PE20100371A1 - Agonistas del receptor s1p para el tratamiento de malaria cerebral - Google Patents
Agonistas del receptor s1p para el tratamiento de malaria cerebralInfo
- Publication number
- PE20100371A1 PE20100371A1 PE2009001210A PE2009001210A PE20100371A1 PE 20100371 A1 PE20100371 A1 PE 20100371A1 PE 2009001210 A PE2009001210 A PE 2009001210A PE 2009001210 A PE2009001210 A PE 2009001210A PE 20100371 A1 PE20100371 A1 PE 20100371A1
- Authority
- PE
- Peru
- Prior art keywords
- treatment
- cerebral malaria
- receptor agonists
- formulation
- receptor
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0014—Skin, i.e. galenical aspects of topical compositions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
- A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
- A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
- A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
- A61K9/7046—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds
- A61K9/7053—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds obtained by reactions only involving carbon to carbon unsaturated bonds, e.g. polyvinyl, polyisobutylene, polystyrene
- A61K9/7061—Polyacrylates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
- A61P33/06—Antimalarials
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P39/00—General protective or antinoxious agents
- A61P39/06—Free radical scavengers or antioxidants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Epidemiology (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Dermatology (AREA)
- Mycology (AREA)
- Pain & Pain Management (AREA)
- Microbiology (AREA)
- Immunology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Rheumatology (AREA)
- Urology & Nephrology (AREA)
- Neurosurgery (AREA)
- Toxicology (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Biochemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicinal Preparation (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Abstract
SE REFIERE A UNA FORMULACION FARMACEUTICA QUE CONTIENE: A) UN AGONISTA DEL RECEPTOR DE LA ESFINGOSINA-1-FOSFATO (S1P) DE FORMULA (I) DONDE Rp ES FENILO SUSTITUIDO CON ALQUILO(C6-C18), CICLOALQUILO, HETEROARILO O HETEROCICLO, EN DONDE UN COMPUESTO PREFERIDO ES FTY720; Y B) UNA AGENTE ACTIVO ADICIONAL TALES COMO i) UN FARMACO ANTIMALARIA TAL COMO QUININA, QUINIDINA, ENTRE OTROS, ii) UN DIURETICO OSMOTICO TAL COMO MANITOL, UREA, ENTRE OTROS, iii) UN ANTICONVULSIVANTE TAL COMO DIAZEPAN, FENITOINA, FENOBARBITAL, ENTRE OTROS, iv) UN ANTIPIRETICO TAL COMO PARACETAMOL, v) UN ANTIOXIDANTE, O vi) UN ANTIINFLAMATORIO. DICHA FORMULACION SE PRESENTA COMO UNA FORMA DE DOSIFICACION PARA SU ADMINISTRACION TOPICA, TRANSDERMICA O INTRAVENOSA SIENDO UTIL EN EL TRATAMIENTO DE LA MALARIA CEREBRAL
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US10999108P | 2008-10-31 | 2008-10-31 | |
US22997009P | 2009-07-30 | 2009-07-30 |
Publications (1)
Publication Number | Publication Date |
---|---|
PE20100371A1 true PE20100371A1 (es) | 2010-06-01 |
Family
ID=41621568
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PE2009001210A PE20100371A1 (es) | 2008-10-31 | 2009-10-28 | Agonistas del receptor s1p para el tratamiento de malaria cerebral |
Country Status (12)
Country | Link |
---|---|
US (1) | US20100112037A1 (es) |
EP (1) | EP2349334A1 (es) |
JP (1) | JP2012507546A (es) |
CN (1) | CN102196820A (es) |
AR (1) | AR074062A1 (es) |
AU (1) | AU2009308843A1 (es) |
CA (1) | CA2741546A1 (es) |
CL (1) | CL2009002017A1 (es) |
