ATE240949T1 - Epoxysuccinamid-derivate oder ihre salze - Google Patents

Epoxysuccinamid-derivate oder ihre salze

Info

Publication number
ATE240949T1
ATE240949T1 AT98914078T AT98914078T ATE240949T1 AT E240949 T1 ATE240949 T1 AT E240949T1 AT 98914078 T AT98914078 T AT 98914078T AT 98914078 T AT98914078 T AT 98914078T AT E240949 T1 ATE240949 T1 AT E240949T1
Authority
AT
Austria
Prior art keywords
substituted
group
alkyl
salt
hydrogen atom
Prior art date
Application number
AT98914078T
Other languages
English (en)
Inventor
Tetsuji Asao
Tomohiro Yamashita
Yoshimitsu Suda
Shigeo Okajima
Yukio Tada
Nobuhiko Katsunuma
Shozo Yamada
Kazuhiko Shigeno
Atsuhiko Uemura
Original Assignee
Taiho Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Taiho Pharmaceutical Co Ltd filed Critical Taiho Pharmaceutical Co Ltd
Application granted granted Critical
Publication of ATE240949T1 publication Critical patent/ATE240949T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D303/00—Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
    • C07D303/02—Compounds containing oxirane rings
    • C07D303/48—Compounds containing oxirane rings with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms, e.g. ester or nitrile radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/12—Drugs for disorders of the metabolism for electrolyte homeostasis
    • A61P3/14—Drugs for disorders of the metabolism for electrolyte homeostasis for calcium homeostasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/04—Antineoplastic agents specific for metastasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
AT98914078T 1997-04-18 1998-04-17 Epoxysuccinamid-derivate oder ihre salze ATE240949T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP10215197 1997-04-18
PCT/JP1998/001778 WO1998047887A1 (fr) 1997-04-18 1998-04-17 Nouveaux derives d'epoxysuccinamide et sels associes

Publications (1)

Publication Number Publication Date
ATE240949T1 true ATE240949T1 (de) 2003-06-15

Family

ID=14319744

Family Applications (1)

Application Number Title Priority Date Filing Date
AT98914078T ATE240949T1 (de) 1997-04-18 1998-04-17 Epoxysuccinamid-derivate oder ihre salze

Country Status (8)

Country Link
US (1) US6110967A (de)
EP (1) EP0921122B1 (de)
JP (1) JP3410476B2 (de)
AT (1) ATE240949T1 (de)
AU (1) AU727497B2 (de)
CA (1) CA2258354A1 (de)
DE (1) DE69814800T2 (de)
WO (1) WO1998047887A1 (de)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ITPD980169A1 (it) 1998-07-06 2000-01-06 Fidia Advanced Biopolymers Srl Ammidi dell'acido ialuronico e dei suoi derivati e processo per la loro preparazione.
US6620844B2 (en) * 2001-02-14 2003-09-16 Newmillennium Pharmaceutical, Inc. Method for reducing blood insulin levels by reducing in vivo cathepsin L activity
US20040009891A1 (en) * 2001-02-14 2004-01-15 Newmillennium Pharmaceutical, Inc. Method and composition for treating obesity by targeting cathepsin
KR101108722B1 (ko) * 2002-01-07 2012-02-17 에자이 알앤드디 매니지먼트 가부시키가이샤 데아자퓨린 및 이의 용도
ITPD20050056A1 (it) * 2005-03-02 2006-09-03 Fidia Farmaceutici Derivati ammidici del'acido ialuronico in osteoartrosi
WO2007038772A1 (en) * 2005-09-28 2007-04-05 American Life Science Pharmaceuticals Novel drugs for dementia
AU2007305138A1 (en) 2006-06-13 2008-04-10 The Board Of Trustees Of The Leland Stanford Junior University Epoxide inhibitors of cysteine proteases
US20100216875A1 (en) * 2006-12-20 2010-08-26 Gregory Hook Methods of treating alzheimer's disease
CN101970007A (zh) 2007-06-08 2011-02-09 日本化学医药株式会社 脑动脉瘤的治疗或预防药
US20100331545A1 (en) 2007-10-24 2010-12-30 Nippon Chemiphar Co., Ltd. Regulator for signaling toll-like receptor, which comprises cathepsin inhibitor as active ingredient
CN101967209B (zh) * 2010-10-20 2012-11-07 南京大学 一种n-乙酰基乙二胺螯合树脂及其制备方法
WO2013116663A1 (en) * 2012-02-01 2013-08-08 The Trustees Of Columbia University In The City Of New York Novel cysteine protease inhibitors and uses thereof
CN104211666B (zh) * 2013-05-31 2017-11-14 中国人民解放军军事医学科学院毒物药物研究所 2,3‑环氧丁二酰胺类化合物、其制备方法和用途

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5556853A (en) * 1993-10-29 1996-09-17 Takeda Chemical Industries, Ltd. Epoxysuccinic acid derivatives
JPH08104683A (ja) * 1993-10-29 1996-04-23 Takeda Chem Ind Ltd エポキシコハク酸誘導体
JPH08104684A (ja) * 1994-05-31 1996-04-23 Takeda Chem Ind Ltd エポキシコハク酸関連化合物
AU2537695A (en) * 1994-05-31 1995-12-21 Takeda Chemical Industries Ltd. Epoxysuccinic acid derivatives, their production and use
EP0808839B1 (de) * 1995-12-12 2001-05-23 Taiho Pharmaceutical Co., Ltd. Epoxysuccinamid-derivate oder deren salze und medikamente die diese enthalten

Also Published As

Publication number Publication date
AU727497B2 (en) 2000-12-14
DE69814800T2 (de) 2003-12-18
US6110967A (en) 2000-08-29
JP3410476B2 (ja) 2003-05-26
CA2258354A1 (en) 1998-10-29
EP0921122B1 (de) 2003-05-21
EP0921122A1 (de) 1999-06-09
EP0921122A4 (de) 2001-06-13
DE69814800D1 (de) 2003-06-26
AU6853798A (en) 1998-11-13
WO1998047887A1 (fr) 1998-10-29

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Legal Events

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RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties