PE20160669A1 - Formas de dosificacion farmaceutica que comprenden 1-[6-(morfolin-4-il)pirimidin-4-il]-4-(1h-1,2,3-triazol-1-il)-1h-pirazol-5-olato de sodio - Google Patents

Formas de dosificacion farmaceutica que comprenden 1-[6-(morfolin-4-il)pirimidin-4-il]-4-(1h-1,2,3-triazol-1-il)-1h-pirazol-5-olato de sodio

Info

Publication number
PE20160669A1
PE20160669A1 PE2016000498A PE2016000498A PE20160669A1 PE 20160669 A1 PE20160669 A1 PE 20160669A1 PE 2016000498 A PE2016000498 A PE 2016000498A PE 2016000498 A PE2016000498 A PE 2016000498A PE 20160669 A1 PE20160669 A1 PE 20160669A1
Authority
PE
Peru
Prior art keywords
sodium
morfolin
pyrimidin
olate
pharmaceutical dosage
Prior art date
Application number
PE2016000498A
Other languages
English (en)
Inventor
Klaus Benke
Gabriele Winter
Heike Neumann
Michael Formell
Original Assignee
Bayer Pharma AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=49356354&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=PE20160669(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Bayer Pharma AG filed Critical Bayer Pharma AG
Publication of PE20160669A1 publication Critical patent/PE20160669A1/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A61K31/5375—1,4-Oxazines, e.g. morpholine
    • A61K31/5377—1,4-Oxazines, e.g. morpholine not condensed and containing further heterocyclic rings, e.g. timolol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2013—Organic compounds, e.g. phospholipids, fats
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2013—Organic compounds, e.g. phospholipids, fats
    • A61K9/2018—Sugars, or sugar alcohols, e.g. lactose, mannitol; Derivatives thereof, e.g. polysorbates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2086—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat
    • A61K9/209—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat containing drug in at least two layers or in the core and in at least one outer layer
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2095—Tabletting processes; Dosage units made by direct compression of powders or specially processed granules, by eliminating solvents, by melt-extrusion, by injection molding, by 3D printing
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/12—Drugs for disorders of the urinary system of the kidneys
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/06—Antianaemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Cardiology (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Urology & Nephrology (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Hospice & Palliative Care (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)

Abstract

SE REFIERE A UNA FORMA SOLIDA DE DOSIFICACION FARMACEUTICA PARA ADMINISTRACION ORAL QUE COMPRENDE: A) 1-[6-(MORFOLIN-4-IL)PIRIMIDIN-4-IL]-4-(1H-1,2,3-TRIAZOL-1-IL)-1H-PIRAZOL-5-OLATO DE SODIO COMO PRINCIPIO ACTIVO; B) UN AGENTE DE RELLENO TAL COMO CELULOSA MICROCRISTALINA O MANITOL; Y C) UN LUBRICANTE TAL COMO ESTEARIL FUMARATO DE SODIO O DIESTEARATO DE GLICERILO. DICHA COMPOSICION ES UTIL EN EL TRATAMIENTO DE TRASTORNOS CARDIOVASCULARES, FALLO CARDIACO, ANEMIA, TRASTORNOS RENALES CRONICOS E INSUFICIENCIA RENAL
PE2016000498A 2013-10-17 2014-10-13 Formas de dosificacion farmaceutica que comprenden 1-[6-(morfolin-4-il)pirimidin-4-il]-4-(1h-1,2,3-triazol-1-il)-1h-pirazol-5-olato de sodio PE20160669A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP13189145 2013-10-17

Publications (1)

Publication Number Publication Date
PE20160669A1 true PE20160669A1 (es) 2016-08-04

Family

ID=49356354

Family Applications (1)

Application Number Title Priority Date Filing Date
PE2016000498A PE20160669A1 (es) 2013-10-17 2014-10-13 Formas de dosificacion farmaceutica que comprenden 1-[6-(morfolin-4-il)pirimidin-4-il]-4-(1h-1,2,3-triazol-1-il)-1h-pirazol-5-olato de sodio

Country Status (35)

Country Link
US (1) US9827198B2 (es)
EP (1) EP3057580B1 (es)
JP (1) JP6525979B2 (es)
KR (1) KR102330953B1 (es)
CN (1) CN105636580B (es)
AP (1) AP2016009135A0 (es)
AR (1) AR098064A1 (es)
AU (1) AU2014336389B2 (es)
BR (1) BR112016007588A2 (es)
CA (1) CA2927437C (es)
CL (1) CL2016000857A1 (es)
CU (1) CU24515B1 (es)
DK (1) DK3057580T3 (es)
DO (1) DOP2016000078A (es)
EA (1) EA032932B1 (es)
ES (1) ES2868228T3 (es)
GT (1) GT201600072A (es)
HR (1) HRP20210691T1 (es)
HU (1) HUE054107T2 (es)
IL (1) IL244933B (es)
JO (1) JO3645B1 (es)
LT (1) LT3057580T (es)
MA (1) MA38974B2 (es)
MX (1) MX2016004628A (es)
MY (1) MY190202A (es)
NI (1) NI201600054A (es)
PE (1) PE20160669A1 (es)
PH (1) PH12016500716B1 (es)
SA (1) SA516370940B1 (es)
SI (1) SI3057580T1 (es)
TN (1) TN2016000135A1 (es)
TW (1) TWI746418B (es)
UA (1) UA119855C2 (es)
UY (1) UY35784A (es)
WO (1) WO2015055564A1 (es)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PT3845230T (pt) * 2018-08-31 2023-09-27 Astellas Pharma Inc Composição farmacêutica para administração oral

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102006050516A1 (de) 2006-10-26 2008-04-30 Bayer Healthcare Ag Substituierte Dihydropyrazolone und ihre Verwendung
CN101646461A (zh) * 2007-03-13 2010-02-10 大日本住友制药株式会社 口腔崩解片
DE102010044131A1 (de) * 2010-11-18 2012-05-24 Bayer Schering Pharma Aktiengesellschaft Substituiertes Natrium-1H-pyrazol-5-olat

Also Published As

Publication number Publication date
PH12016500716A1 (en) 2016-06-20
IL244933A0 (en) 2016-05-31
EP3057580B1 (de) 2021-02-24
HUE054107T2 (hu) 2021-08-30
MX2016004628A (es) 2016-08-01
SA516370940B1 (ar) 2019-11-20
UA119855C2 (uk) 2019-08-27
JO3645B1 (ar) 2020-08-27
GT201600072A (es) 2018-12-19
IL244933B (en) 2020-11-30
DK3057580T3 (da) 2021-05-10
SI3057580T1 (sl) 2021-07-30
AU2014336389A1 (en) 2016-05-12
US20160256394A1 (en) 2016-09-08
AU2014336389B2 (en) 2020-01-30
ES2868228T3 (es) 2021-10-21
CN105636580A (zh) 2016-06-01
MA38974B2 (fr) 2020-11-30
MY190202A (en) 2022-04-04
KR20160068784A (ko) 2016-06-15
CA2927437C (en) 2022-06-28
KR102330953B1 (ko) 2021-11-26
DOP2016000078A (es) 2016-08-15
CU20160048A7 (es) 2016-10-28
EA201690788A1 (ru) 2016-09-30
JP6525979B2 (ja) 2019-06-05
US9827198B2 (en) 2017-11-28
NZ718063A (en) 2021-06-25
PH12016500716B1 (en) 2016-06-20
TW201607568A (zh) 2016-03-01
JP2016538256A (ja) 2016-12-08
TN2016000135A1 (en) 2017-10-06
HRP20210691T1 (hr) 2021-06-11
TWI746418B (zh) 2021-11-21
EA032932B1 (ru) 2019-08-30
MA38974A1 (fr) 2017-05-31
CU24515B1 (es) 2021-05-12
BR112016007588A2 (pt) 2017-09-12
UY35784A (es) 2015-05-29
NI201600054A (es) 2016-09-21
EP3057580A1 (de) 2016-08-24
CN105636580B (zh) 2020-03-31
WO2015055564A1 (de) 2015-04-23
LT3057580T (lt) 2021-04-12
CL2016000857A1 (es) 2016-11-25
CA2927437A1 (en) 2015-04-23
AP2016009135A0 (en) 2016-04-30
AR098064A1 (es) 2016-04-27

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