PE (1) | PE20100371A1 (es) |
TW (1) | TW201021790A (es) |
UY (1) | UY32214A (es) |
WO (1) | WO2010051349A1 (es) |
Families Citing this family (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2011159864A1 (en) * | 2010-06-17 | 2011-12-22 | Bracco Imaging S.P.A. | Jte013 analogs and methods of making and using same |
CN103328492A (zh) * | 2010-11-22 | 2013-09-25 | 阿勒根公司 | 作为受体调节剂具有疗效的新型化合物 |
WO2015053878A1 (en) * | 2013-10-11 | 2015-04-16 | Teikoku Pharma Usa, Inc. | Topical sphingosine-1-phosphate receptor agonist formulations and methods of using the same |
WO2015147335A1 (ja) * | 2014-03-27 | 2015-10-01 | 国立大学法人大阪大学 | 脳マラリアの診断および治療 |
US11541018B2 (en) | 2016-06-23 | 2023-01-03 | Corium, Llc | Adhesive matrix with hydrophilic and hydrophobic domains and a therapeutic agent |
JP7251033B2 (ja) | 2016-07-27 | 2023-04-04 | コリウム, エルエルシー | ドネペジル経皮送達システム |
CN109789113A (zh) | 2016-07-27 | 2019-05-21 | 考里安国际公司 | 美金刚透皮递送系统 |
EP3490559A1 (en) * | 2016-07-27 | 2019-06-05 | Corium International, Inc. | Transdermal delivery systems with pharmacokinetics bioequivalent to oral delivery |
AU2018392686A1 (en) | 2017-12-20 | 2020-07-09 | Corium Pharma Solutions, Inc. | Transdermal adhesive composition comprising a volatile liquid therapeutic agent having low melting point |
EP3810274A4 (en) * | 2018-06-21 | 2022-03-16 | Sanovel Ilac Sanayi Ve Ticaret Anonim Sirketi | COMBINATION OF FINGOLIMOD AND AT LEAST ONE ANTI-PILEPTIC |
Family Cites Families (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DK0627406T3 (da) * | 1992-10-21 | 1999-07-12 | Taito Co | 2-Amino-1,3-propandiolforbindelser og immunundertrykkende midler |
WO2005025553A2 (en) * | 2003-09-12 | 2005-03-24 | Neuronova Ab | Treatment of disorders of nervous systemsystem with fty720 |
GB0411929D0 (en) * | 2004-05-27 | 2004-06-30 | Novartis Ag | Organic compounds |
US7649098B2 (en) * | 2006-02-24 | 2010-01-19 | Lexicon Pharmaceuticals, Inc. | Imidazole-based compounds, compositions comprising them and methods of their use |
MY146775A (en) * | 2006-08-08 | 2012-09-28 | Kyorin Seiyaku Kk | Amino alcohol derivative and immunosuppressive agent having same as an active ingredient |
RU2009128062A (ru) * | 2006-12-21 | 2011-01-27 | Эбботт Лэборетриз (Us) | Соединения агонисты и антагонисты рецептора сфингозин-1-фосфата |
WO2008124210A1 (en) * | 2007-02-14 | 2008-10-16 | Emory University | Methods and compositions for treating or preventing infection using leukocyte sequestration agents |
AR065980A1 (es) * | 2007-04-12 | 2009-07-15 | Lexicon Pharmaceuticals Inc | Metodos para preparar compuestos basados en imidazol |
TW200920355A (en) * | 2007-09-06 | 2009-05-16 | Lexicon Pharmaceuticals Inc | Compositions and methods for treating immunological and inflammatory diseases and disorders |
-
2009
- 2009-10-28 AR ARP090104143A patent/AR074062A1/es unknown
- 2009-10-28 PE PE2009001210A patent/PE20100371A1/es not_active Application Discontinuation
- 2009-10-29 JP JP2011534744A patent/JP2012507546A/ja active Pending
- 2009-10-29 AU AU2009308843A patent/AU2009308843A1/en not_active Abandoned
- 2009-10-29 US US12/608,332 patent/US20100112037A1/en not_active Abandoned
- 2009-10-29 CN CN2009801429488A patent/CN102196820A/zh active Pending
- 2009-10-29 WO PCT/US2009/062502 patent/WO2010051349A1/en active Application Filing
- 2009-10-29 EP EP09752585A patent/EP2349334A1/en not_active Withdrawn
- 2009-10-29 CA CA2741546A patent/CA2741546A1/en not_active Abandoned
- 2009-10-30 CL CL2009002017A patent/CL2009002017A1/es unknown
- 2009-10-30 UY UY0001032214A patent/UY32214A/es not_active Application Discontinuation
- 2009-10-30 TW TW098136956A patent/TW201021790A/zh unknown
Also Published As
Publication number | Publication date |
---|---|
JP2012507546A (ja) | 2012-03-29 |
AR074062A1 (es) | 2010-12-22 |
UY32214A (es) | 2010-05-31 |
TW201021790A (en) | 2010-06-16 |
CN102196820A (zh) | 2011-09-21 |
AU2009308843A1 (en) | 2010-05-06 |
US20100112037A1 (en) | 2010-05-06 |
EP2349334A1 (en) | 2011-08-03 |
CA2741546A1 (en) | 2010-05-06 |
WO2010051349A1 (en) | 2010-05-06 |
CL2009002017A1 (es) | 2011-01-07 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
PE20100371A1 (es) | Agonistas del receptor s1p para el tratamiento de malaria cerebral | |
DK201470535A (en) | Parasiticidal oral veterinary compositions comprising systemically-acting active agents, methods and uses thereof | |
AR090349A1 (es) | Terapia de combinacion para trastornos proliferativos, kit y uso | |
CR20120663A (es) | Combinaciones que comprenden antisicóticos atípicos y agonistas taar1 | |
AR088383A1 (es) | Formulaciones de etanercept estabilizadas con combinaciones de azucares y polioles | |
GT201000095A (es) | Producto de dispersión sólida que contiene un compuesto a base de n-aril urea | |
CR20140005A (es) | Una nueva composición terapéutica que contiene apomorfina como principio activo | |
CO6280574A2 (es) | Metodos para utilizar antagonistas de vasopresina con agentes de quimioterapia con antraciclina para reducir la cardiotoxicidad y/o para mejorar la supervivencia | |
BR112015019369A2 (pt) | derivados de ácido bisfenil butanóico substituídos como inibidores de nep (endopeptidase neutra) | |
NI201400122A (es) | Agentes terapéuticos para administración subcutánea optimizados | |
PE20150345A1 (es) | Nuevo compuesto que tiene la capacidad para inhibir la enzima deshidrogenasa 11b-hidroxiesteroide tipo 1 (11b-hsd1) o sal farmaceuticamente aceptable del mismo, metodo para producir el mismo, y composicion farmaceutica que contiene el mismo como ingrediente activo | |
CO2022006645A2 (es) | Derivados de 1,2,4–oxadiazol como agonistas del receptor hepático x | |
RU2012134065A (ru) | Альфа-2 адренергический агонист, обладающий эффектом длительного снижения внутриглазного давления | |
AR095032A1 (es) | Formulaciones de compuestos orgánicos, composición farmacéutica sólida comprimida por rodillo | |
AR095220A1 (es) | Conjunto para un dispositivo de administración de fármacos | |
PE20130782A1 (es) | Composiciones farmaceuticas que consisten de paracetamol y el proceso para la preparacion del mismo | |
MX2015010434A (es) | Derivados de acido bisfenil-butanoico sustituido como inhibidores de la endopeptidasa neutra (nep), con una mayor eficacia in vivo. | |
AR095194A1 (es) | Conjunto para un dispositivo de administración de fármacos | |
AR092719A1 (es) | Metodo y composicion para el tratamiento de ectoparasitos | |
JP2014530847A5 (es) | ||
AR074441A1 (es) | Mejoramiento no quirurgico de cicatrices | |
PE20160669A1 (es) | Formas de dosificacion farmaceutica que comprenden 1-[6-(morfolin-4-il)pirimidin-4-il]-4-(1h-1,2,3-triazol-1-il)-1h-pirazol-5-olato de sodio | |
PE20160038A1 (es) | Composicion farmaceutica sinergistica de dos analgesicos con distinto perfil farmacocinetico | |
PE20100372A1 (es) | Inhibidores de la s1p liasa para el tratamiento de malaria cerebral | |
RU2013142835A (ru) | Способ лечения ишемического инсульта |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
FC | Refusal |