DE69321823T2/de not_active Expired - Lifetime
- 1993-10-18 CA CA002126337A patent/CA2126337C/fr not_active Expired - Lifetime
- 1993-10-18 KR KR1019940702174A patent/KR0155015B1/ko not_active IP Right Cessation
- 1993-10-18 JP JP6509845A patent/JP2579602B2/ja not_active Expired - Lifetime
- 1993-10-18 WO PCT/JP1993/001515 patent/WO1994008943A1/fr active IP Right Grant
- 1993-10-18 DE DE201112100012 patent/DE122011100012I1/de active Pending
-
1996
- 1996-10-02 US US08/725,890 patent/US5719176A/en not_active Expired - Lifetime
-
1997
- 1997-08-14 US US08/911,602 patent/US5952316A/en not_active Expired - Lifetime
-
1998
- 1998-12-22 HK HK98114539A patent/HK1013281A1/xx not_active IP Right Cessation
-
2000
- 2000-04-27 CY CY0000010A patent/CY2215B1/xx unknown
-
2011
- 2011-06-30 CY CY2011006C patent/CY2011006I1/el unknown
- 2011-06-30 LU LU91832C patent/LU91832I2/fr unknown
Also Published As
Publication number | Publication date |
---|---|
CA2126337C (fr) | 2003-06-24 |
US5719176A (en) | 1998-02-17 |
ATE172711T1 (de) | 1998-11-15 |
US5604229A (en) | 1997-02-18 |
EP0627406A4 (fr) | 1995-04-12 |
DE69321823D1 (de) | 1998-12-03 |
HK1013281A1 (en) | 1999-08-20 |
US5952316A (en) | 1999-09-14 |
CA2126337A1 (fr) | 1994-04-28 |
DE69321823T2 (de) | 1999-06-02 |
KR0155015B1 (ko) | 1998-12-01 |
EP0627406B1 (fr) | 1998-10-28 |
WO1994008943A1 (fr) | 1994-04-28 |
CY2011006I2 (el) | 2016-12-14 |
DE122011100012I1 (de) | 2011-10-20 |
LU91832I2 (fr) | 2011-08-30 |
JP2579602B2 (ja) | 1997-02-05 |
ES2126658T3 (es) | 1999-04-01 |
EP0627406A1 (fr) | 1994-12-07 |
KR940703803A (ko) | 1994-12-12 |
CY2215B1 (en) | 2003-04-18 |
CY2011006I1 (el) | 2016-12-14 |
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